JP5808631B2 - 血管新生用足場、及び再生医療用の血管の製造方法 - Google Patents

血管新生用足場、及び再生医療用の血管の製造方法 Download PDF

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Publication number
JP5808631B2
JP5808631B2 JP2011215549A JP2011215549A JP5808631B2 JP 5808631 B2 JP5808631 B2 JP 5808631B2 JP 2011215549 A JP2011215549 A JP 2011215549A JP 2011215549 A JP2011215549 A JP 2011215549A JP 5808631 B2 JP5808631 B2 JP 5808631B2
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Prior art keywords
scaffold
vascular endothelial
angiogenesis
genetically modified
migration
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JP2011215549A
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Japanese (ja)
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JP2013074936A (ja
JP2013074936A5 (enExample
Inventor
玲子 岩澤
玲子 岩澤
中村　健太郎
中村　　健太郎
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Fujifilm Corp
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Fujifilm Corp
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Priority to JP2011215549A priority Critical patent/JP5808631B2/ja
Priority to US13/597,578 priority patent/US20130084638A1/en
Priority to EP12182347.0A priority patent/EP2578246B1/en
Publication of JP2013074936A publication Critical patent/JP2013074936A/ja
Publication of JP2013074936A5 publication Critical patent/JP2013074936A5/ja
Priority to US14/340,942 priority patent/US20140371145A1/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/222—Gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1825—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3808—Endothelial cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2011215549A 2011-09-29 2011-09-29 血管新生用足場、及び再生医療用の血管の製造方法 Active JP5808631B2 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2011215549A JP5808631B2 (ja) 2011-09-29 2011-09-29 血管新生用足場、及び再生医療用の血管の製造方法
US13/597,578 US20130084638A1 (en) 2011-09-29 2012-08-29 Scaffold for vascular endothelial cell migration
EP12182347.0A EP2578246B1 (en) 2011-09-29 2012-08-30 Scaffold for vascular endothelial cell migration
US14/340,942 US20140371145A1 (en) 2011-09-29 2014-07-25 Scaffold for vascular endothelial cell migration

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2011215549A JP5808631B2 (ja) 2011-09-29 2011-09-29 血管新生用足場、及び再生医療用の血管の製造方法

Publications (3)

Publication Number Publication Date
JP2013074936A JP2013074936A (ja) 2013-04-25
JP2013074936A5 JP2013074936A5 (enExample) 2014-01-30
JP5808631B2 true JP5808631B2 (ja) 2015-11-10

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JP2011215549A Active JP5808631B2 (ja) 2011-09-29 2011-09-29 血管新生用足場、及び再生医療用の血管の製造方法

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Country Link
US (2) US20130084638A1 (enExample)
EP (1) EP2578246B1 (enExample)
JP (1) JP5808631B2 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5876787B2 (ja) * 2011-08-31 2016-03-02 富士フイルム株式会社 細胞移植用細胞構造体および細胞移植用細胞集合体
JP6534269B2 (ja) * 2015-03-18 2019-06-26 富士フイルム株式会社 管状構造物、細胞構造体の製造方法、及び管状構造物の製造方法
EP3315509B1 (en) 2015-06-25 2021-02-17 Kola-Gen Pharma Inc. Polymerized peptide and gel having collagen-like structure
JPWO2017200039A1 (ja) * 2016-05-19 2019-03-22 富士フイルム株式会社 細胞培養方法、培地及び培地キット
EP3677289A4 (en) * 2017-08-30 2020-08-26 FUJIFILM Corporation ANGIOGENIC AGENT AND PROCESS FOR THE PRODUCTION OF THE LATTER
WO2019044990A1 (ja) 2017-08-30 2019-03-07 富士フイルム株式会社 細胞移植用デバイスおよびその製造方法
WO2019103981A1 (en) * 2017-11-22 2019-05-31 Geltor Inc. Methods and systems for engineering collagen
CN113444167B (zh) * 2021-07-15 2022-09-30 陕西巨子生物技术有限公司 重组人胶原蛋白多肽及其应用
AU2023317391A1 (en) 2022-08-04 2025-02-13 Integriculture Inc. Porous scaffold for cell culture and production method thereof
CN121100176A (zh) * 2023-05-15 2025-12-09 国立大学法人大阪大学 由生物体组织或器官制造高纯度血管内皮细胞群的方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6231881B1 (en) * 1992-02-24 2001-05-15 Anton-Lewis Usala Medium and matrix for long-term proliferation of cells
US6096710A (en) * 1995-11-17 2000-08-01 The Regents Of The University Of California Collagen-like peptoid residue-containing structures
DE69940802D1 (de) 1998-12-23 2009-06-10 Fujifilm Mfg Europe Bv Silberhalogenidemulsionen, die rekombinante gelatineartige Proteine enthalten
US6992172B1 (en) 1999-11-12 2006-01-31 Fibrogen, Inc. Recombinant gelatins
US6759386B2 (en) * 2000-04-06 2004-07-06 Wayne P. Franco Methods of use of fibroblast growth factor, vascular endothelial growth factor and related proteins in the treatment of acute and chronic heart disease
US7232802B2 (en) 2001-12-21 2007-06-19 Zimmer Orthobiologics, Inc. Compositions and methods for promoting myocardial and peripheral angiogenesis
US20040063206A1 (en) * 2002-09-30 2004-04-01 Rowley Jon A. Programmable scaffold and method for making and using the same
DE602004024834D1 (de) 2003-03-28 2010-02-04 Fuji Film Mfg Europ B V RGD-angereicherte, gelatine-ähnliche Proteine zur Verhinderung der Zelladhäsion
US20050002904A1 (en) * 2003-07-03 2005-01-06 Wary Kishore K. Uses of vascular endothelial growth factor and type I collagen inducible protein (VCIP)
JP2006083095A (ja) 2004-09-16 2006-03-30 Tohoku Univ 幹細胞および／または内皮前駆細胞の分化促進剤
US8198047B2 (en) 2007-02-21 2012-06-12 Fujifilm Manufacturing Europe B.V. RGD containing recombinant gelatin
WO2008133196A1 (ja) * 2007-04-19 2008-11-06 Fujifilm Corporation 再生医療用材料
WO2009072508A1 (ja) * 2007-12-03 2009-06-11 Fujifilm Corporation 体内埋め込み用の医療用組成物
JP5752033B2 (ja) * 2009-05-07 2015-07-22 富士フイルム株式会社 遺伝子組み換えゼラチンを含む血管新生誘導剤
WO2010147109A1 (ja) 2009-06-15 2010-12-23 富士フイルム株式会社 遺伝子組み換えゼラチン及び塩基性線維芽細胞増殖因子を含む血管新生誘導剤
KR20130005279A (ko) * 2010-03-01 2013-01-15 후지필름 가부시키가이샤 생체 친화성을 갖는 고분자 블록과 세포로 이루어지는 세포 구조체
EP2543398B1 (en) * 2010-03-02 2019-10-16 FUJIFILM Corporation Cell support and bone regeneration material

Also Published As

Publication number Publication date
US20140371145A1 (en) 2014-12-18
JP2013074936A (ja) 2013-04-25
US20130084638A1 (en) 2013-04-04
EP2578246A3 (en) 2015-01-14
EP2578246A2 (en) 2013-04-10
EP2578246B1 (en) 2016-06-01

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