JP5977331B2 - 高い嵩密度と良好な流動性を有するセルロース誘導体の製造方法 - Google Patents
高い嵩密度と良好な流動性を有するセルロース誘導体の製造方法 Download PDFInfo
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- JP5977331B2 JP5977331B2 JP2014503690A JP2014503690A JP5977331B2 JP 5977331 B2 JP5977331 B2 JP 5977331B2 JP 2014503690 A JP2014503690 A JP 2014503690A JP 2014503690 A JP2014503690 A JP 2014503690A JP 5977331 B2 JP5977331 B2 JP 5977331B2
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- Prior art keywords
- cellulose derivative
- cellulose
- airflow
- gas
- wet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B11/00—Preparation of cellulose ethers
- C08B11/20—Post-etherification treatments of chemical or physical type, e.g. mixed etherification in two steps, including purification
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
- B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
- B02C13/00—Disintegrating by mills having rotary beater elements ; Hammer mills
- B02C13/26—Details
- B02C13/288—Ventilating, or influencing air circulation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
- B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
- B02C23/00—Auxiliary methods or auxiliary devices or accessories specially adapted for crushing or disintegrating not provided for in preceding groups or not specially adapted to apparatus covered by a single preceding group
- B02C23/18—Adding fluid, other than for crushing or disintegrating by fluid energy
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
- B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
- B02C23/00—Auxiliary methods or auxiliary devices or accessories specially adapted for crushing or disintegrating not provided for in preceding groups or not specially adapted to apparatus covered by a single preceding group
- B02C23/18—Adding fluid, other than for crushing or disintegrating by fluid energy
- B02C23/24—Passing gas through crushing or disintegrating zone
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B11/00—Preparation of cellulose ethers
- C08B11/193—Mixed ethers, i.e. ethers with two or more different etherifying groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/12—Powdering or granulating
- C08J3/124—Treatment for improving the free-flowing characteristics
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
- C08L1/08—Cellulose derivatives
- C08L1/26—Cellulose ethers
- C08L1/28—Alkyl ethers
- C08L1/284—Alkyl ethers with hydroxylated hydrocarbon radicals
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
- B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
- B02C23/00—Auxiliary methods or auxiliary devices or accessories specially adapted for crushing or disintegrating not provided for in preceding groups or not specially adapted to apparatus covered by a single preceding group
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2301/00—Characterised by the use of cellulose, modified cellulose or cellulose derivatives
- C08J2301/08—Cellulose derivatives
- C08J2301/26—Cellulose ethers
- C08J2301/28—Alkyl ethers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Food Science & Technology (AREA)
- Inorganic Chemistry (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161472225P | 2011-04-06 | 2011-04-06 | |
| US61/472,225 | 2011-04-06 | ||
| PCT/US2012/031111 WO2012138532A2 (en) | 2011-04-06 | 2012-03-29 | Process for producing cellulose derivatives of high bulk density and good flowability |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014510184A JP2014510184A (ja) | 2014-04-24 |
| JP2014510184A5 JP2014510184A5 (enExample) | 2014-11-13 |
| JP5977331B2 true JP5977331B2 (ja) | 2016-08-24 |
Family
ID=45932555
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014503690A Active JP5977331B2 (ja) | 2011-04-06 | 2012-03-29 | 高い嵩密度と良好な流動性を有するセルロース誘導体の製造方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9352330B2 (enExample) |
| EP (1) | EP2694035B1 (enExample) |
| JP (1) | JP5977331B2 (enExample) |
| KR (2) | KR20180132952A (enExample) |
| CN (2) | CN103459430B (enExample) |
| BR (1) | BR112013023380B1 (enExample) |
| MX (1) | MX343509B (enExample) |
| WO (1) | WO2012138532A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2694110B2 (en) * | 2011-04-06 | 2022-06-08 | Dow Global Technologies LLC | Novel polysaccharide derivatives and dosage forms |
| KR20180132952A (ko) | 2011-04-06 | 2018-12-12 | 다우 글로벌 테크놀로지스 엘엘씨 | 높은 벌크 밀도 및 양호한 유동성의 셀룰로스 유도체를 제조하는 방법 |
| KR101936563B1 (ko) * | 2012-02-10 | 2019-01-10 | 다우 글로벌 테크놀로지스 엘엘씨 | 특정 중간 입자 길이의 셀룰로스 유도체를 포함하는 압출성형 세라믹체를 위한 조성물 |
| JP6039812B2 (ja) * | 2012-09-25 | 2016-12-07 | ダウ グローバル テクノロジーズ エルエルシー | 冷水中で高い嵩密度、良好な流動性、および/または分散性、ならびに低い溶液色を有するセルロース誘導体の製造方法 |
| KR102193811B1 (ko) * | 2012-09-27 | 2020-12-22 | 다우 글로벌 테크놀로지스 엘엘씨 | 튀김 식품의 오일 및/또는 지방 흡수를 감소시키는 방법 |
| EP2968578B1 (en) | 2013-03-12 | 2019-06-26 | Hercules LLC | Coprocessed silica coated polymer composition |
| EP3049446B1 (en) * | 2013-09-23 | 2017-05-03 | Dow Global Technologies LLC | A process for recovering an esterified cellulose ether from a reaction product mixture |
| KR102412321B1 (ko) | 2014-04-25 | 2022-06-22 | 추가이 세이야쿠 가부시키가이샤 | 4환성 화합물을 고용량 함유하는 제제 |
| BR112017025103B1 (pt) * | 2015-06-05 | 2022-05-10 | Nutrition & Biosciences Usa 1, Llc | Composição em pó |
| KR20180015662A (ko) | 2015-06-05 | 2018-02-13 | 다우 글로벌 테크놀로지스 엘엘씨 | 셀룰로오스 에테르 분말 |
| KR102519854B1 (ko) | 2016-10-07 | 2023-04-10 | 신에쓰 가가꾸 고교 가부시끼가이샤 | 히드록시알킬 알킬 셀룰로오스 및 그의 제조 방법, 및 고형 제제 |
| KR102519850B1 (ko) | 2016-10-07 | 2023-04-10 | 신에쓰 가가꾸 고교 가부시끼가이샤 | 히드록시알킬 알킬 셀룰로오스 및 그의 제조 방법, 및 고형 제제 |
| CN113117131B (zh) * | 2019-12-31 | 2023-01-03 | 广州迈普再生医学科技股份有限公司 | 一种纳米纤维微球材料及其制备方法和应用 |
| BR112023013931A2 (pt) * | 2021-01-13 | 2024-01-23 | Nutrition & Biosciences Usa 1 Llc | Método aprimorado para a preparação de celulose microcristalina coloidal |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB684561A (en) | 1949-09-22 | 1952-12-17 | British Celanese | Improvements in the manufacture of water-soluble cellulose ethers |
| US4076935A (en) * | 1974-12-13 | 1978-02-28 | Hoechst Aktiengesellschaft | Grinding method for cellulose |
| GB1514788A (en) | 1974-12-13 | 1978-06-21 | Hoechst Ag | Grinding method for cellulose |
| DE3038001A1 (de) | 1980-10-08 | 1982-05-06 | Henkel KGaA, 4000 Düsseldorf | Verfahren zur herstellung von mikropulvern aus celluloseether oder cellulose |
| US4734285A (en) | 1985-10-28 | 1988-03-29 | The Dow Chemical Company | Sustained release compositions |
| US4820813A (en) | 1986-05-01 | 1989-04-11 | The Dow Chemical Company | Grinding process for high viscosity cellulose ethers |
| DE3839831A1 (de) | 1988-11-25 | 1990-05-31 | Hoechst Ag | Verfahren und vorrichtung zur produktschonenden mahlung und gleichzeitigen trocknung von feuchten celluloseethern |
| GB2262527A (en) * | 1992-07-02 | 1993-06-23 | Dow Deutschland Inc | Process for grinding cellulose compounds |
| IT1266565B1 (it) * | 1993-07-22 | 1997-01-09 | Ct Lab Farm Srl | Composizioni farmaceutiche a rilascio controllato a base di uno o piu' sali farmaceuticamente accettabili dell'acido gamma-idrossi-butirrico. |
| US5488104A (en) | 1994-06-30 | 1996-01-30 | The Dow Chemical Company | Process for comminuting cellulose ethers |
| EP0824107A3 (de) | 1996-08-12 | 1998-04-22 | Lenzing Aktiengesellschaft | Cellulosepartikel |
| DE19641781A1 (de) * | 1996-10-10 | 1998-04-16 | Clariant Gmbh | Verfahren und Vorrichtung zum gleichzeitigen Mahlen und Trocknen eines feuchten Celluloseether enthaltenden Mahlgutes |
| DE59801854D1 (de) | 1997-01-21 | 2001-11-29 | Wolff Walsrode Ag | Verfahren zur herstellung von feinteiligen polysaccharidderivaten |
| DE19823563A1 (de) | 1998-05-27 | 1999-12-02 | Altenburger Masch Gmbh | Mahltrocknung von Zellulose-Derivaten, insbesondere Methl-Zellulose |
| DE10009409A1 (de) | 2000-02-28 | 2001-08-30 | Wolff Walsrode Ag | Verfahren zur Herstellung von pulverförmigen wasserlöslichen Cellulosederivaten |
| DE10009411A1 (de) * | 2000-02-28 | 2001-08-30 | Wolff Walsrode Ag | Verfahren zur Herstellung pulverförmiger wasserlöslicher Cellulosederivate unter Einsatz eines Wasserdampf/Inertgas-Gemisch oder Wasserdampf/Luft-Gemisch als Transport und Wärmeträgergas |
| DE10152991A1 (de) | 2001-10-26 | 2003-05-08 | Wolff Walsrode Ag | Verfahren und Vorrichtung zur Mahltrocknung |
| DE102004020686B3 (de) * | 2004-04-28 | 2006-01-05 | Se Tylose Gmbh & Co. Kg | Verfahren und Vorrichtung zur Mahlung von Cellulose |
| CN101243131B (zh) | 2005-08-16 | 2012-03-21 | 陶氏环球技术公司 | 制备具有更高粘度和细度的纤维素醚产品的方法 |
| US20070082035A1 (en) * | 2005-10-06 | 2007-04-12 | New York Blood Center, Inc. | Anti-infective hygiene products based on cellulose acetate phthalate |
| US8519120B2 (en) | 2006-08-08 | 2013-08-27 | Shin-Etsu Chemical Co., Ltd. | Methods for producing a low-substituted hydroxypropylcellulose powder |
| DE102006057188A1 (de) * | 2006-12-05 | 2008-06-12 | Dow Wolff Cellulosics Gmbh | Celluloseether für Feststoffformulierungen |
| WO2008078730A1 (ja) * | 2006-12-26 | 2008-07-03 | Translational Research, Ltd. | 経鼻投与用製剤 |
| BRPI0809282B8 (pt) | 2007-04-13 | 2021-05-25 | Dow Global Technologies Inc | material granular, material de partida para uma forma de dosagem, forma de dosagem, processo de compressão direta para preparar uma forma de dosagem, uso do material granular e processo para granular um pó de polímero |
| JP5258837B2 (ja) * | 2009-05-19 | 2013-08-07 | 信越化学工業株式会社 | 包餡食品用中種の製造方法とそれを含む食品 |
| EP2598557B1 (en) * | 2010-07-28 | 2019-03-20 | Dow Global Technologies LLC | A process for dry-grinding a polysaccharide derivative |
| KR20180132952A (ko) * | 2011-04-06 | 2018-12-12 | 다우 글로벌 테크놀로지스 엘엘씨 | 높은 벌크 밀도 및 양호한 유동성의 셀룰로스 유도체를 제조하는 방법 |
-
2012
- 2012-03-29 KR KR1020187034609A patent/KR20180132952A/ko not_active Ceased
- 2012-03-29 US US14/009,432 patent/US9352330B2/en active Active
- 2012-03-29 JP JP2014503690A patent/JP5977331B2/ja active Active
- 2012-03-29 EP EP12712851.0A patent/EP2694035B1/en active Active
- 2012-03-29 WO PCT/US2012/031111 patent/WO2012138532A2/en not_active Ceased
- 2012-03-29 KR KR1020137026351A patent/KR101960244B1/ko active Active
- 2012-03-29 CN CN201280015844.2A patent/CN103459430B/zh active Active
- 2012-03-29 BR BR112013023380-0A patent/BR112013023380B1/pt active IP Right Grant
- 2012-03-29 MX MX2013011588A patent/MX343509B/es active IP Right Grant
- 2012-03-29 CN CN201610585804.1A patent/CN106188581B/zh active Active
-
2016
- 2016-05-23 US US15/140,786 patent/US20160256390A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2694035B1 (en) | 2024-11-06 |
| KR101960244B1 (ko) | 2019-03-21 |
| BR112013023380B1 (pt) | 2021-03-23 |
| MX2013011588A (es) | 2013-12-09 |
| EP2694035A2 (en) | 2014-02-12 |
| US20160256390A1 (en) | 2016-09-08 |
| US9352330B2 (en) | 2016-05-31 |
| JP2014510184A (ja) | 2014-04-24 |
| KR20180132952A (ko) | 2018-12-12 |
| CN106188581B (zh) | 2019-08-16 |
| CN103459430A (zh) | 2013-12-18 |
| CN103459430B (zh) | 2016-08-17 |
| US20140017319A1 (en) | 2014-01-16 |
| MX343509B (es) | 2016-11-08 |
| WO2012138532A2 (en) | 2012-10-11 |
| KR20140027132A (ko) | 2014-03-06 |
| BR112013023380A2 (pt) | 2017-04-25 |
| WO2012138532A3 (en) | 2013-02-28 |
| CN106188581A (zh) | 2016-12-07 |
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