JP5730485B2 - Mite repellent for bedding - Google Patents

Description

The present invention relates to a tick repellent for bedding.

In recent years, due to changes in the living environment, indoor dust mites such as mites, leopard mites, dust mites, claw mites, etc. have been generated indoors, causing problems such as causing allergic asthma and skin rash as well as causing discomfort. ing.
Therefore, indoor acaricides for processing bedding such as pillows, futons, cushions, etc. have been demanded, but because there are many situations where they are in direct contact with the skin, it is necessary to develop safer drugs. Therefore, the exact control method has not been established yet. Furthermore, it has been clarified that leopard mites that cause allergic asthma can cause allergies even in the corpse itself.

Against this background, a technique for preventing tick from approaching people and patients rather than killing indoor dust mites has been sought, and several proposals have been made so far. For example, JP-A-63-104905 discloses a preventive or repellent or extermination of ticks in a house containing terpenes such as α, β-pinene, α, β-terpinol, limonene and menthol. Agents are described. JP-A-6-16515 discloses plant essential oils such as vetiver oil, patchouli oil and clove oil as active ingredients of indoor mite control agents, and JP-A-2001-294506 discloses citronellal, linalool, Citral etc. are disclosed. Although these are conscious of natural products and safety, they are not suitable for use in bedding due to their strong odor and are not satisfactory for the repellent effect on indoor dust mites.

JP 63-104905 A Japanese Patent Laid-Open No. 6-16515 JP 2001-294506 A

The present invention is a tick repellent used for bedding such as pillows, futons and cushions, which has a high repellent effect on indoor dust mites, is excellent in safety against human livestock, and has no smell and is easy to use. The purpose is to provide an agent.

The present invention has been found that the following constitution has an excellent effect for achieving the above-mentioned object.
(1) A solid carrier containing green tea extract or koji extract together with p-menthane-3,8-diol as a tick repellent component is packaged with a breathable material which is a nonwoven fabric,
A tick repellent for bedding, wherein the material of the nonwoven fabric is polyester, polyethylene or polypropylene on which paper may be laminated.
(2) As the solid carrier, cellulose beads having an average particle diameter of 1 to 4 mm, an apparent specific gravity of 0.10 to 0.35 and charcoal may be blended, and the p-menthane per 1 g of beads is used. The tick repellent for bedding according to (1), wherein 50 to 250 mg of 3,8-diol is contained.

The tick repellent for bedding of the present invention has excellent repellent effect on indoor dust mites such as mite, leopard mite, dust mite, claw mite, etc. Is extremely expensive.

The mite repellent for bedding of the present invention contains p-menthane-3,8-diol as a repellent component. p-menthane-3,8-diol is a substance contained in the essential oil of lemon eucalyptus and may be a naturally derived component or a synthetic product. In p-menthane-3,8-diol, there exist a trans isomer and a cis isomer based on a steric structure, but in the present invention, a mixture of both isomers in any ratio can be used. Although this compound is known as a repellent component of repellents for flying insect pests such as mosquitoes, there has been no report on the repellent effect on indoor dust mites.

However, the present inventors diligently investigated the repellent effect of this compound on indoor dust mites, and as a result of the test, they found that the terpene compound exhibits a particularly excellent repellent effect. And since this compound is highly safe for human livestock and has a weak odor, it has been proved that it is extremely useful for this application, and the present invention has been completed.

In the present invention, various components are added to the above-mentioned p-menthane-3,8-diol to prepare a repellent composition, which is applied to various forms of mite repellent for bedding. The blending amount of p-menthane-3,8-diol with respect to the total amount of the mite repellent for bedding varies depending on the form of the mite repellent for bedding, but is set to about 0.02 to 1.0 g per mite repellent. In the case of pillows and cushions, it is easy to use one piece. If it is less than 0.02 g, the repellent effect is not sufficient, while if it exceeds 1.0 g, it is not practical, such as a sticky feeling. In the case of a large bedding such as a futon or mat, the number of applications may be increased as necessary.

The mite repellent for bedding of the present invention preferably contains a plant-derived deodorant component together with the p-menthane-3,8-diol. As such a plant extract, it is appropriate to use one or more selected from the family Gramineae, Camelliaaceae, Ginkgoaceae, Oleaceae, Mulberry, Citrus, Kintranoaceae, Oysteraceae, and extract green tea. The product and the cocoon extract are typical. In addition, about 0.002-0.1 time amount is sufficient with respect to p-menthane-3,8-diol as the compounding quantity of a plant-derived deodorant component.
Known as a component of a plant extract, for example, polyphenols are known as deodorant components, but act as potentiating components of p-menthane-3,8-diol in the mite repellent for bedding of the present invention. The knowledge is completely new. The reason for this is presumed to have some interaction when the repellent component evaporates.

In the present invention, liquid, gel, solid, etc. repellent compositions prepared in accordance with the needs of the use scene are applied to various forms of mite repellents for bedding.
In preparing a liquid repellent composition, water, alcohol solvents such as ethanol and isopropanol, glycol solvents such as 1,3-butylene glycol, propylene glycol and dipropylene glycol, diethylene glycol monobutyl ether, propylene Various solvents such as glycol ether solvents such as glycol monomethyl ether, aliphatic hydrocarbon solvents, and surfactants (solubilizers) are used as appropriate.
Surfactants include polyoxyethylene hydrogenated castor oil, polyoxyethylene higher alkyl ether (polyoxyethylene lauryl ether, polyoxyethylene oleyl ether), polyoxyethylene higher fatty acid ester, polyoxyethylene polyoxypropylene alkyl ether, etc. Nonionic surfactants and higher alkylamine oxide surfactants such as laurylamine oxide, stearylamine oxide, amidopropyldimethylamine oxide lauryl, and the like can be exemplified.

In addition, an antibacterial component, a sterilizing component, an antifungal component, a stabilizer, a pH adjuster, a colorant, and the like may be appropriately blended, or, for example, green leaf alcohol or green leaf aldehyde called “green fragrance” It can be added to give a relaxing effect and promote sleep.
Further, examples of the gelling agent used for preparing the gel-like body include carrageenan, xanthan gum, gellan gum, gelatin, aluminum octylate, 12-hydroxystearic acid and the like.

The mite repellent for bedding of the present invention is manufactured by packaging a material obtained by impregnating or holding the repellent composition with a breathable material. Then, such a mite repellent may be placed under or near a pillow or cushion, or a futon or mat, and the repellent component may be volatilized from the solid carrier. Solid carriers include fiber carriers such as pulp, linter and rayon, beads or foam made of cellulose (regenerated cellulose), inorganic porous carriers such as silicate, silica and zeolite, sublimable carriers such as trioxane and adamantane, etc. Can be given. Above all, cellulose beads having an average particle diameter of 1 to 4 mm and an apparent specific gravity of about 0.10 to 0.35 are preferable, and a deodorizing effect can be further imparted by using a mixture of charcoal and a repellent effect. Since it was recognized that it contributes also to enhancement, it is more preferable. In addition, what is necessary is just to determine the quantity of the charcoal mix | blended suitably in the range of 5-70 mass% with respect to the bead made from cellulose.
For example, about 50 to 250 mg of the p-menthane-3,8-diol is contained per gram of cellulose beads containing 40 to 60% by mass of charcoal, and is stored in a package made of a breathable material. If constituted, a useful and highly practical mite repellent for bedding can be obtained.

Examples of the package using a breathable material include a non-woven bag, a cotton bag, a net case, a perforated plastic container, etc. Among these, the non-woven bag is easy to use. The material of the nonwoven fabric is not particularly limited, and examples thereof include polyester (PET), polyethylene (PE), polypropylene (PP), polyamide, polylactic acid, rayon and the like, and these may be a single fiber, Alternatively, a laminate or a blended product such as polyester or polypropylene / rayon on which paper is laminated may be used. Of these, polyester, polyethylene, and polypropylene on which paper is laminated, which can partially adsorb the p-menthane-3,8-diol and secondarily adjust its volatilization amount, are preferable.
In addition, the shape and configuration of the non-woven bag can also be determined as appropriate. For example, both sides may be made of a breathable non-woven fabric of the above material, or one side is a breathable non-woven fabric of the above material and the other side is small. What stuck together the plastic film which may have many holes may be used.
On the other hand, if a plastic container with poor flexibility is used, there is a risk of damaging bedding and the like, so the usage scene is limited.

The mite repellent for bedding of the present invention thus obtained is installed under or near a pillow or cushion, or a futon or mat, and the repellent component is volatilized from the solid carrier through the breathable material, Not only indoor dust mites such as mite, leopard mite, dust mite, claw mite, but also various kinds of weevil, cutlet worm, chatter beetle, beetle, cockroach, ant, mosquito, moth, chironomid, fly, butterfly, moth, etc. It has a practical repellent effect over a long period of 1 to 2 months against pests. In addition, p-menthane-3,8-diol used as a repellent component in the present invention has a very weak odor compared to general herbal essential oils and the like, and its practicality is extremely high because there is almost no odor transfer to bedding and the like. .
Moreover, when a plant-derived deodorant component is blended with p-menthane-3,8-diol, not only the deodorizing effect is imparted, but also the repellent effect of p-menthane-3,8-diol is enhanced. In addition, by using cellulose beads containing charcoal as a solid carrier, the deodorizing effect and the repellent effect are further improved, and the tick repellent for bedding of the present invention is more useful. An agent can be obtained.

Next, the tick repellent for bedding of the present invention will be described in more detail based on specific examples.

About 4 g of charcoal-blended cellulose beads having an average particle size of 3 mm (charcoal content: 50 mass%), 300 mg of p-menthane-3,8-diol, 6 mg of green tea extract, and 100 mg of propylene glycol are contained, The beads were housed in a bag (6 × 9 cm) made of a paper-laminated polyester nonwoven fabric having air permeability on both sides to prepare a tick repellent for bedding of the present invention.
When this bedding mite repellent was placed under a pillow and used, the material was not hard and easy to use. Further, for about one month, indoor dust mites such as acarid mites, leopard mites, dust mites, claw mites and the like were not brought close to each other, and a deodorizing effect was imparted, which was extremely practical.

According to Example 1, various bedding repellents for bedding shown in Table 1 were prepared. In the table, p-menthane-3,8-diol was referred to as this component, and as the solid carrier, pulp / linter mats and calcium silicate beads were used in addition to cellulose beads.

The following performance tests were conducted for each bedding mite repellent. The results are shown in Table 2.
1. Measurement of volatilization amount of mite repellent component Mite repellent for bedding was wrapped with a wool blanket, 4 kg of weight was placed on it and allowed to stand at room temperature. After 5 days, the mite repellent component remaining in the mite repellent for bedding was analyzed to determine the volatilization amount per day. (The subsequent volatilization amount is not shown as data, but the volatilization amount per day was substantially the same until the volatilization of the repellent component was completed.)
2. Tick repellent efficacy test A medium containing about 100,000 test leopard mites on a 50 cm square cotton cloth surface was evenly spread. The mite repellent for bedding shown in Table 1 was placed on the upper part of the pillow, covered with a pillow cover, 1 g of the invitation medium was spread on the surface, and then left on the center of the cotton cloth. Similarly, it was set as the no-treatment area using the pillow which does not install the mite repellent for bedding.
After 24 hours, the number of mites that had entered the pillow cover was counted, and the repelling rate was calculated according to the following formula.

Repelling rate (%) = [number of invading ticks in untreated area−number of invading ticks in treated area] / number of invading ticks in untreated area × 100
3. Odor transfer test After measuring the volatilization amount of the mite repellent component (after 5 days), a sensory test was conducted by 10 monitors on how much the odor was transferred to the wool blanket. The results are shown by the following criteria.
○: One person who feels almost no smell, △: 2-5 people smell,
X: 6 or more people smell clearly.

As a result of the test, the mite repellent for bedding of the present invention shows an excellent repellent effect against the mushroom mite, based on the action of p-menthan-3,8-diol blended as a mite repellent component, and the odor to textile products There was no change. It was also clarified that the repellent efficacy was improved when plant-derived deodorant ingredients such as green tea extract and koji extract were blended or when charcoal-blended cellulose beads were used as the solid carrier.
On the other hand, as shown in Comparative Example 1 and Comparative Example 2, citronellal of the same terpene compound and vetiver oil of natural essential oil have insufficient repellency and a strong odor, and as a tick repellent component for bedding It was inappropriate.

The present invention can be used not only in the mite repellent for bedding but also in a wide range of pest repellent fields.

Claims (2)

A solid carrier containing green tea extract or koji extract together with p-menthane-3,8-diol as a tick repellent component is packaged with a breathable material that is a nonwoven fabric,
A tick repellent for bedding, wherein the material of the nonwoven fabric is polyester, polyethylene or polypropylene on which paper may be laminated. As the solid support, cellulose beads having an average particle diameter of 1 to 4 mm, an apparent specific gravity of 0.10 to 0.35 and charcoal may be used, and the p-menthane-3,8 per 1 g of beads is used. The ticks repellent for bedding according to claim 1, wherein the diol is contained in an amount of 50 to 250 mg.