JP5769374B2 - 標的を定めた変異誘発によって改変された変異δ８デサチュラーゼ遺伝子及び多価不飽和脂肪酸の製造におけるそれらの使用 - Google Patents

標的を定めた変異誘発によって改変された変異δ８デサチュラーゼ遺伝子及び多価不飽和脂肪酸の製造におけるそれらの使用 Download PDF

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JP5769374B2
JP5769374B2 JP2009540294A JP2009540294A JP5769374B2 JP 5769374 B2 JP5769374 B2 JP 5769374B2 JP 2009540294 A JP2009540294 A JP 2009540294A JP 2009540294 A JP2009540294 A JP 2009540294A JP 5769374 B2 JP5769374 B2 JP 5769374B2
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desaturase
egd8s
seq
sequence
pfmd8s
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JP2010512146A (ja
JP2010512146A5 (enExample
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ハワード グレン ダムード
ハワード グレン ダムード
ホンシアン ヒー
ホンシアン ヒー
デル−イン リアオ
デル−イン リアオ
クイン クン ズー
クイン クン ズー
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EIDP Inc
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EI Du Pont de Nemours and Co
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083—Miscellaneous (1.14.99)

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  • Zoology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
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  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
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  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2009540294A 2006-12-07 2007-12-05 標的を定めた変異誘発によって改変された変異δ８デサチュラーゼ遺伝子及び多価不飽和脂肪酸の製造におけるそれらの使用 Expired - Fee Related JP5769374B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/635,258 US7709239B2 (en) 2006-12-07 2006-12-07 Mutant Δ8 desaturase genes engineered by targeted mutagenesis and their use in making polyunsaturated fatty acids
US11/635,258 2006-12-07
PCT/US2007/025001 WO2008073271A1 (en) 2006-12-07 2007-12-05 Mutant delta8 desaturase genes engineered by targeted mutagenesis and their use in making polyunsaturated fatty acids

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JP2010512146A JP2010512146A (ja) 2010-04-22
JP2010512146A5 JP2010512146A5 (enExample) 2011-01-27
JP5769374B2 true JP5769374B2 (ja) 2015-08-26

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US (2) US7709239B2 (enExample)
EP (1) EP2087106B1 (enExample)
JP (1) JP5769374B2 (enExample)
CN (1) CN101627118B (enExample)
AU (1) AU2007332918B2 (enExample)
CA (1) CA2669217C (enExample)
DK (1) DK2087106T3 (enExample)
WO (1) WO2008073271A1 (enExample)

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JP5711968B2 (ja) * 2007-10-03 2015-05-07 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーＥ．Ｉ．Ｄｕ Ｐｏｎｔ Ｄｅ Ｎｅｍｏｕｒｓ Ａｎｄ Ｃｏｍｐａｎｙ 高エイコサペンタエン酸を生成するためのヤロウィア・リポリティカ（ＹａｒｒｏｗｉａＬｉｐｏｌｙｔｉｃａ）の最適化株
EP2358869B1 (en) * 2008-10-06 2014-03-26 Abbott Laboratories Delta-8 desaturase genes, enzymes encoded thereby and uses thereof
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DK2442666T3 (da) 2009-06-16 2015-07-13 Du Pont Olier med højt indhold af eicosapentaensyre fra forbedrede og optimerede stammer af yarrowia lipolytica
CA2761589C (en) 2009-06-16 2017-12-19 E. I. Du Pont De Nemours And Company Improved optimized strains of yarrowia lipolytica for high eicosapentaenoic acid production
AU2010260227B2 (en) 2009-06-16 2015-01-29 E. I. Du Pont De Nemours And Company Improvement of long chain omega-3 and omega-6 polyunsaturated fatty acid biosynthesis by expression of acyl-CoA lysophospholipid acyltransferases
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US20120040076A1 (en) 2010-08-11 2012-02-16 E. I. Du Pont De Nemours And Company Aquaculture feed compositions
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CN103249834B (zh) 2010-08-26 2016-10-26 纳幕尔杜邦公司 生产高水平二十碳五烯酸的重组微生物宿主细胞
EP2609202A1 (en) 2010-08-26 2013-07-03 E.I. Du Pont De Nemours And Company Mutant hpgg motif and hdash motif delta-5 desaturases and their use in making polyunsaturated fatty acids
US8980589B2 (en) 2010-08-26 2015-03-17 E I Du Pont De Nemours And Company Mutant delta-9 elongases and their use in making polyunsaturated fatty acids
MX2013004944A (es) * 2010-11-05 2013-06-28 Basf Plant Science Co Gmbh Metodo para aumentar el rendimiento y la produccion de quimicos finos en las plantas.
JP2014503216A (ja) 2010-12-30 2014-02-13 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー スクロース利用のための、ヤロウィア・リポリティカ（Ｙａｒｒｏｗｉａｌｉｐｏｌｙｔｉｃａ）におけるサッカロミセス・セレビシア（Ｓａｃｃｈａｒｏｍｙｃｅｓｃｅｒｅｖｉｓｉａｅ）ＳＵＣ２遺伝子の使用
US20130040340A1 (en) 2011-02-07 2013-02-14 E. I. Du Pont De Nemours And Company Production of alcohol esters in situ using alcohols and fatty acids produced by microorganisms
EP2691518A1 (en) 2011-03-31 2014-02-05 E.I. Du Pont De Nemours And Company Yarrowia diacylglycerol acyltransferase promoter regions for gene expression in yeast
US8906650B2 (en) 2011-04-01 2014-12-09 E I Du Pont De Nemours And Company Yarrowia esterase/lipase promoter regions for gene expression in yeast
US20120247066A1 (en) 2011-04-01 2012-10-04 Ice House America, Llc Ice bagging apparatus and methods
WO2012138613A1 (en) 2011-04-05 2012-10-11 E. I. Du Pont De Nemours And Company Yarrowia n-alkane-hydroxylating cytochrome p450 promoter regions for gene expression in yeast
WO2012138612A1 (en) 2011-04-07 2012-10-11 E. I. Du Pont De Nemours And Company Yarrowia peroxisomal 2,4-dienoyl-coa reductase promoter regions for gene expression in yeast
BR122019026149A8 (pt) 2012-06-15 2022-06-28 Commw Scient Ind Res Org Célula hospedeira, processo de produzir um lipídio de planta extraído, método de produzir semente, farinha de semente, método para produzir um produto alimentício, uso e processo para produzir ésteres de etila
US9005940B2 (en) 2012-12-21 2015-04-14 E I Du Pont De Nemours And Company Down-regulation of a polynucleotide encoding a Sou2 sorbitol utilization protein to modify lipid production in microbial cells
PE20170253A1 (es) 2013-12-18 2017-04-14 Nuseed Pty Ltd Lipido que comprende acidos grasos poliinsaturados de cadena larga
AU2015281791A1 (en) 2014-06-27 2017-01-12 Commonwealth Scientific And Industrial Research Organisation Lipid comprising docosapentaenoic acid
CN104293769B (zh) * 2014-10-27 2016-06-01 徐毅 一种来源于绿色巴夫藻的delta8去饱和酶新基因
AU2020281709B2 (en) * 2019-05-28 2024-08-08 Centre National De La Recherche Scientifique Variants of terminal deoxynucleotidyl transferase and uses thereof.

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US20080138868A1 (en) 2008-06-12
CN101627118B (zh) 2013-07-17
JP2010512146A (ja) 2010-04-22
CA2669217A1 (en) 2008-06-19
US7709239B2 (en) 2010-05-04
WO2008073271A1 (en) 2008-06-19
WO2008073271A9 (en) 2009-04-30
AU2007332918B2 (en) 2013-02-07
EP2087106B1 (en) 2015-03-04
US20100297713A1 (en) 2010-11-25
DK2087106T3 (en) 2015-06-08
CA2669217C (en) 2015-07-14
CN101627118A (zh) 2010-01-13
EP2087106A1 (en) 2009-08-12
US8026089B2 (en) 2011-09-27
AU2007332918A1 (en) 2008-06-19

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