JP5776111B2 - 時間的パラメータを使用して神経刺激のターゲットを制御するためのシステム - Google Patents

時間的パラメータを使用して神経刺激のターゲットを制御するためのシステム Download PDF

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JP5776111B2
JP5776111B2 JP2013513217A JP2013513217A JP5776111B2 JP 5776111 B2 JP5776111 B2 JP 5776111B2 JP 2013513217 A JP2013513217 A JP 2013513217A JP 2013513217 A JP2013513217 A JP 2013513217A JP 5776111 B2 JP5776111 B2 JP 5776111B2
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Japan
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parameter
stimulation
electrical stimulation
signal
emg
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Expired - Fee Related
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JP2013513217A
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Japanese (ja)
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JP2013527007A5 (enExample
JP2013527007A (ja
Inventor
ポール ビー ヨー
ポール ビー ヨー
ウォーレン エム グリル
ウォーレン エム グリル
オルドニェス ファン ガブリエル ヒンカピー
オルドニェス ファン ガブリエル ヒンカピー
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Cardiac Pacemakers Inc
Duke University
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Cardiac Pacemakers Inc
Duke University
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36053—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for vagal stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4029—Detecting, measuring or recording for evaluating the nervous system for evaluating the peripheral nervous systems
    • A61B5/4035—Evaluating the autonomic nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36114—Cardiac control, e.g. by vagal stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36135—Control systems using physiological parameters
    • A61N1/36139—Control systems using physiological parameters with automatic adjustment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36167—Timing, e.g. stimulation onset
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/389—Electromyography [EMG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4029—Detecting, measuring or recording for evaluating the nervous system for evaluating the peripheral nervous systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A61N1/0556—Cuff electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36114—Cardiac control, e.g. by vagal stimulation
    • A61N1/36117—Cardiac control, e.g. by vagal stimulation for treating hypertension

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Cardiology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Electrotherapy Devices (AREA)
JP2013513217A 2010-06-03 2011-05-24 時間的パラメータを使用して神経刺激のターゲットを制御するためのシステム Expired - Fee Related JP5776111B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35118610P 2010-06-03 2010-06-03
US61/351,186 2010-06-03
PCT/US2011/037738 WO2011153027A1 (en) 2010-06-03 2011-05-24 System for controlling target of neurostimulation using temporal parameters

Publications (3)

Publication Number Publication Date
JP2013527007A JP2013527007A (ja) 2013-06-27
JP2013527007A5 JP2013527007A5 (enExample) 2015-03-26
JP5776111B2 true JP5776111B2 (ja) 2015-09-09

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JP2013513217A Expired - Fee Related JP5776111B2 (ja) 2010-06-03 2011-05-24 時間的パラメータを使用して神経刺激のターゲットを制御するためのシステム

Country Status (5)

Country Link
US (2) US9042981B2 (enExample)
EP (1) EP2575959B1 (enExample)
JP (1) JP5776111B2 (enExample)
AU (1) AU2011261702B2 (enExample)
WO (1) WO2011153027A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008092246A1 (en) 2007-01-29 2008-08-07 Simon Fraser University Transvascular nerve stimulation apparatus and methods
EP2575959B1 (en) 2010-06-03 2017-07-12 Cardiac Pacemakers, Inc. System for controlling target of neurostimulation using temporal parameters
US9399134B2 (en) * 2011-03-10 2016-07-26 ElectroCore, LLC Non-invasive vagal nerve stimulation to treat disorders
EP3228351B1 (en) 2012-03-05 2019-06-05 Lungpacer Medical Inc. Transvascular nerve stimulation apparatus
WO2013188965A1 (en) 2012-06-21 2013-12-27 Simon Fraser University Transvascular diaphragm pacing systems and methods of use
CN105873630B (zh) 2013-11-22 2020-01-03 隆佩瑟尔医疗公司 用于通过经血管神经刺激辅助呼吸的装置和方法
JP6537517B2 (ja) 2014-01-21 2019-07-03 ラングペーサー メディカル インコーポレイテッドＬｕｎｇｐａｃｅｒ Ｍｅｄｉｃａｌ Ｉｎｃ． 多電極神経ペーシングの最適化のためのシステムおよび関連する方法
US9782584B2 (en) 2014-06-13 2017-10-10 Nervana, LLC Transcutaneous electrostimulator and methods for electric stimulation
US10130809B2 (en) 2014-06-13 2018-11-20 Nervana, LLC Transcutaneous electrostimulator and methods for electric stimulation
DE102014014942A1 (de) 2014-10-07 2016-04-07 Neuroloop GmbH Implantierbare Anordnung
JP6472724B2 (ja) * 2015-07-09 2019-02-20 オリンパス株式会社 神経刺激装置
US10293164B2 (en) 2017-05-26 2019-05-21 Lungpacer Medical Inc. Apparatus and methods for assisted breathing by transvascular nerve stimulation
CN111163834A (zh) 2017-06-30 2020-05-15 隆佩瑟尔医疗公司 用于预防、减轻和/或治疗认知损伤的装置
US10195429B1 (en) 2017-08-02 2019-02-05 Lungpacer Medical Inc. Systems and methods for intravascular catheter positioning and/or nerve stimulation
US10940308B2 (en) 2017-08-04 2021-03-09 Lungpacer Medical Inc. Systems and methods for trans-esophageal sympathetic ganglion recruitment
US20190175908A1 (en) 2017-12-11 2019-06-13 Lungpacer Medical Inc. Systems and methods for strengthening a respiratory muscle
EP3877043B1 (en) 2018-11-08 2025-04-23 Lungpacer Medical Inc. Stimulation systems and related user interfaces
US11357979B2 (en) 2019-05-16 2022-06-14 Lungpacer Medical Inc. Systems and methods for sensing and stimulation
US11771900B2 (en) 2019-06-12 2023-10-03 Lungpacer Medical Inc. Circuitry for medical stimulation systems
US11938324B2 (en) 2020-05-21 2024-03-26 The Feinstein Institutes For Medical Research Systems and methods for vagus nerve stimulation

Family Cites Families (20)

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AU3304997A (en) 1996-05-31 1998-01-05 Southern Illinois University Methods of modulating aspects of brain neural plasticity by vagus nerve stimulation
EP1079893B1 (en) * 1998-05-08 2005-08-03 Cardiac Pacemakers, Inc. Cardiac pacing using adjustable atrio-ventricular delays
US6341236B1 (en) 1999-04-30 2002-01-22 Ivan Osorio Vagal nerve stimulation techniques for treatment of epileptic seizures
US6466822B1 (en) 2000-04-05 2002-10-15 Neuropace, Inc. Multimodal neurostimulator and process of using it
US6684105B2 (en) * 2001-08-31 2004-01-27 Biocontrol Medical, Ltd. Treatment of disorders by unidirectional nerve stimulation
US7292890B2 (en) * 2002-06-20 2007-11-06 Advanced Bionics Corporation Vagus nerve stimulation via unidirectional propagation of action potentials
US7444184B2 (en) * 2003-05-11 2008-10-28 Neuro And Cardial Technologies, Llc Method and system for providing therapy for bulimia/eating disorders by providing electrical pulses to vagus nerve(s)
US20050137645A1 (en) 2003-12-05 2005-06-23 Juha Voipio Novel method for the adjustment of human and animal vagus nerve stimulation
US8126559B2 (en) * 2004-11-30 2012-02-28 Cardiac Pacemakers, Inc. Neural stimulation with avoidance of inappropriate stimulation
US7551958B2 (en) * 2005-05-24 2009-06-23 Cardiac Pacemakers, Inc. Safety control system for implantable neural stimulator
US8103341B2 (en) * 2006-08-25 2012-01-24 Cardiac Pacemakers, Inc. System for abating neural stimulation side effects
US8457734B2 (en) * 2006-08-29 2013-06-04 Cardiac Pacemakers, Inc. System and method for neural stimulation
US8121692B2 (en) 2006-08-30 2012-02-21 Cardiac Pacemakers, Inc. Method and apparatus for neural stimulation with respiratory feedback
US8050765B2 (en) 2006-08-30 2011-11-01 Cardiac Pacemakers, Inc. Method and apparatus for controlling neural stimulation during disordered breathing
US7801603B2 (en) 2006-09-01 2010-09-21 Cardiac Pacemakers, Inc. Method and apparatus for optimizing vagal nerve stimulation using laryngeal activity
WO2008091928A2 (en) * 2007-01-23 2008-07-31 Kartush Jack M Nerve monitoring device
US8406877B2 (en) * 2007-03-19 2013-03-26 Cardiac Pacemakers, Inc. Selective nerve stimulation with optionally closed-loop capabilities
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US8527045B2 (en) * 2008-10-31 2013-09-03 Medtronic, Inc. Therapy system including cardiac rhythm therapy and neurostimulation capabilities
EP2575959B1 (en) 2010-06-03 2017-07-12 Cardiac Pacemakers, Inc. System for controlling target of neurostimulation using temporal parameters

Also Published As

Publication number Publication date
AU2011261702A1 (en) 2013-01-10
EP2575959A1 (en) 2013-04-10
US20150251007A1 (en) 2015-09-10
US9042981B2 (en) 2015-05-26
EP2575959B1 (en) 2017-07-12
US9630010B2 (en) 2017-04-25
US20110301659A1 (en) 2011-12-08
AU2011261702B2 (en) 2014-11-27
WO2011153027A1 (en) 2011-12-08
JP2013527007A (ja) 2013-06-27

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