JP5837622B2 - 多胎妊娠の分子検査 - Google Patents

多胎妊娠の分子検査 Download PDF

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JP5837622B2
JP5837622B2 JP2013554948A JP2013554948A JP5837622B2 JP 5837622 B2 JP5837622 B2 JP 5837622B2 JP 2013554948 A JP2013554948 A JP 2013554948A JP 2013554948 A JP2013554948 A JP 2013554948A JP 5837622 B2 JP5837622 B2 JP 5837622B2
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allele
locus
fetuses
fetal
loci
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JP2014507158A5 (enExample
JP2014507158A (ja
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ミン デニス ロー ユク
ミン デニス ロー ユク
クン ロッサ チウ ワイ
クン ロッサ チウ ワイ
クワン チェー チャン
クワン チェー チャン
タク ユン ルン
タク ユン ルン
ペイヨン チャン
ペイヨン チャン
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Chinese University of Hong Kong CUHK
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    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
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    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
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    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
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    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
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    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/30—Unsupervised data analysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/40—Population genetics; Linkage disequilibrium

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JP2013554948A 2011-02-24 2012-02-24 多胎妊娠の分子検査 Active JP5837622B2 (ja)

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Application Number Priority Date Filing Date Title
US201161446256P 2011-02-24 2011-02-24
US61/446,256 2011-02-24
PCT/IB2012/000344 WO2013041921A1 (en) 2011-02-24 2012-02-24 Molecular testing of multiple pregnancies

Related Child Applications (1)

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JP2014507158A JP2014507158A (ja) 2014-03-27
JP2014507158A5 JP2014507158A5 (enExample) 2014-05-08
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US (2) US10900080B2 (enExample)
EP (5) EP2678451B1 (enExample)
JP (2) JP5837622B2 (enExample)
CN (2) CN103492589B (enExample)
AU (1) AU2012311262C1 (enExample)
CA (3) CA3252077A1 (enExample)
TW (1) TWI611186B (enExample)
WO (1) WO2013041921A1 (enExample)

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US11322224B2 (en) 2010-05-18 2022-05-03 Natera, Inc. Methods for non-invasive prenatal ploidy calling
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US10482994B2 (en) 2012-10-04 2019-11-19 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
TWI489305B (zh) * 2012-11-21 2015-06-21 Bgi Diagnosis Co Ltd 對胎兒遺傳異常的無創性檢測
EA202190075A3 (ru) * 2013-02-28 2021-07-30 Те Чайниз Юниверсити Ов Гонконг Анализ транскриптома материнской плазмы с применением массивного параллельного секвенирования рнк
AU2014231358A1 (en) 2013-03-15 2015-09-24 The Chinese University Of Hong Kong Determining fetal genomes for multiple fetus pregnancies
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US12492429B2 (en) 2014-04-21 2025-12-09 Natera, Inc. Detecting mutations and ploidy in chromosomal segments
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US20180173846A1 (en) 2014-06-05 2018-06-21 Natera, Inc. Systems and Methods for Detection of Aneuploidy
EP3739061B1 (en) * 2015-07-20 2022-03-23 The Chinese University Of Hong Kong Methylation pattern analysis of haplotypes in tissues in dna mixture
WO2018064486A1 (en) 2016-09-29 2018-04-05 Counsyl, Inc. Noninvasive prenatal screening using dynamic iterative depth optimization
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WO2018223053A1 (en) 2017-06-02 2018-12-06 Affymetrix, Inc. Array-based methods for analysing mixed samples using differently labelled allele-specific probes
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EP3642744B1 (en) * 2017-06-20 2025-02-26 Illumina, Inc. Methods for accurate computational decomposition of dna mixtures from contributors of unknown genotypes
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US12234509B2 (en) 2018-07-03 2025-02-25 Natera, Inc. Methods for detection of donor-derived cell-free DNA
CN112634986B (zh) * 2019-09-24 2024-07-26 厦门赛尔吉亚医学检验所有限公司 一种基于孕妇外周血对双胞胎合子性质的无创鉴定方法
KR102162831B1 (ko) 2019-12-26 2020-10-08 주식회사 마크로젠 혼합 모델을 이용한 쌍태아의 접합성 타입 결정 방법 및 분석 장치
US20230227897A1 (en) * 2020-12-16 2023-07-20 Seedna Inc. Method for calculating the fidelity of the signal of polymorphic genetic loci
CN114214425B (zh) * 2020-12-23 2024-01-19 上海亿康医学检验所有限公司 一种鉴定核酸样本的亲本倾向性的方法或装置
CN113981062B (zh) * 2021-10-14 2024-02-20 武汉蓝沙医学检验实验室有限公司 以非生父和母亲dna评估胎儿dna浓度的方法及应用
WO2023120783A1 (ko) * 2021-12-24 2023-06-29 주식회사 마크로젠 혼합 모델을 이용한 쌍태아의 접합성 타입 결정 방법 및 분석 장치
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CN106011237B (zh) 2019-12-13
EP3202921A1 (en) 2017-08-09
EP2678451A1 (en) 2014-01-01
CA3160848A1 (en) 2013-03-28
EP2860265A1 (en) 2015-04-15
US20210095340A1 (en) 2021-04-01
CA3160848C (en) 2025-07-08
CN103492589B (zh) 2016-06-15
CA2827873C (en) 2022-08-16
JP6068598B2 (ja) 2017-01-25
EP2860265B1 (en) 2016-10-26
AU2012311262C1 (en) 2017-06-29
US10900080B2 (en) 2021-01-26
EP3202921B1 (en) 2019-02-13
JP2016034282A (ja) 2016-03-17
HK1203567A1 (en) 2015-10-30
EP3489368B1 (en) 2020-09-09
CN106011237A (zh) 2016-10-12
AU2012311262A1 (en) 2013-05-02
EP2682887A2 (en) 2014-01-08
WO2013041921A1 (en) 2013-03-28
JP2014507158A (ja) 2014-03-27
EP2678451A4 (en) 2014-10-22
CA3252077A1 (en) 2025-03-20
CN103492589A (zh) 2014-01-01
EP3489368A1 (en) 2019-05-29
US20130059733A1 (en) 2013-03-07
TWI611186B (zh) 2018-01-11
CA2827873A1 (en) 2013-03-28
AU2012311262B2 (en) 2014-10-09
EP2678451B1 (en) 2017-04-26
TW201243326A (en) 2012-11-01

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