JP5769374B2 - 標的を定めた変異誘発によって改変された変異δ８デサチュラーゼ遺伝子及び多価不飽和脂肪酸の製造におけるそれらの使用 - Google Patents

標的を定めた変異誘発によって改変された変異δ８デサチュラーゼ遺伝子及び多価不飽和脂肪酸の製造におけるそれらの使用 Download PDF

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JP5769374B2
JP5769374B2 JP2009540294A JP2009540294A JP5769374B2 JP 5769374 B2 JP5769374 B2 JP 5769374B2 JP 2009540294 A JP2009540294 A JP 2009540294A JP 2009540294 A JP2009540294 A JP 2009540294A JP 5769374 B2 JP5769374 B2 JP 5769374B2
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desaturase
egd8s
seq
sequence
pfmd8s
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JP2010512146A (ja
JP2010512146A5 (enExample
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ハワード グレン ダムード
ハワード グレン ダムード
ホンシアン ヒー
ホンシアン ヒー
デル−イン リアオ
デル−イン リアオ
クイン クン ズー
クイン クン ズー
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EIDP Inc
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EI Du Pont de Nemours and Co
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083—Miscellaneous (1.14.99)

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  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
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  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2009540294A 2006-12-07 2007-12-05 標的を定めた変異誘発によって改変された変異δ８デサチュラーゼ遺伝子及び多価不飽和脂肪酸の製造におけるそれらの使用 Expired - Fee Related JP5769374B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/635,258 US7709239B2 (en) 2006-12-07 2006-12-07 Mutant Δ8 desaturase genes engineered by targeted mutagenesis and their use in making polyunsaturated fatty acids
US11/635,258 2006-12-07
PCT/US2007/025001 WO2008073271A1 (en) 2006-12-07 2007-12-05 Mutant delta8 desaturase genes engineered by targeted mutagenesis and their use in making polyunsaturated fatty acids

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JP2010512146A JP2010512146A (ja) 2010-04-22
JP2010512146A5 JP2010512146A5 (enExample) 2011-01-27
JP5769374B2 true JP5769374B2 (ja) 2015-08-26

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US (2) US7709239B2 (enExample)
EP (1) EP2087106B1 (enExample)
JP (1) JP5769374B2 (enExample)
CN (1) CN101627118B (enExample)
AU (1) AU2007332918B2 (enExample)
CA (1) CA2669217C (enExample)
DK (1) DK2087106T3 (enExample)
WO (1) WO2008073271A1 (enExample)

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CA2744716C (en) 2008-12-18 2017-05-23 E.I. Du Pont De Nemours And Company Reducing byproduction of malonates in a fermentation process
BRPI1009690A2 (pt) 2009-06-16 2015-08-25 Du Pont "célula hospedeira microbiana oleaginosa, óleo, método de elaboração de um óleo, método de aumento da eficiência de conversão de alongamento de c18 para c20 em uma célula hospedeira recombinante microbiana oleaginosa e método de aumento da eficiência de conversão de dessaturação (delta) 4 em uma célula hospedeira recombinante microbiana oleaginosa produtora de ácidos graxos póli-insaturados de cadeia longa"
WO2010147907A1 (en) 2009-06-16 2010-12-23 E. I. Du Pont De Nemours And Company High eicosapentaenoic acid oils from improved optimized strains of yarrowia lipolytica
CN102803289B (zh) 2009-06-16 2015-07-22 纳幕尔杜邦公司 用于高水平生产二十碳五烯酸的改善的优化的解脂耶氏酵母菌株
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CN103282474A (zh) 2010-04-22 2013-09-04 纳幕尔杜邦公司 从微生物生物质中获得包含多不饱和脂肪酸的组合物的方法
WO2012021686A1 (en) 2010-08-11 2012-02-16 E. I. Du Pont De Nemours And Company Improved aquaculture meat products
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US20120040076A1 (en) 2010-08-11 2012-02-16 E. I. Du Pont De Nemours And Company Aquaculture feed compositions
WO2012027676A1 (en) 2010-08-26 2012-03-01 E. I. Du Pont De Nemours And Company Mutant delta-9 elongases and their use in making polyunsaturated fatty acids
AU2011293189B2 (en) 2010-08-26 2017-02-16 E. I. Du Pont De Nemours And Company Mutant HPGG motif and HDASH motif delta-5 desaturases and their use in making polyunsaturated fatty acids
US8703473B2 (en) 2010-08-26 2014-04-22 E I Du Pont De Nemours And Company Recombinant microbial host cells for high eicosapentaenoic acid production
PH12013500995A1 (en) * 2010-11-05 2017-08-23 Basf Plant Science Co Gmbh Methods for increasing yield and fine chemical production in plants
BR112013016769A2 (pt) 2010-12-30 2016-10-11 Du Pont yarrowia lipolytica transformada e método para produzir pelo menos um produto não nativo de interesse
US20130040340A1 (en) 2011-02-07 2013-02-14 E. I. Du Pont De Nemours And Company Production of alcohol esters in situ using alcohols and fatty acids produced by microorganisms
US8969049B2 (en) 2011-03-31 2015-03-03 E I Du Pont De Nemours And Company Yarrowia diacylglycerol acyltransferase promoter regions for gene expression in yeast
US20120247066A1 (en) 2011-04-01 2012-10-04 Ice House America, Llc Ice bagging apparatus and methods
EP2694665A1 (en) 2011-04-01 2014-02-12 E. I. Du Pont de Nemours and Company Yarrowia esterase/lipase promoter regions for gene expression in yeast
WO2012138613A1 (en) 2011-04-05 2012-10-11 E. I. Du Pont De Nemours And Company Yarrowia n-alkane-hydroxylating cytochrome p450 promoter regions for gene expression in yeast
EP2702148A1 (en) 2011-04-07 2014-03-05 E.I. Du Pont De Nemours And Company Yarrowia peroxisomal 2,4-dienoyl-coa reductase promoter regions for gene expression in yeast
HUE033766T2 (en) 2012-06-15 2018-01-29 Commw Scient Ind Res Org Production of long chain polyunsaturated fatty acids in plant cells
CA2892516A1 (en) 2012-12-21 2014-06-26 E. I. Du Pont De Nemours And Company Down-regulation of a polynucleotide encoding a sou2 sorbitol utilization protein to modify lipid production in microbial cells
EA037817B1 (ru) 2013-12-18 2021-05-25 Коммонвелт Сайнтифик Энд Индастриэл Рисерч Организэйшн Экстрагированный растительный липид, содержащий длинноцепочечные полиненасыщенные жирные кислоты
CA2953008C (en) 2014-06-27 2024-03-19 Nuseed Pty Ltd Lipid comprising docosapentaenoic acid
CN104293769B (zh) * 2014-10-27 2016-06-01 徐毅 一种来源于绿色巴夫藻的delta8去饱和酶新基因
ES2982551T3 (es) * 2019-05-28 2024-10-16 Dna Script Variantes de desoxinucleotidil transferasa terminal y usos de las mismas

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US7465793B2 (en) * 2006-04-20 2008-12-16 E.I. Du Pont De Nemours And Company Synthetic Δ17 desaturase derived from Phytophthora ramourum and its use in making polyunsaturated fatty acids
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AU2007332918B2 (en) 2013-02-07
CN101627118B (zh) 2013-07-17
WO2008073271A1 (en) 2008-06-19
US7709239B2 (en) 2010-05-04
AU2007332918A1 (en) 2008-06-19
CA2669217C (en) 2015-07-14
JP2010512146A (ja) 2010-04-22
WO2008073271A9 (en) 2009-04-30
US20080138868A1 (en) 2008-06-12
DK2087106T3 (en) 2015-06-08
CN101627118A (zh) 2010-01-13
EP2087106A1 (en) 2009-08-12
US20100297713A1 (en) 2010-11-25
EP2087106B1 (en) 2015-03-04
US8026089B2 (en) 2011-09-27
CA2669217A1 (en) 2008-06-19

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