AU2011261702B2 - System for controlling target of neurostimulation using temporal parameters - Google Patents
System for controlling target of neurostimulation using temporal parameters Download PDFInfo
- Publication number
- AU2011261702B2 AU2011261702B2 AU2011261702A AU2011261702A AU2011261702B2 AU 2011261702 B2 AU2011261702 B2 AU 2011261702B2 AU 2011261702 A AU2011261702 A AU 2011261702A AU 2011261702 A AU2011261702 A AU 2011261702A AU 2011261702 B2 AU2011261702 B2 AU 2011261702B2
- Authority
- AU
- Australia
- Prior art keywords
- parameter
- stimulation
- parameters
- cardiovascular function
- emg
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 230000002123 temporal effect Effects 0.000 title abstract description 50
- 230000000638 stimulation Effects 0.000 claims abstract description 143
- 210000001186 vagus nerve Anatomy 0.000 claims abstract description 61
- 230000009084 cardiovascular function Effects 0.000 claims abstract description 42
- 210000004717 laryngeal muscle Anatomy 0.000 claims abstract description 39
- 230000036772 blood pressure Effects 0.000 claims description 31
- 230000008602 contraction Effects 0.000 claims description 26
- 230000004872 arterial blood pressure Effects 0.000 claims description 14
- 210000005036 nerve Anatomy 0.000 claims description 12
- 230000008859 change Effects 0.000 claims description 11
- 230000000747 cardiac effect Effects 0.000 claims description 7
- 230000004936 stimulating effect Effects 0.000 claims description 6
- 230000002861 ventricular Effects 0.000 claims description 4
- 238000007918 intramuscular administration Methods 0.000 claims description 3
- 230000035790 physiological processes and functions Effects 0.000 abstract description 42
- 230000007383 nerve stimulation Effects 0.000 abstract description 6
- 230000004118 muscle contraction Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 21
- 238000000034 method Methods 0.000 description 15
- 230000001133 acceleration Effects 0.000 description 9
- 230000006870 function Effects 0.000 description 9
- 230000000763 evoking effect Effects 0.000 description 8
- 238000012544 monitoring process Methods 0.000 description 8
- 230000004913 activation Effects 0.000 description 6
- 239000000835 fiber Substances 0.000 description 5
- 210000004126 nerve fiber Anatomy 0.000 description 5
- 210000000056 organ Anatomy 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- 238000002560 therapeutic procedure Methods 0.000 description 5
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- 230000001225 therapeutic effect Effects 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
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- 238000010586 diagram Methods 0.000 description 2
- 208000035475 disorder Diseases 0.000 description 2
- 230000002526 effect on cardiovascular system Effects 0.000 description 2
- 206010015037 epilepsy Diseases 0.000 description 2
- 210000003666 myelinated nerve fiber Anatomy 0.000 description 2
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- 238000007634 remodeling Methods 0.000 description 2
- 208000024827 Alzheimer disease Diseases 0.000 description 1
- 208000000103 Anorexia Nervosa Diseases 0.000 description 1
- 208000019901 Anxiety disease Diseases 0.000 description 1
- 0 CCC1(CCCC1)*#C Chemical compound CCC1(CCCC1)*#C 0.000 description 1
- 241000282465 Canis Species 0.000 description 1
- 208000020446 Cardiac disease Diseases 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 208000030814 Eating disease Diseases 0.000 description 1
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- 208000010473 Hoarseness Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 208000012902 Nervous system disease Diseases 0.000 description 1
- 208000025966 Neurological disease Diseases 0.000 description 1
- 208000008589 Obesity Diseases 0.000 description 1
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- 230000003556 anti-epileptic effect Effects 0.000 description 1
- 239000001961 anticonvulsive agent Substances 0.000 description 1
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- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 208000019622 heart disease Diseases 0.000 description 1
- 230000004217 heart function Effects 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36053—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for vagal stimulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/40—Detecting, measuring or recording for evaluating the nervous system
- A61B5/4029—Detecting, measuring or recording for evaluating the nervous system for evaluating the peripheral nervous systems
- A61B5/4035—Evaluating the autonomic nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36114—Cardiac control, e.g. by vagal stimulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36135—Control systems using physiological parameters
- A61N1/36139—Control systems using physiological parameters with automatic adjustment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36146—Control systems specified by the stimulation parameters
- A61N1/36167—Timing, e.g. stimulation onset
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/389—Electromyography [EMG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/40—Detecting, measuring or recording for evaluating the nervous system
- A61B5/4029—Detecting, measuring or recording for evaluating the nervous system for evaluating the peripheral nervous systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0551—Spinal or peripheral nerve electrodes
- A61N1/0556—Cuff electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36114—Cardiac control, e.g. by vagal stimulation
- A61N1/36117—Cardiac control, e.g. by vagal stimulation for treating hypertension
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Physiology (AREA)
- Cardiology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Electrotherapy Devices (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35118610P | 2010-06-03 | 2010-06-03 | |
| US61/351,186 | 2010-06-03 | ||
| PCT/US2011/037738 WO2011153027A1 (en) | 2010-06-03 | 2011-05-24 | System for controlling target of neurostimulation using temporal parameters |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2011261702A1 AU2011261702A1 (en) | 2013-01-10 |
| AU2011261702B2 true AU2011261702B2 (en) | 2014-11-27 |
Family
ID=44504457
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2011261702A Ceased AU2011261702B2 (en) | 2010-06-03 | 2011-05-24 | System for controlling target of neurostimulation using temporal parameters |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US9042981B2 (enExample) |
| EP (1) | EP2575959B1 (enExample) |
| JP (1) | JP5776111B2 (enExample) |
| AU (1) | AU2011261702B2 (enExample) |
| WO (1) | WO2011153027A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008092246A1 (en) | 2007-01-29 | 2008-08-07 | Simon Fraser University | Transvascular nerve stimulation apparatus and methods |
| EP2575959B1 (en) | 2010-06-03 | 2017-07-12 | Cardiac Pacemakers, Inc. | System for controlling target of neurostimulation using temporal parameters |
| US9399134B2 (en) * | 2011-03-10 | 2016-07-26 | ElectroCore, LLC | Non-invasive vagal nerve stimulation to treat disorders |
| EP3228351B1 (en) | 2012-03-05 | 2019-06-05 | Lungpacer Medical Inc. | Transvascular nerve stimulation apparatus |
| WO2013188965A1 (en) | 2012-06-21 | 2013-12-27 | Simon Fraser University | Transvascular diaphragm pacing systems and methods of use |
| CN105873630B (zh) | 2013-11-22 | 2020-01-03 | 隆佩瑟尔医疗公司 | 用于通过经血管神经刺激辅助呼吸的装置和方法 |
| JP6537517B2 (ja) | 2014-01-21 | 2019-07-03 | ラングペーサー メディカル インコーポレイテッドＬｕｎｇｐａｃｅｒ Ｍｅｄｉｃａｌ Ｉｎｃ． | 多電極神経ペーシングの最適化のためのシステムおよび関連する方法 |
| US9782584B2 (en) | 2014-06-13 | 2017-10-10 | Nervana, LLC | Transcutaneous electrostimulator and methods for electric stimulation |
| US10130809B2 (en) | 2014-06-13 | 2018-11-20 | Nervana, LLC | Transcutaneous electrostimulator and methods for electric stimulation |
| DE102014014942A1 (de) | 2014-10-07 | 2016-04-07 | Neuroloop GmbH | Implantierbare Anordnung |
| JP6472724B2 (ja) * | 2015-07-09 | 2019-02-20 | オリンパス株式会社 | 神経刺激装置 |
| US10293164B2 (en) | 2017-05-26 | 2019-05-21 | Lungpacer Medical Inc. | Apparatus and methods for assisted breathing by transvascular nerve stimulation |
| CN111163834A (zh) | 2017-06-30 | 2020-05-15 | 隆佩瑟尔医疗公司 | 用于预防、减轻和/或治疗认知损伤的装置 |
| US10195429B1 (en) | 2017-08-02 | 2019-02-05 | Lungpacer Medical Inc. | Systems and methods for intravascular catheter positioning and/or nerve stimulation |
| US10940308B2 (en) | 2017-08-04 | 2021-03-09 | Lungpacer Medical Inc. | Systems and methods for trans-esophageal sympathetic ganglion recruitment |
| US20190175908A1 (en) | 2017-12-11 | 2019-06-13 | Lungpacer Medical Inc. | Systems and methods for strengthening a respiratory muscle |
| EP3877043B1 (en) | 2018-11-08 | 2025-04-23 | Lungpacer Medical Inc. | Stimulation systems and related user interfaces |
| US11357979B2 (en) | 2019-05-16 | 2022-06-14 | Lungpacer Medical Inc. | Systems and methods for sensing and stimulation |
| US11771900B2 (en) | 2019-06-12 | 2023-10-03 | Lungpacer Medical Inc. | Circuitry for medical stimulation systems |
| US11938324B2 (en) | 2020-05-21 | 2024-03-26 | The Feinstein Institutes For Medical Research | Systems and methods for vagus nerve stimulation |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060271108A1 (en) * | 2005-05-24 | 2006-11-30 | Cardiac Pacemakers, Inc. | Safety control system for implantable neural stimulator |
| US20080051839A1 (en) * | 2006-08-25 | 2008-02-28 | Imad Libbus | System for abating neural stimulation side effects |
| US20080234780A1 (en) * | 2007-03-19 | 2008-09-25 | Cardiac Pacemakers | Selective nerve stimulation with optionally closed-loop capabilities |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3304997A (en) | 1996-05-31 | 1998-01-05 | Southern Illinois University | Methods of modulating aspects of brain neural plasticity by vagus nerve stimulation |
| EP1079893B1 (en) * | 1998-05-08 | 2005-08-03 | Cardiac Pacemakers, Inc. | Cardiac pacing using adjustable atrio-ventricular delays |
| US6341236B1 (en) | 1999-04-30 | 2002-01-22 | Ivan Osorio | Vagal nerve stimulation techniques for treatment of epileptic seizures |
| US6466822B1 (en) | 2000-04-05 | 2002-10-15 | Neuropace, Inc. | Multimodal neurostimulator and process of using it |
| US6684105B2 (en) * | 2001-08-31 | 2004-01-27 | Biocontrol Medical, Ltd. | Treatment of disorders by unidirectional nerve stimulation |
| US7292890B2 (en) * | 2002-06-20 | 2007-11-06 | Advanced Bionics Corporation | Vagus nerve stimulation via unidirectional propagation of action potentials |
| US7444184B2 (en) * | 2003-05-11 | 2008-10-28 | Neuro And Cardial Technologies, Llc | Method and system for providing therapy for bulimia/eating disorders by providing electrical pulses to vagus nerve(s) |
| US20050137645A1 (en) | 2003-12-05 | 2005-06-23 | Juha Voipio | Novel method for the adjustment of human and animal vagus nerve stimulation |
| US8126559B2 (en) * | 2004-11-30 | 2012-02-28 | Cardiac Pacemakers, Inc. | Neural stimulation with avoidance of inappropriate stimulation |
| US8457734B2 (en) * | 2006-08-29 | 2013-06-04 | Cardiac Pacemakers, Inc. | System and method for neural stimulation |
| US8121692B2 (en) | 2006-08-30 | 2012-02-21 | Cardiac Pacemakers, Inc. | Method and apparatus for neural stimulation with respiratory feedback |
| US8050765B2 (en) | 2006-08-30 | 2011-11-01 | Cardiac Pacemakers, Inc. | Method and apparatus for controlling neural stimulation during disordered breathing |
| US7801603B2 (en) | 2006-09-01 | 2010-09-21 | Cardiac Pacemakers, Inc. | Method and apparatus for optimizing vagal nerve stimulation using laryngeal activity |
| WO2008091928A2 (en) * | 2007-01-23 | 2008-07-31 | Kartush Jack M | Nerve monitoring device |
| WO2010005482A1 (en) | 2008-07-08 | 2010-01-14 | Cardiac Pacemakers, Inc. | Systems for delivering vagal nerve stimulation |
| US8527045B2 (en) * | 2008-10-31 | 2013-09-03 | Medtronic, Inc. | Therapy system including cardiac rhythm therapy and neurostimulation capabilities |
| EP2575959B1 (en) | 2010-06-03 | 2017-07-12 | Cardiac Pacemakers, Inc. | System for controlling target of neurostimulation using temporal parameters |
-
2011
- 2011-05-24 EP EP11723161.3A patent/EP2575959B1/en not_active Not-in-force
- 2011-05-24 AU AU2011261702A patent/AU2011261702B2/en not_active Ceased
- 2011-05-24 US US13/114,686 patent/US9042981B2/en active Active
- 2011-05-24 WO PCT/US2011/037738 patent/WO2011153027A1/en not_active Ceased
- 2011-05-24 JP JP2013513217A patent/JP5776111B2/ja not_active Expired - Fee Related
-
2015
- 2015-05-22 US US14/720,513 patent/US9630010B2/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060271108A1 (en) * | 2005-05-24 | 2006-11-30 | Cardiac Pacemakers, Inc. | Safety control system for implantable neural stimulator |
| US20080051839A1 (en) * | 2006-08-25 | 2008-02-28 | Imad Libbus | System for abating neural stimulation side effects |
| US20080234780A1 (en) * | 2007-03-19 | 2008-09-25 | Cardiac Pacemakers | Selective nerve stimulation with optionally closed-loop capabilities |
Also Published As
| Publication number | Publication date |
|---|---|
| JP5776111B2 (ja) | 2015-09-09 |
| AU2011261702A1 (en) | 2013-01-10 |
| EP2575959A1 (en) | 2013-04-10 |
| US20150251007A1 (en) | 2015-09-10 |
| US9042981B2 (en) | 2015-05-26 |
| EP2575959B1 (en) | 2017-07-12 |
| US9630010B2 (en) | 2017-04-25 |
| US20110301659A1 (en) | 2011-12-08 |
| WO2011153027A1 (en) | 2011-12-08 |
| JP2013527007A (ja) | 2013-06-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |