JP5705432B2 - 光学アッセイシステム - Google Patents
光学アッセイシステム Download PDFInfo
- Publication number
- JP5705432B2 JP5705432B2 JP2009501380A JP2009501380A JP5705432B2 JP 5705432 B2 JP5705432 B2 JP 5705432B2 JP 2009501380 A JP2009501380 A JP 2009501380A JP 2009501380 A JP2009501380 A JP 2009501380A JP 5705432 B2 JP5705432 B2 JP 5705432B2
- Authority
- JP
- Japan
- Prior art keywords
- substrate
- fluorescence
- light
- total internal
- internal reflection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N2021/6463—Optics
- G01N2021/6465—Angular discrimination
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Optics & Photonics (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0600642-3 | 2006-03-22 | ||
| SE0600642A SE529711C2 (sv) | 2006-03-22 | 2006-03-22 | Fluorescensläsare |
| PCT/SE2007/000275 WO2007108752A1 (en) | 2006-03-22 | 2007-03-21 | Fluorescence reader |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009530637A JP2009530637A (ja) | 2009-08-27 |
| JP2009530637A5 JP2009530637A5 (enExample) | 2010-04-22 |
| JP5705432B2 true JP5705432B2 (ja) | 2015-04-22 |
Family
ID=38522714
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009501380A Expired - Fee Related JP5705432B2 (ja) | 2006-03-22 | 2007-03-21 | 光学アッセイシステム |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8691153B2 (enExample) |
| EP (1) | EP1996922B1 (enExample) |
| JP (1) | JP5705432B2 (enExample) |
| CN (2) | CN101405594B (enExample) |
| AU (1) | AU2007227809B2 (enExample) |
| BR (1) | BRPI0709018A2 (enExample) |
| SE (1) | SE529711C2 (enExample) |
| WO (1) | WO2007108752A1 (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE529711C2 (sv) * | 2006-03-22 | 2007-11-06 | Aamic Ab | Fluorescensläsare |
| CA2832494C (en) | 2011-04-06 | 2019-11-26 | Ortho-Clinical Diagnostics, Inc. | Assay device having rhombus-shaped projections |
| JP5815123B2 (ja) * | 2011-05-05 | 2015-11-17 | イー・エム・デイー・ミリポア・コーポレイシヨン | 毛細管ベースのフローサイトメトリーにおける集光効率を高めるための装置及び方法 |
| US9642568B2 (en) * | 2011-09-06 | 2017-05-09 | Medtronic Minimed, Inc. | Orthogonally redundant sensor systems and methods |
| WO2013109821A1 (en) | 2012-01-20 | 2013-07-25 | Ortho-Clinical Diagnostics, Inc. | Assay device having multiplexing |
| KR20130085994A (ko) | 2012-01-20 | 2013-07-30 | 오르토-클리니칼 다이아그노스틱스, 인코포레이티드 | 다수의 시약 셀을 갖는 분석 장치 |
| US20130210036A1 (en) | 2012-01-20 | 2013-08-15 | Ortho-Clinical Diagnostics, Inc. | Controlling Fluid Flow Through An Assay Device |
| CN103212455B (zh) | 2012-01-20 | 2016-12-28 | 奥索临床诊断有限公司 | 在角附近具有均匀流的测定装置 |
| BR102013001324A2 (pt) | 2012-01-20 | 2015-07-28 | Ortho Clinical Diagnostics Inc | Dispositivo de ensaio tendo tamanho de amostra controlável e método para controlar o tamanho da amostra em um dispositivo de ensaio |
| EP2888277A4 (en) | 2012-08-21 | 2016-05-18 | Ortho Clinical Diagnostics Inc | ANTIBODIES AGAINST PALIPERIDONE AND USE THEREOF |
| JP6270845B2 (ja) | 2012-08-21 | 2018-01-31 | ヤンセン ファーマシューティカ エヌ.ベー. | アリピプラゾールに対する抗体及びその使用 |
| PL2888592T3 (pl) | 2012-08-21 | 2018-03-30 | Janssen Pharmaceutica Nv | Przeciwciała względem kwetiapiny i ich zastosowania |
| CA2882489A1 (en) | 2012-08-21 | 2014-02-27 | Ortho-Clinical Diagnostics, Inc. | Antibodies to paliperidone haptens and use thereof |
| WO2014031662A2 (en) | 2012-08-21 | 2014-02-27 | Ortho-Clinical Diagnostics, Inc | Antibodies to olanzapine and use thereof |
| CN104736564B (zh) | 2012-08-21 | 2019-02-05 | 詹森药业有限公司 | 喹硫平半抗原的抗体及其用途 |
| CA2882595C (en) | 2012-08-21 | 2019-06-04 | Ortho-Clinical Diagnostics, Inc. | Antibodies to olanzapine haptens and use thereof |
| PT3321254T (pt) | 2012-08-21 | 2020-10-20 | Janssen Pharmaceutica Nv | Haptenos de aripiprazol e seu uso em imunoensaios |
| PT2888593T (pt) | 2012-08-21 | 2018-12-12 | Janssen Pharmaceutica Nv | Anticorpos contra risperidona e utilizações dos mesmos |
| PT2888284T (pt) | 2012-08-21 | 2022-11-18 | Janssen Pharmaceutica Nv | Anticorpos dirigidos contra haptenos de risperidona e a sua utilização |
| CN110054694B (zh) | 2012-08-21 | 2024-02-20 | 詹森药业有限公司 | 阿立哌唑半抗原的抗体及其用途 |
| EP2920591A4 (en) | 2012-11-15 | 2016-10-19 | Ortho Clinical Diagnostics Inc | CALIBRATION ASSAYS WITH RESPONSE TIME USE |
| EP2811301B1 (en) | 2012-11-15 | 2017-05-10 | Ortho-Clinical Diagnostics, Inc. | Quality/process control of a lateral flow assay device based on flow monitoring |
| CA2841692C (en) | 2013-02-12 | 2023-08-22 | Zhong Ding | Reagent zone deposition pattern |
| FI128503B (en) | 2013-02-27 | 2020-06-30 | Teknologian Tutkimuskeskus Vtt Oy | Sample plate and assay procedure |
| EP2777499B1 (en) | 2013-03-15 | 2015-09-16 | Ortho-Clinical Diagnostics Inc | Rotatable fluid sample collection device |
| EP2778679B1 (en) | 2013-03-15 | 2017-09-27 | Ortho-Clinical Diagnostics, Inc. | Rotable disk-shaped fluid sample collection device |
| CN105980842B (zh) | 2013-12-06 | 2019-12-17 | 奥索临床诊断有限公司 | 具有清洗口的测定装置 |
| US9903858B2 (en) | 2014-07-23 | 2018-02-27 | Ortho-Clinical Diagnostics, Inc. | Multiplexing with single sample metering event to increase throughput |
| US11033896B2 (en) | 2014-08-08 | 2021-06-15 | Ortho-Clinical Diagnostics, Inc. | Lateral-flow assay device with filtration flow control |
| US10071373B2 (en) | 2014-08-08 | 2018-09-11 | Ortho-Clinical Diagnostics, Inc. | Lateral-flow assay device having flow constrictions |
| KR101621050B1 (ko) * | 2014-10-23 | 2016-05-13 | 주식회사 이뮨메드 | 의료용 진단 키트의 형광리더기 |
| AU2016264112A1 (en) | 2015-05-19 | 2017-11-16 | Ortho-Clinical Diagnostics, Inc. | Method of improving liquid sample flow in assay device |
| WO2017106501A1 (en) | 2015-12-17 | 2017-06-22 | Janssen Pharmaceutica Nv | Antibodies to risperidone and use thereof |
| JP6994461B2 (ja) | 2015-12-17 | 2022-02-04 | ヤンセン ファーマシューティカ エヌ.ベー. | クエチアピンに対する抗体及びその使用 |
| CN107242860B (zh) * | 2017-07-25 | 2021-01-19 | 京东方科技集团股份有限公司 | 荧光分子层析成像系统及方法 |
| EP3460456B1 (en) * | 2017-09-20 | 2020-08-26 | IMEC vzw | A biosensor system for detecting supercritical angle fluorescent light |
| JP7106217B2 (ja) * | 2018-08-22 | 2022-07-26 | 株式会社ディスコ | ファセット領域の検出方法及び検出装置 |
| BR112021017166A2 (pt) * | 2019-03-01 | 2021-11-09 | Vidya Holdings Ltd | Cartucho de ensaio para detectar um componente alvo em um fluido, e, método para fabricar um arranjo de cartuchos de ensaio |
| EP3705875B1 (en) | 2019-03-05 | 2022-11-30 | IMEC vzw | An apparatus and method for detecting photoluminescent light emitted from a sample |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB965084A (en) * | 1959-04-17 | 1964-07-29 | Lumalampan Ab | Improvements in or relating to an electroluminescent device |
| US3593055A (en) * | 1969-04-16 | 1971-07-13 | Bell Telephone Labor Inc | Electro-luminescent device |
| US3973129A (en) * | 1975-01-10 | 1976-08-03 | Bell Telephone Laboratories, Incorporated | Fluorimetric apparatus and method for analysis of body fluid |
| EP0075353B1 (en) * | 1981-09-18 | 1987-08-19 | Battelle Memorial Institute | Method and apparatus for the determination of species in solution with an optical wave-guide |
| US4956150A (en) * | 1985-11-27 | 1990-09-11 | Alerchek | Disposable microtiter stick |
| US5158720A (en) * | 1985-12-09 | 1992-10-27 | Mcdonnell Douglas Corporation | Method and system for continuous in situ monitoring of viscosity |
| CA1321488C (en) * | 1987-08-22 | 1993-08-24 | Martin Francis Finlan | Biological sensors |
| GB8827853D0 (en) * | 1988-11-29 | 1988-12-29 | Ares Serono Res & Dev Ltd | Sensor for optical assay |
| US6767510B1 (en) | 1992-05-21 | 2004-07-27 | Biosite, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membranes |
| US6905882B2 (en) | 1992-05-21 | 2005-06-14 | Biosite, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membranes |
| US5885527A (en) * | 1992-05-21 | 1999-03-23 | Biosite Diagnostics, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membrances |
| US6143576A (en) | 1992-05-21 | 2000-11-07 | Biosite Diagnostics, Inc. | Non-porous diagnostic devices for the controlled movement of reagents |
| US6156270A (en) | 1992-05-21 | 2000-12-05 | Biosite Diagnostics, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membranes |
| JP3326708B2 (ja) | 1993-08-31 | 2002-09-24 | 日水製薬株式会社 | 光学的測定装置およびその方法 |
| JPH07199236A (ja) * | 1993-12-28 | 1995-08-04 | Fujitsu Ltd | 光スイッチ及び光分配器 |
| US5399499A (en) * | 1994-05-13 | 1995-03-21 | Eastman Kodak Company | Method of using multiwavelength upconversion for sample element interrogation in medical diagnostic equipment |
| JPH07318481A (ja) * | 1994-05-25 | 1995-12-08 | Daikin Ind Ltd | 光学的測定方法およびその装置 |
| PL317379A1 (en) * | 1994-05-27 | 1997-04-01 | Ciba Geigy Ag | Supercritically excited luminescence detecting process |
| EP0736767A1 (de) * | 1995-04-07 | 1996-10-09 | Ciba-Geigy Ag | Optische Detektionsvorrichtung für analytische Messungen an chemischen Substanzen |
| DK0918984T3 (da) * | 1996-08-16 | 2001-10-22 | Zeptosens Ag | Optisk detektionsanordning |
| US6391265B1 (en) | 1996-08-26 | 2002-05-21 | Biosite Diagnostics, Inc. | Devices incorporating filters for filtering fluid samples |
| EP1012580B1 (de) * | 1997-09-10 | 2004-06-23 | Artificial Sensing Instruments ASI AG | Optischer sensor und optisches verfahren zur charakterisierung einer chemischen und/oder biochemischen substanz |
| AU2924399A (en) * | 1998-02-05 | 1999-08-23 | Novartis Ag | Method and device for measuring luminescence |
| DE19810615A1 (de) | 1998-03-12 | 1999-09-16 | Thomas Ruckstuhl | Optische Anordnung zum Erfassen von Licht |
| US6330464B1 (en) * | 1998-08-26 | 2001-12-11 | Sensors For Medicine & Science | Optical-based sensing devices |
| EP1055925B1 (en) * | 1999-05-28 | 2010-09-08 | Yokogawa Electric Corporation | Biochip reader |
| AU6834700A (en) * | 1999-08-13 | 2001-03-13 | Zeptosens Ag | Device and method for determining multiple analytes |
| AU4139101A (en) | 1999-12-03 | 2001-06-12 | Cree Lighting Company | Enhanced light extraction in leds through the use of internal and external optical elements |
| WO2001057501A1 (en) | 2000-02-03 | 2001-08-09 | Alpha Innotech Corporation | Improved microarray reader |
| US20020093654A1 (en) * | 2000-07-11 | 2002-07-18 | Lieberman Robert A. | Apparatus and method for imaging |
| US6905816B2 (en) * | 2000-11-27 | 2005-06-14 | Intelligent Medical Devices, Inc. | Clinically intelligent diagnostic devices and methods |
| US20040126767A1 (en) | 2002-12-27 | 2004-07-01 | Biosite Incorporated | Method and system for disease detection using marker combinations |
| WO2003060446A1 (en) | 2002-01-12 | 2003-07-24 | Maven Technologies, Llc | Apparatus and method for imaging |
| KR20030064298A (ko) * | 2002-01-23 | 2003-07-31 | 가부시키가이샤 히다치 고쿠사이 덴키 | 형광체 검사 방법 및 형광체 검사 장치 |
| US6867420B2 (en) * | 2002-06-03 | 2005-03-15 | The Regents Of The University Of California | Solid-state detector and optical system for microchip analyzers |
| JP4193421B2 (ja) * | 2002-06-06 | 2008-12-10 | ソニー株式会社 | バイオアッセイ装置及びその製造方法、並びにバイオアッセイ方法 |
| SE0201738D0 (sv) | 2002-06-07 | 2002-06-07 | Aamic Ab | Micro-fluid structures |
| JP4480130B2 (ja) * | 2003-12-16 | 2010-06-16 | キヤノン株式会社 | 光学分析装置 |
| KR100568298B1 (ko) * | 2004-03-30 | 2006-04-05 | 삼성전기주식회사 | 외부양자효율이 개선된 질화물 반도체 및 그 제조방법 |
| SE529711C2 (sv) * | 2006-03-22 | 2007-11-06 | Aamic Ab | Fluorescensläsare |
-
2006
- 2006-03-22 SE SE0600642A patent/SE529711C2/sv not_active IP Right Cessation
-
2007
- 2007-03-21 JP JP2009501380A patent/JP5705432B2/ja not_active Expired - Fee Related
- 2007-03-21 CN CN2007800096888A patent/CN101405594B/zh active Active
- 2007-03-21 WO PCT/SE2007/000275 patent/WO2007108752A1/en not_active Ceased
- 2007-03-21 EP EP07716079.4A patent/EP1996922B1/en active Active
- 2007-03-21 CN CN201210123087.2A patent/CN102636469B/zh active Active
- 2007-03-21 AU AU2007227809A patent/AU2007227809B2/en not_active Ceased
- 2007-03-21 BR BRPI0709018-8A patent/BRPI0709018A2/pt not_active Application Discontinuation
- 2007-03-22 US US11/726,973 patent/US8691153B2/en active Active
-
2014
- 2014-03-31 US US14/230,926 patent/US9279768B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP1996922A4 (en) | 2012-10-24 |
| WO2007108752A1 (en) | 2007-09-27 |
| BRPI0709018A2 (pt) | 2011-06-21 |
| US20070231883A1 (en) | 2007-10-04 |
| SE0600642L (sv) | 2007-09-23 |
| SE529711C2 (sv) | 2007-11-06 |
| US20140212984A1 (en) | 2014-07-31 |
| AU2007227809A1 (en) | 2007-09-27 |
| EP1996922B1 (en) | 2018-11-21 |
| JP2009530637A (ja) | 2009-08-27 |
| AU2007227809B2 (en) | 2012-10-04 |
| CN102636469B (zh) | 2016-07-06 |
| CN102636469A (zh) | 2012-08-15 |
| US9279768B2 (en) | 2016-03-08 |
| CN101405594B (zh) | 2012-06-27 |
| EP1996922A1 (en) | 2008-12-03 |
| CN101405594A (zh) | 2009-04-08 |
| US8691153B2 (en) | 2014-04-08 |
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