JP5707408B2 - 顕微鏡画像を形成するための方法および顕微鏡 - Google Patents
顕微鏡画像を形成するための方法および顕微鏡 Download PDFInfo
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- JP5707408B2 JP5707408B2 JP2012531254A JP2012531254A JP5707408B2 JP 5707408 B2 JP5707408 B2 JP 5707408B2 JP 2012531254 A JP2012531254 A JP 2012531254A JP 2012531254 A JP2012531254 A JP 2012531254A JP 5707408 B2 JP5707408 B2 JP 5707408B2
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- 238000005286 illumination Methods 0.000 claims description 105
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
- G01N21/6458—Fluorescence microscopy
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/06—Means for illuminating specimens
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
- G02B21/365—Control or image processing arrangements for digital or video microscopes
- G02B21/367—Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
- G02B27/56—Optics using evanescent waves, i.e. inhomogeneous waves
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
- G02B27/58—Optics for apodization or superresolution; Optical synthetic aperture systems
-
- H—ELECTRICITY
- H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
- H10F—INORGANIC SEMICONDUCTOR DEVICES SENSITIVE TO INFRARED RADIATION, LIGHT, ELECTROMAGNETIC RADIATION OF SHORTER WAVELENGTH OR CORPUSCULAR RADIATION
- H10F39/00—Integrated devices, or assemblies of multiple devices, comprising at least one element covered by group H10F30/00, e.g. radiation detectors comprising photodiode arrays
- H10F39/10—Integrated devices
- H10F39/12—Image sensors
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- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Multimedia (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Microscoopes, Condenser (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102009043747A DE102009043747A1 (de) | 2009-09-30 | 2009-09-30 | Verfahren zur Erzeugung eines Mikroskopbildes und Mikroskop |
| DE102009043747.9 | 2009-09-30 | ||
| PCT/EP2010/005295 WO2011038817A1 (de) | 2009-09-30 | 2010-08-28 | Verfahren zur erzeugung eines mikroskopbildes und mikroskop |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2013506163A JP2013506163A (ja) | 2013-02-21 |
| JP2013506163A6 JP2013506163A6 (ja) | 2013-05-02 |
| JP2013506163A5 JP2013506163A5 (enExample) | 2013-10-10 |
| JP5707408B2 true JP5707408B2 (ja) | 2015-04-30 |
Family
ID=42761248
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012531254A Expired - Fee Related JP5707408B2 (ja) | 2009-09-30 | 2010-09-29 | 顕微鏡画像を形成するための方法および顕微鏡 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9588045B2 (enExample) |
| EP (1) | EP2483732B1 (enExample) |
| JP (1) | JP5707408B2 (enExample) |
| DE (1) | DE102009043747A1 (enExample) |
| WO (1) | WO2011038817A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102009043747A1 (de) | 2009-09-30 | 2011-03-31 | Carl Zeiss Microlmaging Gmbh | Verfahren zur Erzeugung eines Mikroskopbildes und Mikroskop |
| DE102010026205A1 (de) * | 2010-07-06 | 2012-01-12 | Carl Zeiss Microlmaging Gmbh | Mikroskop, insbesondere Fluoreszenzmikroskop, dichroitischer Strahlteiler und dessen Verwendung |
| DE102011077269A1 (de) * | 2011-06-09 | 2012-12-13 | Carl Zeiss Microimaging Gmbh | Hochauflösende Lumineszenzmikroskopie |
| WO2014017067A1 (ja) * | 2012-07-27 | 2014-01-30 | 株式会社ニコン | 構造化照明装置及び構造化照明顕微鏡 |
| GB201215771D0 (en) * | 2012-09-04 | 2012-10-17 | Univ Nottingham | Monitoring and/or characterising biological or chemicl material |
| EP2801854B1 (en) * | 2013-05-10 | 2017-07-19 | Ruprecht-Karls-Universität Heidelberg | Method and apparatus for combination of localization microscopy and structured illumination microscopy |
| WO2015164378A1 (en) | 2014-04-22 | 2015-10-29 | Q-State Biosciences, Inc. | Analysis of compounds for pain and sensory disorders |
| JP2016181643A (ja) * | 2015-03-25 | 2016-10-13 | 株式会社アマダホールディングス | 半導体レーザ発振器 |
| US10288863B2 (en) | 2015-05-21 | 2019-05-14 | Q-State Biosciences, Inc. | Optogenetics microscope |
| KR20170042432A (ko) * | 2015-10-08 | 2017-04-19 | 삼성전자주식회사 | 포토레지스트 패턴의 검사 방법 |
| JP7389487B2 (ja) * | 2017-09-18 | 2023-11-30 | アポロ メディカル オプティクス，エルティーディー． | 干渉撮像装置およびその用途 |
| DE102018108657B4 (de) * | 2018-04-12 | 2024-03-28 | Jenoptik Optical Systems Gmbh | Vorrichtung zur Aufnahme wenigstens eines mikroskopischen Bildes und Verfahren zur Aufnahme eines mikroskopischen Bildes |
| US10901202B2 (en) * | 2018-09-19 | 2021-01-26 | Illumina, Inc. | Structured illumination of a sample |
| FR3096146B1 (fr) | 2019-05-16 | 2022-07-29 | Univ Grenoble Alpes | Dispositif de creation d’un champ evanescent a motifs sur une surface et procede associe |
| GB201907953D0 (en) | 2019-06-04 | 2019-07-17 | Smi Drug Discovery Ltd | An optical microscope |
| DE102019118003B3 (de) * | 2019-07-03 | 2020-10-22 | Leibniz-Institut für Photonische Technologien e. V. | Mikroskopieanordnung und Mikroskopieverfahren für eine großflächige, hochauflösende chirale Bildgebung sowie deren Verwendung |
| KR102258893B1 (ko) * | 2019-11-28 | 2021-05-31 | 재단법인대구경북과학기술원 | 내시현미경의 수직 분해능 최적화 장치, 최적화 광학 시스템 및 최적화 방법 |
| CN112326665B (zh) * | 2020-09-28 | 2023-12-19 | 之江实验室 | 一种基于空间分步式移频照明的缺陷检测系统 |
| US20230314327A1 (en) * | 2022-04-04 | 2023-10-05 | 10X Genomics, Inc. | Systems and methods for nearly isotropic optical resolution using tilted structured illumination microscopy |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5867604A (en) | 1995-08-03 | 1999-02-02 | Ben-Levy; Meir | Imaging measurement system |
| DE19758745C5 (de) | 1997-01-27 | 2008-09-25 | Carl Zeiss Jena Gmbh | Laser-Scanning-Mikroskop |
| DE19908883A1 (de) | 1999-03-02 | 2000-09-07 | Rainer Heintzmann | Verfahren zur Erhöhung der Auflösung optischer Abbildung |
| US6255642B1 (en) * | 1999-06-23 | 2001-07-03 | Massachusetts Institute Of Technology | Standing wave total internal reflection imaging |
| JP4414722B2 (ja) * | 2003-10-15 | 2010-02-10 | オリンパス株式会社 | レーザー顕微鏡 |
| EP1741485A1 (en) * | 2004-03-27 | 2007-01-10 | Niigata Technology Licensing Organization | Photoreactive thin film processing method and photoreactive thin film processing apparatus |
| DE102004034998A1 (de) * | 2004-07-16 | 2006-02-02 | Carl Zeiss Jena Gmbh | Lichtrastermikroskop mit bewegter Lochscheibe und Verwendung |
| DE102004034983A1 (de) | 2004-07-16 | 2006-02-02 | Carl Zeiss Jena Gmbh | Lichtrastermikroskop |
| EP2453239B1 (en) | 2005-05-23 | 2017-04-26 | Harald F. Hess | Optical microscopy with transformable optical labels |
| US7485875B2 (en) * | 2005-07-22 | 2009-02-03 | Carl Zeiss Microimaging Gmbh | Resolution-enhanced luminescence microscopy |
| GB0707433D0 (en) * | 2007-04-18 | 2007-05-23 | Stfc Science & Technology | Fluorescence measurement |
| DE102008009216A1 (de) * | 2008-02-13 | 2009-08-20 | Carl Zeiss Microimaging Gmbh | Vorrichtung und Verfahren zum räumlich hochauflösenden Abbilden einer Struktur einer Probe |
| WO2009142758A1 (en) * | 2008-05-23 | 2009-11-26 | Spectral Image, Inc. | Systems and methods for hyperspectral medical imaging |
| US8019136B2 (en) * | 2008-12-03 | 2011-09-13 | Academia Sinica | Optical sectioning microscopy |
| DE102009043747A1 (de) | 2009-09-30 | 2011-03-31 | Carl Zeiss Microlmaging Gmbh | Verfahren zur Erzeugung eines Mikroskopbildes und Mikroskop |
-
2009
- 2009-09-30 DE DE102009043747A patent/DE102009043747A1/de not_active Ceased
-
2010
- 2010-08-28 EP EP10749799.2A patent/EP2483732B1/de active Active
- 2010-08-28 WO PCT/EP2010/005295 patent/WO2011038817A1/de not_active Ceased
- 2010-09-29 JP JP2012531254A patent/JP5707408B2/ja not_active Expired - Fee Related
-
2012
- 2012-03-30 US US13/499,328 patent/US9588045B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2011038817A1 (de) | 2011-04-07 |
| JP2013506163A (ja) | 2013-02-21 |
| EP2483732B1 (de) | 2023-06-21 |
| US20130068967A1 (en) | 2013-03-21 |
| US9588045B2 (en) | 2017-03-07 |
| DE102009043747A1 (de) | 2011-03-31 |
| EP2483732A1 (de) | 2012-08-08 |
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