JP5680878B2 - 光学活性アルコールの製造方法 - Google Patents
光学活性アルコールの製造方法 Download PDFInfo
- Publication number
- JP5680878B2 JP5680878B2 JP2010111120A JP2010111120A JP5680878B2 JP 5680878 B2 JP5680878 B2 JP 5680878B2 JP 2010111120 A JP2010111120 A JP 2010111120A JP 2010111120 A JP2010111120 A JP 2010111120A JP 5680878 B2 JP5680878 B2 JP 5680878B2
- Authority
- JP
- Japan
- Prior art keywords
- group
- optically active
- active alcohol
- water
- ketone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B53/00—Asymmetric syntheses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/15—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of oxides of carbon exclusively
- C07C29/151—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of oxides of carbon exclusively with hydrogen or hydrogen-containing gases
- C07C29/153—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of oxides of carbon exclusively with hydrogen or hydrogen-containing gases characterised by the catalyst used
- C07C29/156—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of oxides of carbon exclusively with hydrogen or hydrogen-containing gases characterised by the catalyst used containing iron group metals, platinum group metals or compounds thereof
- C07C29/157—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of oxides of carbon exclusively with hydrogen or hydrogen-containing gases characterised by the catalyst used containing iron group metals, platinum group metals or compounds thereof containing platinum group metals or compounds thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pyrane Compounds (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010111120A JP5680878B2 (ja) | 2010-05-13 | 2010-05-13 | 光学活性アルコールの製造方法 |
| US13/104,156 US9162934B2 (en) | 2010-05-13 | 2011-05-10 | Process for producing optically active alcohol |
| EP20110003944 EP2394977B1 (en) | 2010-05-13 | 2011-05-12 | Process for producing optically active alcohol |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010111120A JP5680878B2 (ja) | 2010-05-13 | 2010-05-13 | 光学活性アルコールの製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011236180A JP2011236180A (ja) | 2011-11-24 |
| JP2011236180A5 JP2011236180A5 (enExample) | 2013-06-06 |
| JP5680878B2 true JP5680878B2 (ja) | 2015-03-04 |
Family
ID=44860631
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010111120A Active JP5680878B2 (ja) | 2010-05-13 | 2010-05-13 | 光学活性アルコールの製造方法 |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US9162934B2 (enExample) |
| EP (1) | EP2394977B1 (enExample) |
| JP (1) | JP5680878B2 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107641072B (zh) * | 2016-07-22 | 2020-07-21 | 江苏威凯尔医药科技有限公司 | 一种制备(s)-2-氯-1-(3,4-二氟苯基)乙醇的方法 |
| CN113443958A (zh) * | 2020-03-26 | 2021-09-28 | 凯特立斯(深圳)科技有限公司 | 一种替格瑞洛重要中间体的制备方法 |
| CN116410095B (zh) * | 2021-12-29 | 2025-06-03 | 凯特立斯(深圳)科技有限公司 | 一种盐酸去氧肾上腺素的合成方法 |
| CN118724858B (zh) * | 2023-03-31 | 2025-09-19 | 上海医药工业研究院有限公司 | 一种(r)-苯并吡喃-4-醇类化合物的制备方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2962668B2 (ja) | 1995-12-06 | 1999-10-12 | 科学技術振興事業団 | 光学活性アルコール類の製造方法 |
| EP0916637B1 (en) | 1995-12-06 | 2005-04-20 | Japan Science and Technology Agency | Process for preparating optically active compounds |
| GB9706321D0 (en) | 1997-03-26 | 1997-05-14 | Zeneca Ltd | Catalytic hydrogenation |
| US6888012B2 (en) * | 2000-12-25 | 2005-05-03 | Ajinomoto Co., Inc. | Process for producing optically active halohydrin compound |
| JP4425654B2 (ja) * | 2004-02-03 | 2010-03-03 | 高砂香料工業株式会社 | 水溶性遷移金属−ジアミン錯体、及びその製造方法、並びにその用途 |
| JP4718452B2 (ja) * | 2004-03-29 | 2011-07-06 | 高砂香料工業株式会社 | 光学活性遷移金属−ジアミン錯体及びこれを用いた光学活性アルコール類の製造方法 |
| WO2006137167A1 (ja) * | 2005-06-20 | 2006-12-28 | Kanto Kagaku Kabushiki Kaisha | スルホナート触媒及びそれを利用したアルコール化合物の製法 |
| CN101104614A (zh) | 2007-05-30 | 2008-01-16 | 中山大学 | (s)-度洛西汀关键中间体的制备方法 |
| JP2009023941A (ja) | 2007-07-19 | 2009-02-05 | Kanto Chem Co Inc | 有機金属化合物及びそれを用いた光学活性アルコール類の製造方法 |
| JP5727127B2 (ja) * | 2009-04-10 | 2015-06-03 | 関東化学株式会社 | 不斉触媒およびこれを用いた光学活性アルコール類の製造方法 |
-
2010
- 2010-05-13 JP JP2010111120A patent/JP5680878B2/ja active Active
-
2011
- 2011-05-10 US US13/104,156 patent/US9162934B2/en not_active Expired - Fee Related
- 2011-05-12 EP EP20110003944 patent/EP2394977B1/en not_active Revoked
Also Published As
| Publication number | Publication date |
|---|---|
| US20110282077A1 (en) | 2011-11-17 |
| US9162934B2 (en) | 2015-10-20 |
| EP2394977B1 (en) | 2014-01-08 |
| JP2011236180A (ja) | 2011-11-24 |
| EP2394977A1 (en) | 2011-12-14 |
| EP2394977A8 (en) | 2012-01-18 |
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