JP5841952B2 - 腫瘍性疾患の治療的処置にて用いるための成体幹細胞由来の微細小胞（ｍｖ） - Google Patents
腫瘍性疾患の治療的処置にて用いるための成体幹細胞由来の微細小胞（ｍｖ） Download PDFInfo
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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| EP10425052A EP2363136A1 (en) | 2010-03-02 | 2010-03-02 | Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease |
| EP10425052.7 | 2010-03-02 | ||
| PCT/EP2011/052945 WO2011107437A1 (en) | 2010-03-02 | 2011-02-28 | Microvesicles (mvs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease |
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| JP2013520971A JP2013520971A (ja) | 2013-06-10 |
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| PT (1) | PT2542250E (enExample) |
| WO (1) | WO2011107437A1 (enExample) |
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| EP2363136A1 (en) * | 2010-03-02 | 2011-09-07 | Fresenius Medical Care Deutschland GmbH | Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease |
| EP2569418B1 (en) | 2010-05-12 | 2016-11-02 | RegenMed (Cayman) Ltd. | Bioactive renal cells |
| ITRM20110403A1 (it) * | 2011-07-28 | 2013-01-29 | Ospedale Pediatrico Bambino Gesu | Microvescicole isolate da cellule mesenchimali come agenti immunosoppressori. |
| CN102357071B (zh) * | 2011-10-26 | 2013-10-23 | 重庆医科大学附属儿童医院 | 载紫杉醇纳米微泡及其制备方法 |
| KR102108245B1 (ko) * | 2011-11-30 | 2020-05-08 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | 중간엽 간질 세포 및 이에 관련된 용도 |
| US8961956B2 (en) | 2011-11-30 | 2015-02-24 | Ocata Therapeutics, Inc. | Mesenchymal stromal cells and uses related thereto |
| US11286463B2 (en) | 2012-03-08 | 2022-03-29 | Advanced ReGen Medical Technologies, LLC | Reprogramming of aged adult stem cells |
| CN104471059B (zh) | 2012-07-12 | 2018-04-17 | 珠海横琴爱姆斯坦生物科技有限公司 | 人胚胎干细胞衍生的间充质样干细胞、方法及其应用 |
| WO2015095794A1 (en) | 2013-12-20 | 2015-06-25 | Advanced ReGen Medical Technologies, LLC | Compositions for cellular restoration and methods of making and using same |
| US10772911B2 (en) | 2013-12-20 | 2020-09-15 | Advanced ReGen Medical Technologies, LLC | Cell free compositions for cellular restoration and methods of making and using same |
| EP4445915A3 (en) * | 2014-03-24 | 2025-01-22 | Advanced Regen Medical Technologies, LLC | Cell free compositions for cellular restoration and methods of making and using same |
| WO2015179301A1 (en) * | 2014-05-19 | 2015-11-26 | Eleftherios Papoutsakis | Megakaryocytic particles and microparticles for cell therapy & fate modification of stem and progenitor cells |
| WO2017190000A1 (en) | 2016-04-29 | 2017-11-02 | Advanced ReGen Medical Technologies, LLC | Microrna compositions and methods of making and using same |
| JP7372917B2 (ja) * | 2017-12-14 | 2023-11-01 | ユニシテ エーファウ アクチェンゲゼルシャフト | ｍｉＲＮＡを含有する、腎癌の処置における使用のための薬学的キャリア |
| EP3740576A4 (en) | 2018-01-18 | 2021-10-20 | Advanced Regen Medical Technologies, LLC | THERAPEUTIC COMPOSITIONS AND THEIR PREPARATION AND USE METHODS |
| WO2019197442A1 (en) * | 2018-04-12 | 2019-10-17 | Unicyte Ev Ag | A combination of active ingredients for the treatment of tumor |
| CN111494417B (zh) * | 2020-02-10 | 2024-04-09 | 寇晓星 | 诱导性细胞外囊泡在制备治疗肿瘤药物中的应用 |
| CA3178268A1 (en) | 2020-05-11 | 2021-11-18 | Jonathan Thon | Compositions and methods related to megakaryocyte-derived extracellular vesicles |
| KR102601831B1 (ko) * | 2020-09-23 | 2023-11-14 | 대한민국 | 고형암 증식 억제 효과를 갖는 개과동물의 엑소좀 |
| EP4534649A1 (en) * | 2023-10-03 | 2025-04-09 | Unicyte AG | A method of qualifying as pharmaceutically active a batch of undifferentiated adult stem cells having the potential to differentiate along the hepatic lineage |
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| US6088613A (en) * | 1989-12-22 | 2000-07-11 | Imarx Pharmaceutical Corp. | Method of magnetic resonance focused surgical and therapeutic ultrasound |
| JP2001511775A (ja) * | 1997-01-30 | 2001-08-14 | クワッドラント・ヘルスケア・（ユーケイ）・リミテッド | 微粒子および癌処置での使用 |
| NZ506051A (en) * | 1998-02-09 | 2003-08-29 | Bracco Res S | Targeted delivery of biologically active media |
| US20020177551A1 (en) * | 2000-05-31 | 2002-11-28 | Terman David S. | Compositions and methods for treatment of neoplastic disease |
| US7128903B2 (en) * | 2001-10-03 | 2006-10-31 | Innovative Pharmaceutical Concepts (Ipc) Inc. | Pharmaceutical preparations useful for treating tumors and lesions of the skin and the mucous membranes and methods and kits using same |
| EP1766053A4 (en) * | 2004-06-02 | 2007-12-12 | Sourcepharm Inc | MICROVESICLES CONTAINING RNA AND METHODS |
| US8148335B2 (en) * | 2004-06-23 | 2012-04-03 | Children's Hospital & Research Center Oakland | De-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy |
| GB0501129D0 (en) * | 2005-01-19 | 2005-02-23 | Ribostem Ltd | Method of treatment by administration of RNA |
| WO2006126219A1 (en) | 2005-05-26 | 2006-11-30 | Fresenius Medical Care Deutschland G.M.B.H. | Liver progenitor cells |
| TWI479559B (zh) | 2007-06-28 | 2015-04-01 | Quantum Global Tech Llc | 以選擇性噴灑蝕刻來清潔腔室部件的方法和設備 |
| US8455199B2 (en) * | 2007-09-14 | 2013-06-04 | The Ohio State University Research Foundation | MicroRNA expression in human peripheral blood microvesicles and uses thereof |
| JP5719171B2 (ja) * | 2007-10-15 | 2015-05-13 | フレゼニウス メディカル ケア ドイッチェランド ゲゼルシャフト ミット ベシュレンクテル ハフツング | 内皮細胞移植、特に膵島移植による糖尿病の処置におけるアジュバント活性を有する医薬を調製するための微小胞（ｍｖ）の使用、および関連方法 |
| EP2604271B1 (en) * | 2007-10-29 | 2014-09-17 | Fresenius Medical Care Deutschland GmbH | A stem cell-derived microvesicle (MV) for use in inhibiting apoptosis induced by a cytostatic agent |
| AU2009203638C1 (en) * | 2008-01-04 | 2013-07-25 | Lydac Neuroscience Limited | Microvesicles |
| US20110003008A1 (en) * | 2008-02-22 | 2011-01-06 | Agency For Science, Technology And Research (A*Star) | Mesenchymal stem cell particles |
| EP2186883A1 (en) | 2008-11-04 | 2010-05-19 | Fresenius Medical Care | An isolated multipotent mesenchymal stem cell from human adult glomeruli (hGL-MSC), a method of preparing thereof and uses thereof in the regenerative medicine of the kidney |
| EP2363136A1 (en) * | 2010-03-02 | 2011-09-07 | Fresenius Medical Care Deutschland GmbH | Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease |
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2010
- 2010-03-02 EP EP10425052A patent/EP2363136A1/en not_active Withdrawn
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2011
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- 2011-02-28 ES ES11705585.5T patent/ES2554492T3/es active Active
- 2011-02-28 CN CN201180011925.0A patent/CN102781454B/zh active Active
- 2011-02-28 HU HUE11705585A patent/HUE026292T2/en unknown
- 2011-02-28 PT PT117055855T patent/PT2542250E/pt unknown
- 2011-02-28 WO PCT/EP2011/052945 patent/WO2011107437A1/en not_active Ceased
- 2011-02-28 DK DK11705585.5T patent/DK2542250T3/en active
- 2011-02-28 EP EP11705585.5A patent/EP2542250B1/en active Active
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2017
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2023
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Also Published As
| Publication number | Publication date |
|---|---|
| EP2542250B1 (en) | 2015-08-26 |
| JP2013520971A (ja) | 2013-06-10 |
| EP2363136A1 (en) | 2011-09-07 |
| HUE026292T2 (en) | 2016-05-30 |
| US20170348356A1 (en) | 2017-12-07 |
| DK2542250T3 (en) | 2015-12-07 |
| PL2542250T3 (pl) | 2016-04-29 |
| CN102781454B (zh) | 2015-12-16 |
| ES2554492T3 (es) | 2015-12-21 |
| US20190060369A1 (en) | 2019-02-28 |
| CN102781454A (zh) | 2012-11-14 |
| US20230248774A1 (en) | 2023-08-10 |
| PT2542250E (pt) | 2015-12-09 |
| EP2542250A1 (en) | 2013-01-09 |
| US9717760B2 (en) | 2017-08-01 |
| US10105395B2 (en) | 2018-10-23 |
| WO2011107437A1 (en) | 2011-09-09 |
| US20120321723A1 (en) | 2012-12-20 |
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