PT2542250E - Microvesículas (mvs) derivadas de células estaminais adultas para uso no tratamento terapêutico de uma doença tumoral - Google Patents

Microvesículas (mvs) derivadas de células estaminais adultas para uso no tratamento terapêutico de uma doença tumoral Download PDF

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Publication number
PT2542250E
PT2542250E PT117055855T PT11705585T PT2542250E PT 2542250 E PT2542250 E PT 2542250E PT 117055855 T PT117055855 T PT 117055855T PT 11705585 T PT11705585 T PT 11705585T PT 2542250 E PT2542250 E PT 2542250E
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PT
Portugal
Prior art keywords
microvesicles
mvs
derived
stem cells
therapeutic treatment
Prior art date
Application number
PT117055855T
Other languages
English (en)
Portuguese (pt)
Inventor
Stefania Bruno
Maria Beatriz Herrera Sanchez
Valentina Fonsato
Giovanni Camussi
Ciro Tetta
Original Assignee
Fresenius Medical Care De Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fresenius Medical Care De Gmbh filed Critical Fresenius Medical Care De Gmbh
Publication of PT2542250E publication Critical patent/PT2542250E/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PT117055855T 2010-03-02 2011-02-28 Microvesículas (mvs) derivadas de células estaminais adultas para uso no tratamento terapêutico de uma doença tumoral PT2542250E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP10425052A EP2363136A1 (en) 2010-03-02 2010-03-02 Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease

Publications (1)

Publication Number Publication Date
PT2542250E true PT2542250E (pt) 2015-12-09

Family

ID=42306621

Family Applications (1)

Application Number Title Priority Date Filing Date
PT117055855T PT2542250E (pt) 2010-03-02 2011-02-28 Microvesículas (mvs) derivadas de células estaminais adultas para uso no tratamento terapêutico de uma doença tumoral

Country Status (10)

Country Link
US (4) US9717760B2 (enExample)
EP (2) EP2363136A1 (enExample)
JP (1) JP5841952B2 (enExample)
CN (1) CN102781454B (enExample)
DK (1) DK2542250T3 (enExample)
ES (1) ES2554492T3 (enExample)
HU (1) HUE026292T2 (enExample)
PL (1) PL2542250T3 (enExample)
PT (1) PT2542250E (enExample)
WO (1) WO2011107437A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2363136A1 (en) * 2010-03-02 2011-09-07 Fresenius Medical Care Deutschland GmbH Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease
EP2569418B1 (en) 2010-05-12 2016-11-02 RegenMed (Cayman) Ltd. Bioactive renal cells
ITRM20110403A1 (it) * 2011-07-28 2013-01-29 Ospedale Pediatrico Bambino Gesu Microvescicole isolate da cellule mesenchimali come agenti immunosoppressori.
CN102357071B (zh) * 2011-10-26 2013-10-23 重庆医科大学附属儿童医院 载紫杉醇纳米微泡及其制备方法
KR102108245B1 (ko) * 2011-11-30 2020-05-08 아스텔라스 인스티튜트 포 리제너러티브 메디슨 중간엽 간질 세포 및 이에 관련된 용도
US8961956B2 (en) 2011-11-30 2015-02-24 Ocata Therapeutics, Inc. Mesenchymal stromal cells and uses related thereto
US11286463B2 (en) 2012-03-08 2022-03-29 Advanced ReGen Medical Technologies, LLC Reprogramming of aged adult stem cells
CN104471059B (zh) 2012-07-12 2018-04-17 珠海横琴爱姆斯坦生物科技有限公司 人胚胎干细胞衍生的间充质样干细胞、方法及其应用
WO2015095794A1 (en) 2013-12-20 2015-06-25 Advanced ReGen Medical Technologies, LLC Compositions for cellular restoration and methods of making and using same
US10772911B2 (en) 2013-12-20 2020-09-15 Advanced ReGen Medical Technologies, LLC Cell free compositions for cellular restoration and methods of making and using same
EP4445915A3 (en) * 2014-03-24 2025-01-22 Advanced Regen Medical Technologies, LLC Cell free compositions for cellular restoration and methods of making and using same
WO2015179301A1 (en) * 2014-05-19 2015-11-26 Eleftherios Papoutsakis Megakaryocytic particles and microparticles for cell therapy & fate modification of stem and progenitor cells
WO2017190000A1 (en) 2016-04-29 2017-11-02 Advanced ReGen Medical Technologies, LLC Microrna compositions and methods of making and using same
JP7372917B2 (ja) * 2017-12-14 2023-11-01 ユニシテ エーファウ アクチェンゲゼルシャフト ｍｉＲＮＡを含有する、腎癌の処置における使用のための薬学的キャリア
EP3740576A4 (en) 2018-01-18 2021-10-20 Advanced Regen Medical Technologies, LLC THERAPEUTIC COMPOSITIONS AND THEIR PREPARATION AND USE METHODS
WO2019197442A1 (en) * 2018-04-12 2019-10-17 Unicyte Ev Ag A combination of active ingredients for the treatment of tumor
CN111494417B (zh) * 2020-02-10 2024-04-09 寇晓星 诱导性细胞外囊泡在制备治疗肿瘤药物中的应用
CA3178268A1 (en) 2020-05-11 2021-11-18 Jonathan Thon Compositions and methods related to megakaryocyte-derived extracellular vesicles
KR102601831B1 (ko) * 2020-09-23 2023-11-14 대한민국 고형암 증식 억제 효과를 갖는 개과동물의 엑소좀
EP4534649A1 (en) * 2023-10-03 2025-04-09 Unicyte AG A method of qualifying as pharmaceutically active a batch of undifferentiated adult stem cells having the potential to differentiate along the hepatic lineage

Family Cites Families (17)

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US6088613A (en) * 1989-12-22 2000-07-11 Imarx Pharmaceutical Corp. Method of magnetic resonance focused surgical and therapeutic ultrasound
JP2001511775A (ja) * 1997-01-30 2001-08-14 クワッドラント・ヘルスケア・（ユーケイ）・リミテッド 微粒子および癌処置での使用
NZ506051A (en) * 1998-02-09 2003-08-29 Bracco Res S Targeted delivery of biologically active media
US20020177551A1 (en) * 2000-05-31 2002-11-28 Terman David S. Compositions and methods for treatment of neoplastic disease
US7128903B2 (en) * 2001-10-03 2006-10-31 Innovative Pharmaceutical Concepts (Ipc) Inc. Pharmaceutical preparations useful for treating tumors and lesions of the skin and the mucous membranes and methods and kits using same
EP1766053A4 (en) * 2004-06-02 2007-12-12 Sourcepharm Inc MICROVESICLES CONTAINING RNA AND METHODS
US8148335B2 (en) * 2004-06-23 2012-04-03 Children's Hospital & Research Center Oakland De-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy
GB0501129D0 (en) * 2005-01-19 2005-02-23 Ribostem Ltd Method of treatment by administration of RNA
WO2006126219A1 (en) 2005-05-26 2006-11-30 Fresenius Medical Care Deutschland G.M.B.H. Liver progenitor cells
TWI479559B (zh) 2007-06-28 2015-04-01 Quantum Global Tech Llc 以選擇性噴灑蝕刻來清潔腔室部件的方法和設備
US8455199B2 (en) * 2007-09-14 2013-06-04 The Ohio State University Research Foundation MicroRNA expression in human peripheral blood microvesicles and uses thereof
JP5719171B2 (ja) * 2007-10-15 2015-05-13 フレゼニウス メディカル ケア ドイッチェランド ゲゼルシャフト ミット ベシュレンクテル ハフツング 内皮細胞移植、特に膵島移植による糖尿病の処置におけるアジュバント活性を有する医薬を調製するための微小胞（ｍｖ）の使用、および関連方法
EP2604271B1 (en) * 2007-10-29 2014-09-17 Fresenius Medical Care Deutschland GmbH A stem cell-derived microvesicle (MV) for use in inhibiting apoptosis induced by a cytostatic agent
AU2009203638C1 (en) * 2008-01-04 2013-07-25 Lydac Neuroscience Limited Microvesicles
US20110003008A1 (en) * 2008-02-22 2011-01-06 Agency For Science, Technology And Research (A*Star) Mesenchymal stem cell particles
EP2186883A1 (en) 2008-11-04 2010-05-19 Fresenius Medical Care An isolated multipotent mesenchymal stem cell from human adult glomeruli (hGL-MSC), a method of preparing thereof and uses thereof in the regenerative medicine of the kidney
EP2363136A1 (en) * 2010-03-02 2011-09-07 Fresenius Medical Care Deutschland GmbH Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease

Also Published As

Publication number Publication date
EP2542250B1 (en) 2015-08-26
JP2013520971A (ja) 2013-06-10
EP2363136A1 (en) 2011-09-07
JP5841952B2 (ja) 2016-01-13
HUE026292T2 (en) 2016-05-30
US20170348356A1 (en) 2017-12-07
DK2542250T3 (en) 2015-12-07
PL2542250T3 (pl) 2016-04-29
CN102781454B (zh) 2015-12-16
ES2554492T3 (es) 2015-12-21
US20190060369A1 (en) 2019-02-28
CN102781454A (zh) 2012-11-14
US20230248774A1 (en) 2023-08-10
EP2542250A1 (en) 2013-01-09
US9717760B2 (en) 2017-08-01
US10105395B2 (en) 2018-10-23
WO2011107437A1 (en) 2011-09-09
US20120321723A1 (en) 2012-12-20

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