JP5848608B2 - 喘息、結核及び肺癌の診断及び疾患管理のための呼気分析システム及び方法 - Google Patents

喘息、結核及び肺癌の診断及び疾患管理のための呼気分析システム及び方法 Download PDF

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JP5848608B2
JP5848608B2 JP2011538714A JP2011538714A JP5848608B2 JP 5848608 B2 JP5848608 B2 JP 5848608B2 JP 2011538714 A JP2011538714 A JP 2011538714A JP 2011538714 A JP2011538714 A JP 2011538714A JP 5848608 B2 JP5848608 B2 JP 5848608B2
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ambient air
portable device
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detector array
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JP2012510319A5 (enExample
JP2012510319A (ja
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リーペン ワン
リーペン ワン
チーリン ヤン
チーリン ヤン
チェンリン ファン
チェンリン ファン
ツンクアン エー. チョウ
ツンクアン エー. チョウ
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Tricorntech Corp Taiwan
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Measuring devices for evaluating the respiratory organs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Measuring devices for evaluating the respiratory organs
    • A61B5/082Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Measuring devices for evaluating the respiratory organs
    • A61B5/097Devices for facilitating collection of breath or for directing breath into or through measuring devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/41Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/411Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02Details of sensors specially adapted for in-vivo measurements
    • A61B2562/028Microscale sensors, e.g. electromechanical sensors [MEMS]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N2030/022Column chromatography characterised by the kind of separation mechanism
    • G01N2030/025Gas chromatography
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/497Physical analysis of biological material of gaseous biological material, e.g. breath
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/497Physical analysis of biological material of gaseous biological material, e.g. breath
    • G01N33/4975Physical analysis of biological material of gaseous biological material, e.g. breath other than oxygen, carbon dioxide or alcohol, e.g. organic vapours

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physiology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
JP2011538714A 2008-12-01 2009-11-30 喘息、結核及び肺癌の診断及び疾患管理のための呼気分析システム及び方法 Active JP5848608B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11897708P 2008-12-01 2008-12-01
US61/118,977 2008-12-01
PCT/US2009/066103 WO2010065452A1 (en) 2008-12-01 2009-11-30 Breath analysis systems and methods for asthma, tuberculosis and lung cancer diagnostics and disease management

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JP2012510319A JP2012510319A (ja) 2012-05-10
JP2012510319A5 JP2012510319A5 (enExample) 2015-09-17
JP5848608B2 true JP5848608B2 (ja) 2016-01-27

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US (2) US10568541B2 (enExample)
EP (1) EP2369989A4 (enExample)
JP (1) JP5848608B2 (enExample)
CN (2) CN104856679B (enExample)
WO (1) WO2010065452A1 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021041571A1 (en) * 2019-08-26 2021-03-04 Zeteo Tech, Inc. Diagnosis of tuberculosis and other diseases using exhaled breath
US11839463B2 (en) 2020-04-03 2023-12-12 Zeteo Tech, Inc. Diagnosis of respiratory diseases using analysis of exhaled breath and aerosols
KR102817329B1 (ko) * 2023-02-08 2025-06-05 재단법인 대구경북첨단의료산업진흥재단 호기 가스 분석을 통한 폐질환 진단 시스템 및 이의 제어 방법
US12364411B2 (en) 2020-04-03 2025-07-22 Zeteo Tech, Inc. Diagnosis of respiratory diseases using analysis of exhaled breath and aerosols

Families Citing this family (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2858236B1 (fr) 2003-07-29 2006-04-28 Airox Dispositif et procede de fourniture de gaz respiratoire en pression ou en volume
US8302602B2 (en) 2008-09-30 2012-11-06 Nellcor Puritan Bennett Llc Breathing assistance system with multiple pressure sensors
EP2369989A4 (en) * 2008-12-01 2013-05-15 Tricorntech Corp ATTA ANALYSIS SYSTEM AND ASSAYS FOR THE DIAGNOSIS AND TREATMENT OF ASTHMA, TUBERCULOSIS AND LUNG CANCER
US8434479B2 (en) 2009-02-27 2013-05-07 Covidien Lp Flow rate compensation for transient thermal response of hot-wire anemometers
US8439036B2 (en) 2009-12-01 2013-05-14 Covidien Lp Exhalation valve assembly with integral flow sensor
US8469030B2 (en) * 2009-12-01 2013-06-25 Covidien Lp Exhalation valve assembly with selectable contagious/non-contagious latch
US8439037B2 (en) 2009-12-01 2013-05-14 Covidien Lp Exhalation valve assembly with integrated filter and flow sensor
US8469031B2 (en) 2009-12-01 2013-06-25 Covidien Lp Exhalation valve assembly with integrated filter
US9315848B2 (en) 2010-08-18 2016-04-19 Technion Research And Development Foundation Ltd. Volatile organic compounds for detecting cell dysplasia and genetic alterations associated with lung cancer
GB201018692D0 (en) * 2010-11-05 2010-12-22 Univ Manchester Biomarkers
US9629971B2 (en) 2011-04-29 2017-04-25 Covidien Lp Methods and systems for exhalation control and trajectory optimization
RU2466730C1 (ru) * 2011-11-09 2012-11-20 Государственное бюджетное образовательное учреждение высшего профессионального образования "Омская государственная медицинская академия" Министерства здравоохранения и социального развития Российской Федерации (ГБОУ ВПО ОмГМА Минздравсоцразвития России) Способ подготовки к пробе манту с 2 те ппд-л у детей с отягощенным аллергическим анамнезом
US9528979B2 (en) 2011-11-15 2016-12-27 Technion Research And Development Foundation Ltd. Breath analysis of pulmonary nodules
US9364624B2 (en) 2011-12-07 2016-06-14 Covidien Lp Methods and systems for adaptive base flow
US9498589B2 (en) 2011-12-31 2016-11-22 Covidien Lp Methods and systems for adaptive base flow and leak compensation
TWI458464B (zh) * 2012-02-01 2014-11-01 Nat Univ Tsing Hua 可早期偵測及辨識肺炎種類之呼吸器、其氣體辨識晶片、及其氣體辨識方法
US9770192B2 (en) * 2012-03-19 2017-09-26 Richard C. Fuisz Method and system to amplify and measure breath analytes
US9144658B2 (en) 2012-04-30 2015-09-29 Covidien Lp Minimizing imposed expiratory resistance of mechanical ventilator by optimizing exhalation valve control
US9164080B2 (en) 2012-06-11 2015-10-20 Ohio State Innovation Foundation System and method for sensing NO
JP5723421B2 (ja) * 2012-07-20 2015-05-27 福永生物科技股▲ふん▼有限公司EPS Bio Technology Corp. 電子鼻装置
JP2014023603A (ja) * 2012-07-25 2014-02-06 Nippon Koden Corp 睡眠時無呼吸判定装置
WO2014068554A1 (en) * 2012-10-29 2014-05-08 Technion Research And Development Foundation Ltd. Sensor technology for diagnosing tuberculosis
JP6159821B2 (ja) * 2012-12-26 2017-07-05 アール バイオ カンパニー リミテッドR Bio Co., Ltd. 呼吸ガスを利用した癌の診断方法
USD731049S1 (en) 2013-03-05 2015-06-02 Covidien Lp EVQ housing of an exhalation module
USD744095S1 (en) 2013-03-08 2015-11-24 Covidien Lp Exhalation module EVQ internal flow sensor
USD693001S1 (en) 2013-03-08 2013-11-05 Covidien Lp Neonate expiratory filter assembly of an exhalation module
USD736905S1 (en) 2013-03-08 2015-08-18 Covidien Lp Exhalation module EVQ housing
USD731065S1 (en) 2013-03-08 2015-06-02 Covidien Lp EVQ pressure sensor filter of an exhalation module
USD692556S1 (en) 2013-03-08 2013-10-29 Covidien Lp Expiratory filter body of an exhalation module
USD701601S1 (en) 2013-03-08 2014-03-25 Covidien Lp Condensate vial of an exhalation module
USD731048S1 (en) 2013-03-08 2015-06-02 Covidien Lp EVQ diaphragm of an exhalation module
US9950135B2 (en) 2013-03-15 2018-04-24 Covidien Lp Maintaining an exhalation valve sensor assembly
JP6182796B2 (ja) * 2013-06-28 2017-08-23 国立研究開発法人産業技術総合研究所 呼気分析システム、肺がんマーカー及び呼気分析方法
HK1214651A1 (zh) * 2013-08-28 2016-07-29 路易斯威尔大学研究基金会有限公司 利用呼出氣體的肺癌的非侵入性檢測
KR101489093B1 (ko) * 2013-11-06 2015-02-06 경희대학교 산학협력단 호흡 훈련 장치 및 방법
WO2015124468A1 (en) * 2014-02-19 2015-08-27 Koninklijke Philips N.V. Method of detecting ards and systems for detecting ards
US10307080B2 (en) 2014-03-07 2019-06-04 Spirosure, Inc. Respiratory monitor
JP6256986B2 (ja) * 2014-03-28 2018-01-10 学校法人順天堂 食道癌の判定方法
US9366664B2 (en) 2014-05-21 2016-06-14 Andas Inc. Device for measurement of exhaled nitric oxide concentration
US9011779B1 (en) 2014-05-21 2015-04-21 Andas Inc. Device for measurement of exhaled ethanol concentration
DE102014210574A1 (de) * 2014-06-04 2015-12-17 Robert Bosch Gmbh Messvorrichtung und Verfahren zur Bestimmung der asthmatisch wirksamen Belastung bei einem Menschen oder Tier
US20170160265A1 (en) * 2014-07-21 2017-06-08 Technion Research & Development Foundation Ltd. Compositions for direct breath sampling
US11262354B2 (en) 2014-10-20 2022-03-01 Boston Scientific Scimed, Inc. Disposable sensor elements, systems, and related methods
GB201502447D0 (en) * 2015-02-13 2015-04-01 Univ Liverpool Method and apparatus for sample analysis
CN106137204A (zh) * 2015-04-02 2016-11-23 中国科学院生态环境研究中心 利用真空紫外光电离质谱仪进行肺癌早期筛查的方法
USD775345S1 (en) 2015-04-10 2016-12-27 Covidien Lp Ventilator console
KR101813553B1 (ko) * 2015-05-20 2017-12-29 박종복 호기 가스 성분을 이용한 비접촉식 스위치
CN104970775A (zh) * 2015-07-01 2015-10-14 深圳市前海安测信息技术有限公司 肺结核病早期症状监测方法及监测系统
US20170059554A1 (en) * 2015-09-02 2017-03-02 R. J. Reynolds Tobacco Company Method for monitoring use of a tobacco product
EP3143930A1 (en) * 2015-09-21 2017-03-22 Université de Liège Method for the diagnosis of airway disease inflammatory subtype
US20170191910A1 (en) * 2015-12-31 2017-07-06 The Cleveland Clinic Foundation Method, computing device and system for collecting exhaled breath
CN108701496A (zh) 2016-03-01 2018-10-23 皇家飞利浦有限公司 用于确定呼吸发作的风险水平的系统和方法
US20210236745A1 (en) 2016-05-03 2021-08-05 Pneuma Respiratory, Inc. Droplet delivery device for delivery of fluids to the pulmonary system and methods of use
WO2017192782A1 (en) * 2016-05-03 2017-11-09 Pneuma Respiratory, Inc. Systems and methods comprising a droplet delivery device and a breathing assist device for therapeutic treatment
US11191457B2 (en) 2016-06-15 2021-12-07 Boston Scientific Scimed, Inc. Gas sampling catheters, systems and methods
CN106361343A (zh) * 2016-08-31 2017-02-01 王未来 一种智能峰流速仪及管控使用方法
WO2018075731A1 (en) 2016-10-21 2018-04-26 Boston Scientific Scimed, Inc. Gas sampling device
CN106422744B (zh) * 2016-11-09 2023-03-14 暨南大学 一次性手术烟雾净化器
JP2020510831A (ja) 2017-03-01 2020-04-09 日本特殊陶業株式会社 還元ガスを用いた一酸化窒素検出装置
JP6879545B2 (ja) * 2017-03-15 2021-06-02 株式会社タニタ 生体ガス検知装置、方法、及びプログラム
EP3602044A4 (en) 2017-03-23 2021-05-05 Technion Research & Development Foundation Limited Device and methods for detection and monitoring of tuberculosis
EP3624678B1 (en) 2017-05-19 2022-08-17 Boston Scientific Scimed Inc. Systems and methods for assessing the health status of a patient
CN110799231B (zh) 2017-05-19 2022-08-02 精呼吸股份有限公司 干粉输送装置及其使用方法
US10852264B2 (en) 2017-07-18 2020-12-01 Boston Scientific Scimed, Inc. Systems and methods for analyte sensing in physiological gas samples
CA3077475A1 (en) 2017-10-04 2019-04-11 Pneuma Respiratory, Inc. Electronic breath actuated in-line droplet delivery device and methods of use
EP3697481B1 (en) 2017-10-17 2024-05-22 Pneuma Respiratory, Inc. Nasal drug delivery apparatus and methods of use
CN111479604B (zh) 2017-11-08 2022-12-30 精呼吸股份有限公司 具有小体积安瓿的电动呼吸致动直列液滴输送装置及使用方法
CN111801048A (zh) * 2018-02-20 2020-10-20 明尼苏达大学董事会 呼吸取样面罩和系统
DE102018114970A1 (de) * 2018-06-21 2019-12-24 breazy-health GmbH System und Verfahren zur Bereitstellung von zumindest einer Information über zumindest eine Wechselwirkung zwischen Umgebungsluft und Atemfunktion von einem Individuum
US20210186367A1 (en) * 2018-09-03 2021-06-24 Kozhnosys Private Limited System for detection of volatile organic compounds (voc) in exhaled breath for health monitoring
US20210405023A1 (en) * 2018-10-06 2021-12-30 The Cleveland Clinic Foundation Method for diagnosing clostridioides difficile infection
EP3867639A1 (en) 2018-10-19 2021-08-25 Regents of the University of Minnesota Systems and methods for detecting a brain condition
WO2020112027A1 (en) * 2018-11-28 2020-06-04 National University Of Singapore Method of detecting cancer and/or tuberculosis
EP3861329A1 (en) 2018-11-27 2021-08-11 Boston Scientific Scimed Inc. Systems and methods for detecting a health condition
EP3899515B1 (en) 2018-12-18 2023-01-25 Boston Scientific Scimed Inc. Systems and methods for measuring kinetic response of chemical sensor elements comprising graphene varactors
EP3962358A1 (en) 2019-04-29 2022-03-09 Regents of the University of Minnesota Systems and methods for assessing and treating hemorrhage and other conditions
CN110179467B (zh) * 2019-05-29 2023-11-14 中国医学科学院生物医学工程研究所 一种用于肺癌诊断的呼吸采样装置
EP4013302A1 (en) 2019-08-13 2022-06-22 Respiration Scan Ltd System and method for determining onset and disease progression
CN114651178A (zh) 2019-09-10 2022-06-21 波士顿科学国际有限公司 气体测量装置和方法
GB201914183D0 (en) * 2019-10-01 2019-11-13 Owlstone Med Ltd Biomarker
CN110755056A (zh) * 2019-11-21 2020-02-07 中国中医科学院 医生四诊过程记录仪
US11054347B1 (en) * 2019-12-31 2021-07-06 X Development Llc Enhanced gas sensor selectivity
BR102020002883A2 (pt) * 2020-02-11 2021-08-24 Nathalia Moraes Do Nascimento Método para identificação e monitoramento de doenças a partir de amostras de gases captadas por um dispositivo e método de treinamento de uma rede neural para identificação de doenças a partir de amostras de gases captadas por um dispositivo
US11896767B2 (en) 2020-03-20 2024-02-13 Covidien Lp Model-driven system integration in medical ventilators
JP7755314B2 (ja) * 2020-06-17 2025-10-16 株式会社レボーン システム、情報処理装置及びプログラム
WO2022004590A1 (ja) * 2020-06-29 2022-01-06 パナソニックIpマネジメント株式会社 ガスセンサ
CN111784683B (zh) * 2020-07-10 2022-05-17 天津大学 病理切片检测方法及装置、计算机设备及存储介质
IT202000032249A1 (it) * 2020-12-23 2022-06-23 Eurotech Spa Apparato di identificazione di stati patologici e relativo metodo
US12480907B2 (en) 2021-04-16 2025-11-25 Regents Of The University Of Minnesota Systems utilizing graphene varactor hysteresis effects for sample characterization
EP4659870A2 (en) 2021-06-22 2025-12-10 Pneuma Respiratory, Inc. Droplet delivery device with push ejection
EP4119046A1 (en) 2021-07-13 2023-01-18 Universitäts-kinderspital Beider Basel Method for processing mass spectrometry data obtained from breath gas
CN113588821A (zh) * 2021-07-29 2021-11-02 中国科学院合肥物质科学研究院 一种用于口腔气味检测识别的方法
CN114431854A (zh) * 2021-12-23 2022-05-06 新绎健康科技有限公司 基于呼吸气的数字闻诊检测装置及其检测方法
CN114720542B (zh) * 2022-03-30 2025-08-05 北京大学人民医院 基于hppi-tofms的早期肺癌诊断呼出气标志物筛选及其应用
KR20250038748A (ko) 2022-07-18 2025-03-19 뉴마 레스퍼러토리 인코포레이티드 작은 스텝 크기 및 고해상도 에어로졸 생성 시스템 및 방법
WO2024168414A1 (pt) 2023-02-16 2024-08-22 Gustavo Senna Chelles Coletor de amostras de ar expirado para pré-diagnóstico de patologias e seu método de uso
WO2025080232A1 (en) * 2023-10-11 2025-04-17 Karamanoğlu Mehmetbey Üni̇versi̇tesi̇ Strateji̇ Geli̇şti̇rme Dai̇resi̇ Başkanliği Psoriasis disease diagnosis system and method using electronic nose from person's breathing information
WO2025117806A1 (en) * 2023-11-30 2025-06-05 Arizona Board Of Regents On Behalf Of Arizona State University Volatile biomarkers for discriminating valley fever from other lung infections

Family Cites Families (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4888295A (en) 1984-03-02 1989-12-19 The United States Of America As Represented By The United States Department Of Energy Portable system and method combining chromatography and array of electrochemical sensors
US4869876A (en) * 1984-04-30 1989-09-26 International Business Machines Corp. Multi-purpose plural-oven gas chromatography system with shared controls
JPS6378943A (ja) 1986-09-19 1988-04-09 鹿島建設株式会社 スラブの構築方法
US4796639A (en) * 1987-11-05 1989-01-10 Medical Graphics Corporation Pulmonary diagnostic system
JPH06764Y2 (ja) * 1987-11-17 1994-01-05 フィガロ技研株式会社 ガス検出装置
FI82367C (fi) 1988-02-11 1991-03-11 Instrumentarium Oy Till intubationsroer kopplad spirometer och provtagningsfoerbindning i gasanalysator.
US4850371A (en) * 1988-06-13 1989-07-25 Broadhurst John H Novel endotracheal tube and mass spectrometer
US5081871A (en) * 1989-02-02 1992-01-21 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Breath sampler
JPH0647047A (ja) 1992-06-03 1994-02-22 Hideo Ueda 臨床用呼気検査方法及び装置
CA2097363A1 (en) 1992-06-03 1993-12-04 Hideo Ueda Expired air examination device and method for clinical purpose
JP3838671B2 (ja) * 1993-10-25 2006-10-25 アークレイ株式会社 呼気採取装置
JPH07184488A (ja) 1993-12-24 1995-07-25 Kyowa Kk 養液栽培システム
US5465728A (en) 1994-01-11 1995-11-14 Phillips; Michael Breath collection
DE892926T1 (de) * 1996-04-09 1999-12-09 Sievers Instruments, Inc. Verfahren und vorrichtung zur messung von bestandteilen in von menschen ausgeatmeter luft
US5996586A (en) 1997-03-26 1999-12-07 Phillips; Michael Breath test for detection of lung cancer
SE9801532D0 (sv) 1998-04-30 1998-04-30 Aerocrine Ab Device for the collection of exhaled air samples
WO1999065386A1 (en) 1998-06-15 1999-12-23 The Trustees Of The University Of Pennsylvania Diagnosing intrapulmonary infection and analyzing nasal sample
EP1099102B1 (en) 1998-06-19 2008-05-07 California Institute Of Technology Trace level detection of analytes using artificial olfactometry
EP1117991A4 (en) 1998-10-02 2005-04-27 California Inst Of Techn CONDUCTIVE ORGANIC SENSORS, MOSAIC SENSORS AND METHODS OF USE
GB9825904D0 (en) 1998-11-27 1999-01-20 Univ Cranfield Diagnosis of gastric and lung disorders
US6468222B1 (en) * 1999-08-02 2002-10-22 Healthetech, Inc. Metabolic calorimeter employing respiratory gas analysis
AU2001275290A1 (en) * 2000-06-07 2001-12-17 Healthetech, Inc. Breath ketone analyzer
US6981947B2 (en) * 2002-01-22 2006-01-03 University Of Florida Research Foundation, Inc. Method and apparatus for monitoring respiratory gases during anesthesia
US7076371B2 (en) 2001-03-03 2006-07-11 Chi Yung Fu Non-invasive diagnostic and monitoring method and apparatus based on odor detection
US20100248268A1 (en) * 2001-03-27 2010-09-30 Woods Daniel F Methods to utilize invertebrate chemosensory proteins for industrial and commercial uses
AU2002309803A1 (en) * 2001-04-17 2002-10-28 University Of Virginia Patent Foundation Breath test for assessing diseases, particularly asthma
DE10121262A1 (de) 2001-04-30 2002-11-14 Siemens Ag Vorrichtung zur quantitativen Messung von Stickoxiden in der Ausatemluft und Verwendung
US20030023181A1 (en) * 2001-07-26 2003-01-30 Mault James R. Gas analyzer of the fluorescent-film type particularly useful for respiratory analysis
US6726637B2 (en) 2001-12-06 2004-04-27 Michael Phillips Breath collection apparatus
US7473229B2 (en) * 2001-12-10 2009-01-06 Pranalytica, Inc. Method of analyzing components of alveolar breath
AU2003207552A1 (en) 2002-01-29 2003-09-02 James D. Talton Methods of collecting and analyzing human breath
WO2003075745A2 (en) 2002-03-04 2003-09-18 Cyrano Sciences, Inc. Detection, diagnosis, and monitoring of a medical condition or disease with artificial olfactometry
US7101340B1 (en) * 2002-04-12 2006-09-05 Braun Charles L Spectroscopic breath profile analysis device and uses thereof for facilitating diagnosis of medical conditions
ES2311264T3 (es) * 2002-09-16 2009-02-01 Aerocrine Ab Aparato y metodo para analisis de gas para diagnostico.
US20050150778A1 (en) 2002-11-18 2005-07-14 Lewis Nathan S. Use of basic polymers in carbon black composite vapor detectors to obtain enhanced sensitivity and classification performance for volatile fatty acids
WO2004090534A1 (en) * 2003-04-01 2004-10-21 The Charles Stark Draper Laboratory, Inc. Non-invasive breath analysis using field asymmetric ion mobility spectrometry
US7172557B1 (en) * 2003-08-29 2007-02-06 Caldyne, Inc. Spirometer, display and method
EP1751537B1 (en) 2004-05-17 2019-07-10 Firmenich SA Multidimensional gas chromatography apparatus and analyte transfer procedure using a multiple-cool strand interface
WO2006046588A1 (ja) * 2004-10-28 2006-05-04 Seems Inc. 疾病診断システム
US7421882B2 (en) * 2004-12-17 2008-09-09 University Of Iowa Research Foundation Breath-based sensors for non-invasive molecular detection
EP1850749A2 (en) 2005-01-10 2007-11-07 Pulmatrix, Inc. Method and device for decreasing contamination
JP5075638B2 (ja) * 2005-01-10 2012-11-21 プルマトリックス,インコーポレイティッド 汚染を減少させるための方法及び装置
US7695681B2 (en) * 2005-03-31 2010-04-13 Intel Corporation Miniature chemical analysis system
US7343779B1 (en) * 2005-12-05 2008-03-18 Yu Conrad M High performance, hand-held gas chromatograph, method and system
US8117896B2 (en) * 2006-08-09 2012-02-21 Seacoast Science, Inc. Preconcentrators and methods of making and using the same
WO2008126519A1 (ja) * 2007-03-22 2008-10-23 Shinshu University センサー
US20080275355A1 (en) * 2007-05-04 2008-11-06 Ekips Technologies, Inc. Method For Diagnosing An Infectioin Condition
EP2176670A4 (en) * 2007-08-08 2017-07-12 Invoy Technologies, LLC Biosensor system with a multifunctional portable electronic device
US9521963B2 (en) * 2008-05-13 2016-12-20 Ric Investments, Llc Respiratory component measurement system with indicating elements
US8087283B2 (en) * 2008-06-17 2012-01-03 Tricorntech Corporation Handheld gas analysis systems for point-of-care medical applications
JP5289837B2 (ja) * 2008-06-30 2013-09-11 日本光電工業株式会社 生体由来ガス成分分析装置及び疾病判定支援装置
US8652064B2 (en) * 2008-09-30 2014-02-18 Covidien Lp Sampling circuit for measuring analytes
EP2369989A4 (en) * 2008-12-01 2013-05-15 Tricorntech Corp ATTA ANALYSIS SYSTEM AND ASSAYS FOR THE DIAGNOSIS AND TREATMENT OF ASTHMA, TUBERCULOSIS AND LUNG CANCER
US8716655B2 (en) * 2009-07-02 2014-05-06 Tricorntech Corporation Integrated ion separation spectrometer
US8999245B2 (en) * 2009-07-07 2015-04-07 Tricorn Tech Corporation Cascaded gas chromatographs (CGCs) with individual temperature control and gas analysis systems using same
US8707760B2 (en) * 2009-07-31 2014-04-29 Tricorntech Corporation Gas collection and analysis system with front-end and back-end pre-concentrators and moisture removal
US8978444B2 (en) * 2010-04-23 2015-03-17 Tricorn Tech Corporation Gas analyte spectrum sharpening and separation with multi-dimensional micro-GC for gas chromatography analysis

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021041571A1 (en) * 2019-08-26 2021-03-04 Zeteo Tech, Inc. Diagnosis of tuberculosis and other diseases using exhaled breath
US12019056B2 (en) 2019-08-26 2024-06-25 Zeteo Tech, Inc. Diagnosis of tuberculosis and other diseases using exhaled breath
US20240345042A1 (en) * 2019-08-26 2024-10-17 Zeteo Tech, Inc. Diagnosis of tuberculosis and other diseases using exhaled breath
US12467910B2 (en) * 2019-08-26 2025-11-11 Zeteo Tech, Inc. Diagnosis of tuberculosis and other diseases using exhaled breath
US11839463B2 (en) 2020-04-03 2023-12-12 Zeteo Tech, Inc. Diagnosis of respiratory diseases using analysis of exhaled breath and aerosols
US12364411B2 (en) 2020-04-03 2025-07-22 Zeteo Tech, Inc. Diagnosis of respiratory diseases using analysis of exhaled breath and aerosols
KR102817329B1 (ko) * 2023-02-08 2025-06-05 재단법인 대구경북첨단의료산업진흥재단 호기 가스 분석을 통한 폐질환 진단 시스템 및 이의 제어 방법

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US10568541B2 (en) 2020-02-25
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