JP5763525B2 - 粒子からの核酸複合体の送達 - Google Patents

粒子からの核酸複合体の送達 Download PDF

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JP5763525B2
JP5763525B2 JP2011508670A JP2011508670A JP5763525B2 JP 5763525 B2 JP5763525 B2 JP 5763525B2 JP 2011508670 A JP2011508670 A JP 2011508670A JP 2011508670 A JP2011508670 A JP 2011508670A JP 5763525 B2 JP5763525 B2 JP 5763525B2
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nucleic acid
particles
polymer
solution
acid complex
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JP2011520813A5 (enExample
JP2011520813A (ja
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スラヘル，ヨラム
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サーモディクス，インコーポレイティド
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    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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JP2011508670A 2008-05-07 2009-05-07 粒子からの核酸複合体の送達 Expired - Fee Related JP5763525B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5104108P 2008-05-07 2008-05-07
US61/051,041 2008-05-07
PCT/US2009/043158 WO2009137689A2 (en) 2008-05-07 2009-05-07 Delivery of nucleic acid complexes from particles

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JP2011520813A JP2011520813A (ja) 2011-07-21
JP2011520813A5 JP2011520813A5 (enExample) 2012-06-28
JP5763525B2 true JP5763525B2 (ja) 2015-08-12

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US (1) US8936811B2 (enExample)
EP (1) EP2296630A2 (enExample)
JP (1) JP5763525B2 (enExample)
CA (1) CA2723192A1 (enExample)
WO (1) WO2009137689A2 (enExample)

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JP5763525B2 (ja) 2008-05-07 2015-08-12 サーモディクス，インコーポレイティド 粒子からの核酸複合体の送達
NZ594245A (en) * 2008-12-26 2013-02-22 Samyang Biopharmaceuticals Pharmaceutical composition containing an anionic drug, a cationic lipid and an amphiphilic block copolymer
WO2010118238A2 (en) 2009-04-08 2010-10-14 Surmodics, Inc. Controlled release devices and methods for delivery of nucleic acids
WO2010118213A2 (en) * 2009-04-08 2010-10-14 Surmodics, Inc. Particles for delivery of nucleic acids and related devices and methods
EP2386647A1 (de) * 2010-05-10 2011-11-16 Qiagen GmbH Verfahren zur Transfektion einer eurkaryotischen Zelle
US20110319473A1 (en) * 2010-06-29 2011-12-29 Surmodics, Inc. Compositions and methods for enhancement of nucleic acid delivery
US8946170B2 (en) * 2010-07-21 2015-02-03 Allergan, Inc. Sustained release siRNA for ocular drug delivery
EP2636748A4 (en) * 2010-11-05 2014-04-02 Ezaki Glico Co SUGAR-CONTAINING AMINOGLUCAN, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF
US8901092B2 (en) 2010-12-29 2014-12-02 Surmodics, Inc. Functionalized polysaccharides for active agent delivery
US9750445B2 (en) 2013-06-28 2017-09-05 Verily Life Sciences Llc Porous polymeric formulation prepared using porogens
US9551680B2 (en) 2013-06-28 2017-01-24 Verily Life Sciences Llc Chemically reactive enzyme immobilization
US9441258B2 (en) * 2013-06-28 2016-09-13 Verily Life Sciences LLP Enzyme immobilization by crosslinking
US9828620B2 (en) 2013-06-28 2017-11-28 Verily Life Sciences Llc Porous polymeric formulation prepared using monomer
WO2015088990A1 (en) 2013-12-09 2015-06-18 Durect Corporation Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same
US9987228B2 (en) 2014-11-18 2018-06-05 National Institute For Materials Science Method for producing porous particle
ES2901102T3 (es) * 2015-12-18 2022-03-21 Samyang Holdings Corp Método para preparar una micela polimérica que contiene fármaco aniónico
KR101882133B1 (ko) * 2017-02-21 2018-07-25 성균관대학교산학협력단 핵산과 결합 가능한 펩타이드를 이용하여 핵산을 분리하는 방법
US11590080B2 (en) 2017-12-18 2023-02-28 C.R. Bard, Inc. Drug-loaded biodegradable microbead compositions including drug-containing vesicular agents
AU2018390560B2 (en) * 2017-12-18 2024-09-19 C. R. Bard, Inc. Drug-loaded microbead compositions, embolization compositions and associated methods
US20240131184A1 (en) * 2019-10-10 2024-04-25 University Of Maryland, Baltimore Compositions and methods for delivering nucleic acids to cells
US20220313616A1 (en) * 2021-03-30 2022-10-06 Celanese Eva Performance Polymers Llc Implantable Medical Device for the Delivery of Nucleic Acid-Encapsulated Particles
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