CA2721366C - Stimulation of an immune response by enantiomers of cationic lipids - Google Patents

Stimulation of an immune response by enantiomers of cationic lipids Download PDF

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Publication number
CA2721366C
CA2721366C CA2721366A CA2721366A CA2721366C CA 2721366 C CA2721366 C CA 2721366C CA 2721366 A CA2721366 A CA 2721366A CA 2721366 A CA2721366 A CA 2721366A CA 2721366 C CA2721366 C CA 2721366C
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Prior art keywords
antigen
ccl
pharmaceutical composition
dotap
cationic lipid
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CA2721366A
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French (fr)
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CA2721366A1 (en
Inventor
Elizabeth Ann Vasievich
Weihsu Chen
Kenya Toney
Gregory Conn
Frank Bedu-Addo
Leaf Huang
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PDS Biotechnology Corp
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PDS Biotechnology Corp
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2721366A 2008-04-17 2009-04-14 Stimulation of an immune response by enantiomers of cationic lipids Active CA2721366C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4583708P 2008-04-17 2008-04-17
US61/045,837 2008-04-17
PCT/US2009/040500 WO2009129227A1 (en) 2008-04-17 2009-04-14 Stimulation of an immune response by enantiomers of cationic lipids

Publications (2)

Publication Number Publication Date
CA2721366A1 CA2721366A1 (en) 2009-10-22
CA2721366C true CA2721366C (en) 2017-06-06

Family

ID=41199446

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2721366A Active CA2721366C (en) 2008-04-17 2009-04-14 Stimulation of an immune response by enantiomers of cationic lipids

Country Status (13)

Country Link
US (4) US9789129B2 (https=)
EP (1) EP2276495B1 (https=)
JP (1) JP5971945B2 (https=)
CN (2) CN102137675A (https=)
AU (1) AU2009236306B2 (https=)
BR (1) BRPI0910464B1 (https=)
CA (1) CA2721366C (https=)
ES (1) ES2712505T3 (https=)
IL (1) IL208713A (https=)
PL (1) PL2276495T3 (https=)
RU (1) RU2530555C2 (https=)
TW (1) TWI449534B (https=)
WO (1) WO2009129227A1 (https=)

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