JP5887090B2 - 花粉症予防用液剤 - Google Patents
花粉症予防用液剤 Download PDFInfo
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- JP5887090B2 JP5887090B2 JP2011218127A JP2011218127A JP5887090B2 JP 5887090 B2 JP5887090 B2 JP 5887090B2 JP 2011218127 A JP2011218127 A JP 2011218127A JP 2011218127 A JP2011218127 A JP 2011218127A JP 5887090 B2 JP5887090 B2 JP 5887090B2
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Description
<1>L−ピロリドンカルボン酸の銀塩または亜鉛塩を含有する。
<2>さらに、カルボキシメチルセルロースを含有する。
<3>さらに、エポキシアルコキシシランを含有する。
<4>さらに、ポリビニルアルコール、ポリアクリル酸のうちの少なくともいずれかを含む。
<5>エポキシアルコキシシランが、γ−グリシドキシプロピルトリメトキシシランである。
<1>花粉への添加による花粉破壊作用の確認
スギの雄花から採取した花粉をスライドガラスに取り、ここに水を添加し、花粉の形態変化を観察した。
<2>花粉症予防用液剤の作製
以下の手順で、花粉症予防用液剤を作製した。
(1)銀0.1molとL−ピロリドンカルボン酸0.1molを混合し反応させアミノ酸銀を得た。
(2)亜鉛0.1molとL−ピロリドンカルボン酸0.1molを混合し反応させアミノ酸亜鉛を得た。
(3)上記アミノ酸銀とアミノ酸亜鉛を、1:2に配合して、水に分散させ、アミノ酸銀とアミノ酸亜鉛を総量の7.5%含む溶液とした。
(4)さらにγ−グリシドキシプロピルトリメトキシシランを総量の0.5%混合し反応させた。
(5)次に、0.2%ポリアクリル酸溶液を総量の1%混合した。
(6)次に、2%ポリビニルアルコール溶液を総量の8%混合した。
(7)次に、1%カルボキシメチルセルロース1%溶液を総量の10%混合した。
(8)1%チタネートカップリング剤溶液を総量の1%混合した。
(9)2%硫酸亜鉛七水和物溶液を総量の0.5%混合した。
(10)4%水酸化ナトリウム溶液を総量の0.8%混合した。
(11)クエン酸を総量の0.01%混合した。
<3>繊維製品への塗布による花粉破壊作用の確認
上記<2>の手順で作製した花粉症予防用液剤を繊維製品に塗布し、花粉破壊作用を検討した。
(1)マスクを約5cm×2cmの大きさにカットしたマスク片を用意し、以下のように条件を設定した。
(2)スギの雄花から採取した花粉を綿棒に取り、マスク片の表面に擦り付けた。これをシャーレに移して蓋をして、インキュベータを25℃(湿度10%〜20%)に設定した。
(3)0時間、6時間、12時間経過毎にマスク片を取り出し、花粉の形態を顕微鏡観察した。
(4)結果を表1に示す。破壊された花粉が多数確認された場合は○、破壊された花粉が確認されなかった場合は×、破壊された花粉がわずかに確認された場合は△と評価した。
<4>自然気化による花粉破壊作用の確認
上記<2>の手順で作製した花粉症予防用液剤を繊維製品に塗布し、花粉破壊作用を検討した。
(1)スギの雄花から採取した花粉を綿棒に取り、2区画に分けたスライドガラス上に載せ、これを9枚用意し、以下のように条件を設定した。
実施例3:シャーレに花粉症予防用液剤を40ml入れたものを実施例3とした。
(2)シャーレ上にスライドガラスを固定し、蓋付き容器に入れた。そして、インキュベータ内の温度を25℃に設定し、インキュベートを開始した。
(3)0時間、6時間、12時間経過毎にスライドガラスを取り出し、花粉の形態を顕微鏡観察した。
(4)結果を表2に示す。
Claims (7)
- L−ピロリドンカルボン酸の銀塩または亜鉛塩を含有することを特徴とする花粉症予防用液剤。
- さらに、カルボキシメチルセルロースを含有することを特徴とする請求項1の花粉症予防用液剤。
- さらに、エポキシアルコキシシランを含有することを特徴とする請求項1または2の花粉症予防用液剤。
- さらに、ポリビニルアルコール、ポリアクリル酸のうちの少なくともいずれかを含むことを特徴とする請求項1から3のいずれかの花粉症予防用液剤。
- エポキシアルコキシシランが、γ−グリシドキシプロピルトリメトキシシランであることを特徴とする請求項3の花粉症予防用液剤。
- 請求項1から5のいずれかの花粉症予防用液剤が塗布されていることを特徴とする花粉症予防用繊維製品。
- 請求項1から6のいずれかの花粉症予防用液剤を含むことを特徴とする花粉症予防用雑貨。
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