JP5846608B2 - ｉＰＳ細胞由来の神経細胞を用いた蛋白質ミスフォールディング病の診断方法 - Google Patents

ｉＰＳ細胞由来の神経細胞を用いた蛋白質ミスフォールディング病の診断方法 Download PDF

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JP5846608B2
JP5846608B2 JP2012540193A JP2012540193A JP5846608B2 JP 5846608 B2 JP5846608 B2 JP 5846608B2 JP 2012540193 A JP2012540193 A JP 2012540193A JP 2012540193 A JP2012540193 A JP 2012540193A JP 5846608 B2 JP5846608 B2 JP 5846608B2
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cells
cell
amount
disease
protein
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JP2013520960A (ja
JP2013520960A5 (enExample
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治久 井上
治久 井上
志保 北岡
志保 北岡
八幡　直樹
直樹 八幡
修永 岩田
修永 岩田
隆臣 西道
隆臣 西道
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Kyoto University
RIKEN
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2012540193A 2010-03-03 2011-03-03 ｉＰＳ細胞由来の神経細胞を用いた蛋白質ミスフォールディング病の診断方法 Expired - Fee Related JP5846608B2 (ja)

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US30992710P 2010-03-03 2010-03-03
US61/309,927 2010-03-03
PCT/JP2011/055570 WO2011108766A1 (en) 2010-03-03 2011-03-03 METHOD FOR DIAGNOSING A PROTEIN MISFOLDING DISEASE USING NERVE CELLS DERIVED FROM iPS CELLS

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JP2013520960A JP2013520960A (ja) 2013-06-10
JP2013520960A5 JP2013520960A5 (enExample) 2014-06-26
JP5846608B2 true JP5846608B2 (ja) 2016-01-20

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Publication number Priority date Publication date Assignee Title
US8642334B2 (en) 2009-02-17 2014-02-04 Memorial Sloan Kettering Cancer Center Methods of neural conversion of human embryonic stem cells
ES2747803T3 (es) * 2010-05-25 2020-03-11 Memorial Sloan Kettering Cancer Center Método de diferenciación a nociceptores de células madre embrionarias humanas y sus usos
AU2012332269B2 (en) 2011-11-04 2018-05-31 Memorial Sloan-Kettering Cancer Center Midbrain dopamine (DA) neurons for engraftment
WO2013140927A1 (ja) * 2012-03-21 2013-09-26 国立大学法人京都大学 アルツハイマー病の治療薬および/または予防薬のスクリーニング方法
JP6756610B2 (ja) 2013-04-26 2020-09-16 メモリアル スローン ケタリング キャンサー センター 多分化能細胞および多能性細胞の分化を方向付けることによって発生させる皮質介在ニューロンおよびその他のニューロン細胞
US20160030484A1 (en) * 2014-08-04 2016-02-04 University Of Kansas Mammalian pluripotent stem cells, methods for their production, and uses thereof
EP3315604A4 (en) 2015-06-25 2018-12-26 Kaneka Corporation Liquid injection method
EP3817753A1 (en) * 2018-07-03 2021-05-12 Universidad del País Vasco - Euskal Herriko Unibertsitatea Cellular aggregates for use in vascularisation therapy
WO2020165615A1 (en) * 2019-02-14 2020-08-20 Omnion Research International D.O.O. Method of transformation of hair folicle cells into neurons, method and scale for estimating risk for onset of a particular brain disease
JP7333579B2 (ja) * 2019-05-08 2023-08-25 国立大学法人東京工業大学 アルツハイマー疾患モデル神経細胞及びその製造方法、並びにその神経細胞を用いたアルツハイマー病作用薬物のスクリーニング方法
EP3978595A4 (en) * 2019-05-31 2023-07-05 Kyoto University INFORMATION PROCESSING DEVICE, SCREENING DEVICE, INFORMATION PROCESSING METHOD, SCREENING METHOD AND PROGRAM
WO2020241836A1 (ja) * 2019-05-31 2020-12-03 国立大学法人京都大学 情報処理装置、スクリーニング装置、情報処理方法、スクリーニング方法、及びプログラム

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ATE481498T1 (de) * 2002-04-26 2010-10-15 Takeda Pharmaceutical Verfahren zur messung von neprilysinaktivität
WO2004081172A2 (en) 2003-03-12 2004-09-23 Reliance Life Sciences Pvt. Ltd. Derivation of terminally differentiated dopaminergic neurons from human embryonic stem cells
ZA200401646B (en) * 2003-03-12 2004-06-07 Reliance Life Sciences Pvt Ltd Derivation of terminally differentiated dopaminergic neurons from human embryonic stem cells.
WO2010008486A2 (en) * 2008-06-24 2010-01-21 Parkinsons Institute Pluripotent cell lines and methods of use thereof

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JP2013520960A (ja) 2013-06-10
US20130034858A1 (en) 2013-02-07
US9097727B2 (en) 2015-08-04

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