JP5698421B2 - 細胞の無菌増殖のための装置 - Google Patents

細胞の無菌増殖のための装置 Download PDF

Info

Publication number
JP5698421B2
JP5698421B2 JP2014536331A JP2014536331A JP5698421B2 JP 5698421 B2 JP5698421 B2 JP 5698421B2 JP 2014536331 A JP2014536331 A JP 2014536331A JP 2014536331 A JP2014536331 A JP 2014536331A JP 5698421 B2 JP5698421 B2 JP 5698421B2
Authority
JP
Japan
Prior art keywords
container
cells
vent
port
lid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2014536331A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014530618A5 (enExample
JP2014530618A (ja
Inventor
ライナー・ルートヴィヒ・クナウス
ギャヴィン・ホームズ
ケーティ・レベッカ・ニュートン
ティナ・レスリー・クロンビー
アンドリュー・ロイ・マクラウド・プロヴァン
Original Assignee
セル・メディカ・リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by セル・メディカ・リミテッド filed Critical セル・メディカ・リミテッド
Publication of JP2014530618A publication Critical patent/JP2014530618A/ja
Publication of JP2014530618A5 publication Critical patent/JP2014530618A5/ja
Application granted granted Critical
Publication of JP5698421B2 publication Critical patent/JP5698421B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/08Flask, bottle or test tube
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/24Gas permeable parts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02Membranes; Filters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/20Degassing; Venting; Bubble traps
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • C12M37/02Filters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • C12M37/04Seals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0636T lymphocytes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Immunology (AREA)
  • Clinical Laboratory Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2014536331A 2011-10-21 2012-10-19 細胞の無菌増殖のための装置 Expired - Fee Related JP5698421B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161550246P 2011-10-21 2011-10-21
US61/550,246 2011-10-21
PCT/GB2012/052587 WO2013057500A1 (en) 2011-10-21 2012-10-19 Device for the aseptic expansion of cells

Publications (3)

Publication Number Publication Date
JP2014530618A JP2014530618A (ja) 2014-11-20
JP2014530618A5 JP2014530618A5 (enExample) 2015-02-05
JP5698421B2 true JP5698421B2 (ja) 2015-04-08

Family

ID=47116088

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014536331A Expired - Fee Related JP5698421B2 (ja) 2011-10-21 2012-10-19 細胞の無菌増殖のための装置

Country Status (10)

Country Link
US (3) US9315774B2 (enExample)
EP (1) EP2768939B1 (enExample)
JP (1) JP5698421B2 (enExample)
KR (1) KR101499929B1 (enExample)
AU (1) AU2012324644B2 (enExample)
DK (1) DK2768939T3 (enExample)
ES (1) ES2598055T3 (enExample)
HU (1) HUE031348T2 (enExample)
PL (1) PL2768939T3 (enExample)
WO (1) WO2013057500A1 (enExample)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013057500A1 (en) * 2011-10-21 2013-04-25 Cell Medica Limited Device for the aseptic expansion of cells
CN102517210B (zh) * 2011-12-08 2014-05-14 湖北民族学院 一种全波长可控光源的生物反应装置
SG10201705494YA (en) 2013-06-24 2017-08-30 Wolf Wilson Mfg Corp Closed system device and methods for gas permeable cell culture process
EP3059301A4 (en) * 2013-10-16 2017-08-30 Medican Inc. Apparatus and method for continuous cell culture
US20170044496A1 (en) 2014-04-10 2017-02-16 H. Lee Moffitt Cancer Center And Research Institute, Inc. Enhanced Expansion of Tumor-Infiltrating Lymphocytes for Adoptive Cell Therapy
MX2019000149A (es) 2016-07-07 2019-09-23 Iovance Biotherapeutics Inc Proteinas de union a ligando 1 de muerte programada 1 (pd-l1) y metodos de uso de las mismas.
US20210292696A1 (en) * 2016-09-22 2021-09-23 Corning Incorporated Gravity flow cell culture devices, systems, and methods of use thereof
PL3532607T3 (pl) 2016-10-26 2024-07-01 Iovance Biotherapeutics, Inc. Restymulacja kriokonserwowanych limfocytów naciekających guza nowotworowego
TWI788307B (zh) 2016-10-31 2023-01-01 美商艾歐凡斯生物治療公司 用於擴增腫瘤浸潤性淋巴細胞之工程化人造抗原呈現細胞
TWI826360B (zh) 2016-11-17 2023-12-21 美商艾歐凡斯生物治療公司 殘餘腫瘤浸潤性淋巴細胞及製備和使用彼之方法
JP7664020B2 (ja) 2017-01-06 2025-04-17 アイオバンス バイオセラピューティクス,インコーポレイテッド カリウムチャネルアゴニストによる腫瘍浸潤リンパ球の増殖及びその治療的使用
US11254913B1 (en) 2017-03-29 2022-02-22 Iovance Biotherapeutics, Inc. Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
JOP20190224A1 (ar) * 2017-03-29 2019-09-26 Iovance Biotherapeutics Inc عمليات من أجل إنتاج الخلايا اللمفاوية المرتشحة للأورام واستخداماتها في العلاج المناعي
USD846733S1 (en) * 2017-04-04 2019-04-23 Arc Medical Design Limited Specimen trap
USD846732S1 (en) * 2017-04-04 2019-04-23 Arc Medical Design Limited Specimen trap
USD820085S1 (en) 2017-05-19 2018-06-12 Pura Stainless Llc Fluid container spout with straw
CN110662762A (zh) 2017-05-24 2020-01-07 诺华股份有限公司 抗体细胞因子移植蛋白和用于治疗癌症的方法
AR112072A1 (es) * 2017-06-05 2019-09-18 Iovance Biotherapeutics Inc Métodos de uso de linfocitos infiltrantes de tumor en melanoma doble refractario
USD848023S1 (en) * 2017-11-09 2019-05-07 3088081 Canada Inc. Sample vial
US11713446B2 (en) 2018-01-08 2023-08-01 Iovance Biotherapeutics, Inc. Processes for generating TIL products enriched for tumor antigen-specific T-cells
KR102956273B1 (ko) 2018-01-08 2026-04-24 이오반스 바이오테라퓨틱스, 인크. 종양 항원-특이적 t-세포에 대해 풍부화된 til 생성물의 생성 방법
US10889792B2 (en) 2018-02-09 2021-01-12 Global Life Sciences Solutions Usa Llc Cell expansion vessel systems and methods
DE102018103634B3 (de) * 2018-02-19 2019-07-04 Sartorius Stedim Biotech Gmbh Medienfiltrationsvorrichtung und Verfahren zur Medienfiltration
USD842105S1 (en) * 2018-02-20 2019-03-05 Paw Bioscience Products, Llc Connector cap for tubes
EP3784254A1 (en) 2018-04-27 2021-03-03 Iovance Biotherapeutics, Inc. Closed process for expansion and gene editing of tumor infiltrating lymphocytes and uses of same in immunotherapy
WO2019217753A1 (en) * 2018-05-10 2019-11-14 Iovance Biotherapeutics, Inc. Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
USD912247S1 (en) * 2018-05-17 2021-03-02 Dwk Life Sciences Gmbh Connection cap device
TW202039831A (zh) 2018-11-05 2020-11-01 美商艾歐凡斯生物治療公司 對抗pd-1抗體呈現難治性之非小細胞肺癌(nsclc)病患之治療
CR20210295A (es) 2018-11-05 2021-07-09 Iovance Biotherapeutics Inc Procesos para la producción de linfocitos infiltrantes de tumor y usos de estos en inmunoterapia
WO2020141327A1 (en) 2019-01-04 2020-07-09 Oribiotech Ltd Cell processing device cell processing system and methods of use thereof
CN113423811B (zh) * 2019-03-25 2024-04-05 泰尔茂株式会社 用于在洁净度高的空间中制备细胞培养物的容器及套件
JP7352146B2 (ja) * 2019-07-23 2023-09-28 住友ベークライト株式会社 分離器及び培養システム
USD895421S1 (en) * 2019-10-31 2020-09-08 Rodney Laible Dual straw container insert
USD899925S1 (en) * 2019-10-31 2020-10-27 Rodney Laible Dual draw cap adapter
WO2021118990A1 (en) 2019-12-11 2021-06-17 Iovance Biotherapeutics, Inc. Processes for the production of tumor infiltrating lymphocytes (tils) and methods of using the same
USD932048S1 (en) * 2020-04-07 2021-09-28 Rodney Laible Four port cap adapter
JP2023524639A (ja) 2020-04-22 2023-06-13 アイオバンス バイオセラピューティクス,インコーポレイテッド 患者特異的免疫療法用細胞の製造調整システム及び調整方法
US12365871B2 (en) 2020-04-28 2025-07-22 Lyell Immunopharma, Inc. Methods for culturing cells
USD964553S1 (en) 2020-05-29 2022-09-20 Keymed (Medical & Industrial Equipment) Limited Medical instrument
US12612586B2 (en) * 2020-08-26 2026-04-28 Shimadzu Corporation Cell culture container and cell culture system
EP4225330A1 (en) 2020-10-06 2023-08-16 Iovance Biotherapeutics, Inc. Treatment of nsclc patients with tumor infiltrating lymphocyte therapies
US20220112467A1 (en) * 2020-10-09 2022-04-14 Vbc Holdings Llc Closed-system method and kit of disposable assemblies for isolating mesenchymal stromal cells from lipoaspirate
WO2022204564A2 (en) 2021-03-25 2022-09-29 Iovance Biotherapeutics, Inc. Methods and compositions for t-cell coculture potency assays and use with cell therapy products
US11718819B2 (en) 2021-09-22 2023-08-08 Shanghai Longevity Co., Ltd. Cell proliferation bioreactor
WO2023201369A1 (en) * 2022-04-15 2023-10-19 Iovance Biotherapeutics, Inc. Til expansion processes using specific cytokine combinations and/or akti treatment
US20260092248A1 (en) * 2022-09-15 2026-04-02 Life Technologies Corporation Bioreactors operable in static and dynamic modes and methods of use
EP4704933A1 (en) 2023-05-03 2026-03-11 Volumina Medical SA Devices and methods for preparing and conditioning biological assemblies for minimally invasive delivery for tissue engineering, cell therapies and other therapeutic applications
USD1103765S1 (en) * 2023-08-09 2025-12-02 Molecular Devices (Austria) GmbH Interface flange for a bottle

Family Cites Families (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3855997A (en) * 1973-07-11 1974-12-24 Cinco Medical Health Supply Co Sterile specimen trap
US4184916A (en) * 1977-11-14 1980-01-22 Monsanto Company Continuous cell culture system
US4166768A (en) * 1977-11-14 1979-09-04 Monsanto Company Continuous cell culture system
US4178209A (en) * 1977-11-14 1979-12-11 Monsanto Company Continuous cell culture method and apparatus
USD282283S (en) * 1982-04-23 1986-01-21 James Weigl Sensor line fitting for a respiratory system
US4661455A (en) * 1986-01-16 1987-04-28 Dorr-Oliver Incorporated Membrane cell culturing device
JPS62195276A (ja) * 1986-02-20 1987-08-28 Kyowa Hakko Kogyo Co Ltd 細胞培養法
USD306266S (en) * 1986-06-13 1990-02-27 Hargrove Barry C Sampling bottle closure
USD303428S (en) * 1986-08-20 1989-09-12 Terumo Kabushiki Kaisha Culture dish
US4839292B1 (en) * 1987-09-11 1994-09-13 Joseph G Cremonese Cell culture flask utilizing membrane barrier
US4810246A (en) * 1987-11-04 1989-03-07 L. Vad Technology, Inc. Disposable cell culture chamber with remote access
USD316753S (en) * 1988-08-19 1991-05-07 Troy Biologicals, Inc. Culture dish
USD322323S (en) * 1989-01-03 1991-12-10 Serono Diagnostics Partners Container for use in immunoassay
USD370411S (en) * 1990-02-08 1996-06-04 Vernon Iv Carlton H Combined jar and plunger
USD336043S (en) * 1991-03-27 1993-06-01 Provencio David A Beverage container cover
JPH05123182A (ja) * 1991-10-30 1993-05-21 Nakano Vinegar Co Ltd 静置培養による微生物セルロースの製造法及びその装置
US5350080A (en) * 1993-02-10 1994-09-27 Hyclone Laboratories Multi-access port for use in a cell culture media system
JP3244847B2 (ja) * 1993-03-16 2002-01-07 宇宙開発事業団 細胞培養容器
USD359684S (en) * 1994-03-17 1995-06-27 Abbott Laboratories Container closure with tubing extending therefrom
US5693537A (en) * 1994-06-28 1997-12-02 Wilson; John R. Compartmentalized tissue culture flask
ATE292673T1 (de) * 1994-06-28 2005-04-15 Wilson Wolf Corp Zellkulturflasche mit mehreren kammern
US5728581A (en) 1995-06-07 1998-03-17 Systemix, Inc. Method of expanding hematopoietic stem cells, reagents and bioreactors for use therein
DE19529099C2 (de) * 1995-08-08 1997-12-04 Forschungszentrum Juelich Gmbh Vorrichtung zur Serien-Kultivierung von Mikroorganismen bzw. Zellen in begasten Flüssigkeitssäulen
USD404497S (en) * 1995-09-27 1999-01-19 Becton Dickinson And Company Cell insert assembly
US5624418A (en) * 1995-10-04 1997-04-29 Shepard; R. David Collection and separation device
US6027694A (en) * 1996-10-17 2000-02-22 Texperts, Inc. Spillproof microplate assembly
US6500390B1 (en) * 1996-10-17 2002-12-31 David A. Boulton Method for sealing and venting a microplate assembly
USD399097S (en) * 1997-03-31 1998-10-06 Heng-Te Yang Container
USD399098S (en) * 1997-03-31 1998-10-06 Heng-Te Yang Container
USD425624S (en) * 1999-02-18 2000-05-23 Edu-Science (H.K.) Ltd. Petri dish
USD459656S1 (en) * 2001-01-19 2002-07-02 Polo Ralph Lauren Corporation Bottle
JP2003125753A (ja) * 2001-10-26 2003-05-07 Hideo Tanaka フラスコ用栓
USD489008S1 (en) * 2002-08-05 2004-04-27 Euroitalia S.R.L. Container for perfumes and cosmetic products
CN101120083B (zh) * 2003-10-08 2013-03-27 威尔森沃尔夫制造公司 利用透气性材料进行细胞培养的方法及装置
KR101139090B1 (ko) * 2003-12-18 2012-04-30 가부시키가이샤 가네카 세포 배양 장치
US20080032396A1 (en) * 2006-08-02 2008-02-07 Becton, Dickinson And Company Bioreactor and Method
JP5098471B2 (ja) * 2007-07-06 2012-12-12 株式会社フコク 細胞培養用トレイ状容器並びに同容器への収容物の充填方法
KR100932861B1 (ko) * 2007-11-30 2009-12-21 코아스템(주) 세포배양플라스크
USD638136S1 (en) * 2010-01-06 2011-05-17 Origio, Inc. Embryo or cell culture apparatus
WO2011146046A1 (en) * 2010-05-17 2011-11-24 Yale University System for seeding cells onto three dimensional scaffolds
US9220485B2 (en) * 2010-08-28 2015-12-29 Endochoice, Inc. Tissue collection and separation device
US8465439B2 (en) * 2010-08-28 2013-06-18 Endochoice, Inc. Tissue collection and separation device
USD637733S1 (en) * 2010-09-14 2011-05-10 SPI, Inc. Conical embryo culture plate
USD667959S1 (en) * 2011-01-25 2012-09-25 Steve Lin Multiple configuration cap
USD678544S1 (en) * 2011-08-02 2013-03-19 Sartorius Weighing Technology Gmbh Cell culturing vessel
WO2013057500A1 (en) * 2011-10-21 2013-04-25 Cell Medica Limited Device for the aseptic expansion of cells
USD674505S1 (en) * 2012-03-12 2013-01-15 Genx International, Inc. Specimen culturing dish
US8945383B2 (en) * 2012-03-16 2015-02-03 Kx Technologies Llc Filtration system
USD690826S1 (en) * 2012-04-12 2013-10-01 Becton Dickinson And Company Vessel assembly
USD700354S1 (en) * 2012-06-04 2014-02-25 Unisense Fertilitech A/S Embryo slide culture dish
USD744857S1 (en) * 2013-03-15 2015-12-08 Mccormick & Company, Incorporated Bottle with cap
USD698940S1 (en) * 2013-04-25 2014-02-04 Vitrolife Kft Culture dish
USD728123S1 (en) * 2013-07-12 2015-04-28 D. Roy Cullimore Storage device for microorganisms
USD771832S1 (en) * 2014-06-17 2016-11-15 Medline Industries, Inc. Lid and screen assembly of a sample collection container with screen
USD767162S1 (en) * 2015-11-03 2016-09-20 Timothy Schimmel Culture dish
USD767160S1 (en) * 2015-11-03 2016-09-20 Timothy Schimmel Culture dish
USD767161S1 (en) * 2015-11-03 2016-09-20 Timothy Schimmel Culture dish

Also Published As

Publication number Publication date
AU2012324644A1 (en) 2014-05-22
EP2768939B1 (en) 2016-08-17
USD820996S1 (en) 2018-06-19
EP2768939A1 (en) 2014-08-27
HUE031348T2 (hu) 2017-07-28
WO2013057500A1 (en) 2013-04-25
KR101499929B1 (ko) 2015-03-06
ES2598055T3 (es) 2017-01-25
US9315774B2 (en) 2016-04-19
US20160201021A1 (en) 2016-07-14
US20140273077A1 (en) 2014-09-18
HK1201289A1 (zh) 2015-08-28
PL2768939T3 (pl) 2017-02-28
DK2768939T3 (en) 2016-11-07
KR20140097174A (ko) 2014-08-06
US10221391B2 (en) 2019-03-05
JP2014530618A (ja) 2014-11-20
AU2012324644B2 (en) 2014-08-28

Similar Documents

Publication Publication Date Title
JP2014530618A (ja) 細胞の無菌増殖のための装置
US11525111B2 (en) Bag assembly for cultivation of cells
CN109124746B (zh) Ivf卵收集室
US20100209966A1 (en) Aseptic bioreactor system for processing biological materials
US20230023994A1 (en) Methods for separating suspensions using single-use centrifuge containers
US20210222103A1 (en) Structured bag for cell culture
JP2014530618A5 (enExample)
CN102046772A (zh) 具有漩涡破坏器的容器和系统
CN218290897U (zh) 细胞培养系统
CA3099573C (en) Method and system for recovering fluid
KR20210084301A (ko) 유체를 회수하기 위한 방법 및 시스템
US20240351042A1 (en) Outlet valve for a container
HK1201289B (en) Device for the aseptic expansion of cells
CN202036527U (zh) 气压式输液袋
JP2019180365A (ja) 遠心バッグと一体になった動物細胞培養用バッグ
CN208636088U (zh) 一种无菌取样装置
JPH03187375A (ja) 培養液の取出し方法および固形分除去方法

Legal Events

Date Code Title Description
A975 Report on accelerated examination

Free format text: JAPANESE INTERMEDIATE CODE: A971005

Effective date: 20140925

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20141006

A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20141211

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20150113

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20150212

R150 Certificate of patent or registration of utility model

Ref document number: 5698421

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees