JP5816138B2 - 歯のホワイトニング組成物及び方法 - Google Patents
歯のホワイトニング組成物及び方法 Download PDFInfo
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- JP5816138B2 JP5816138B2 JP2012139830A JP2012139830A JP5816138B2 JP 5816138 B2 JP5816138 B2 JP 5816138B2 JP 2012139830 A JP2012139830 A JP 2012139830A JP 2012139830 A JP2012139830 A JP 2012139830A JP 5816138 B2 JP5816138 B2 JP 5816138B2
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/22—Peroxides; Oxygen; Ozone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/42—Colour properties
- A61K2800/43—Pigments; Dyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/42—Colour properties
- A61K2800/43—Pigments; Dyes
- A61K2800/434—Luminescent, Fluorescent; Optical brighteners; Photosensitizers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/81—Preparation or application process involves irradiation
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Inorganic Chemistry (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Detergent Compositions (AREA)
- Dental Preparations (AREA)
Description
約0.4ミクロン)のヒュームドシリカは、過酸化水素の効率的な分散及び酸化組成物内の光エネルギーの反射をもたらすことができる。
4mgのエオシンB、1mgのエリスロシンB、450mgのヒュームドシリカ、及び45mgの過ホウ素酸ナトリウムを混合することによって、プレミックスを調製した。これとは別に、50%過酸化水素溶液のpHを、酢酸ナトリウム溶液を用いてpH6に調製した。次に、約4〜6mlの調製した過酸化水素溶液をプラスチックの混合チャンバー内でプレミックスに添加し、直ちに使用した。
(比較の例2:組成物のホワイトニング効果)
10人のボランティアにおいて、本発明の典型的な組成物と、ローダミンB及び過酸化水素を含む組成物であるSMARTBLEACHのレーザーによる歯のホワイトニングシステムとの比較調査を行った。各患者の歯のシェードをホワイトニング組成物の塗布前に記録した。
(比較の例3:化学作用を持つ光の供給源の効果)
28人のボランティアについて、例1の組成物によるホワイトニングにおける化学作用を持つ光の異なる供給源の効果を比較する調査を行った。漂白セッションの3〜4日前に、予防的なセッションを各患者にて行った。各患者の歯のシェードを、ホワイトニング組成物の塗布前に記録した。
Claims (17)
- 過酸化水素、カルバミドペルオキシド、アルカリ金属ペルオキシド、ペルオキシ酸、及びペルオキシ酢酸からなる群より選択される酸化剤と、
400nm〜570nmのピーク吸収波長及び放射波長を有し、かつ、酸化剤の分解を活性化することができる蛍光色素を含む活性化剤とを含む組成物であって、
該組成物は、透明又は半透明のゲルである、歯のホワイトニング組成物。 - 前記組成物が、さらにラジカルの発生を促進可能な促進剤を含む、請求項1記載の組成物。
- 前記促進剤が、過ホウ酸ナトリウムを含む請求項2に記載の組成物。
- 前記組成物が、さらに酸化剤を安定化させることができる安定化剤を含む、請求項1から3のいずれか1項に記載の組成物。
- 前記安定化剤が、抗酸化剤、金属キレート剤、又は、pH調整剤である、請求項4に記載の組成物。
- 前記安定化剤が、酢酸ナトリウム、EDTA、亜硫酸ナトリウム、スズ塩、リン酸、及びスズのスルフォン酸塩からなる群より選択される、請求項4に記載の組成物。
- 前記組成物が、さらに増粘剤を含む、請求項1〜6のいずれか1項に記載の組成物。
- 前記増粘剤が、シリカ−アルミニウム酸化物、ヒュームドシリカ、カルボマー、トリエタノールアミン、ポリ(エチレンオキシド)、アミドスターチ及び二酸化ケイ素からなる群より選択される、請求項7に記載の組成物。
- 前記組成物が、さらに親水性ゲル化剤を含む、請求項1〜8のいずれか1項に記載の組成物。
- 前記組成物のpHが、5〜7である請求項1〜9のいずれか1項に記載の組成物。
- 前記組成物のpHが、4〜10である請求項1〜9のいずれか1項に記載の組成物。
- 化学光の照射下における酸化剤の光化学的活性化を促進するために使用される、請求項1〜11のいずれか1項に記載の組成物。
- 前記活性化剤が、435nm〜520nm又は520nm〜565nmの放射波長を有する、請求項1〜12のいずれか1項に記載の組成物。
- 過酸化水素、カルバミドペルオキシド、アルカリ金属ペルオキシド、ペルオキシ酸、及びペルオキシ酢酸からなる群より選択される酸化剤と、
400nm〜570nmのピーク吸収波長及び放射波長を有し、かつ、酸化剤の分解を活性化することができる蛍光色素を含む活性化剤とを含むキットであって、
前記酸化剤と前記活性化剤との組み合わせが、透明又は半透明のゲルである、歯のホワイトニングのためのキット。 - 2以上の成分を混合するための器具、塗布の案内、塗布のための器具、又は化学作用を持つ光の供給源をさらに備える請求項14に記載のキット。
- 少なくとも40%の光の透過を許容する請求項1〜13のいずれか1項に記載の組成物。
- 少なくとも70%の光の透過を許容する請求項1〜13のいずれか1項に記載の組成物。
Applications Claiming Priority (2)
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US73507205P | 2005-11-09 | 2005-11-09 | |
US60/735,072 | 2005-11-09 |
Related Parent Applications (1)
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JP2008539540A Division JP5366553B2 (ja) | 2005-11-09 | 2006-11-09 | 歯のホワイトニング組成物及び方法 |
Related Child Applications (1)
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JP2015151192A Division JP6290144B2 (ja) | 2005-11-09 | 2015-07-30 | 歯のホワイトニング組成物及び方法 |
Publications (2)
Publication Number | Publication Date |
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JP2012229229A JP2012229229A (ja) | 2012-11-22 |
JP5816138B2 true JP5816138B2 (ja) | 2015-11-18 |
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Family Applications (3)
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JP2008539540A Active JP5366553B2 (ja) | 2005-11-09 | 2006-11-09 | 歯のホワイトニング組成物及び方法 |
JP2012139830A Expired - Fee Related JP5816138B2 (ja) | 2005-11-09 | 2012-06-21 | 歯のホワイトニング組成物及び方法 |
JP2015151192A Expired - Fee Related JP6290144B2 (ja) | 2005-11-09 | 2015-07-30 | 歯のホワイトニング組成物及び方法 |
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JP2008539540A Active JP5366553B2 (ja) | 2005-11-09 | 2006-11-09 | 歯のホワイトニング組成物及び方法 |
Family Applications After (1)
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JP2015151192A Expired - Fee Related JP6290144B2 (ja) | 2005-11-09 | 2015-07-30 | 歯のホワイトニング組成物及び方法 |
Country Status (13)
Country | Link |
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US (6) | US8075875B2 (ja) |
EP (2) | EP2338465A1 (ja) |
JP (3) | JP5366553B2 (ja) |
CN (2) | CN103767886B (ja) |
AT (1) | ATE539733T1 (ja) |
BR (2) | BRPI0618475B1 (ja) |
CA (2) | CA2966261A1 (ja) |
CY (1) | CY1112578T1 (ja) |
ES (1) | ES2380239T3 (ja) |
HK (1) | HK1121068A1 (ja) |
PL (1) | PL1951184T3 (ja) |
PT (1) | PT1951184E (ja) |
WO (1) | WO2007080453A2 (ja) |
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