JP5690826B2 - 多層状勾配膣リング - Google Patents
多層状勾配膣リング Download PDFInfo
- Publication number
- JP5690826B2 JP5690826B2 JP2012521631A JP2012521631A JP5690826B2 JP 5690826 B2 JP5690826 B2 JP 5690826B2 JP 2012521631 A JP2012521631 A JP 2012521631A JP 2012521631 A JP2012521631 A JP 2012521631A JP 5690826 B2 JP5690826 B2 JP 5690826B2
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- JP
- Japan
- Prior art keywords
- regions
- vaginal ring
- pharmaceutically active
- region
- active ingredient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- ICMWWNHDUZJFDW-UHFFFAOYSA-N oxymetholone Natural products C1CC2CC(=O)C(=CO)CC2(C)C2C1C1CCC(C)(O)C1(C)CC2 ICMWWNHDUZJFDW-UHFFFAOYSA-N 0.000 description 1
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- 239000008194 pharmaceutical composition Substances 0.000 description 1
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Gynecology & Obstetrics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27139109P | 2009-07-21 | 2009-07-21 | |
| US61/271,391 | 2009-07-21 | ||
| PCT/US2010/030183 WO2011011099A1 (en) | 2009-07-21 | 2010-04-07 | Multi-layered gradient vaginal ring |
Publications (2)
| Publication Number | Publication Date |
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| JP2012533401A JP2012533401A (ja) | 2012-12-27 |
| JP5690826B2 true JP5690826B2 (ja) | 2015-03-25 |
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| JP2012521631A Active JP5690826B2 (ja) | 2009-07-21 | 2010-04-07 | 多層状勾配膣リング |
Country Status (14)
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| GB0222522D0 (en) | 2002-09-27 | 2002-11-06 | Controlled Therapeutics Sct | Water-swellable polymers |
| GB0417401D0 (en) | 2004-08-05 | 2004-09-08 | Controlled Therapeutics Sct | Stabilised prostaglandin composition |
| GB0613333D0 (en) | 2006-07-05 | 2006-08-16 | Controlled Therapeutics Sct | Hydrophilic polyurethane compositions |
| US8580294B2 (en) | 2010-10-19 | 2013-11-12 | International Partnership For Microbicides | Platinum-catalyzed intravaginal rings |
| DE202011110355U1 (de) * | 2011-03-09 | 2014-01-15 | Arstat, Inc. | Behandlung von Uterusmyomen durch intravaginale Verabreichung einer niedrigen Dosis eines selektiven Progesteronrezeptormodulators, eines Antigestagens oder eines Antigestagen-Wirkstoffes |
| FR3005417B1 (fr) * | 2013-05-10 | 2015-05-22 | Blaise Francois Figuereo | Anneau vaginal tri-reservoir, a retro-largage compatible avec les caracteristiques des molecules actives qu'il contient |
| US10137031B2 (en) | 2013-11-14 | 2018-11-27 | International Partnership For Microbicides, Inc. | Combination therapy intravaginal rings |
| US10413504B2 (en) * | 2013-12-11 | 2019-09-17 | Merck Sharp & Dohme Corp. | Intravaginal ring drug delivery system |
| HUE040176T2 (hu) | 2014-06-28 | 2019-02-28 | Laboratorios Andromaco S A | Elnyújtott, hosszantartó és folyamatos felszabadulású progeszteront tartalmazó méhnyakpesszárium koraszülés megelõzésére |
| US9943146B2 (en) | 2015-05-27 | 2018-04-17 | Qalo Llc | Compression molded silicone ring |
| CA2984032C (en) * | 2015-07-14 | 2019-10-08 | Qalo Llc | Compression molded silicone ring |
| SG11201805114RA (en) * | 2015-12-21 | 2018-07-30 | Bayer Oy | Method for manufacturing a drug delivery device and a drug delivery device manufactured according to the method |
| EP3272333A1 (en) | 2016-07-22 | 2018-01-24 | Chemo Research, S.L. | Vaginal composition comprising a combination of estrogen and vitamin d |
| CN106913412B (zh) * | 2017-03-01 | 2023-09-22 | 上海市嘉定区妇幼保健院 | 易放易取式子宫托 |
| EP3801462A4 (en) | 2018-05-24 | 2022-03-16 | Celanese EVA Performance Polymers LLC | Implantable device for sustained release of a macromolecular drug compound |
| EP3803866A4 (en) | 2018-05-24 | 2022-03-16 | Nureva Inc. | METHOD, APPARATUS, AND COMPUTER READABLE MATERIALS FOR MANAGING SEMI-CONSTANT (PERSISTENT) SOUND SOURCES IN MICROPHONE CATCH/HOME AREAS |
| CN111989068B (zh) | 2018-05-24 | 2024-10-25 | 塞拉尼斯伊娃高性能聚合物公司 | 用于持续释放大分子药物化合物的可植入器件 |
| US10918649B2 (en) | 2019-06-21 | 2021-02-16 | The Population Council, Inc. | System for providing birth control |
| KR20220101660A (ko) * | 2019-11-12 | 2022-07-19 | 폴리-메드, 인코포레이티드 | 피임 의료 장치 |
| DE102021100916A1 (de) | 2021-01-18 | 2022-07-21 | Carl Freudenberg Kg | Verfahren zur Herstellung eines Bauteils, Werkzeug zur Durchführung des Verfahrens und Bauteil, das durch das Verfahren hergestellt ist |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL152819B (nl) | 1949-04-07 | Swift & Co | Werkwijze voor het continu bereiden van mono-ammoniumdiwaterstoffosfaatdeeltjes en zo verkregen deeltjes. | |
| US2863846A (en) | 1950-05-04 | 1958-12-09 | Dow Corning | Organo silyl-silica filled siloxane elastomers and process for producing same |
| US2890188A (en) | 1951-12-17 | 1959-06-09 | Dow Corning | Siloxane elastomers compounded with hydroxylated silanes |
| NL91756C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1953-11-19 | |||
| GB804199A (en) | 1955-12-22 | 1958-11-12 | Midland Silicones Ltd | Organosiloxane compositions |
| GB798669A (en) | 1956-12-12 | 1958-07-23 | Midland Silicones Ltd | Improvements in or relating to organosiloxane elastomer foams |
| US2927907A (en) | 1957-01-07 | 1960-03-08 | Dow Corning | Siloxane elastomers |
| US3022951A (en) | 1957-05-14 | 1962-02-27 | Ibm | Full adder |
| US3035016A (en) | 1959-03-16 | 1962-05-15 | Dow Corning | Acyloxy siloxanes and a method of using the |
| US3545439A (en) | 1968-01-04 | 1970-12-08 | Upjohn Co | Medicated devices and methods |
| US4155991A (en) | 1974-10-18 | 1979-05-22 | Schering Aktiengesellschaft | Vaginal ring |
| IL48277A (en) | 1974-10-18 | 1978-03-10 | Schering Ag | Vaginal ring |
| US3995634A (en) | 1975-12-02 | 1976-12-07 | The Procter & Gamble Company | Vaginal cavity dispensing means and method |
| US3995633A (en) | 1975-12-02 | 1976-12-07 | The Procter & Gamble Company | Vaginal Medicament dispensing device |
| US4237885A (en) | 1978-10-23 | 1980-12-09 | Alza Corporation | Delivery system with mated members for storing and releasing a plurality of beneficial agents |
| US4292965A (en) * | 1978-12-29 | 1981-10-06 | The Population Council, Inc. | Intravaginal ring |
| DE3040978A1 (de) | 1980-10-28 | 1982-05-27 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Vaginalring |
| US4596576A (en) | 1984-10-12 | 1986-06-24 | Akzo N.V. | Release system for two or more active substances |
| FR2598652B1 (fr) | 1986-05-16 | 1988-08-05 | Figuereo Blaise | Machine d'extrusion simultanee de plusieurs matieres |
| US4922928A (en) | 1988-08-17 | 1990-05-08 | Michael Burnhill | Vaginal device |
| DE69616551T2 (de) | 1995-07-04 | 2002-05-29 | Akzo Nobel N.V., Arnheim/Arnhem | Ringförmige vorrichtung |
| US5972372A (en) * | 1996-07-31 | 1999-10-26 | The Population Council, Inc. | Intravaginal rings with insertable drug-containing core |
| IL123813A0 (en) | 1997-04-11 | 1998-10-30 | Akzo Nobel Nv | Drug delivery system for two or more active substances |
| US6951654B2 (en) | 2001-03-27 | 2005-10-04 | Galen (Chemicals) Limited | Intravaginal drug delivery devices for the administration of an antimicrobial agent |
| AU2004233997C1 (en) | 2003-04-29 | 2014-01-30 | Massachusetts Institiute Of Technology | Methods and devices for the sustained release of multiple drugs |
| TWI336627B (en) * | 2003-05-23 | 2011-02-01 | Organon Nv | Drug delivery system,and use and manufacturing method thereof |
| CN1899643B (zh) | 2005-07-20 | 2010-12-29 | 上海市计划生育科学研究所 | 含有抗雌激素和抗孕激素复合制剂的阴道环或宫内释药装置及其制药用途 |
| US7824383B2 (en) | 2006-06-16 | 2010-11-02 | Family Health International | Vaginal drug delivery system and method |
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- 2010-04-07 JP JP2012521631A patent/JP5690826B2/ja active Active
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- 2010-04-07 WO PCT/US2010/030183 patent/WO2011011099A1/en active Application Filing
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| AU2010274946B2 (en) | 2013-09-12 |
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| BR112012001353B1 (pt) | 2020-04-14 |
| JP2012533401A (ja) | 2012-12-27 |
| US20120148655A1 (en) | 2012-06-14 |
| AU2010274946A1 (en) | 2012-03-01 |
| CO6491080A2 (es) | 2012-07-31 |
| HK1169614A1 (en) | 2013-02-01 |
| DK2456421T3 (en) | 2017-06-06 |
| WO2011011099A1 (en) | 2011-01-27 |
| CA2767967C (en) | 2014-10-21 |
| BR112012001353B8 (pt) | 2021-05-25 |
| MX2012000948A (es) | 2012-02-28 |
| CN102497855A (zh) | 2012-06-13 |
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