CA2726136C - Stabilized transdermal drug delivery system - Google Patents
Stabilized transdermal drug delivery system Download PDFInfo
- Publication number
- CA2726136C CA2726136C CA2726136A CA2726136A CA2726136C CA 2726136 C CA2726136 C CA 2726136C CA 2726136 A CA2726136 A CA 2726136A CA 2726136 A CA2726136 A CA 2726136A CA 2726136 C CA2726136 C CA 2726136C
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- CA
- Canada
- Prior art keywords
- adhesive
- therapeutic agent
- solution
- release liner
- drug delivery
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
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- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
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- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
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- A—HUMAN NECESSITIES
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- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
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Landscapes
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- Bioinformatics & Cheminformatics (AREA)
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- Anesthesiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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| PCT/US2009/045739 WO2009158120A2 (en) | 2008-05-30 | 2009-05-29 | Stabilized transdermal drug delivery system |
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| CA2726136C (en) * | 2008-05-30 | 2016-11-01 | Mylan Laboratories, Inc. | Stabilized transdermal drug delivery system |
| KR101325104B1 (ko) * | 2009-09-16 | 2013-11-07 | 주식회사 삼양바이오팜 | 경피 투여 제형 및 그 제조 방법 |
| CN102665699A (zh) * | 2009-12-22 | 2012-09-12 | 优时比制药有限公司 | 用于使非结晶形式的罗替戈汀的固体分散体稳定化的聚乙烯吡咯烷酮 |
| WO2014028049A1 (en) * | 2012-08-15 | 2014-02-20 | Dow Corning Corporation | Multi - layer transdermal drug delivery system |
| TW201431570A (zh) | 2012-11-22 | 2014-08-16 | Ucb Pharma Gmbh | 用於經皮投服羅替戈汀（Ｒｏｔｉｇｏｔｉｎｅ）之多天式貼片 |
| JP2016135744A (ja) * | 2013-05-08 | 2016-07-28 | 株式会社 ケイ・エム トランスダーム | 貼付剤 |
| CA2916183C (en) | 2013-07-03 | 2022-03-29 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system with electronic component |
| WO2015025767A1 (ja) * | 2013-08-21 | 2015-02-26 | 久光製薬株式会社 | 貼付剤 |
| CN115444659A (zh) * | 2014-01-22 | 2022-12-09 | 4P治疗公司 | 滥用和误用制止透皮系统 |
| US11752110B2 (en) * | 2014-05-20 | 2023-09-12 | Lts Lohmann Therapie-Systeme Ag | Transdermal delivery system including an interface mediator |
| JP6573913B2 (ja) * | 2014-05-20 | 2019-09-11 | エルテーエス ローマン テラピー−ジステーメ アーゲー | ロチゴチンを含む経皮送達システム |
| CA2948219C (en) | 2014-05-20 | 2023-04-04 | Lts Lohmann Therapie-Systeme Ag | Method for adjusting the release of active agent in a transdermal delivery system |
| EP3197275B1 (en) * | 2014-09-24 | 2021-11-24 | Pain Therapeutics, Inc. | 4:3 naltrexone: 5-methyl-2-furaldehyde cocrystal |
| US10010543B1 (en) | 2014-12-23 | 2018-07-03 | Barr Laboratories, Inc. | Transdermal dosage form |
| US9650338B1 (en) | 2016-07-29 | 2017-05-16 | VDM Biochemicals, Inc. | Opioid antagonist compounds and methods of making and using |
| CN110087641B (zh) | 2016-12-20 | 2024-03-12 | 罗曼治疗系统股份公司 | 含有阿塞那平和聚硅氧烷或聚异丁烯的透皮治疗系统 |
| KR102506333B1 (ko) | 2016-12-20 | 2023-03-06 | 에르테에스 로만 테라피-시스테메 아게 | 아세나핀을 함유하는 경피흡수 치료 시스템 |
| KR102241892B1 (ko) | 2017-01-25 | 2021-04-20 | 한국전자기술연구원 | 백스캐터 통신을 위한 데이터 부호화 방법 및 이를 위한 장치 |
| KR20180121352A (ko) | 2017-04-28 | 2018-11-07 | 닛토덴코 가부시키가이샤 | 경피 흡수형 제제 |
| EP3644973B1 (en) | 2017-06-26 | 2021-03-24 | LTS LOHMANN Therapie-Systeme AG | Transdermal therapeutic system containing asenapine and silicone acrylic hybrid polymer |
| CN112533593A (zh) | 2018-06-20 | 2021-03-19 | 罗曼治疗系统股份公司 | 含有阿塞那平的透皮治疗系统 |
| CN112704672A (zh) | 2018-06-20 | 2021-04-27 | 罗曼治疗系统股份公司 | 含有阿塞那平的透皮治疗系统 |
| US20220117934A1 (en) * | 2019-02-15 | 2022-04-21 | Hisamitsu Pharmaceutical Co., Inc. | Rotigotine stabilization method |
| US20220160697A1 (en) * | 2019-03-19 | 2022-05-26 | Nobelpharma Co., Ltd. | Pharmaceutical composition having excellent drug absorption into the living body and excellent chemical stability |
| AU2020282832A1 (en) * | 2019-05-31 | 2022-02-03 | Kindeva Drug Delivery | Removable film-forming gel compositions featuring adhesion promoters |
| FI3854388T3 (fi) * | 2020-01-24 | 2023-11-27 | Luye Pharma Switzerland Ag | Transdermaalinen hoitojärjestelmä, jossa on vaikuttava aine rotigotiini ja ainakin yksi ei-amiiniresistentti silikoniliima |
| CA3193154A1 (en) * | 2020-08-31 | 2022-03-03 | Nobelpharma Co., Ltd. | Patch for alleviating or treating symptoms of neurodegenerative disease |
| CN112891324A (zh) * | 2021-01-19 | 2021-06-04 | 北京亚宝生物药业有限公司 | 一种透皮贴剂 |
| KR102363479B1 (ko) * | 2021-03-12 | 2022-02-15 | 환인제약 주식회사 | 로티고틴 함유 경피 흡수 제제 |
| EP4351536A1 (en) * | 2021-06-06 | 2024-04-17 | Starton Therapeutics, Inc. | Transdermal drug delivery systems for administration of a therapeutically effective amount of lenalidomide and other immunomodulatory agents |
| CN116270575A (zh) * | 2021-08-16 | 2023-06-23 | 乐明药业(苏州)有限公司 | 一种含有氟比洛芬的药物组合物与贴剂 |
| WO2024144130A1 (ko) * | 2022-12-26 | 2024-07-04 | 환인제약 주식회사 | 경피흡수용 제제 및 이의 제조 방법 |
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| WO2003034961A1 (en) | 2001-10-23 | 2003-05-01 | Euro-Celtique, S.A. | Terazosin transdermal device and methods |
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| ES2830073T3 (es) * | 2007-04-11 | 2021-06-02 | Omeros Corp | Composiciones y métodos para la profilaxis y el tratamiento de adicciones |
| CA2726136C (en) * | 2008-05-30 | 2016-11-01 | Mylan Laboratories, Inc. | Stabilized transdermal drug delivery system |
| BR112013021030A2 (pt) | 2011-02-17 | 2016-10-11 | Hoffmann La Roche | processo para cristalização controlada de um ingrediente farmacêutico ativo a partir de estado líquido super-refrigerado por extrusão por fusão a quente |
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2009
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- 2009-05-29 BR BRPI0913214-7A patent/BRPI0913214B1/pt active IP Right Grant
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- 2009-05-29 EP EP09770655.0A patent/EP2299989B1/en active Active
- 2009-05-29 US US12/475,390 patent/US9226902B2/en active Active
- 2009-05-29 WO PCT/US2009/045739 patent/WO2009158120A2/en not_active Ceased
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- 2009-05-29 MX MX2010012989A patent/MX2010012989A/es active IP Right Grant
- 2009-05-29 US US12/994,918 patent/US20110182949A1/en not_active Abandoned
- 2009-05-29 CN CN2009801289266A patent/CN102099020B/zh active Active
- 2009-05-29 JP JP2011511876A patent/JP5695562B2/ja active Active
- 2009-05-29 KR KR1020107029551A patent/KR101590209B1/ko active Active
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2014
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Also Published As
| Publication number | Publication date |
|---|---|
| EP2299989B1 (en) | 2019-01-02 |
| US20090299304A1 (en) | 2009-12-03 |
| JP5695562B2 (ja) | 2015-04-08 |
| US20110182949A1 (en) | 2011-07-28 |
| NZ589542A (en) | 2012-10-26 |
| AU2009262871B2 (en) | 2016-04-14 |
| CA2726136A1 (en) | 2009-12-30 |
| JP2011521974A (ja) | 2011-07-28 |
| BRPI0913214B1 (pt) | 2022-05-17 |
| MX2010012989A (es) | 2011-04-27 |
| JP2015083569A (ja) | 2015-04-30 |
| AU2016202212B2 (en) | 2018-05-10 |
| AU2009262871A1 (en) | 2009-12-30 |
| AU2016202212A1 (en) | 2016-05-12 |
| CN102099020B (zh) | 2013-09-18 |
| KR101590209B1 (ko) | 2016-02-01 |
| CN102099020A (zh) | 2011-06-15 |
| US9226902B2 (en) | 2016-01-05 |
| BRPI0913214A2 (pt) | 2016-01-19 |
| WO2009158120A2 (en) | 2009-12-30 |
| WO2009158120A3 (en) | 2010-03-04 |
| EP2299989A4 (en) | 2013-11-13 |
| EP2299989A2 (en) | 2011-03-30 |
| KR20110025931A (ko) | 2011-03-14 |
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