JP5732471B2 - 溶媒混合物およびビタミンｄ誘導体から成る医薬品組成物または類似体 - Google Patents

溶媒混合物およびビタミンｄ誘導体から成る医薬品組成物または類似体 Download PDF

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Publication number
JP5732471B2
JP5732471B2 JP2012545092A JP2012545092A JP5732471B2 JP 5732471 B2 JP5732471 B2 JP 5732471B2 JP 2012545092 A JP2012545092 A JP 2012545092A JP 2012545092 A JP2012545092 A JP 2012545092A JP 5732471 B2 JP5732471 B2 JP 5732471B2
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composition according
composition
solvent
polyoxypropylene
calcipotriol
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JP2012545092A
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JP2013515020A5 (enExample
JP2013515020A (ja
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カーステン・ペーターソン
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Leo Pharma AS
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Leo Pharma AS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2012545092A 2009-12-22 2010-12-22 溶媒混合物およびビタミンｄ誘導体から成る医薬品組成物または類似体 Expired - Fee Related JP5732471B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DK2009000264 2009-12-22
DKPCT/DK2009/000264 2009-12-22
US29310810P 2010-01-07 2010-01-07
US61/293,108 2010-01-07
PCT/DK2010/000184 WO2011076209A2 (en) 2009-12-22 2010-12-22 Pharmaceutical composition comprising solvent mixture and a vitamin d derivative or analogue

Publications (3)

Publication Number Publication Date
JP2013515020A JP2013515020A (ja) 2013-05-02
JP2013515020A5 JP2013515020A5 (enExample) 2013-12-19
JP5732471B2 true JP5732471B2 (ja) 2015-06-10

Family

ID=43618136

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012545092A Expired - Fee Related JP5732471B2 (ja) 2009-12-22 2010-12-22 溶媒混合物およびビタミンｄ誘導体から成る医薬品組成物または類似体

Country Status (14)

Country Link
US (1) US20130023501A1 (enExample)
EP (1) EP2515866B1 (enExample)
JP (1) JP5732471B2 (enExample)
CN (1) CN102770121B (enExample)
AU (1) AU2010335656B2 (enExample)
BR (1) BR112012015437A2 (enExample)
CA (1) CA2785254A1 (enExample)
ES (1) ES2452872T3 (enExample)
IL (1) IL220517A (enExample)
MX (1) MX2012007225A (enExample)
NZ (1) NZ601001A (enExample)
RU (1) RU2559084C2 (enExample)
WO (1) WO2011076209A2 (enExample)
ZA (1) ZA201204622B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022553635A (ja) * 2019-10-25 2022-12-26 カーディオル セラピューティクス インコーポレイテッド 心臓病態の治療に使用するためのカンナビジオール組成物

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014132227A1 (en) * 2013-02-27 2014-09-04 Batt Laurie Robert Transdermal formulations
KR102486797B1 (ko) * 2016-03-09 2023-01-11 삼성전자 주식회사 전자 장치 및 전자 장치의 디스플레이 구동 방법
CN107643354B (zh) * 2016-07-22 2022-02-01 重庆华邦胜凯制药有限公司 卡泊三醇起始原料a及相关杂质的分离与测定方法
CN106265511A (zh) * 2016-08-22 2017-01-04 江苏知原药业有限公司 一种性能优异的卡泊三醇倍他米松自微乳制剂
CN106265485A (zh) * 2016-08-22 2017-01-04 江苏知原药业有限公司 一种稳定性改善的卡泊三醇组合物
CN108904445A (zh) * 2018-08-06 2018-11-30 江苏知原药业有限公司 钙泊三醇纳米悬浮液
KR102891680B1 (ko) 2020-07-28 2025-11-27 아큐티스 바이오테라퓨틱스, 인크. Jak 저해제 및 라우레스-4를 함유하는 국소 제형
MX2024007437A (es) 2021-12-15 2024-09-04 Arcutis Biotherapeutics Inc Formulaciones estables de shr0302.

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US4083974A (en) * 1977-03-07 1978-04-11 The Upjohn Company Topical steroidal anti-inflammatory preparations containing polyoxypropylene 15 stearyl ether
DE4011682A1 (de) * 1990-04-06 1991-10-10 Schering Ag 24-oxa-derivate in der vitamin d-reihe
US5194431A (en) * 1992-07-08 1993-03-16 Wisconsin Alumni Research Foundation 24-cyclopropane vitamin D derivatives
US5763426A (en) 1993-01-15 1998-06-09 Leo Pharmaceutical Products Ltd. Crystalline form of a vitamin D analogue
GB9611603D0 (en) * 1996-06-04 1996-08-07 Leo Pharm Prod Ltd Chemical compounds
US8263580B2 (en) * 1998-09-11 2012-09-11 Stiefel Research Australia Pty Ltd Vitamin formulation
US6267985B1 (en) * 1999-06-30 2001-07-31 Lipocine Inc. Clear oil-containing pharmaceutical compositions
CA2370565C (en) * 1999-04-23 2008-11-25 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) Dermally applicable vitamin d-containing pharmaceutical compositions
JP2005515996A (ja) * 2001-12-03 2005-06-02 ノバセア インコーポレイティッド 活性型ビタミンｄ化合物を含む薬学的組成物
ZA200510137B (en) 2003-07-24 2007-04-25 Leo Pharma As Novel aminobenzophenone compounds
US8741333B2 (en) * 2004-06-07 2014-06-03 Nuvo Research Inc. Compositions and methods for treating dermatitis or psoriasis
FR2871694B1 (fr) * 2004-06-17 2008-07-04 Galderma Sa Composition pharmaceutique comprenant un onguent oleagineux et deux principes actifs solubilises
KR101260236B1 (ko) 2004-12-13 2013-05-06 레오 파마 에이/에스 트리아졸 치환된 아미노벤조페논 화합물
FR2887150B1 (fr) * 2005-06-17 2007-08-03 Galderma Res & Dev Composition pharmaceutique comprenant un elastomere organopolysiloxane et un principe actif solubilise
FR2909284B1 (fr) * 2006-11-30 2012-09-21 Galderma Sa Nouvelles compositions sous forme d'onguent sans vaseline comprenant un derive de vitamine d et eventuellement un anti-inflammatoire steroidien
AU2007336538B2 (en) 2006-12-22 2012-04-05 Leo Pharma A/S Substituted acetophenones useful as PDE4 inhibitors
KR101571654B1 (ko) 2007-02-28 2015-11-25 레오 파마 에이/에스 신규한 포스포디에스테라제 억제제
US7909624B2 (en) 2007-03-26 2011-03-22 Belkin International, Inc. Carabiner universal serial bus hub
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HRP20231142T3 (hr) * 2007-04-25 2024-01-05 Eirgen Pharma Ltd. Kontrolirano oslobađanje 25-hidroksivitamina d
US20100189674A1 (en) 2007-05-11 2010-07-29 Sonneborn Inc. Petrolatum Having Silicone-Like Properties
SG172206A1 (en) 2008-12-19 2011-07-28 Leo Pharma As Triazolopyridines as phosphodiesterase inhibitors for treatment of dermal diseases

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022553635A (ja) * 2019-10-25 2022-12-26 カーディオル セラピューティクス インコーポレイテッド 心臓病態の治療に使用するためのカンナビジオール組成物

Also Published As

Publication number Publication date
CN102770121A (zh) 2012-11-07
WO2011076209A2 (en) 2011-06-30
WO2011076209A3 (en) 2012-02-23
NZ601001A (en) 2014-07-25
RU2012130411A (ru) 2014-01-27
IL220517A (en) 2016-08-31
AU2010335656A1 (en) 2012-07-19
HK1177696A1 (en) 2013-08-30
EP2515866A2 (en) 2012-10-31
AU2010335656B2 (en) 2015-05-07
EP2515866B1 (en) 2014-02-19
CA2785254A1 (en) 2011-06-30
BR112012015437A2 (pt) 2016-03-15
US20130023501A1 (en) 2013-01-24
RU2559084C2 (ru) 2015-08-10
CN102770121B (zh) 2014-10-15
JP2013515020A (ja) 2013-05-02
IL220517A0 (en) 2012-08-30
MX2012007225A (es) 2012-07-30
ES2452872T3 (es) 2014-04-03
ZA201204622B (en) 2013-09-25

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