JP5971945B2 - カチオン性脂質の鏡像異性体による免疫応答の刺激 - Google Patents
カチオン性脂質の鏡像異性体による免疫応答の刺激 Download PDFInfo
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- JP5971945B2 JP5971945B2 JP2011505132A JP2011505132A JP5971945B2 JP 5971945 B2 JP5971945 B2 JP 5971945B2 JP 2011505132 A JP2011505132 A JP 2011505132A JP 2011505132 A JP2011505132 A JP 2011505132A JP 5971945 B2 JP5971945 B2 JP 5971945B2
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- antigen
- ccl
- cationic lipid
- antigens
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4583708P | 2008-04-17 | 2008-04-17 | |
| US61/045,837 | 2008-04-17 | ||
| PCT/US2009/040500 WO2009129227A1 (en) | 2008-04-17 | 2009-04-14 | Stimulation of an immune response by enantiomers of cationic lipids |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011518170A JP2011518170A (ja) | 2011-06-23 |
| JP2011518170A5 JP2011518170A5 (https=) | 2013-05-23 |
| JP5971945B2 true JP5971945B2 (ja) | 2016-08-17 |
Family
ID=41199446
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011505132A Active JP5971945B2 (ja) | 2008-04-17 | 2009-04-14 | カチオン性脂質の鏡像異性体による免疫応答の刺激 |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US9789129B2 (https=) |
| EP (1) | EP2276495B1 (https=) |
| JP (1) | JP5971945B2 (https=) |
| CN (2) | CN110075113A (https=) |
| AU (1) | AU2009236306B2 (https=) |
| BR (1) | BRPI0910464B1 (https=) |
| CA (1) | CA2721366C (https=) |
| ES (1) | ES2712505T3 (https=) |
| IL (1) | IL208713A (https=) |
| PL (1) | PL2276495T3 (https=) |
| RU (1) | RU2530555C2 (https=) |
| TW (1) | TWI449534B (https=) |
| WO (1) | WO2009129227A1 (https=) |
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| US8877206B2 (en) | 2007-03-22 | 2014-11-04 | Pds Biotechnology Corporation | Stimulation of an immune response by cationic lipids |
| EP2276495B1 (en) | 2008-04-17 | 2018-11-21 | PDS Biotechnology Corporation | Stimulation of an immune response by enantiomers of cationic lipids |
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| CA3005251A1 (en) | 2015-11-13 | 2017-05-18 | Pds Biotechnology Corporation | Lipids as synthetic vectors to enhance antigen processing and presentation ex-vivo in dendritic cell therapy |
| JP2019500021A (ja) * | 2015-11-13 | 2019-01-10 | ピーディーエス バイオテクノロジー コーポレイションPds Biotechnology Corporation | 樹状細胞療法においてex vivoでの抗原のプロセシングと提示を亢進させるための合成ベクターとしての脂質 |
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| US10874733B2 (en) * | 2016-10-31 | 2020-12-29 | Eyegene Inc. | Composition for enhancing immunity comprising immune modulator and cationic liposome, and use of same |
| WO2018224166A1 (en) | 2017-06-09 | 2018-12-13 | Biontech Rna Pharmaceuticals Gmbh | Methods for predicting the usefulness of disease specific amino acid modifications for immunotherapy |
| WO2019113200A1 (en) | 2017-12-05 | 2019-06-13 | Pds Biotechnology Corporation | Methods and compositions comprising cationic lipids for stimulating type 1 interferon genes |
| CN114980919B (zh) * | 2019-11-18 | 2026-04-14 | 儿童医学中心公司 | 过度活化驻留树突状细胞的刺激物用于癌症免疫疗法 |
| CN116782892A (zh) * | 2020-11-20 | 2023-09-19 | Pds生物科技公司 | 用于通过直接肿瘤注射进行免疫治疗的方法和包含阳离子脂质的组合物 |
| US20240317828A1 (en) * | 2022-10-19 | 2024-09-26 | Pds Biotechnology Corporation | T cell activating immunotherapeutic for treatment of mucin 1 protein expressing human cancers |
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| US20200330491A1 (en) | 2020-10-22 |
| JP2011518170A (ja) | 2011-06-23 |
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| US20110110972A1 (en) | 2011-05-12 |
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| US10702541B2 (en) | 2020-07-07 |
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| EP2276495A1 (en) | 2011-01-26 |
| CA2721366A1 (en) | 2009-10-22 |
| US20210308157A1 (en) | 2021-10-07 |
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| EP2276495B1 (en) | 2018-11-21 |
| CN102137675A (zh) | 2011-07-27 |
| TWI449534B (zh) | 2014-08-21 |
| US20180015114A1 (en) | 2018-01-18 |
| RU2530555C2 (ru) | 2014-10-10 |
| CA2721366C (en) | 2017-06-06 |
| US11801257B2 (en) | 2023-10-31 |
| TW201000124A (en) | 2010-01-01 |
| IL208713A0 (en) | 2010-12-30 |
| AU2009236306B2 (en) | 2015-04-02 |
| US9789129B2 (en) | 2017-10-17 |
| RU2010146655A (ru) | 2012-05-27 |
| BRPI0910464A2 (pt) | 2018-03-27 |
| ES2712505T3 (es) | 2019-05-13 |
| BRPI0910464B1 (pt) | 2021-08-10 |
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