JP5695317B2 - 抗体媒介性ニューロパシーを処置するための方法および組成物 - Google Patents

抗体媒介性ニューロパシーを処置するための方法および組成物 Download PDF

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JP5695317B2
JP5695317B2 JP2009527404A JP2009527404A JP5695317B2 JP 5695317 B2 JP5695317 B2 JP 5695317B2 JP 2009527404 A JP2009527404 A JP 2009527404A JP 2009527404 A JP2009527404 A JP 2009527404A JP 5695317 B2 JP5695317 B2 JP 5695317B2
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antibody
composition
antigen
antibodies
complement
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JP2010502708A5 (https=
JP2010502708A (ja
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スーザン ハルステッド，
スーザン ハルステッド，
ヒュー ウィルソン，
ヒュー ウィルソン，
ラッセル ピー． ロザー，
ラッセル ピー． ロザー，
Original Assignee
アレクシオン ファーマシューティカルズ， インコーポレイテッド
アレクシオン ファーマシューティカルズ， インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2009527404A 2006-09-05 2007-09-05 抗体媒介性ニューロパシーを処置するための方法および組成物 Expired - Fee Related JP5695317B2 (ja)

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US84229606P 2006-09-05 2006-09-05
US60/842,296 2006-09-05
PCT/US2007/019416 WO2008030505A2 (en) 2006-09-05 2007-09-05 Methods and compositions for the treatment of antibody mediated neuropathies

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JP2014196133A Division JP2014240438A (ja) 2006-09-05 2014-09-26 抗体媒介性ニューロパシーを処置するための方法および組成物

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JP2010502708A JP2010502708A (ja) 2010-01-28
JP2010502708A5 JP2010502708A5 (https=) 2011-08-11
JP5695317B2 true JP5695317B2 (ja) 2015-04-01

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JP2014196133A Pending JP2014240438A (ja) 2006-09-05 2014-09-26 抗体媒介性ニューロパシーを処置するための方法および組成物

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US (1) US9388235B2 (https=)
EP (4) EP3199549A1 (https=)
JP (2) JP5695317B2 (https=)
KR (1) KR101503540B1 (https=)
AU (1) AU2007293013B2 (https=)
BR (1) BRPI0715869A2 (https=)
CA (1) CA2662480C (https=)
DK (1) DK2061810T3 (https=)
ES (2) ES2616204T3 (https=)
IL (1) IL197148A (https=)
MX (1) MX2009002426A (https=)
NZ (1) NZ575018A (https=)
PL (1) PL2061810T3 (https=)
PT (1) PT2061810E (https=)
SI (1) SI2061810T1 (https=)
WO (1) WO2008030505A2 (https=)

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Also Published As

Publication number Publication date
EP3199549A1 (en) 2017-08-02
EP2913342A1 (en) 2015-09-02
AU2007293013B2 (en) 2013-06-27
KR20090051063A (ko) 2009-05-20
EP2061810A2 (en) 2009-05-27
KR101503540B1 (ko) 2015-03-17
ES2616204T3 (es) 2017-06-09
SI2061810T1 (sl) 2015-04-30
MX2009002426A (es) 2009-03-20
BRPI0715869A2 (pt) 2013-07-30
WO2008030505A3 (en) 2008-06-19
CA2662480C (en) 2016-11-08
WO2008030505A2 (en) 2008-03-13
IL197148A (en) 2016-06-30
US9388235B2 (en) 2016-07-12
JP2014240438A (ja) 2014-12-25
HK1126793A1 (en) 2009-09-11
CA2662480A1 (en) 2008-03-13
NZ575018A (en) 2012-04-27
US20100143343A1 (en) 2010-06-10
ES2530428T3 (es) 2015-03-02
WO2008030505A8 (en) 2009-03-05
IL197148A0 (en) 2011-08-01
PT2061810E (pt) 2015-02-05
EP2380907B1 (en) 2016-11-30
EP2380907A1 (en) 2011-10-26
DK2061810T3 (en) 2015-02-16
AU2007293013A1 (en) 2008-03-13
PL2061810T3 (pl) 2015-05-29
JP2010502708A (ja) 2010-01-28
EP2061810B1 (en) 2014-11-12

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