JP5678034B2 - アレルゲン駆動性気道病態の予防または治療のためのワクチン - Google Patents

アレルゲン駆動性気道病態の予防または治療のためのワクチン Download PDF

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JP5678034B2
JP5678034B2 JP2012507703A JP2012507703A JP5678034B2 JP 5678034 B2 JP5678034 B2 JP 5678034B2 JP 2012507703 A JP2012507703 A JP 2012507703A JP 2012507703 A JP2012507703 A JP 2012507703A JP 5678034 B2 JP5678034 B2 JP 5678034B2
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pertussis
ova
bpze1
attenuated
allergen
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JP2012525346A (ja
JP2012525346A5 (enExample
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ロシュ，カミール
マホン，バーナード
カヴァナー，ヘザー
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National University of Ireland Maynooth
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/099—Bordetella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/544—Mucosal route to the airways

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2012507703A 2009-04-28 2010-04-26 アレルゲン駆動性気道病態の予防または治療のためのワクチン Active JP5678034B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09305371 2009-04-28
EP09305371.8 2009-04-28
PCT/EP2010/055507 WO2010125014A1 (en) 2009-04-28 2010-04-26 Vaccine for prophylaxis or treatment of an allergen-driven airway pathology

Publications (3)

Publication Number Publication Date
JP2012525346A JP2012525346A (ja) 2012-10-22
JP2012525346A5 JP2012525346A5 (enExample) 2013-05-02
JP5678034B2 true JP5678034B2 (ja) 2015-02-25

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JP2012507703A Active JP5678034B2 (ja) 2009-04-28 2010-04-26 アレルゲン駆動性気道病態の予防または治療のためのワクチン

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US (7) US20120177688A1 (enExample)
EP (3) EP3590532B1 (enExample)
JP (1) JP5678034B2 (enExample)
CN (1) CN102448490B (enExample)
AU (1) AU2010243708C1 (enExample)
CA (1) CA2759280C (enExample)
DK (1) DK2424564T3 (enExample)
ES (2) ES3024937T3 (enExample)
SG (1) SG175803A1 (enExample)
WO (1) WO2010125014A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2821830T3 (es) 2006-03-10 2021-04-27 Pasteur Institut Cepas de Bordetella vivas atenuadas como vacuna de dosis única contra la tos ferina
CA2759280C (en) 2009-04-28 2016-09-20 Inserm (Institut National De La Sante Et De La Recherche Medicale) Vaccine for prophylaxis or treatment of an allergen-driven airway pathology
EP2442826B1 (en) 2009-06-15 2015-07-08 National University of Singapore Influenza vaccine, composition, and methods of use
CN104302314B (zh) * 2011-11-02 2020-06-02 新加坡国立大学 减毒博代氏杆菌菌株对抗变应性疾病的效果
EP2722338A1 (en) 2012-10-17 2014-04-23 INSERM (Institut National de la Santé et de la Recherche Médicale) Novel recombinant Bordetella strains
EP3033108B1 (en) 2013-08-16 2021-03-24 University Of Rochester Designed peptides for tight junction barrier modulation
US9655959B2 (en) * 2014-10-01 2017-05-23 National University Of Singapore Adenylate cyclase deficient bordetella strains
DK3436034T3 (da) * 2016-03-29 2025-05-12 Pasteur Institut Muterede bordetella-stammer og fremgangsmåder til brug
JP6598724B2 (ja) 2016-04-07 2019-10-30 株式会社ジェイテクト ステアリング装置
WO2019077028A1 (en) 2017-10-18 2019-04-25 Institut Pasteur De Lille BORDETELLA STRAINS EXPRESSING SERO-TYPE FIMBRIAE 3
WO2020247347A1 (en) 2019-06-05 2020-12-10 University Of Rochester New designed inhibitors of tight junction formation
US20250263447A1 (en) * 2020-09-04 2025-08-21 Intravacc B.V. Ompa mutations enhance omv production in bordetella pertussis
EP3909971A1 (en) 2020-09-28 2021-11-17 Institute of Life Sciences (ILS) Whole cell livestock vaccine for respiratory diseases

Family Cites Families (22)

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US4883761A (en) 1986-03-25 1989-11-28 The United States Of America As Represented By The Department Of Health And Human Services Pertussis toxin gene: cloning and expression of protective antigen
US5101019A (en) * 1987-05-22 1992-03-31 Takeda Chemical Industries, Ltd. Method for removing pertussis endotoxin, a pertussis toxoid and its production
US6713072B1 (en) 1987-11-02 2004-03-30 Chiron S.R.L. Immunologically active polypeptides with altered toxicity useful for the preparation of an antipertussis vaccine
GB9115332D0 (en) 1991-07-16 1991-08-28 Connaught Lab Manipulation of gene copy number in bordetella
FR2754543B1 (fr) 1996-10-11 1998-12-31 Pasteur Institut Souche de bordetella deficiente dans la production de toxine et exprimant une proteine hydride, liposomes comprenant de la fha et leurs utilisations comme vaccins, et utilisation de la fha pour stimuler les reponses immunitaires
FR2840319B1 (fr) * 2002-05-30 2004-08-20 Pasteur Institut Souches de bordetella rendues deficientes par attenuation genetique
WO2004091519A2 (en) * 2003-04-11 2004-10-28 Medimmune, Inc. Methods of preventing or treating respiratory conditions
GB0402131D0 (en) 2004-01-30 2004-03-03 Isis Innovation Delivery method
ES2821830T3 (es) * 2006-03-10 2021-04-27 Pasteur Institut Cepas de Bordetella vivas atenuadas como vacuna de dosis única contra la tos ferina
US20080254062A1 (en) 2007-02-23 2008-10-16 The Penn State Research Foundation Use of an avirulent bordetella mutant as a live vaccine vector
CN100537767C (zh) * 2007-04-29 2009-09-09 中国药品生物制品检定所 百日咳疫苗保护性抗原的重组表达及其应用
CA2759280C (en) 2009-04-28 2016-09-20 Inserm (Institut National De La Sante Et De La Recherche Medicale) Vaccine for prophylaxis or treatment of an allergen-driven airway pathology
CN101947323B (zh) * 2010-07-26 2013-02-27 北京绿竹生物制药有限公司 一种革兰氏阴性细菌疫苗及其制备方法
CN104302314B (zh) 2011-11-02 2020-06-02 新加坡国立大学 减毒博代氏杆菌菌株对抗变应性疾病的效果
EP2722338A1 (en) 2012-10-17 2014-04-23 INSERM (Institut National de la Santé et de la Recherche Médicale) Novel recombinant Bordetella strains
US9655959B2 (en) 2014-10-01 2017-05-23 National University Of Singapore Adenylate cyclase deficient bordetella strains
DK3436034T3 (da) 2016-03-29 2025-05-12 Pasteur Institut Muterede bordetella-stammer og fremgangsmåder til brug
US10799573B2 (en) 2016-03-30 2020-10-13 Regents Of The University Of Minnesota Pertussis vaccines and methods of making and using
US20200171169A1 (en) 2017-05-15 2020-06-04 Vanderbilt University LONG-CIRCULATING ZWITTERIONIC POLYPLEXES FOR siRNA DELIVERY
KR102657910B1 (ko) 2017-07-18 2024-04-18 세럼 인스티튜트 오브 인디아 프라이비트 리미티드 개선된 안정성, 강화된 면역원성과 감소된 반응원성을 갖는 면역원성 조성물 및 그의 제조 방법
WO2019077028A1 (en) 2017-10-18 2019-04-25 Institut Pasteur De Lille BORDETELLA STRAINS EXPRESSING SERO-TYPE FIMBRIAE 3
US12036405B2 (en) 2018-03-23 2024-07-16 The Board Of Regents Of The University Of Oklahoma System and method of electric-induced acoustic tomography for electrotherapy monitoring

Also Published As

Publication number Publication date
DK2424564T3 (en) 2015-04-27
US20200282041A1 (en) 2020-09-10
SG175803A1 (en) 2011-12-29
EP2424564A1 (en) 2012-03-07
US20150182614A1 (en) 2015-07-02
US9839683B2 (en) 2017-12-12
ES2535412T3 (es) 2015-05-11
US20180085450A1 (en) 2018-03-29
AU2010243708A1 (en) 2011-11-03
US20210361759A1 (en) 2021-11-25
CN102448490A (zh) 2012-05-09
CA2759280A1 (en) 2010-11-04
US20190358309A1 (en) 2019-11-28
ES3024937T3 (en) 2025-06-05
JP2012525346A (ja) 2012-10-22
US11819545B2 (en) 2023-11-21
US10420827B2 (en) 2019-09-24
EP3590532A1 (en) 2020-01-08
EP3590532B1 (en) 2025-03-19
AU2010243708C1 (en) 2014-10-02
US11110161B2 (en) 2021-09-07
US20130183336A1 (en) 2013-07-18
US10653765B2 (en) 2020-05-19
AU2010243708B2 (en) 2014-06-12
CN102448490B (zh) 2015-05-13
EP2424564B1 (en) 2015-02-25
WO2010125014A1 (en) 2010-11-04
US20120177688A1 (en) 2012-07-12
CA2759280C (en) 2016-09-20
EP2910252A1 (en) 2015-08-26
EP3590532C0 (en) 2025-03-19
US8986709B2 (en) 2015-03-24

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