JP5702384B2 - 中空マイクロニードルアレイ - Google Patents
中空マイクロニードルアレイ Download PDFInfo
- Publication number
- JP5702384B2 JP5702384B2 JP2012522974A JP2012522974A JP5702384B2 JP 5702384 B2 JP5702384 B2 JP 5702384B2 JP 2012522974 A JP2012522974 A JP 2012522974A JP 2012522974 A JP2012522974 A JP 2012522974A JP 5702384 B2 JP5702384 B2 JP 5702384B2
- Authority
- JP
- Japan
- Prior art keywords
- fluid
- reservoir
- applicator
- stored energy
- energy device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/1454—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons spring-actuated, e.g. by a clockwork
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
- A61M2005/14252—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M2005/14506—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons mechanically driven, e.g. spring or clockwork
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0046—Solid microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0061—Methods for using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
- A61M5/3015—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules for injecting a dose of particles in form of powdered drug, e.g. mounted on a rupturable membrane and accelerated by a gaseous shock wave or supersonic gas flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
- A61M5/425—Protruding skin to facilitate piercing, e.g. vacuum cylinders, vein immobilising means
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Medical Informatics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicinal Preparation (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23034709P | 2009-07-31 | 2009-07-31 | |
| US61/230,347 | 2009-07-31 | ||
| PCT/US2010/043414 WO2011014514A1 (en) | 2009-07-31 | 2010-07-27 | Hollow microneedle arrays |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013500773A JP2013500773A (ja) | 2013-01-10 |
| JP2013500773A5 JP2013500773A5 (enExample) | 2013-09-12 |
| JP5702384B2 true JP5702384B2 (ja) | 2015-04-15 |
Family
ID=43017143
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012522974A Expired - Fee Related JP5702384B2 (ja) | 2009-07-31 | 2010-07-27 | 中空マイクロニードルアレイ |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US10010706B2 (enExample) |
| EP (2) | EP3354312A1 (enExample) |
| JP (1) | JP5702384B2 (enExample) |
| KR (1) | KR101712226B1 (enExample) |
| CN (1) | CN102497909B (enExample) |
| AU (1) | AU2010276511B2 (enExample) |
| BR (1) | BR112012001685B8 (enExample) |
| CA (1) | CA2769102C (enExample) |
| ES (1) | ES2661063T3 (enExample) |
| RU (1) | RU2508135C2 (enExample) |
| WO (1) | WO2011014514A1 (enExample) |
Families Citing this family (154)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0414054D0 (en) | 2004-06-23 | 2004-07-28 | Owen Mumford Ltd | Improvements relating to automatic injection devices |
| US9119945B2 (en) | 2006-04-20 | 2015-09-01 | 3M Innovative Properties Company | Device for applying a microneedle array |
| SG173339A1 (en) | 2006-06-30 | 2011-08-29 | Abbott Biotech Ltd | Automatic injection device |
| EP2664323B1 (en) | 2007-04-16 | 2020-07-29 | Corium, Inc. | Solvent-cast microneedle arrays containing active |
| BRPI0817907B8 (pt) | 2007-10-02 | 2021-06-22 | Lamodel Ltd | aparelho para administrar uma substância a um indivíduo |
| EP3184136B1 (en) | 2010-03-25 | 2021-06-02 | New Injection Systems Ltd | Injector |
| SG184934A1 (en) | 2010-04-21 | 2012-11-29 | Abbott Biotech Ltd | Wearable automatic injection device for controlled delivery of therapeutic agents |
| US9687641B2 (en) | 2010-05-04 | 2017-06-27 | Corium International, Inc. | Method and device for transdermal delivery of parathyroid hormone using a microprojection array |
| AU2015203703B2 (en) * | 2010-05-20 | 2018-01-18 | Becton, Dickinson And Company | Drug delivery device |
| JP5934188B2 (ja) | 2010-05-20 | 2016-06-15 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | 薬物送達装置 |
| GB2483505B (en) * | 2010-09-13 | 2012-10-10 | Ndm Technologies Ltd | Devices for transdermal drug delivery |
| WO2012061556A1 (en) * | 2010-11-03 | 2012-05-10 | Flugen, Inc. | Wearable drug delivery device having spring drive and sliding actuation mechanism |
| KR102202772B1 (ko) | 2011-01-24 | 2021-01-18 | 애브비 바이오테크놀로지 리미티드 | 오버몰딩된 파지면을 갖는 자동 주사 장치 |
| US20140052067A1 (en) * | 2011-03-18 | 2014-02-20 | Universite Libre De Bruxelles | Devices for puncturing for a human or animal body's membrane |
| CN102727992A (zh) * | 2011-03-31 | 2012-10-17 | 株式会社汉比特科技与创新 | 印章式针组件 |
| EP2699286B1 (en) * | 2011-04-21 | 2016-08-31 | AbbVie Inc. | Wearable automatic injection device |
| WO2013006643A1 (en) | 2011-07-06 | 2013-01-10 | The Parkinson's Institute | Compositions and methods for treatment of symptoms in parkinson's disease patients |
| CA2847711C (en) * | 2011-09-07 | 2019-08-20 | 3M Innovative Properties Company | Delivery system for hollow microneedle arrays |
| CA2845384C (en) * | 2011-09-13 | 2020-10-06 | Unitract Syringe Pty Ltd | Sterile fluid pathway connection to drug containers for drug delivery pumps |
| JP6126105B2 (ja) * | 2011-10-12 | 2017-05-10 | スリーエム イノベイティブ プロパティズ カンパニー | 一体化されたマイクロニードル送達システム |
| CN102327656B (zh) * | 2011-10-18 | 2013-05-08 | 清华大学 | 一次性阵列式微型注射针头 |
| KR102143482B1 (ko) | 2011-11-30 | 2020-08-11 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 펩티드 치료제 및 아미노산을 포함하는 마이크로니들 장치, 이의 제조 및 사용 방법 |
| WO2013137831A1 (en) * | 2012-03-16 | 2013-09-19 | National University Of Singapore | A novel method to fabricate polymeric microneedles |
| JP5903016B2 (ja) | 2012-06-27 | 2016-04-13 | コスメディ製薬株式会社 | マイクロニードルパッチの保護離型シート |
| CN104736192B (zh) * | 2012-10-10 | 2018-02-13 | 3M创新有限公司 | 用于将微针装置施用至皮肤的施用装置和方法 |
| WO2014058746A1 (en) | 2012-10-10 | 2014-04-17 | 3M Innovative Properties Company | Force-controlled applicator for applying a microneedle device to skin |
| WO2014062538A1 (en) | 2012-10-19 | 2014-04-24 | 3M Innovative Properties Company | Polysaccharide-containing hydrogels, compositions, articles, and methods |
| USD705422S1 (en) | 2012-10-26 | 2014-05-20 | 3M Innovative Properties Company | Microneedle applicator |
| USD693921S1 (en) | 2012-10-26 | 2013-11-19 | 3M Innovative Properties Company | Microneedle applicator |
| WO2014078545A1 (en) | 2012-11-16 | 2014-05-22 | 3M Innovative Properties Company | Force-controlled applicator for applying a microneedle device to skin |
| EP2922590B1 (en) * | 2012-11-21 | 2020-02-05 | Amgen Inc. | Drug delivery device |
| BR112015011662A2 (pt) | 2012-11-23 | 2017-07-11 | New Injection Systems Ltd | montagem de auto-injetor |
| EP2934660B1 (en) | 2012-12-21 | 2019-07-17 | Corium, Inc. | Microarray for delivery of therapeutic agent and method of making same |
| KR102236575B1 (ko) | 2012-12-21 | 2021-04-05 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 접착제 조립체 및 이를 포함하는 마이크로니들 주사 장치 |
| KR102219636B1 (ko) | 2012-12-27 | 2021-02-23 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 중공형 마이크로니들을 갖는 물품 및 제조 방법 |
| WO2014110016A1 (en) | 2013-01-08 | 2014-07-17 | 3M Innovative Properties Company | Applicator for applying a microneedle device to skin |
| US10105487B2 (en) | 2013-01-24 | 2018-10-23 | Chrono Therapeutics Inc. | Optimized bio-synchronous bioactive agent delivery system |
| KR102571835B1 (ko) * | 2013-02-28 | 2023-08-30 | 소렌토 쎄라퓨틱스, 인코포레이티드 | 경피 약물 전달 장치 |
| WO2014164314A1 (en) | 2013-03-12 | 2014-10-09 | Corium International, Inc. | Microprojection applicators |
| WO2014151654A1 (en) | 2013-03-15 | 2014-09-25 | Corium International, Inc. | Microarray for delivery of therapeutic agent and methods of use |
| EP4194028A1 (en) * | 2013-03-15 | 2023-06-14 | Corium Pharma Solutions, Inc. | Multiple impact microprojection applicators |
| JP2016514133A (ja) | 2013-03-15 | 2016-05-19 | コリウム インターナショナル, インコーポレイテッド | ポリマーを含まない微細構造物を含むマイクロアレイ、製造方法および使用方法 |
| SG11201507885TA (en) | 2013-03-22 | 2015-11-27 | 3M Innovative Properties Co | Microneedle applicator comprising a counter assembly |
| BR112015026199B1 (pt) * | 2013-04-15 | 2022-03-22 | Becton, Dickinson And Company | Dispositivo de coleta de fluido biológico e sistema de separação de fluido biológico |
| SG11201509810TA (en) | 2013-05-31 | 2015-12-30 | 3M Innovative Properties Co | Microneedle injection and infusion apparatus and method of using same |
| EP3003459B1 (en) * | 2013-05-31 | 2018-06-20 | 3M Innovative Properties Company | Microneedle injection apparatus comprising an inverted actuator |
| CN105246541B (zh) * | 2013-05-31 | 2018-01-16 | 3M创新有限公司 | 包括双覆盖件的微针注射设备 |
| WO2015005359A1 (ja) | 2013-07-08 | 2015-01-15 | 凸版印刷株式会社 | 中空針状体装置 |
| US10384047B2 (en) | 2013-07-16 | 2019-08-20 | 3M Innovative Properties Company | Hollow microneedle with bevel opening |
| EP3021930B1 (en) | 2013-07-16 | 2020-10-07 | 3M Innovative Properties Company | Hollow microneedle with beveled tip |
| SG11201600330XA (en) | 2013-07-16 | 2016-02-26 | 3M Innovative Properties Co | Article comprising a microneedle |
| EP3021931B1 (en) | 2013-07-16 | 2021-09-01 | Kindeva Drug Delivery L.P. | Hollow microneedle array article |
| AU2014364930B2 (en) | 2013-12-16 | 2017-06-15 | Massachusetts Institute Of Technology | Micromolded or 3-D printed pulsatile release vaccine formulations |
| EP3082902B1 (en) * | 2013-12-19 | 2019-10-02 | Medtronic MiniMed, Inc. | On-body injector and method of use |
| GB201401133D0 (en) * | 2014-01-23 | 2014-03-12 | Renephra Ltd | Fluid extraction device, applicator device and associated methods |
| US10994112B2 (en) | 2014-02-05 | 2021-05-04 | Amgen Inc. | Drug delivery system with electromagnetic field generator |
| GB201402261D0 (en) * | 2014-02-10 | 2014-03-26 | Owen Mumford Ltd | Injector apparatus |
| ES2939940T3 (es) | 2014-03-28 | 2023-04-28 | Univ Duke | Tratamiento del cáncer de mama utilizando moduladores selectivos de los receptores de estrógenos |
| EP3581236B1 (en) * | 2014-04-30 | 2021-03-03 | Sorrento Therapeutics, Inc. | Transdermal drug delivery apparatus |
| EP3137154B1 (en) * | 2014-04-30 | 2019-09-04 | Sorrento Therapeutics, Inc. | Cartridge portion of transdermal drug delivery apparatus |
| CN106232172B (zh) * | 2014-04-30 | 2020-05-22 | 索伦托治疗有限公司 | 透皮药物递送设备的插座部分和方法 |
| CN104056346B (zh) * | 2014-06-16 | 2017-04-26 | 游学秋 | 异平面微针阵列及其制作方法 |
| JPWO2016006409A1 (ja) | 2014-07-09 | 2017-04-27 | 凸版印刷株式会社 | 液剤注入装置 |
| CN104117138A (zh) * | 2014-07-24 | 2014-10-29 | 河南科技大学 | 一种超声微针复合经皮给药装置 |
| US10624843B2 (en) | 2014-09-04 | 2020-04-21 | Corium, Inc. | Microstructure array, methods of making, and methods of use |
| WO2016072060A1 (ja) | 2014-11-05 | 2016-05-12 | 凸版印刷株式会社 | マイクロニードルセット |
| US10010708B2 (en) * | 2014-12-20 | 2018-07-03 | Esthetic Education LLC | Microneedle cartridge and nosecone assembly |
| EP3037124A1 (en) | 2014-12-22 | 2016-06-29 | Universite Libre De Bruxelles | Drug delivery device with microneedles |
| KR102498515B1 (ko) | 2015-01-21 | 2023-02-09 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 마이크로니들 어레이 및 사용 방법 |
| SG11201706081SA (en) | 2015-01-27 | 2017-08-30 | 3M Innovative Properties Co | Alum-containing coating formulations for microneedle vaccine patches |
| JP2018511355A (ja) | 2015-01-28 | 2018-04-26 | クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. | 薬剤送達方法及びシステム |
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