JP2014530618A5 - - Google Patents
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- Publication number
- JP2014530618A5 JP2014530618A5 JP2014536331A JP2014536331A JP2014530618A5 JP 2014530618 A5 JP2014530618 A5 JP 2014530618A5 JP 2014536331 A JP2014536331 A JP 2014536331A JP 2014536331 A JP2014536331 A JP 2014536331A JP 2014530618 A5 JP2014530618 A5 JP 2014530618A5
- Authority
- JP
- Japan
- Prior art keywords
- container
- cells
- port
- culture
- vent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007788 liquid Substances 0.000 claims description 4
- 210000004027 cell Anatomy 0.000 claims 17
- 238000000034 method Methods 0.000 claims 7
- 239000012530 fluid Substances 0.000 claims 4
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims 3
- 238000012258 culturing Methods 0.000 claims 3
- 230000001225 therapeutic effect Effects 0.000 claims 3
- 238000003306 harvesting Methods 0.000 claims 2
- 210000001744 T-lymphocyte Anatomy 0.000 claims 1
- 238000004113 cell culture Methods 0.000 claims 1
- 230000010261 cell growth Effects 0.000 claims 1
- 230000005484 gravity Effects 0.000 claims 1
- 235000015097 nutrients Nutrition 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 238000011287 therapeutic dose Methods 0.000 claims 1
- 238000005406 washing Methods 0.000 claims 1
- 238000011084 recovery Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161550246P | 2011-10-21 | 2011-10-21 | |
| US61/550,246 | 2011-10-21 | ||
| PCT/GB2012/052587 WO2013057500A1 (en) | 2011-10-21 | 2012-10-19 | Device for the aseptic expansion of cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014530618A JP2014530618A (ja) | 2014-11-20 |
| JP2014530618A5 true JP2014530618A5 (enExample) | 2015-02-05 |
| JP5698421B2 JP5698421B2 (ja) | 2015-04-08 |
Family
ID=47116088
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014536331A Expired - Fee Related JP5698421B2 (ja) | 2011-10-21 | 2012-10-19 | 細胞の無菌増殖のための装置 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US9315774B2 (enExample) |
| EP (1) | EP2768939B1 (enExample) |
| JP (1) | JP5698421B2 (enExample) |
| KR (1) | KR101499929B1 (enExample) |
| AU (1) | AU2012324644B2 (enExample) |
| DK (1) | DK2768939T3 (enExample) |
| ES (1) | ES2598055T3 (enExample) |
| HU (1) | HUE031348T2 (enExample) |
| PL (1) | PL2768939T3 (enExample) |
| WO (1) | WO2013057500A1 (enExample) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2768939T3 (en) * | 2011-10-21 | 2016-11-07 | Cell Medica Ltd | Device for aseptic expansion of cells |
| CN102517210B (zh) * | 2011-12-08 | 2014-05-14 | 湖北民族学院 | 一种全波长可控光源的生物反应装置 |
| AU2014302589B2 (en) | 2013-06-24 | 2020-05-14 | Wilson Wolf Manufacturing, LLC | Closed system device and methods for gas permeable cell culture process |
| EP3059301A4 (en) * | 2013-10-16 | 2017-08-30 | Medican Inc. | Apparatus and method for continuous cell culture |
| US20170044496A1 (en) | 2014-04-10 | 2017-02-16 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Enhanced Expansion of Tumor-Infiltrating Lymphocytes for Adoptive Cell Therapy |
| SG11201900138TA (en) | 2016-07-07 | 2019-02-27 | Iovance Biotherapeutics Inc | Programmed death 1 ligand 1 (pd-l1) binding proteins and methods of use thereof |
| US20210292696A1 (en) * | 2016-09-22 | 2021-09-23 | Corning Incorporated | Gravity flow cell culture devices, systems, and methods of use thereof |
| AU2017347851B2 (en) | 2016-10-26 | 2024-03-07 | Iovance Biotherapeutics, Inc. | Restimulation of cryopreserved tumor infiltrating lymphocytes |
| TWI788307B (zh) | 2016-10-31 | 2023-01-01 | 美商艾歐凡斯生物治療公司 | 用於擴增腫瘤浸潤性淋巴細胞之工程化人造抗原呈現細胞 |
| WO2018094167A1 (en) | 2016-11-17 | 2018-05-24 | Iovance Biotherapeutics, Inc. | Remnant tumor infiltrating lymphocytes and methods of preparing and using the same |
| CA3049165A1 (en) | 2017-01-06 | 2018-07-12 | Iovance Biotherapeutics, Inc. | Expansion of tumor infiltrating lymphocytes with potassium channel agonists and therapeutic uses thereof |
| JOP20190224A1 (ar) | 2017-03-29 | 2019-09-26 | Iovance Biotherapeutics Inc | عمليات من أجل إنتاج الخلايا اللمفاوية المرتشحة للأورام واستخداماتها في العلاج المناعي |
| US11254913B1 (en) | 2017-03-29 | 2022-02-22 | Iovance Biotherapeutics, Inc. | Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy |
| USD846733S1 (en) * | 2017-04-04 | 2019-04-23 | Arc Medical Design Limited | Specimen trap |
| USD846732S1 (en) * | 2017-04-04 | 2019-04-23 | Arc Medical Design Limited | Specimen trap |
| USD820085S1 (en) | 2017-05-19 | 2018-06-12 | Pura Stainless Llc | Fluid container spout with straw |
| IL322309A (en) | 2017-05-24 | 2025-09-01 | Novartis Ag | IL2 antibody grafted proteins and methods of use in cancer treatment |
| US11819517B2 (en) * | 2017-06-05 | 2023-11-21 | Iovance Biotherapeutics, Inc. | Methods of using tumor infiltrating lymphocytes in double-refractory melanoma |
| USD848023S1 (en) * | 2017-11-09 | 2019-05-07 | 3088081 Canada Inc. | Sample vial |
| JP2021509586A (ja) | 2018-01-08 | 2021-04-01 | アイオバンス バイオセラピューティクス,インコーポレイテッド | 腫瘍抗原特異的t細胞について濃縮されたtil製品を生成するためのプロセス |
| US11713446B2 (en) | 2018-01-08 | 2023-08-01 | Iovance Biotherapeutics, Inc. | Processes for generating TIL products enriched for tumor antigen-specific T-cells |
| US10889792B2 (en) | 2018-02-09 | 2021-01-12 | Global Life Sciences Solutions Usa Llc | Cell expansion vessel systems and methods |
| DE102018103634B3 (de) * | 2018-02-19 | 2019-07-04 | Sartorius Stedim Biotech Gmbh | Medienfiltrationsvorrichtung und Verfahren zur Medienfiltration |
| USD842105S1 (en) * | 2018-02-20 | 2019-03-05 | Paw Bioscience Products, Llc | Connector cap for tubes |
| TWI831776B (zh) | 2018-04-27 | 2024-02-11 | 美商艾歐凡斯生物治療公司 | 腫瘤浸潤性淋巴細胞之基因編輯和彼於免疫治療之用途 |
| US12473532B2 (en) | 2018-05-10 | 2025-11-18 | Iovance Biotherapeutics, Inc. | Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy |
| USD912247S1 (en) * | 2018-05-17 | 2021-03-02 | Dwk Life Sciences Gmbh | Connection cap device |
| WO2020096988A2 (en) | 2018-11-05 | 2020-05-14 | Iovance Biotherapeutics, Inc. | Processes for production of tumor infiltrating lymphocytes and uses of the same in immunotherapy |
| AU2020205031B2 (en) | 2019-01-04 | 2025-10-02 | Oribiotech Ltd | Cell processing unit, cell processing system and methods of use thereof |
| CN113423811B (zh) * | 2019-03-25 | 2024-04-05 | 泰尔茂株式会社 | 用于在洁净度高的空间中制备细胞培养物的容器及套件 |
| JP7352146B2 (ja) * | 2019-07-23 | 2023-09-28 | 住友ベークライト株式会社 | 分離器及び培養システム |
| USD895421S1 (en) * | 2019-10-31 | 2020-09-08 | Rodney Laible | Dual straw container insert |
| USD899925S1 (en) * | 2019-10-31 | 2020-10-27 | Rodney Laible | Dual draw cap adapter |
| USD932048S1 (en) * | 2020-04-07 | 2021-09-28 | Rodney Laible | Four port cap adapter |
| IL297442A (en) | 2020-04-22 | 2022-12-01 | Iovance Biotherapeutics Inc | Systems and methods for coordinating production of cells for patient-specific immunotherapy |
| CN115768879A (zh) | 2020-04-28 | 2023-03-07 | 莱尔免疫制药公司 | 用于培养细胞的方法 |
| USD964553S1 (en) | 2020-05-29 | 2022-09-20 | Keymed (Medical & Industrial Equipment) Limited | Medical instrument |
| EP4206311A4 (en) * | 2020-08-26 | 2025-08-20 | Shimadzu Corp | CELL CULTURE VESSEL AND CELL CULTURE SYSTEM |
| EP4225897A1 (en) * | 2020-10-09 | 2023-08-16 | VBC Holdings LLC | Closed-system method and kit of disposable assemblies for isolating mesenchymal stromal cells from lipoaspirate |
| US11718819B2 (en) | 2021-09-22 | 2023-08-08 | Shanghai Longevity Co., Ltd. | Cell proliferation bioreactor |
| CA3248034A1 (en) | 2022-04-15 | 2023-10-19 | Iovance Biotherapeutics Inc | METHODS FOR EXPANSION OF TIL CELLS BY MEANS OF SPECIFIC CYTOKINE COMBINATIONS AND/OR AKT INHIBITOR TREATMENT |
| EP4587549A2 (en) * | 2022-09-15 | 2025-07-23 | Life Technologies Corporation | Bioreactors operable in static and dynamic modes and methods of use |
| WO2024227265A1 (en) * | 2023-05-03 | 2024-11-07 | Volumina Medical Sa | Devices and methods for preparing and conditioning biological assemblies for minimally invasive delivery for tissue engineering, cell therapies and other therapeutic applications |
| USD1103765S1 (en) * | 2023-08-09 | 2025-12-02 | Molecular Devices (Austria) GmbH | Interface flange for a bottle |
Family Cites Families (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3855997A (en) * | 1973-07-11 | 1974-12-24 | Cinco Medical Health Supply Co | Sterile specimen trap |
| US4166768A (en) * | 1977-11-14 | 1979-09-04 | Monsanto Company | Continuous cell culture system |
| US4184916A (en) * | 1977-11-14 | 1980-01-22 | Monsanto Company | Continuous cell culture system |
| US4178209A (en) * | 1977-11-14 | 1979-12-11 | Monsanto Company | Continuous cell culture method and apparatus |
| USD282283S (en) * | 1982-04-23 | 1986-01-21 | James Weigl | Sensor line fitting for a respiratory system |
| US4661455A (en) * | 1986-01-16 | 1987-04-28 | Dorr-Oliver Incorporated | Membrane cell culturing device |
| JPS62195276A (ja) * | 1986-02-20 | 1987-08-28 | Kyowa Hakko Kogyo Co Ltd | 細胞培養法 |
| USD306266S (en) * | 1986-06-13 | 1990-02-27 | Hargrove Barry C | Sampling bottle closure |
| USD303428S (en) * | 1986-08-20 | 1989-09-12 | Terumo Kabushiki Kaisha | Culture dish |
| US4839292B1 (en) | 1987-09-11 | 1994-09-13 | Joseph G Cremonese | Cell culture flask utilizing membrane barrier |
| US4810246A (en) * | 1987-11-04 | 1989-03-07 | L. Vad Technology, Inc. | Disposable cell culture chamber with remote access |
| USD316753S (en) * | 1988-08-19 | 1991-05-07 | Troy Biologicals, Inc. | Culture dish |
| USD322323S (en) * | 1989-01-03 | 1991-12-10 | Serono Diagnostics Partners | Container for use in immunoassay |
| USD370411S (en) * | 1990-02-08 | 1996-06-04 | Vernon Iv Carlton H | Combined jar and plunger |
| USD336043S (en) * | 1991-03-27 | 1993-06-01 | Provencio David A | Beverage container cover |
| JPH05123182A (ja) * | 1991-10-30 | 1993-05-21 | Nakano Vinegar Co Ltd | 静置培養による微生物セルロースの製造法及びその装置 |
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| JP3244847B2 (ja) * | 1993-03-16 | 2002-01-07 | 宇宙開発事業団 | 細胞培養容器 |
| USD359684S (en) * | 1994-03-17 | 1995-06-27 | Abbott Laboratories | Container closure with tubing extending therefrom |
| US5693537A (en) * | 1994-06-28 | 1997-12-02 | Wilson; John R. | Compartmentalized tissue culture flask |
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| USD404497S (en) * | 1995-09-27 | 1999-01-19 | Becton Dickinson And Company | Cell insert assembly |
| US5624418A (en) * | 1995-10-04 | 1997-04-29 | Shepard; R. David | Collection and separation device |
| US6500390B1 (en) * | 1996-10-17 | 2002-12-31 | David A. Boulton | Method for sealing and venting a microplate assembly |
| US6027694A (en) * | 1996-10-17 | 2000-02-22 | Texperts, Inc. | Spillproof microplate assembly |
| USD399097S (en) * | 1997-03-31 | 1998-10-06 | Heng-Te Yang | Container |
| USD399098S (en) * | 1997-03-31 | 1998-10-06 | Heng-Te Yang | Container |
| USD425624S (en) * | 1999-02-18 | 2000-05-23 | Edu-Science (H.K.) Ltd. | Petri dish |
| USD459656S1 (en) * | 2001-01-19 | 2002-07-02 | Polo Ralph Lauren Corporation | Bottle |
| JP2003125753A (ja) * | 2001-10-26 | 2003-05-07 | Hideo Tanaka | フラスコ用栓 |
| USD490323S1 (en) * | 2002-08-05 | 2004-05-25 | Euroitalia S.R.L. | Container for perfumes and cosmetic products |
| CN103173354B (zh) * | 2003-10-08 | 2017-07-14 | 威尔森沃尔夫制造公司 | 利用透气性材料进行细胞培养的方法及装置 |
| JPWO2005059091A1 (ja) * | 2003-12-18 | 2007-12-13 | 株式会社日立メディコ | 細胞培養装置 |
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| JP5098471B2 (ja) * | 2007-07-06 | 2012-12-12 | 株式会社フコク | 細胞培養用トレイ状容器並びに同容器への収容物の充填方法 |
| KR100932861B1 (ko) * | 2007-11-30 | 2009-12-21 | 코아스템(주) | 세포배양플라스크 |
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| AU2010353739B2 (en) * | 2010-05-17 | 2014-03-27 | Pall Corporation | System for seeding cells onto three dimensional scaffolds |
| US9220485B2 (en) * | 2010-08-28 | 2015-12-29 | Endochoice, Inc. | Tissue collection and separation device |
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| USD637733S1 (en) * | 2010-09-14 | 2011-05-10 | SPI, Inc. | Conical embryo culture plate |
| USD667959S1 (en) * | 2011-01-25 | 2012-09-25 | Steve Lin | Multiple configuration cap |
| USD678544S1 (en) * | 2011-08-02 | 2013-03-19 | Sartorius Weighing Technology Gmbh | Cell culturing vessel |
| DK2768939T3 (en) * | 2011-10-21 | 2016-11-07 | Cell Medica Ltd | Device for aseptic expansion of cells |
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| US8945383B2 (en) * | 2012-03-16 | 2015-02-03 | Kx Technologies Llc | Filtration system |
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| USD700354S1 (en) * | 2012-06-04 | 2014-02-25 | Unisense Fertilitech A/S | Embryo slide culture dish |
| USD744857S1 (en) * | 2013-03-15 | 2015-12-08 | Mccormick & Company, Incorporated | Bottle with cap |
| USD698940S1 (en) * | 2013-04-25 | 2014-02-04 | Vitrolife Kft | Culture dish |
| USD728123S1 (en) * | 2013-07-12 | 2015-04-28 | D. Roy Cullimore | Storage device for microorganisms |
| USD771832S1 (en) * | 2014-06-17 | 2016-11-15 | Medline Industries, Inc. | Lid and screen assembly of a sample collection container with screen |
| USD767162S1 (en) * | 2015-11-03 | 2016-09-20 | Timothy Schimmel | Culture dish |
| USD767161S1 (en) * | 2015-11-03 | 2016-09-20 | Timothy Schimmel | Culture dish |
| USD767160S1 (en) * | 2015-11-03 | 2016-09-20 | Timothy Schimmel | Culture dish |
-
2012
- 2012-10-19 DK DK12780267.6T patent/DK2768939T3/en active
- 2012-10-19 WO PCT/GB2012/052587 patent/WO2013057500A1/en not_active Ceased
- 2012-10-19 ES ES12780267.6T patent/ES2598055T3/es active Active
- 2012-10-19 EP EP12780267.6A patent/EP2768939B1/en not_active Not-in-force
- 2012-10-19 PL PL12780267T patent/PL2768939T3/pl unknown
- 2012-10-19 KR KR1020147013014A patent/KR101499929B1/ko not_active Expired - Fee Related
- 2012-10-19 AU AU2012324644A patent/AU2012324644B2/en not_active Ceased
- 2012-10-19 US US14/353,170 patent/US9315774B2/en not_active Expired - Fee Related
- 2012-10-19 HU HUE12780267A patent/HUE031348T2/hu unknown
- 2012-10-19 JP JP2014536331A patent/JP5698421B2/ja not_active Expired - Fee Related
-
2014
- 2014-03-14 US US29/485,083 patent/USD820996S1/en active Active
-
2016
- 2016-03-18 US US15/075,048 patent/US10221391B2/en active Active
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