JP5693245B2 - 皮膚外用剤 - Google Patents
皮膚外用剤 Download PDFInfo
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- JP5693245B2 JP5693245B2 JP2011001095A JP2011001095A JP5693245B2 JP 5693245 B2 JP5693245 B2 JP 5693245B2 JP 2011001095 A JP2011001095 A JP 2011001095A JP 2011001095 A JP2011001095 A JP 2011001095A JP 5693245 B2 JP5693245 B2 JP 5693245B2
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Landscapes
- Cosmetics (AREA)
Description
しかしながら、マンノシルエリスリトールリピッドのみでは水への分散性が低く、化粧水のような低粘度の水性の皮膚外用剤を形成しづらいため、クリーム又は乳液の形態といった製剤上の制限があった。また、マンノシルエリスリトールリピッドはエタノールへの溶解性があることから、エタノールを多量に用いた製剤(育毛・養毛剤)が開発されている(特許文献3参照)が、エタノールの刺激性から、皮膚外用剤としては利用しにくいという問題があった。
(A)HLBが10以上のポリオキシエチレン硬化ヒマシ油
(B)マンノシルエリスリトールリピッド 0.01〜4質量%
R1、R2の好ましい基としては、CH3(CH2)6、CH3(CH2)8、CH3(CH2)10などのC7〜C11のアルキル基;C7H14、C9H18、C11H22などのC7〜C11のアルケニル基;C7H12、C9H16、C11H20などのC7〜C11のアルカジエニル基;C7H10、C9H14、C11H18などのC7〜C11のアルカトリエニル基が挙げられる。
ここで、油剤は、油脂(トリグリセリド)、エステル油、炭化水素、炭素数8以上の高級アルコール、シリコーン油、フッ素油等の油分へ溶解しやすい成分の総体である。
試料調製後、透明ガラス瓶に常温で1月間保存し、外観を目視にて観察し、沈殿、分離、析出等の異常が見られない場合に「○」、異常が見られた場合を「×」として評価を行った。
〔外観評価試験〕
前記経時安定性評価時に、厚さ3cmの透明ガラス瓶を通して後ろの文字を認識できるかにより、透明度を観察し、透明清澄(8ポイントの文字をはっきりと認識できる)の場合を「◎」、透明白濁(12ポイントの文字を認識できる)の場合を「○」、白濁(12ポイントの文字を認識できない)の場合を「△」として評価を行った。尚、前記経時安定性にて、異常が見られた場合には評価を行わなかった。
〔官能試験〕
成人女性20名の評価パネラーに試料を使用してもらい、使用後に塗布後のさっぱり感、保湿感に関し、良いと答えた人数で評価した。また、原料臭の有無に関し、原料臭を特に感じないと答えた人数で評価した。
表1、2に記載の組成で化粧水を調製し、前記の経時安定性試験、外観試験、官能試験を実施した。
各成分を室温にて均一に混合攪拌する。
実施例及び比較例の製造直後の官能試験結果を表1、2に合わせて示す。
表1、2に示すように、本発明の実施例1〜12の化粧水は、透明性を有し、経時安定性に優れたものであった。また、さっぱり感、保湿感が良好であり、使用感の優れたものであった。一方、比較例1〜12では全て、沈殿が生じてしまっており、官能評価を実施しなかった。
表3に記載の成分を常温にて均一に混合攪拌し、化粧水を調製した。
表4に記載の成分を常温にて均一に混合攪拌し、化粧水を調製した。
表5に記載の成分を常温にて均一に混合攪拌し、化粧水を調製した。
表6に記載の成分を常温にて均一に混合攪拌し、化粧水を調製した。
Claims (5)
- 成分(A)と成分(B)の含有比率〔(A)/(B)〕が、0.2〜0.6である請求項1に記載の皮膚外用剤。
- さらに、(C)エタノールを15質量%以下で含有する請求項1又は2に記載の皮膚外用剤。
- 油剤を実質的に含まないものである請求項1〜3のいずれか1項に記載の皮膚外用剤。
- 25℃における粘度が、10000mPa・s以下である請求項1〜4のいずれか1項
に記載の皮膚外用剤。
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JP6022268B2 (ja) * | 2012-09-07 | 2016-11-09 | 日本メナード化粧品株式会社 | 粉末化粧料 |
KR20160040969A (ko) | 2014-10-06 | 2016-04-15 | (주)아모레퍼시픽 | 알파인 웜우드 추출물을 포함하는 탈모 방지 또는 육모 촉진용 조성물 |
JP6158864B2 (ja) * | 2015-06-30 | 2017-07-05 | 花王株式会社 | 水性化粧料 |
KR20180028131A (ko) * | 2016-09-08 | 2018-03-16 | (주)아모레퍼시픽 | 만노실에리트리톨 지질을 함유하는 피부 미백용 조성물 |
JP6735268B2 (ja) * | 2017-12-28 | 2020-08-05 | 花王株式会社 | 用時混合型化粧料 |
WO2023192979A2 (en) * | 2022-03-31 | 2023-10-05 | Locus Solutions Ipco, Llc | Compositions and methods for promoting hair growth |
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JP2011225453A (ja) * | 2010-04-15 | 2011-11-10 | Toyobo Co Ltd | 皮膚化粧料 |
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