JP5894157B2 - キナーゼｐ７０Ｓ６Ｋの阻害剤としての二環式アザ複素環式カルボキサミド - Google Patents

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Publication number

JP5894157B2

JP5894157B2 JP2013520993A JP2013520993A JP5894157B2 JP 5894157 B2 JP5894157 B2 JP 5894157B2 JP 2013520993 A JP2013520993 A JP 2013520993A JP 2013520993 A JP2013520993 A JP 2013520993A JP 5894157 B2 JP5894157 B2 JP 5894157B2

Authority

JP

Japan

Prior art keywords

methyl

ethyl

methylamino

substituted methylene

amino

Prior art date

2010-07-29

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired - Fee Related

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• 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 97
• 238000000034 method Methods 0.000 claims description 82
• 150000003839 salts Chemical class 0.000 claims description 56
• 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 claims description 53
• 239000012453 solvate Substances 0.000 claims description 46
• 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 30
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• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 21
• 125000000250 methylamino group Chemical group [H]N(*)C([H])([H])[H] 0.000 claims description 21
• 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 20
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• 125000000217 alkyl group Chemical group 0.000 claims description 7
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