JP5827220B2 - 人工多能性幹細胞の樹立効率改善方法 - Google Patents
人工多能性幹細胞の樹立効率改善方法 Download PDFInfo
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- JP5827220B2 JP5827220B2 JP2012513400A JP2012513400A JP5827220B2 JP 5827220 B2 JP5827220 B2 JP 5827220B2 JP 2012513400 A JP2012513400 A JP 2012513400A JP 2012513400 A JP2012513400 A JP 2012513400A JP 5827220 B2 JP5827220 B2 JP 5827220B2
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2501/605—Nanog
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/606—Transcription factors c-Myc
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/608—Lin28
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- Bioinformatics & Cheminformatics (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28232010P | 2010-01-22 | 2010-01-22 | |
| US61/282,320 | 2010-01-22 | ||
| PCT/JP2011/051685 WO2011090221A1 (en) | 2010-01-22 | 2011-01-21 | Method for improving induced pluripotent stem cell generation efficiency |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013517758A JP2013517758A (ja) | 2013-05-20 |
| JP2013517758A5 JP2013517758A5 (cg-RX-API-DMAC7.html) | 2014-03-06 |
| JP5827220B2 true JP5827220B2 (ja) | 2015-12-02 |
Family
ID=44307020
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012513400A Active JP5827220B2 (ja) | 2010-01-22 | 2011-01-21 | 人工多能性幹細胞の樹立効率改善方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9005967B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2526189B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5827220B2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2011090221A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20140063501A (ko) | 2010-12-22 | 2014-05-27 | 페이트 세러퓨틱스, 인코포레이티드 | 단세포 분류 및 iPSC의 증강된 재프로그래밍을 위한 세포 배양 플랫폼 |
| AU2014212230B2 (en) | 2013-02-01 | 2019-07-04 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Method for generating retinal pigment epithelium (RPE) cells from induced pluripotent stem cells (iPSCs) |
| EP2954046B1 (en) | 2013-02-06 | 2025-10-15 | University Of Rochester | Induced pluripotent cell-derived oligodendrocyte progenitor cells for the treatment of myelin disorders |
| ES2966757T3 (es) * | 2014-03-04 | 2024-04-24 | Fate Therapeutics Inc | Métodos de reprogramación mejorados y plataformas de cultivo celular |
| US9724432B2 (en) | 2015-04-30 | 2017-08-08 | University Of Rochester | Non-human mammal model of human degenerative disorder, uses thereof, and method of treating human degenerative disorder |
| AU2016321170B2 (en) | 2015-09-08 | 2022-09-01 | Fujifilm Cellular Dynamics | Method for reproducible differentiation of clinical-grade retinal pigment epithelium cells |
| EP3347457B1 (en) | 2015-09-08 | 2021-10-27 | FUJIFILM Cellular Dynamics, Inc. | Macs-based purification of stem cell-derived retinal pigment epithelium |
| SG10202111851YA (en) | 2015-10-16 | 2021-12-30 | Fate Therapeutics Inc | Platform for the Induction & Maintenance of Ground State Pluripotency |
| US10947502B2 (en) | 2015-10-20 | 2021-03-16 | FUJIFILM Cellular Dynamics, Inc. | Methods for directed differentiation of pluripotent stem cells to immune cells |
| CA3029582A1 (en) | 2016-07-01 | 2018-01-04 | Research Development Foundation | Elimination of proliferating cells from stem cell-derived grafts |
| US11866733B2 (en) | 2016-08-01 | 2024-01-09 | University of Pittsburgh—of the Commonwealth System of Higher Education | Human induced pluripotent stem cells for high efficiency genetic engineering |
| JP7248571B2 (ja) | 2016-10-05 | 2023-03-29 | フジフィルム セルラー ダイナミクス,インコーポレイテッド | MeCP2が破壊された誘導多能性幹細胞からの成熟系列の生成 |
| US11458225B2 (en) | 2016-11-09 | 2022-10-04 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | 3D vascularized human ocular tissue for cell therapy and drug discovery |
| US11530388B2 (en) | 2017-02-14 | 2022-12-20 | University of Pittsburgh—of the Commonwealth System of Higher Education | Methods of engineering human induced pluripotent stem cells to produce liver tissue |
| EP4083063A3 (en) | 2017-04-18 | 2023-01-04 | FUJIFILM Cellular Dynamics, Inc. | Antigen-specific immune effector cells |
| EP3621434A4 (en) | 2017-05-10 | 2021-03-31 | University of Rochester | METHOD OF TREATMENT OF NEUROPSYCHIATRIC DISORDERS |
| EP3781675A1 (en) | 2018-04-20 | 2021-02-24 | FUJIFILM Cellular Dynamics, Inc. | Method for differentiation of ocular cells and use thereof |
| EP3806861A1 (en) | 2018-06-18 | 2021-04-21 | University of Rochester | Methods of treating schizophrenia and other neuropsychiatric disorders |
| CA3103675A1 (en) | 2018-06-21 | 2019-12-26 | University Of Rochester | Methods of treating or inhibiting onset of huntington's disease |
| WO2020009714A1 (en) * | 2018-07-02 | 2020-01-09 | Lin Shi Lung | In-Vitro Induction of Adult Stem Cell Expansion and Derivation |
| CN113226387B (zh) | 2018-11-19 | 2024-02-23 | 美国政府(由卫生和人类服务部的部长所代表) | 可生物降解的组织置换植入物及其用途 |
| AU2019386140A1 (en) | 2018-11-28 | 2021-06-24 | Board Of Regents, The University Of Texas System | Multiplex genome editing of immune cells to enhance functionality and resistance to suppressive environment |
| MX2021006393A (es) | 2018-11-29 | 2021-10-13 | Univ Texas | Metodos para expansion ex vivo de celulas exterminadoras naturales y uso de las mismas. |
| EP3894556A1 (en) | 2018-12-11 | 2021-10-20 | University of Rochester | Methods of treating schizophrenia and other neuropsychiatric disorders |
| WO2020167822A2 (en) | 2019-02-13 | 2020-08-20 | University Of Rochester | Gene networks that mediate remyelination of the human brain |
| AU2021235185A1 (en) | 2020-03-09 | 2022-11-03 | Fujifilm Corporation | Markers specific for pluripotent stem cells, and methods of using the same |
| PH12022553083A1 (en) | 2020-05-29 | 2024-03-25 | Fujifilm Cellular Dynamics Inc | Bilayer of retinal pigmented epithelium and photoreceptors and use thereof |
| WO2021243256A1 (en) | 2020-05-29 | 2021-12-02 | FUJIFILM Cellular Dynamics, Inc. | Retinal pigmented epithelium and photoreceptor dual cell aggregates and methods of use thereof |
| WO2022104109A1 (en) | 2020-11-13 | 2022-05-19 | Catamaran Bio, Inc. | Genetically modified natural killer cells and methods of use thereof |
| JP2023550453A (ja) | 2020-11-18 | 2023-12-01 | 富士フイルム株式会社 | セクレトーム含有組成物の生成、並びにその使用及び分析方法 |
| KR20230113768A (ko) | 2020-11-24 | 2023-08-01 | 모나쉬 유니버시티 | 유도 줄기 세포 |
| JP2023550181A (ja) | 2020-11-24 | 2023-11-30 | モナシュ ユニバーシティ | 方法及び細胞構造体 |
| US20220162288A1 (en) | 2020-11-25 | 2022-05-26 | Catamaran Bio, Inc. | Cellular therapeutics engineered with signal modulators and methods of use thereof |
| CA3214490A1 (en) | 2021-03-25 | 2022-09-29 | Bluerock Therapeutics Lp | Methods for obtaining induced pluripotent stem cells |
| KR20240011831A (ko) | 2021-05-26 | 2024-01-26 | 후지필름 셀룰러 다이내믹스, 인코포레이티드 | 만능 줄기 세포에서 유전자의 신속한 사일런싱을 방지하기 위한 방법 |
| AU2022280062A1 (en) | 2021-05-28 | 2023-11-30 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods to generate macular, central and peripheral retinal pigment epithelial cells |
| CA3220433A1 (en) | 2021-05-28 | 2022-12-01 | Arvydas Maminishkis | Biodegradable tissue scaffold with secondary matrix to host weakly adherent cells |
| KR20240056604A (ko) | 2021-09-13 | 2024-04-30 | 후지필름 셀룰러 다이내믹스, 인코포레이티드 | 수임 심장 전구세포의 제조 방법 |
| WO2023069843A1 (en) | 2021-10-20 | 2023-04-27 | University Of Rochester | Humanized chimeras for the prospective assessment of cell addition and replacement therapies |
| AU2022368907A1 (en) | 2021-10-20 | 2024-05-02 | University Of Copenhagen | Rejuvenation treatment of age-related white matter loss |
| JP2024539140A (ja) | 2021-10-20 | 2024-10-28 | ユニヴァーシティ オヴ ロチェスター | グリア前駆細胞を若返らせるための方法及び若返ったグリア前駆細胞それ自体 |
| JP2024542015A (ja) | 2021-11-02 | 2024-11-13 | ユニバーシティ オブ ロチェスター | 脳内でのtcf7l2媒介性髄鞘再生 |
| WO2023150557A1 (en) | 2022-02-01 | 2023-08-10 | University Of Rochester | Methods of generating a population of neurons from human glial progenitor cells and genetic constructs for carrying out such methods |
| WO2023172514A1 (en) | 2022-03-07 | 2023-09-14 | Catamaran Bio, Inc. | Engineered immune cell therapeutics targeted to her2 and methods of use thereof |
| EP4518876A1 (en) | 2022-05-05 | 2025-03-12 | University of Rochester | Dual macroglial-microglial approach towards therapeutic cell replacement in neurodegenerative and neuropsychiatric disease |
| WO2024006911A1 (en) | 2022-06-29 | 2024-01-04 | FUJIFILM Holdings America Corporation | Ipsc-derived astrocytes and methods of use thereof |
| JP2025532957A (ja) | 2022-09-30 | 2025-10-03 | フジフィルム セルラー ダイナミクス,インコーポレイテッド | 心臓線維芽細胞の作製方法 |
| EP4658294A2 (en) | 2023-02-02 | 2025-12-10 | University of Rochester | Competitive replacement of glial cells |
| WO2024192329A1 (en) | 2023-03-16 | 2024-09-19 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods for producing stable human chondroctyes and their use for promoting cartillage growth and repair |
| WO2025245202A1 (en) | 2024-05-21 | 2025-11-27 | FUJIFILM Cellular Dynamics, Inc. | Particle counting and biomass measurements of aggregated cell compositions |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4937190A (en) | 1987-10-15 | 1990-06-26 | Wisconsin Alumni Research Foundation | Translation enhancer |
| DK1084230T3 (da) | 1998-06-08 | 2008-03-03 | Osiris Therapeutics Inc | Regulering af hæmatopoietisk stamcelledifferentiering ved anvendelse af humane mesenkymstamceller |
| CA2368948C (en) | 1999-05-18 | 2013-12-24 | Dnavec Research Inc. | Envelope gene-deficient virus vector of paramyxoviridae |
| US6602711B1 (en) | 2000-02-21 | 2003-08-05 | Wisconsin Alumni Research Foundation | Method of making embryoid bodies from primate embryonic stem cells |
| JP3660601B2 (ja) | 2001-03-30 | 2005-06-15 | 独立行政法人科学技術振興機構 | 胚性幹細胞からの神経幹細胞、運動ニューロン及びgaba作動性ニューロンの製造法 |
| JP2004121165A (ja) | 2002-10-07 | 2004-04-22 | Asahi Kasei Corp | 膵幹様細胞の分化誘導方法 |
| AU2006325975B2 (en) | 2005-12-13 | 2011-12-08 | Kyoto University | Nuclear reprogramming factor |
| US20090227032A1 (en) | 2005-12-13 | 2009-09-10 | Kyoto University | Nuclear reprogramming factor and induced pluripotent stem cells |
| DK3399025T3 (da) | 2007-03-23 | 2025-06-16 | Wisconsin Alumni Res Found | Omprogrammering af somatiske celler |
| CA2660123C (en) | 2007-10-31 | 2017-05-09 | Kyoto University | Nuclear reprogramming method |
-
2011
- 2011-01-21 JP JP2012513400A patent/JP5827220B2/ja active Active
- 2011-01-21 EP EP11734826.8A patent/EP2526189B1/en active Active
- 2011-01-21 WO PCT/JP2011/051685 patent/WO2011090221A1/en not_active Ceased
- 2011-01-21 US US13/497,044 patent/US9005967B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2526189A4 (en) | 2014-03-19 |
| WO2011090221A1 (en) | 2011-07-28 |
| EP2526189A1 (en) | 2012-11-28 |
| US9005967B2 (en) | 2015-04-14 |
| JP2013517758A (ja) | 2013-05-20 |
| EP2526189B1 (en) | 2016-10-12 |
| US20120276636A1 (en) | 2012-11-01 |
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