BR112013023380B1 - Processo para produzir um derivado de celulose particulado - Google Patents

Processo para produzir um derivado de celulose particulado Download PDF

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Publication number
BR112013023380B1
BR112013023380B1 BR112013023380-0A BR112013023380A BR112013023380B1 BR 112013023380 B1 BR112013023380 B1 BR 112013023380B1 BR 112013023380 A BR112013023380 A BR 112013023380A BR 112013023380 B1 BR112013023380 B1 BR 112013023380B1
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BR
Brazil
Prior art keywords
cellulose derivative
gas
cellulose
impact mill
drying
Prior art date
Application number
BR112013023380-0A
Other languages
English (en)
Portuguese (pt)
Other versions
BR112013023380A2 (pt
Inventor
Yvonne M. Goerlach-Doht
Juergen Hermanns
Marco Grossstueck
Original Assignee
Dow Global Technologies Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45932555&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112013023380(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Dow Global Technologies Llc filed Critical Dow Global Technologies Llc
Publication of BR112013023380A2 publication Critical patent/BR112013023380A2/pt
Publication of BR112013023380B1 publication Critical patent/BR112013023380B1/pt

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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B11/00—Preparation of cellulose ethers
    • C08B11/20—Post-etherification treatments of chemical or physical type, e.g. mixed etherification in two steps, including purification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C13/00—Disintegrating by mills having rotary beater elements ; Hammer mills
    • B02C13/26—Details
    • B02C13/288—Ventilating, or influencing air circulation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C23/00—Auxiliary methods or auxiliary devices or accessories specially adapted for crushing or disintegrating not provided for in preceding groups or not specially adapted to apparatus covered by a single preceding group
    • B02C23/18—Adding fluid, other than for crushing or disintegrating by fluid energy
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C23/00—Auxiliary methods or auxiliary devices or accessories specially adapted for crushing or disintegrating not provided for in preceding groups or not specially adapted to apparatus covered by a single preceding group
    • B02C23/18—Adding fluid, other than for crushing or disintegrating by fluid energy
    • B02C23/24—Passing gas through crushing or disintegrating zone
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B11/00—Preparation of cellulose ethers
    • C08B11/193—Mixed ethers, i.e. ethers with two or more different etherifying groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/12—Powdering or granulating
    • C08J3/124—Treatment for improving the free-flowing characteristics
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/08—Cellulose derivatives
    • C08L1/26—Cellulose ethers
    • C08L1/28—Alkyl ethers
    • C08L1/284—Alkyl ethers with hydroxylated hydrocarbon radicals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C23/00—Auxiliary methods or auxiliary devices or accessories specially adapted for crushing or disintegrating not provided for in preceding groups or not specially adapted to apparatus covered by a single preceding group
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2301/00—Characterised by the use of cellulose, modified cellulose or cellulose derivatives
    • C08J2301/08—Cellulose derivatives
    • C08J2301/26—Cellulose ethers
    • C08J2301/28—Alkyl ethers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Cosmetics (AREA)
BR112013023380-0A 2011-04-06 2012-03-29 Processo para produzir um derivado de celulose particulado BR112013023380B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161472225P 2011-04-06 2011-04-06
US61/472,225 2011-04-06
PCT/US2012/031111 WO2012138532A2 (en) 2011-04-06 2012-03-29 Process for producing cellulose derivatives of high bulk density and good flowability

Publications (2)

Publication Number Publication Date
BR112013023380A2 BR112013023380A2 (pt) 2017-04-25
BR112013023380B1 true BR112013023380B1 (pt) 2021-03-23

Family

ID=45932555

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013023380-0A BR112013023380B1 (pt) 2011-04-06 2012-03-29 Processo para produzir um derivado de celulose particulado

Country Status (8)

Country Link
US (2) US9352330B2 (enExample)
EP (1) EP2694035B1 (enExample)
JP (1) JP5977331B2 (enExample)
KR (2) KR20180132952A (enExample)
CN (2) CN106188581B (enExample)
BR (1) BR112013023380B1 (enExample)
MX (1) MX343509B (enExample)
WO (1) WO2012138532A2 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9352330B2 (en) * 2011-04-06 2016-05-31 Dow Global Technologies Llc Process for producing cellulose derivatives of high bulk density and good flowability
CN103501817B (zh) * 2011-04-06 2015-07-15 陶氏环球技术有限责任公司 新型多糖衍生物和剂型
CN104245627A (zh) * 2012-02-10 2014-12-24 陶氏环球技术有限责任公司 包含一定中值颗粒长度的纤维衍生物的用于挤出成型陶瓷体的组合物
WO2014052213A1 (en) * 2012-09-25 2014-04-03 Dow Global Technologies Llc Process for producing cellulose derivatives of high bulk density, good flowability and/or dispersibility in cold water as well as low solution color
US10143225B2 (en) 2012-09-27 2018-12-04 Dow Global Technologies Llc Methods for reducing oil and/or fat uptake of fried foods
CN110511440A (zh) 2013-03-12 2019-11-29 赫尔克里士公司 共处理的涂覆有硅石的聚合物组合物
EP3049446B1 (en) * 2013-09-23 2017-05-03 Dow Global Technologies LLC A process for recovering an esterified cellulose ether from a reaction product mixture
CN106456651A (zh) * 2014-04-25 2017-02-22 中外制药株式会社 以高用量含有四环性化合物的制剂
KR102696151B1 (ko) * 2015-06-05 2024-08-16 다우 글로벌 테크놀로지스 엘엘씨 셀룰로오스 에테르 분말
WO2016196152A1 (en) * 2015-06-05 2016-12-08 Dow Global Technologies Llc Cellulose ether powders
KR102519854B1 (ko) 2016-10-07 2023-04-10 신에쓰 가가꾸 고교 가부시끼가이샤 히드록시알킬 알킬 셀룰로오스 및 그의 제조 방법, 및 고형 제제
KR102519850B1 (ko) * 2016-10-07 2023-04-10 신에쓰 가가꾸 고교 가부시끼가이샤 히드록시알킬 알킬 셀룰로오스 및 그의 제조 방법, 및 고형 제제
CN113117131B (zh) * 2019-12-31 2023-01-03 广州迈普再生医学科技股份有限公司 一种纳米纤维微球材料及其制备方法和应用
WO2022152760A1 (en) * 2021-01-13 2022-07-21 Nutrition & Biosciences Usa 1, Llc Improved method for the preparation of colloidal microcrystalline cellulose
WO2022152763A1 (en) * 2021-01-13 2022-07-21 Nutrition & Biosciences Usa 1, Llc Improved method for the preparation of microcrystalline cellulose

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB684561A (en) 1949-09-22 1952-12-17 British Celanese Improvements in the manufacture of water-soluble cellulose ethers
US4076935A (en) * 1974-12-13 1978-02-28 Hoechst Aktiengesellschaft Grinding method for cellulose
GB1514788A (en) 1974-12-13 1978-06-21 Hoechst Ag Grinding method for cellulose
DE3038001A1 (de) 1980-10-08 1982-05-06 Henkel KGaA, 4000 Düsseldorf Verfahren zur herstellung von mikropulvern aus celluloseether oder cellulose
US4734285A (en) 1985-10-28 1988-03-29 The Dow Chemical Company Sustained release compositions
US4820813A (en) 1986-05-01 1989-04-11 The Dow Chemical Company Grinding process for high viscosity cellulose ethers
DE3839831A1 (de) 1988-11-25 1990-05-31 Hoechst Ag Verfahren und vorrichtung zur produktschonenden mahlung und gleichzeitigen trocknung von feuchten celluloseethern
GB2262527A (en) * 1992-07-02 1993-06-23 Dow Deutschland Inc Process for grinding cellulose compounds
IT1266565B1 (it) * 1993-07-22 1997-01-09 Ct Lab Farm Srl Composizioni farmaceutiche a rilascio controllato a base di uno o piu' sali farmaceuticamente accettabili dell'acido gamma-idrossi-butirrico.
US5488104A (en) 1994-06-30 1996-01-30 The Dow Chemical Company Process for comminuting cellulose ethers
EP0824107A3 (de) 1996-08-12 1998-04-22 Lenzing Aktiengesellschaft Cellulosepartikel
DE19641781A1 (de) 1996-10-10 1998-04-16 Clariant Gmbh Verfahren und Vorrichtung zum gleichzeitigen Mahlen und Trocknen eines feuchten Celluloseether enthaltenden Mahlgutes
EP0954536B2 (de) 1997-01-21 2009-01-07 Dow Wolff Cellulosics GmbH Verfahren zur herstellung von feinteiligen polysaccharidderivaten
DE19823563A1 (de) 1998-05-27 1999-12-02 Altenburger Masch Gmbh Mahltrocknung von Zellulose-Derivaten, insbesondere Methl-Zellulose
DE10009409A1 (de) 2000-02-28 2001-08-30 Wolff Walsrode Ag Verfahren zur Herstellung von pulverförmigen wasserlöslichen Cellulosederivaten
DE10009411A1 (de) 2000-02-28 2001-08-30 Wolff Walsrode Ag Verfahren zur Herstellung pulverförmiger wasserlöslicher Cellulosederivate unter Einsatz eines Wasserdampf/Inertgas-Gemisch oder Wasserdampf/Luft-Gemisch als Transport und Wärmeträgergas
DE10152991A1 (de) 2001-10-26 2003-05-08 Wolff Walsrode Ag Verfahren und Vorrichtung zur Mahltrocknung
DE102004020686B3 (de) * 2004-04-28 2006-01-05 Se Tylose Gmbh & Co. Kg Verfahren und Vorrichtung zur Mahlung von Cellulose
DE502006002836D1 (de) 2005-08-16 2009-03-26 Dow Wolff Cellulosics Gmbh Verfahren zur herstellung von celluloseetherprodukten mit erhöhter viskosität und feinheit
US20070082035A1 (en) * 2005-10-06 2007-04-12 New York Blood Center, Inc. Anti-infective hygiene products based on cellulose acetate phthalate
US8519120B2 (en) 2006-08-08 2013-08-27 Shin-Etsu Chemical Co., Ltd. Methods for producing a low-substituted hydroxypropylcellulose powder
DE102006057188A1 (de) * 2006-12-05 2008-06-12 Dow Wolff Cellulosics Gmbh Celluloseether für Feststoffformulierungen
CN101668544B (zh) * 2006-12-26 2013-04-24 株式会社新日本科学 经鼻投用制剂
US8877249B2 (en) 2007-04-13 2014-11-04 Dow Global Technologies Llc Granular material for dosage forms
JP5258837B2 (ja) * 2009-05-19 2013-08-07 信越化学工業株式会社 包餡食品用中種の製造方法とそれを含む食品
WO2012015400A1 (en) * 2010-07-28 2012-02-02 Dow Global Technologies Llc A process for dry-grinding a polysaccharide derivative
US9352330B2 (en) * 2011-04-06 2016-05-31 Dow Global Technologies Llc Process for producing cellulose derivatives of high bulk density and good flowability

Also Published As

Publication number Publication date
CN106188581B (zh) 2019-08-16
KR20180132952A (ko) 2018-12-12
EP2694035A2 (en) 2014-02-12
WO2012138532A2 (en) 2012-10-11
US20140017319A1 (en) 2014-01-16
CN103459430A (zh) 2013-12-18
CN106188581A (zh) 2016-12-07
CN103459430B (zh) 2016-08-17
JP2014510184A (ja) 2014-04-24
EP2694035B1 (en) 2024-11-06
US9352330B2 (en) 2016-05-31
WO2012138532A3 (en) 2013-02-28
KR101960244B1 (ko) 2019-03-21
MX2013011588A (es) 2013-12-09
BR112013023380A2 (pt) 2017-04-25
JP5977331B2 (ja) 2016-08-24
MX343509B (es) 2016-11-08
US20160256390A1 (en) 2016-09-08
KR20140027132A (ko) 2014-03-06

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 29/03/2012, OBSERVADAS AS CONDICOES LEGAIS.

B25A Requested transfer of rights approved

Owner name: THE DOW CHEMICAL COMPANY (US)

B25A Requested transfer of rights approved

Owner name: DDP SPECIALTY ELECTRONIC MATERIALS US, INC. (US)

B25D Requested change of name of applicant approved

Owner name: DDP SPECIALTY ELECTRONIC MATERIALS US, LLC (US)

B25A Requested transfer of rights approved

Owner name: NUTRITION AND BIOSCIENCES USA 1, LLC (US)