JP5759445B2 - 病原体に対する哺乳類先天性免疫抵抗性の刺激のための組成物 - Google Patents

病原体に対する哺乳類先天性免疫抵抗性の刺激のための組成物 Download PDF

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JP5759445B2
JP5759445B2 JP2012502246A JP2012502246A JP5759445B2 JP 5759445 B2 JP5759445 B2 JP 5759445B2 JP 2012502246 A JP2012502246 A JP 2012502246A JP 2012502246 A JP2012502246 A JP 2012502246A JP 5759445 B2 JP5759445 B2 JP 5759445B2
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JP2012522001A (ja
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バートン ディッキー
バートン ディッキー
マイケル トゥビム
マイケル トゥビム
スコット エバンス
スコット エバンス
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University of Texas System
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7125—Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters
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    • A61K38/08—Peptides having 5 to 11 amino acids
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
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    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Pulmonology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
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  • Rheumatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pain & Pain Management (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
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JP2012502246A 2009-03-25 2010-03-25 病原体に対する哺乳類先天性免疫抵抗性の刺激のための組成物 Active JP5759445B2 (ja)

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US16313709P 2009-03-25 2009-03-25
US61/163,137 2009-03-25
US17924609P 2009-05-18 2009-05-18
US61/179,246 2009-05-18
PCT/US2010/028658 WO2010111485A1 (en) 2009-03-25 2010-03-25 Compositions for stimulation of mammalian innate immune resistance to pathogens

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JP2015114466A Division JP6084655B2 (ja) 2009-03-25 2015-06-05 病原体に対する哺乳類先天性免疫抵抗性の刺激のための組成物

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JP2012522001A JP2012522001A (ja) 2012-09-20
JP2012522001A5 JP2012522001A5 (enExample) 2013-04-18
JP5759445B2 true JP5759445B2 (ja) 2015-08-05

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JP2015114466A Active JP6084655B2 (ja) 2009-03-25 2015-06-05 病原体に対する哺乳類先天性免疫抵抗性の刺激のための組成物

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US (6) US8883174B2 (enExample)
EP (1) EP2411521B1 (enExample)
JP (2) JP5759445B2 (enExample)
KR (2) KR101730351B1 (enExample)
CN (3) CN103800906B (enExample)
AU (1) AU2010229835B2 (enExample)
BR (1) BRPI1009842B8 (enExample)
CA (2) CA2756412C (enExample)
ES (1) ES2534947T3 (enExample)
IL (2) IL215288A (enExample)
MX (1) MX2011010050A (enExample)
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PT (1) PT2411521E (enExample)
WO (1) WO2010111485A1 (enExample)
ZA (1) ZA201107774B (enExample)

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JP6750468B2 (ja) * 2016-11-18 2020-09-02 アイシン精機株式会社 内燃機関
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KR102747437B1 (ko) 2017-12-21 2024-12-26 악셀리아 온콜로지 피티와이 리미티드 최적화된 화합물
CN108739670A (zh) * 2018-09-04 2018-11-06 乡宁县关王庙乡新杰养羊专业合作社 一种防治羊肾炎的方法
CN114174260B (zh) 2019-06-26 2025-09-05 艾娜呼吸私人有限公司 新型分子
CN114981436A (zh) * 2020-01-10 2022-08-30 Sbi生物技术有限公司 新tlr9激动剂
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US20230338395A1 (en) * 2020-04-19 2023-10-26 Ludwig Englmeier Prophylaxis and treatment of coronavirus infection
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CN113234130A (zh) * 2021-05-24 2021-08-10 安徽医科大学第四附属医院 一种卡氏肺孢子菌重组蛋白及其制备方法与应用
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CA2756412A1 (en) 2010-09-30
EP2411521A1 (en) 2012-02-01
KR20140014358A (ko) 2014-02-06
ZA201107774B (en) 2012-07-25
MX2011010050A (es) 2011-12-14
US10722573B2 (en) 2020-07-28
US9504742B2 (en) 2016-11-29
CA3033133A1 (en) 2010-09-30
AU2010229835A1 (en) 2011-10-13
PT2411521E (pt) 2015-04-21
JP2015199747A (ja) 2015-11-12
ES2534947T3 (es) 2015-04-30
CN103800906A (zh) 2014-05-21
AU2010229835B2 (en) 2015-01-15
IL240202A0 (en) 2015-09-24
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US20250152703A1 (en) 2025-05-15
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JP6084655B2 (ja) 2017-02-22
IL215288A (en) 2015-08-31
CN105126072B (zh) 2020-05-15
CN103800906B (zh) 2017-09-22
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US9186400B2 (en) 2015-11-17
US20160074508A1 (en) 2016-03-17
CN102439153B (zh) 2015-07-22
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US8883174B2 (en) 2014-11-11
US12201684B2 (en) 2025-01-21
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WO2010111485A1 (en) 2010-09-30
US20200345842A1 (en) 2020-11-05
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BRPI1009842A2 (pt) 2017-06-06

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