JP5762666B2 - フロログルシノールの生合成およびそれからの１，３−ジヒドロキシベンゼンの製造 - Google Patents

フロログルシノールの生合成およびそれからの１，３−ジヒドロキシベンゼンの製造 Download PDF

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JP5762666B2
JP5762666B2 JP2007536764A JP2007536764A JP5762666B2 JP 5762666 B2 JP5762666 B2 JP 5762666B2 JP 2007536764 A JP2007536764 A JP 2007536764A JP 2007536764 A JP2007536764 A JP 2007536764A JP 5762666 B2 JP5762666 B2 JP 5762666B2
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recombinant
phld
phloroglucinol
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coa
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JP2008517588A (ja
JP2008517588A5 (enExample
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ジョン、ダブリュ．フロスト
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Michigan State University MSU
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • C—CHEMISTRY; METALLURGY
    • C06—EXPLOSIVES; MATCHES
    • C06B—EXPLOSIVES OR THERMIC COMPOSITIONS; MANUFACTURE THEREOF; USE OF SINGLE SUBSTANCES AS EXPLOSIVES
    • C06B25/00—Compositions containing a nitrated organic compound
    • C06B25/04—Compositions containing a nitrated organic compound the nitrated compound being an aromatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/06—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by conversion of non-aromatic six-membered rings or of such rings formed in situ into aromatic six-membered rings, e.g. by dehydrogenation
    • C07C37/07—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by conversion of non-aromatic six-membered rings or of such rings formed in situ into aromatic six-membered rings, e.g. by dehydrogenation with simultaneous reduction of C=O group in that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/02—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with no unsaturation outside the aromatic ring
    • C07C39/10—Polyhydroxy benzenes; Alkylated derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
JP2007536764A 2004-10-12 2005-10-11 フロログルシノールの生合成およびそれからの１，３−ジヒドロキシベンゼンの製造 Expired - Fee Related JP5762666B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US61795904P 2004-10-12 2004-10-12
US61802404P 2004-10-12 2004-10-12
US60/618,024 2004-10-12
US60/617,959 2004-10-12
PCT/US2005/036291 WO2006044290A2 (en) 2004-10-12 2005-10-11 Biosynthesis of philoroglucinol and preparation of 1,3-dihydroxybenzene therefrom

Publications (3)

Publication Number Publication Date
JP2008517588A JP2008517588A (ja) 2008-05-29
JP2008517588A5 JP2008517588A5 (enExample) 2008-12-04
JP5762666B2 true JP5762666B2 (ja) 2015-08-12

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JP2007536764A Expired - Fee Related JP5762666B2 (ja) 2004-10-12 2005-10-11 フロログルシノールの生合成およびそれからの１，３−ジヒドロキシベンゼンの製造

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US (2) US7943362B2 (enExample)
EP (1) EP1799828B1 (enExample)
JP (1) JP5762666B2 (enExample)
KR (1) KR101340580B1 (enExample)
BR (1) BRPI0515994A (enExample)
WO (1) WO2006044290A2 (enExample)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101340580B1 (ko) 2004-10-12 2013-12-11 보드 오브 트러스티즈 오브 미시건 스테이트 유니버시티 플로로글루시놀의 생합성 및 이로부터1,3-디하이드록시벤젠의 합성
CN101903513B (zh) * 2007-01-12 2013-08-21 科罗拉多大学董事会法人 增强微生物对产生的有机化学物质的耐受性的组合物和方法
US8048624B1 (en) 2007-12-04 2011-11-01 Opx Biotechnologies, Inc. Compositions and methods for 3-hydroxypropionate bio-production from biomass
WO2010080388A1 (en) * 2008-12-18 2010-07-15 E. I. Du Pont De Nemours And Company Reducing byproduction of malonates in a fermentation process
US8367859B2 (en) 2009-06-16 2013-02-05 Amyris, Inc. Cyclohexane 1,4 carboxylates
KR20120027531A (ko) 2009-06-16 2012-03-21 아미리스 인코퍼레이티드 시클로헥센 1,4-카르복실레이트
US8415496B2 (en) 2009-06-16 2013-04-09 Amyris, Inc. Biobased polyesters
US20110282078A1 (en) 2009-06-16 2011-11-17 Draths Corporation Cyclohexene 1,4 -carboxylates
WO2010148049A2 (en) 2009-06-16 2010-12-23 Draths Corporation Preparation of trans, trans muconic acid and trans, trans muconates
US8809027B1 (en) 2009-09-27 2014-08-19 Opx Biotechnologies, Inc. Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase
KR20140015136A (ko) 2009-09-27 2014-02-06 더 리젠츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코포레이트 3-히드록시프로피온산 및 다른 생성물의 제조 방법
WO2011063363A2 (en) * 2009-11-20 2011-05-26 Opx Biotechnologies, Inc. Production of an organic acid and/or related chemicals
WO2012003461A2 (en) * 2010-07-02 2012-01-05 Draths Corporation Phloroglucinol synthases and methods of making and using the same
WO2012006244A1 (en) * 2010-07-06 2012-01-12 Draths Corporation Method for producing phloroglucinol and dihydrophloroglucinol
WO2012006245A1 (en) * 2010-07-06 2012-01-12 Draths Corporation Phloroglucinol reductase and methods of making and using the same
FR2980801B1 (fr) 2011-09-29 2016-02-05 Centre Nat Rech Scient Utilisation de "polyketide synthases" de type iii (pks iii) recombinantes d'algues brunes marines
WO2013151379A1 (ko) 2012-04-06 2013-10-10 엘지전자 주식회사 경로 계산 방법, 경로 획득 방법 또는 이를 위한 단말
US8853189B2 (en) 2012-05-31 2014-10-07 Prima Innovations, Llc Antispasmodic 1,2-Diols and 1,2,3-triols
CA2881666A1 (en) 2012-08-10 2014-02-13 Opx Biotechnologies, Inc. Microorganisms and methods for the production of fatty acids and fatty acid derived products
US9267158B2 (en) 2013-03-14 2016-02-23 Intrexon Corporation Biological production of multi-carbon compounds from methane
WO2014152434A2 (en) * 2013-03-15 2014-09-25 Genomatica, Inc. Microorganisms and methods for producing butadiene and related compounds by formate assimilation
US20150057465A1 (en) 2013-03-15 2015-02-26 Opx Biotechnologies, Inc. Control of growth-induction-production phases
EP2976141A4 (en) 2013-03-15 2016-10-05 Cargill Inc FLASHING FOR PRODUCTION CLEANING AND RECOVERY
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
EP3022310B1 (en) 2013-07-19 2019-10-16 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
EP3057931B1 (en) 2013-10-17 2019-03-06 Dow Global Technologies LLC Ammonium bisulfate catalyzed dehydration of beta-hydroxy acids
EP2993228B1 (en) 2014-09-02 2019-10-09 Cargill, Incorporated Production of fatty acid esters
CN105018511B (zh) * 2015-07-30 2018-08-17 中国科学院青岛生物能源与过程研究所 一种体外酶反应合成间苯三酚的方法及应用
FR3047243B1 (fr) 2016-01-29 2019-11-01 Universite De Reims Champagne-Ardenne Resine durcissable substitut aux resines phenoliques et ses applications
EP3577227A4 (en) 2017-02-02 2020-12-30 Cargill Inc. GENETICALLY MODIFIED CELLS PRODUCING C6-C10 FATTY ACID DERIVATIVES
FR3068367A1 (fr) 2017-06-30 2019-01-04 Compagnie Generale Des Etablissements Michelin Utilisation des polyketide synthases de type iii comme phloroglucinol synthases
FR3068368A1 (fr) * 2017-06-30 2019-01-04 Compagnie Generale Des Etablissements Michelin Utilisation des polyketide synthases de type iii de bacteries comme phloroglucinol synthases
FR3092339B1 (fr) * 2019-02-05 2024-04-12 Michelin & Cie Cellule, notamment levure, resistante au phloroglucinol
JP7518638B2 (ja) * 2020-03-11 2024-07-18 株式会社ブリヂストン 接着剤組成物、ゴム－有機繊維コード複合体、及びタイヤ

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2246963A (en) * 1940-04-19 1941-06-24 Western Cartridge Co Manufacture of styphnic acid
DE1694308C3 (de) * 1967-01-05 1973-11-22 Grace Gmbh, 2000 Nordersfedt Herstellen mikroporöser Bogen oder Bahnen
GB1278576A (en) * 1968-11-29 1972-06-21 Secr Defence Improvements in or relating to preparation of nitrophenols
GB1509358A (en) * 1976-07-23 1978-05-04 Mo Khim Tekh I Im Di Mendeleev Compositions based on phenol-formaldehyde novolak oligomers
US4760048A (en) * 1985-03-01 1988-07-26 Fuji Photo Film Co., Ltd. Multicolor heat-sensitive recording material
US5350576A (en) 1991-09-13 1994-09-27 Mycogen Corporation Bacillus thuringiensis isolates for controlling acarides
JP2613148B2 (ja) * 1992-02-28 1997-05-21 日本コーンスターチ株式会社 段ボール用澱粉系接着剤
US5955298A (en) * 1995-06-26 1999-09-21 The United States Of America As Represented By The Secretary Of Agriculture Sequences for production of 2,4-Diacetylphloroglucinol and methods
US6194167B1 (en) 1997-02-18 2001-02-27 Washington State University Research Foundation ω-3 fatty acid desaturase
US6277625B1 (en) * 1997-11-20 2001-08-21 The United States Of America As Represented By The Secretary Of Agriculture Transgenic strains of Pseudomonas for biocontrol of plant root diseases
PL200384B1 (pl) 1999-03-18 2008-12-31 Merck Patent Gmbh Polipeptyd blokujący adhezję płytek krwi, sposób jego otrzymywania, zastosowanie i zawierający go preparat farmaceutyczny
FR2793685B1 (fr) * 1999-05-19 2001-08-24 Promindus Actions Promotionnel Compositions pharmaceutiques, destinees a l'administration par voie orale de phloroglucinol et leur preparation
CA2272732C (en) * 1999-05-25 2008-07-29 Sylvain Simoneau Hemorrhoidal treatment composition
US20030031670A1 (en) 1999-11-08 2003-02-13 Jack R. Wands Diagnosis and treatment of malignant neoplasms
US6790639B2 (en) 2000-02-29 2004-09-14 Pfizer Inc. Mammalian osteoregulins
US6555353B2 (en) 2000-09-01 2003-04-29 E. I. Du Pont De Nemours And Company Methanotrophic carbon metabolism pathway genes and enzymes
KR101340580B1 (ko) * 2004-10-12 2013-12-11 보드 오브 트러스티즈 오브 미시건 스테이트 유니버시티 플로로글루시놀의 생합성 및 이로부터1,3-디하이드록시벤젠의 합성

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Publication number Publication date
US7943362B2 (en) 2011-05-17
US8329445B2 (en) 2012-12-11
JP2008517588A (ja) 2008-05-29
KR101340580B1 (ko) 2013-12-11
EP1799828B1 (en) 2013-05-01
US20110183391A1 (en) 2011-07-28
WO2006044290A3 (en) 2006-11-16
WO2006044290A2 (en) 2006-04-27
US20070178571A1 (en) 2007-08-02
BRPI0515994A (pt) 2008-08-19
KR20070069198A (ko) 2007-07-02
EP1799828A2 (en) 2007-06-27
WO2006044290A8 (en) 2007-05-10

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