JP5924010B2 - Dentifrice composition - Google Patents

Description

  The present invention relates to a dentifrice composition that has a good foaming feeling with good foaming, good foaming performance, good foaming performance, sufficient toothpaste, and no irritation or bitterness.

In recent years, sales of portable electric toothbrushes have been strong, and the number of people who take oral care on the go is increasing.
However, as a dentifrice to be used in combination, there are many people using a conventional preparation containing 130 g, and such a capacity is not suitable for offices that are difficult to carry and place. On the other hand, there is a dentifrice with a capacity of 30 g for portable use, but this is limited in the number of times of use due to its small capacity and not suitable for continuous use.

  Considering these situations, it is desired to develop a dentifrice that can be used the same number of times as a normal size even in a small-sized container excellent in portability. However, in order to use the same number of times as the normal size with a small amount, it is necessary to reduce the amount of use once, but if the amount of use (usually about 1g) is reduced with existing products, foaming will be less There was a problem that it was unsatisfactory at the time of use. An increase in the amount of an anionic surfactant is effective for ensuring foaming, but when an anionic surfactant is added in an amount that can ensure sufficient foaming even when a small amount of the preparation is used, irritation occurs. Therefore, it was not possible to improve foam performance and use feeling with the above preparation.

Patent Document 1; JP-A-2006-347987 uses 1.7% by mass or more of an anionic surfactant and a nonionic surfactant in combination as an oral composition with moderate foaming and reduced irritation. Technology has been proposed. However, this is a combination of the above surfactants with xanthan gum and alginate to improve foaming properties, and is not due to the combined use of surfactants. In addition, there is no mention of the actual feeling of brushing teeth.
Patent Document 2; Japanese Patent Application Laid-Open No. 10-72342 defines a ratio of a nonionic surfactant to an anionic surfactant as a means for removing surfactant irritation in an aqueous composition. There is no mention of improving foaming or foam retention.

JP 2006-347987 A JP-A-10-72342

Therefore, in the dentifrice composition, it has been a problem to give excellent foam performance and a toothpaste feeling even when used in a small amount.
The present invention has been made to solve the above-mentioned problems, and is a dentifrice that has a good feeling of use without causing irritation and bitterness, with moderate foaming, good foam retention, sufficient toothpaste when used in a small amount. An object is to provide a composition.

As a result of intensive studies to achieve the above object, the present inventor contains (A) an anionic surfactant, (B) a nonionic surfactant, and (C) an amphoteric surfactant, and ( The total amount of A), (B) and (C) component is 4.5-12 mass%, (B) component / (A) component is 0.5-3 as mass ratio, and (D) Containing 55 to 65% by mass of sugar alcohol and / or polyhydric alcohol, it has excellent foaming performance that can ensure adequate foaming and foam retention with a small amount of use, and gives sufficient toothpaste feeling, and also stimulates It was found that a toothpaste composition having no bitterness and good usability can be obtained.

  That is, an increase in the amount of anionic surfactant is effective for improving foaming of the dentifrice composition, but if the amount is increased, irritation occurs during brushing. In addition, just increasing the amount of anionic surfactant in the conventional dentifrice composition, the disappearance of the preparation in the oral cavity is quick when used in a small amount, and an appropriate amount of foam cannot be ensured, and the teeth are brushed. The problem of not being able to give a real feeling occurred. Moreover, the problem of a taste fall also arose by increasing the amount of anionic surfactant. In addition, when the amount of the preparation used at one time is small, irritation and taste reduction are reduced to some extent. However, as described above, foam retention at the time of brushing and the actual feeling of brushing have become technical problems. On the other hand, the inventor surprisingly combined the components (A), (B), and (C) to make the total amount of these components a specific range and blend the component (D) in an appropriate amount. The above problems have been solved, and the foaming and toothbrushing feelings that can not be obtained simply by increasing the amount of anionic surfactant can be sufficiently secured, and the problems of taste and irritation can be solved at the same time. Even if the amount of the preparation used is less than usual, the foaming is moderately foamed when brushing, the amount of foam is ensured, and the spread of the preparation in the oral cavity is moderate, giving the user the feeling of brushing their teeth, It discovered that there existed an effect.

Therefore, the present invention
(A) 1.8-5 mass% anionic surfactant,
(B) 0.9-6 mass% nonionic surfactant,
(C) an amphoteric surfactant containing and 0.6-1.8 wt%, (A), the total amount of (B) and (C) component is 4.5 to 12 mass%, (B And (D) (D-1) a sugar alcohol and / or (D-2) a polyhydric alcohol selected from propylene glycol and glycerin . toothpaste compositions characterized by containing 65% by weight, and the toothpaste composition contained in the container can be taken out 0.1~0.5g use amount of one To provide dentifrice products .

  According to the present invention, it is possible to provide a dentifrice composition having a good feeling of use without causing irritation and bitterness, with a moderate amount of foaming and good foam retention when used in a small amount, giving sufficient toothpaste.

  The present invention will be described in further detail below. The dentifrice composition of the present invention contains (A) an anionic surfactant, (B) a nonionic surfactant, and (C) an amphoteric surfactant, and (A), (B) and (C). The total amount of the components is an appropriate amount, and (D) contains a specific amount of sugar alcohol and / or polyhydric alcohol.

Component (A): Anionic surfactant Examples of the anionic surfactant include alkyl sulfates, alkyl ether sulfates, alkylbenzenes having 8 to 18 carbon atoms, particularly 10 to 16 carbon atoms, such as sodium lauryl sulfate and sodium myristyl sulfate. Examples thereof include N-acyl amino acid salts such as sulfonate, sodium lauroyl sarcosine, sodium N-lauroyl-L-glutamate, N-acylmethyl taurate, alkyl ether acetate, and the like. Examples of these salts include alkali metal salts such as sodium salts. Of these, alkyl sulfates, particularly sodium lauryl sulfate, are more preferred because they can ensure excellent foam performance.

  The compounding amount of the component (A) is preferably 1.8 to 5% (mass%, the same applies hereinafter) of the total composition, more preferably 2 to 4%, from the viewpoint of foaming and securing the amount of foam when used in a small amount. . If it is less than 1.8%, foaming may not be ensured even if it is used in a small amount, or the amount of foam may not be secured and foam retention may be inferior. If it exceeds 5%, irritation and bitterness may occur, and the kneaded skin during low-temperature storage may deteriorate.

Component (B): Nonionic surfactant As the nonionic surfactant, those usually added to a dentifrice composition can be used, but the type to which ethylene oxide is added is particularly preferable, and the average added mole number of ethylene oxide is particularly preferable. (Hereinafter abbreviated as EO addition mole number) is 2 to 20 moles and the alkyl group has 14 to 18 carbon atoms and / or E.O. O. A polyoxyethylene hydrogenated castor oil having an addition mole number of 5 to 30 mol is preferred. These can be used alone or in combination of two or more.

In this case, the carbon number of the alkyl group of polyoxyethylene alkyl is preferably 14-18, particularly preferably 16 (cetyl) -18 (stearyl). O. The added mole number is preferably 2 to 20 moles, particularly preferably 5 to 10 moles. If the alkyl group has less than 14 carbon atoms or more than 18 carbon atoms, the foam retention may be poor or the taste may be poor. E. O. When the number of added moles is less than 2 moles or more than 20 moles, the foam retention may be poor or the taste may be poor.
E. of polyoxyethylene hydrogenated castor oil O. The added mole number is preferably 5 to 30 moles, particularly preferably 5 to 20 moles. E. O. When the number of added moles is less than 5 moles or more than 30 moles, the foam retention may be poor or the taste may be poor.

Examples of the polyoxyethylene alkyl ether include EMALEX 105, 107, 605, 608 (manufactured by Nippon Emulsion Co., Ltd.), BLAUNON SR-705, 707 (manufactured by Aoki Oil & Fat Co., Ltd.) and the like.
As polyoxyethylene hydrogenated castor oil, for example, NIKKOL HCO-5, HCO-10, HCO-20, HCO-30 (manufactured by Nikko Chemicals), BLAUNON CW-3, 10, PCW-20 (Aoki Oil & Fat Industry) Etc.).

  The blending amount of the component (B) is preferably 0.9 to 6%, more preferably 0.9 to 4% of the entire composition from the viewpoint of ensuring foam retention and taste. If it is less than 0.9%, the amount of foam cannot be secured by suppressing irritation, or the foam retention may be inferior. If it exceeds 6%, foaming may occur and the taste may be inferior.

In addition, the blending amount of the (B) component with respect to the (A) component is preferably (B) / (A) in a mass ratio of 0.5 to 3, more preferably from the viewpoint of foaming, foam retention, and irritation reduction. It is 7-2.8, More preferably, it is 1.0-2.5. If it is less than 0.5, irritation may be suppressed and the amount of foam may not be secured, or foam retention may be inferior. If it exceeds 3, foaming may be inferior.
In particular, it is preferable that the component (A) is an alkyl sulfate and (B) / (A) is in the above ratio for the expression of effects.

Component (C): Amphoteric Surfactant As the amphoteric surfactant, a betaine-based one is preferable. For example, an alkylbetaine-based, fatty acid amidopropylbetaine-based, or alkylimidazolinium betaine-based amphoteric surfactant can be used.
Specifically, alkyldimethylaminoacetic acid betaine such as lauryldimethylaminoacetic acid betaine, 2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine, coconut oil fatty acid amide propyldimethylaminoacetic acid betaine, coconut oil fatty acid amide And propylbetaine. These can be blended singly or in combination of two or more. Among them, coconut oil fatty acid amidopropyl betaine, 2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine has no taste or bitterness. From the point, it is more preferable.

  Specific examples of amphoteric surfactants include lauryldimethylaminoacetic acid betaine aqueous solution marketed by Nikko Chemicals Co., Ltd. under the trade name NIKKOL AM-301, Lion Co., Ltd. under the trade name Enagicol C-40H, and Levon 105. 2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine sold by Sanyo Chemical Industries, Ltd., and palm oil fatty acid sold by Nikko Chemicals Co., Ltd. under the trade name NIKKOL AM-3130N Degussa. As amidopropyldimethylaminoacetic acid betaine aqueous solution, trade name TEGO BetainCK, TEGO BetaF50, TEGO BetainZF. And coconut oil fatty acid amide propyl betaine sold by Sanyo Chemical Industries, Ltd. as Lebon 2000.

  The blending amount of the component (C) is preferably 0.6 to 1.8%, more preferably 0.9 to 1.6% of the whole composition from the viewpoint of foaming and taste. If it is less than 0.6%, foaming may not be satisfied, and if it exceeds 1.8%, the taste may deteriorate.

  In the present invention, it is important to use the components (A), (B) and (C) in combination, and that the total amount of these components is appropriate for improving the effect, particularly improving the foam performance. The total amount of the components (A), (B) and (C) is 4.5 to 12%, more preferably 5 to 8% of the entire composition. If it is less than 4.5%, foaming is inferior and the object of the present invention cannot be achieved. If it exceeds 12%, the taste is poor and the feeling of use is poor.

Component (D): Sugar alcohol and / or polyhydric alcohol Here, the polyhydric alcohol is an alcohol in which two or more of the hydrogen atoms of the aliphatic hydrocarbon are substituted with hydroxyl groups. The sugar alcohol is a chain alcohol in which the carbonyl group of the sugar molecule is reduced.
Examples of the sugar alcohol and / or polyhydric alcohol include sugar alcohols such as sorbitol, xylitol, and erythritol, and polyhydric alcohols such as propylene glycol and glycerin, and sorbitol, xylitol, propylene glycol, and glycerin are particularly preferable. These can be used individually by 1 type or in combination of 2 or more type from the point of effect expression.

  The blending amount of component (D) is 55 to 65%, preferably 55 to 60% of the entire composition from the viewpoint of suppressing the spread of the preparation. If it is less than 55%, the preparation spreads in the oral cavity during tooth brushing, disperses and disappears, and the tooth brushing feeling cannot be given. If it exceeds 65%, the taste is poor. Moreover, formulation may become difficult.

  The dentifrice composition of the present invention can be prepared in the form of solid, liquid, liquid, paste, gel, etc., and can be made into various dosage forms such as toothpaste, liquid dentifrice, liquid dentifrice, and toothpaste. The manufacturing method can adopt a conventional method according to the dosage form. In this case, appropriate known components can be blended in addition to the components described above, depending on the purpose of the composition, dosage form, and the like. For example, in the case of toothpastes, active ingredients such as abrasives such as silica-based abrasives, binders, thickeners, surfactants, preservatives, sweeteners such as sodium saccharin, colorants, fragrances, fluorides, etc. Etc., and these components and water can be mixed and manufactured. In addition, what is necessary is just to mix | blend these arbitrary components in a normal quantity as needed.

  The dentifrice composition of the present invention is housed in a small-capacity container that is easy to carry and does not bother the place of storage, and can be suitably used for portable use. In this case, it can be accommodated in a small capacity of, for example, 50 g or less, particularly 20 to 30 g, which is smaller than the general dentifrice preparation capacity (about 100 to 150 g).

The composition of the present invention is preferably a dentifrice composition of 0.1 to 0.5 g, more preferably 0.1 to 0.4 g, and still more preferably 0.1 to 0.3 g as a single use amount. A thing can be taken out and stored in a container or the like.
The composition of the present invention is excellent in foaming and foam retention even when the amount of use at one time as described above is small, gives satisfactory toothpaste, and has a good feeling of use without irritation and bitterness.

  EXAMPLES Hereinafter, although an Example and a comparative example are shown and this invention is demonstrated concretely, this invention is not restrict | limited to the following Example. In the following examples, “%” means “% by mass” unless otherwise specified.

[Examples and Comparative Examples]
Dentifrice compositions (toothpastes) having the compositions shown in Tables 1 to 3 were prepared by a conventional method. The obtained dentifrice composition was evaluated as a test preparation by the following method, and the results are shown in Tables 1 to 3. In the following, POE is an abbreviation for polyoxyethylene, and the number in parentheses after POE is the average added mole number of POE.

<Evaluation method for foaming when brushing teeth>
Evaluation was conducted by a sensory test using 10 expert panelists. About 0.2 g of the dentifrice composition was placed on a toothbrush and brushed for 3 minutes. The foaming of the dentifrice composition in the oral cavity during use was evaluated according to the following criteria.
4 points: Sufficient bubbling 3 points: Moderate bubbling 2 points: Little bubbling 1 point: Little bubbling Average evaluation results of 10 people, ◎ and bubbling were secured according to the following criteria It was judged that this was a dentifrice composition that gave good foaming when brushed.
◎: 3.5 points or more and 4.0 points or less ○: 3.0 points or more and less than 3.5 points △: 2.0 points or more and less than 3.0 points ×: Less than 2.0 points

<Evaluation method of foam retention when brushing teeth>
Evaluation was conducted by a sensory test using 10 expert panelists. About 0.2 g of the dentifrice composition was placed on a toothbrush and brushed for 3 minutes. The foaming of the dentifrice composition in the oral cavity during use was evaluated according to the following criteria.
4 points: Sufficient foam retention 3 points: Moderate foam retention 2 points: Low foam retention 1 point: Almost no foam retention Average results of evaluation of 10 people What was ensured to have foam retention was judged to be a dentifrice composition with good foam retention when brushed.
◎: 3.5 points or more and 4.0 points or less ○: 3.0 points or more and less than 3.5 points △: 2.0 points or more and less than 3.0 points ×: Less than 2.0 points

<Method for evaluating spread of dentifrice composition>
About 0.2 g of the test preparation was weighed into a test tube, twice the amount of distilled water was added, and the remaining condition of the test dentifrice on the test tube wall when shaken 10 times was evaluated according to the following criteria.
◎: Almost paste remains on the wall of the test tube ○: More than half of the paste remains on the wall of the test tube ×: No paste remains on the wall of the test tube The spreadability of the agent composition in the oral cavity was judged, and those for which the evaluations of ◎ and ○ were ensured based on the above criteria were judged to be excellent in spreadability.
In this case, excellent spreadability means that the dentifrice composition remains in an appropriate manner without being immediately dispersed / disappeared in the oral cavity during brushing, and can give the user a feeling of brushing his teeth. is there.

<Evaluation method for lack of stimulation>
Evaluation was conducted by a sensory test using 10 expert panelists. About 0.2 g of the dentifrice composition was placed on a toothbrush and brushed for 3 minutes, and the irritation felt during use was evaluated according to the following criteria.
4 points: no stimulation at all 3 points: little stimulation 2 points: some stimulation 1 point: there is stimulation Average evaluation results of 10 people, and ◎ and ○ evaluations are secured according to the following criteria Was determined to be an unstimulated dentifrice composition.
◎: 3.5 points or more and 4.0 points or less ○: 3.0 points or more and less than 3.5 points △: 2.0 points or more and less than 3.0 points ×: Less than 2.0 points

<Evaluation method for bitterness>
Evaluation was conducted by a sensory test using 10 expert panelists. About 0.2 g of the dentifrice composition was placed on a toothbrush and brushed for 3 minutes. The bitter taste felt during use was evaluated according to the following criteria.
4 points: no bitterness 3 points: bitter 2 points: slightly bitter 1 point: bitterness Average results of 10 people's evaluations are evaluated, and ◎ and ○ evaluations are secured according to the following criteria, bitterness The dentifrice composition was judged to be free of dentifrice.
◎: 3.5 points or more and 4.0 points or less ○: 3.0 points or more and less than 3.5 points △: 2.0 points or more and less than 3.0 points ×: Less than 2.0 points

The detail of the raw material used for preparation of the dentifrice composition of each case is as follows.
Sodium lauryl sulfate (manufactured by Toho Chemical Industry Co., Ltd.)
Sodium myristyl sulfate (NIKKOL SMS, manufactured by Nikko Chemicals Co., Ltd.)
Lauroyl sarcosine sodium (Soipon SLP, manufactured by Kawaken Fine Chemical Co., Ltd.)
N-lauroyl-L-glutamate sodium (Amisoft LS-11, manufactured by Ajinomoto Healthy Supply Co., Ltd.)
POE (20) hydrogenated castor oil (BLAUNON PCW-20, manufactured by Aoki Oil & Fat Co., Ltd.)
POE (5) stearyl ether (BLAUNON SR-705, manufactured by Aoki Oil & Fat Co., Ltd.)
Palm oil fatty acid amidopropyl betaine (30% aqueous solution, Levon 2000, manufactured by Sanyo Chemical Industries, Ltd.)
2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine (49% aqueous solution, Levon 105, manufactured by Sanyo Chemical Industries, Ltd.)
Xylitol (manufactured by Rocket)
Propylene glycol (Asahi Glass Co., Ltd.)
Glycerin (concentrated glycerin, manufactured by Lion Corporation)
Sorbit (70% aqueous solution, made by Rocket)
The coconut oil fatty acid amidopropyl betaine is a 30% aqueous solution and 2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine is a 49% aqueous solution. The compounding amount of 2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine showed a value converted into a pure component. Also, for sorbit, a dentifrice composition was prepared using a 70% aqueous solution product, but the compounding amount showed a pure conversion value.

  Further examples are shown below. All of these dentifrice compositions had good foaming and foam retention, gave a sufficient toothpaste, and had a good feeling of use without irritation and bitterness.

[Example 24]
Sodium lauryl sulfate 2.0%
POE (20) hydrogenated castor oil 3.0
Palm oil fatty acid amidopropyl betaine 1.35
Propylene glycol 3.0
Sorbit 28.0
Glycerin 21.0
Xylitol 6.0
Sodium fluoride 0.21
Sodium alginate 0.3
Sodium polyacrylate 0.3
Xanthan gum 0.7
Silicic anhydride (thickening) 1.0
Silicic anhydride (abrasive) 7.0
Saccharin sodium 0.25
Fragrance 0.25
Purified water balance total 100.0%

[Example 25]
Sodium myristyl sulfate 2.0%
POE (20) hydrogenated castor oil 3.0
Palm oil fatty acid amidopropyl betaine 1.35
Propylene glycol 3.0
Sorbit 28.0
Glycerin 21.0
Xylitol 6.0
Sodium fluoride 0.21
Sodium alginate 0.3
Sodium polyacrylate 0.2
Xanthan gum 0.8
Silicic anhydride (thickening) 1.0
Silicic anhydride (abrasive) 7.0
Saccharin sodium 0.25
Fragrance 0.25
Purified water balance total 100.0%

Claims (7)

(A) 1.8-5 mass% anionic surfactant,
(B) 0.9-6 mass% nonionic surfactant,
(C) an amphoteric surfactant containing and 0.6-1.8 wt%, (A), the total amount of (B) and (C) component is 4.5 to 12 mass%, (B And (D) (D-1) a sugar alcohol and / or (D-2) a polyhydric alcohol selected from propylene glycol and glycerin . toothpaste composition characterized by containing 65% by weight. (A) component toothpaste composition of claim 1 wherein the alkyl sulfate. Component (B) is an average addition mole number of polyoxyethylene alkyl ether and / or ethylene oxide in which the average addition mole number of ethylene oxide is 2 to 20 moles and the carbon number of the alkyl group is 14 to 18 moles. polyoxyethylene hardened castor oil in a claim 1 or 2 toothpaste composition. Component (C), alkyl betaine, fatty acid amide propyl betaine and alkyl betaine least one betaine selected from ampholytic surfactant and a claim 1, 2 or 3 claim of toothpaste Composition. The toothpaste composition according to any one of claims 1 to 4, wherein the component (D-1) is a sugar alcohol selected from sorbitol, xylitol, and erythritol. The toothpaste composition according to any one of claims 1 to 5, wherein the toothpaste composition is used for a toothpaste product having a single use amount of 0.1 to 0.5 g. A dentifrice product in which the toothpaste composition according to any one of claims 1 to 5 is contained in a container capable of taking out 0.1 to 0.5 g as a single use amount.