JP5868980B2 - トリプタミン誘導体、その製造方法および胃疾患についての使用 - Google Patents

トリプタミン誘導体、その製造方法および胃疾患についての使用 Download PDF

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Publication number
JP5868980B2
JP5868980B2 JP2013528778A JP2013528778A JP5868980B2 JP 5868980 B2 JP5868980 B2 JP 5868980B2 JP 2013528778 A JP2013528778 A JP 2013528778A JP 2013528778 A JP2013528778 A JP 2013528778A JP 5868980 B2 JP5868980 B2 JP 5868980B2
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Japan
Prior art keywords
compound
gastric
indol
sega
ethyl
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Expired - Fee Related
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JP2013528778A
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English (en)
Japanese (ja)
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JP2014506230A5 (enExample
JP2014506230A (ja
Inventor
バンディオパダヤイ，ウダイ
パル，チンマイ
ビンドゥ，サミク
セカール アディカリ，スサンタ
セカール アディカリ，スサンタ
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University of Calcutta
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University of Calcutta
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Publication of JP2014506230A5 publication Critical patent/JP2014506230A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2013528778A 2010-09-14 2011-09-14 トリプタミン誘導体、その製造方法および胃疾患についての使用 Expired - Fee Related JP5868980B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN2173DE2010 2010-09-14
IN2173/DEL/2010 2010-09-14
PCT/IB2011/002129 WO2012035406A1 (en) 2010-09-14 2011-09-14 Tryptamine derivatives, their preparation and their use in gastropathy

Publications (3)

Publication Number Publication Date
JP2014506230A JP2014506230A (ja) 2014-03-13
JP2014506230A5 JP2014506230A5 (enExample) 2014-05-22
JP5868980B2 true JP5868980B2 (ja) 2016-02-24

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ID=44898070

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013528778A Expired - Fee Related JP5868980B2 (ja) 2010-09-14 2011-09-14 トリプタミン誘導体、その製造方法および胃疾患についての使用

Country Status (4)

Country Link
US (1) US8901317B2 (enExample)
EP (1) EP2616439B1 (enExample)
JP (1) JP5868980B2 (enExample)
WO (1) WO2012035406A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102439852B1 (ko) * 2015-04-17 2022-09-05 가천대학교 산학협력단 2-아미노퀴놀린-8-올 유도체, 및 이의 용도
US20190083462A1 (en) * 2016-03-18 2019-03-21 The Texas A&M University System Prevention of nsaid enteropathy with microbiota-derived tryptophan-metabolite
CA3176091C (en) 2020-12-31 2023-07-25 1280225 B.C. Ltd. Method of synthesizing indole compounds
CN113880749B (zh) * 2021-10-11 2023-06-30 江南大学 化合物JNc-463的制备方法及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3345376A (en) * 1963-11-06 1967-10-03 Upjohn Co Polyhydro-6-methoxy-1-(3, 4, 5-trimethoxyphenyl)-9h-pyrido[3, 4-b]indoles
DE68925135T2 (de) * 1988-02-25 1996-08-01 I F L O S A S Di Giorgio E Ald Verfahren zur totalen Synthese von einer Indol-Struktur-Verbindungsklasse des Tryptamin-Typs, insbesondere Melatonin- oder N-Acetyl-5-methoxytryptamin mit hoher Reinheit und Löslichkeit, verwendbar in der AIDS-Therapie
CA2110574A1 (en) * 1991-06-21 1993-01-07 Lawrence I. Kruse Tryptamine analogues, their synthesis and their use as 5-ht1-like or 5-ht2 receptor agonists
US6403808B1 (en) * 1999-12-10 2002-06-11 Virginia Commonwealth University Selective 5-HT6 receptor ligands
JP4156825B2 (ja) * 2001-11-01 2008-09-24 株式会社ロッテ 抗鬱・抗ストレス剤及びそれを含有する組成物
CN1729174B (zh) * 2002-12-20 2015-10-21 西巴特殊化学品控股有限公司 胺的合成以及用于合成胺的中间体
JP3964417B2 (ja) * 2004-09-27 2007-08-22 国立大学法人金沢大学 インドール誘導体を有効成分とするα２受容体遮断剤及び血管拡張剤
JP5370957B2 (ja) * 2008-08-20 2013-12-18 学校法人日本大学 アポトーシス抑制剤

Also Published As

Publication number Publication date
EP2616439A1 (en) 2013-07-24
US8901317B2 (en) 2014-12-02
EP2616439B1 (en) 2015-12-16
JP2014506230A (ja) 2014-03-13
WO2012035406A1 (en) 2012-03-22
US20130197052A1 (en) 2013-08-01

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