JP5695562B2 - 安定化された経皮薬物送達システム - Google Patents

安定化された経皮薬物送達システム Download PDF

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Publication number
JP5695562B2
JP5695562B2 JP2011511876A JP2011511876A JP5695562B2 JP 5695562 B2 JP5695562 B2 JP 5695562B2 JP 2011511876 A JP2011511876 A JP 2011511876A JP 2011511876 A JP2011511876 A JP 2011511876A JP 5695562 B2 JP5695562 B2 JP 5695562B2
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therapeutic agent
adhesive
amorphous form
drug delivery
delivery device
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Japanese (ja)
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JP2011521974A5 (enExample
JP2011521974A (ja
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ターン，ジアシャーン
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マイラン・インコーポレーテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T156/00—Adhesive bonding and miscellaneous chemical manufacture
    • Y10T156/10—Methods of surface bonding and/or assembly therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2011511876A 2008-05-30 2009-05-29 安定化された経皮薬物送達システム Active JP5695562B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5745508P 2008-05-30 2008-05-30
US61/057,455 2008-05-30
PCT/US2009/045739 WO2009158120A2 (en) 2008-05-30 2009-05-29 Stabilized transdermal drug delivery system

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014232586A Division JP2015083569A (ja) 2008-05-30 2014-11-17 安定化された経皮薬物送達システム

Publications (3)

Publication Number Publication Date
JP2011521974A JP2011521974A (ja) 2011-07-28
JP2011521974A5 JP2011521974A5 (enExample) 2015-01-15
JP5695562B2 true JP5695562B2 (ja) 2015-04-08

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ID=41380695

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2011511876A Active JP5695562B2 (ja) 2008-05-30 2009-05-29 安定化された経皮薬物送達システム
JP2014232586A Pending JP2015083569A (ja) 2008-05-30 2014-11-17 安定化された経皮薬物送達システム

Family Applications After (1)

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JP2014232586A Pending JP2015083569A (ja) 2008-05-30 2014-11-17 安定化された経皮薬物送達システム

Country Status (11)

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US (2) US9226902B2 (enExample)
EP (1) EP2299989B1 (enExample)
JP (2) JP5695562B2 (enExample)
KR (1) KR101590209B1 (enExample)
CN (1) CN102099020B (enExample)
AU (2) AU2009262871B2 (enExample)
BR (1) BRPI0913214B1 (enExample)
CA (1) CA2726136C (enExample)
MX (1) MX2010012989A (enExample)
NZ (1) NZ589542A (enExample)
WO (1) WO2009158120A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015083569A (ja) * 2008-05-30 2015-04-30 マイラン・インコーポレーテッド 安定化された経皮薬物送達システム
WO2020189323A1 (ja) 2019-03-19 2020-09-24 ノーベルファーマ株式会社 薬物の生体への吸収性に優れ、且つ、化学的安定性にも優れる医薬組成物

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CN102665699A (zh) * 2009-12-22 2012-09-12 优时比制药有限公司 用于使非结晶形式的罗替戈汀的固体分散体稳定化的聚乙烯吡咯烷酮
WO2014028049A1 (en) * 2012-08-15 2014-02-20 Dow Corning Corporation Multi - layer transdermal drug delivery system
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US11752110B2 (en) * 2014-05-20 2023-09-12 Lts Lohmann Therapie-Systeme Ag Transdermal delivery system including an interface mediator
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CN112891324A (zh) * 2021-01-19 2021-06-04 北京亚宝生物药业有限公司 一种透皮贴剂
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015083569A (ja) * 2008-05-30 2015-04-30 マイラン・インコーポレーテッド 安定化された経皮薬物送達システム
WO2020189323A1 (ja) 2019-03-19 2020-09-24 ノーベルファーマ株式会社 薬物の生体への吸収性に優れ、且つ、化学的安定性にも優れる医薬組成物

Also Published As

Publication number Publication date
EP2299989B1 (en) 2019-01-02
US20090299304A1 (en) 2009-12-03
US20110182949A1 (en) 2011-07-28
NZ589542A (en) 2012-10-26
AU2009262871B2 (en) 2016-04-14
CA2726136A1 (en) 2009-12-30
JP2011521974A (ja) 2011-07-28
BRPI0913214B1 (pt) 2022-05-17
MX2010012989A (es) 2011-04-27
JP2015083569A (ja) 2015-04-30
AU2016202212B2 (en) 2018-05-10
CA2726136C (en) 2016-11-01
AU2009262871A1 (en) 2009-12-30
AU2016202212A1 (en) 2016-05-12
CN102099020B (zh) 2013-09-18
KR101590209B1 (ko) 2016-02-01
CN102099020A (zh) 2011-06-15
US9226902B2 (en) 2016-01-05
BRPI0913214A2 (pt) 2016-01-19
WO2009158120A2 (en) 2009-12-30
WO2009158120A3 (en) 2010-03-04
EP2299989A4 (en) 2013-11-13
EP2299989A2 (en) 2011-03-30
KR20110025931A (ko) 2011-03-14

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