DK2424564T3 - A vaccine for the prevention or treatment of a respiratory pathology allergendrevet - Google Patents

A vaccine for the prevention or treatment of a respiratory pathology allergendrevet Download PDF

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Publication number
DK2424564T3
DK2424564T3 DK10715245T DK10715245T DK2424564T3 DK 2424564 T3 DK2424564 T3 DK 2424564T3 DK 10715245 T DK10715245 T DK 10715245T DK 10715245 T DK10715245 T DK 10715245T DK 2424564 T3 DK2424564 T3 DK 2424564T3
Authority
DK
Denmark
Prior art keywords
pertussis
ova
live attenuated
bpze1
bordetella pertussis
Prior art date
Application number
DK10715245T
Other languages
Danish (da)
English (en)
Inventor
Bernard Mahon
Heather Kavanagh
Camille Locht
Original Assignee
Inserm Inst Nat De La Santé Et De La Rech Médicale
Pasteur Institut
Nat Univ Ireland Maynooth
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inserm Inst Nat De La Santé Et De La Rech Médicale, Pasteur Institut, Nat Univ Ireland Maynooth filed Critical Inserm Inst Nat De La Santé Et De La Rech Médicale
Application granted granted Critical
Publication of DK2424564T3 publication Critical patent/DK2424564T3/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/099Bordetella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/543Mucosal route intranasal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/544Mucosal route to the airways

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK10715245T 2009-04-28 2010-04-26 A vaccine for the prevention or treatment of a respiratory pathology allergendrevet DK2424564T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09305371 2009-04-28
PCT/EP2010/055507 WO2010125014A1 (en) 2009-04-28 2010-04-26 Vaccine for prophylaxis or treatment of an allergen-driven airway pathology

Publications (1)

Publication Number Publication Date
DK2424564T3 true DK2424564T3 (en) 2015-04-27

Family

ID=41057387

Family Applications (1)

Application Number Title Priority Date Filing Date
DK10715245T DK2424564T3 (en) 2009-04-28 2010-04-26 A vaccine for the prevention or treatment of a respiratory pathology allergendrevet

Country Status (10)

Country Link
US (7) US20120177688A1 (enExample)
EP (3) EP2424564B1 (enExample)
JP (1) JP5678034B2 (enExample)
CN (1) CN102448490B (enExample)
AU (1) AU2010243708C1 (enExample)
CA (1) CA2759280C (enExample)
DK (1) DK2424564T3 (enExample)
ES (2) ES3024937T3 (enExample)
SG (1) SG175803A1 (enExample)
WO (1) WO2010125014A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007224734C1 (en) 2006-03-10 2016-07-14 Institut National De La Sante Et De La Recherche Medicale (Inserm) Live attenuated Bordetella strains as a single dose vaccine against whooping cough
US20120177688A1 (en) 2009-04-28 2012-07-12 Institut Pasteur De Lille Vaccine for Prophylaxis or Treatment of an Allergen-Driven Airway Pathology
EP2944320A1 (en) 2009-06-15 2015-11-18 National University of Singapore Influenza vaccine, composition, and methods of use
WO2013066272A1 (en) 2011-11-02 2013-05-10 National University Of Singapore Effect of an attenuated bordetella strain against allergic disease
EP2722338A1 (en) 2012-10-17 2014-04-23 INSERM (Institut National de la Santé et de la Recherche Médicale) Novel recombinant Bordetella strains
CN105722530B (zh) 2013-08-16 2020-06-02 罗切斯特大学 用于紧密连接屏障调节的设计肽
US9655959B2 (en) * 2014-10-01 2017-05-23 National University Of Singapore Adenylate cyclase deficient bordetella strains
CN114767718A (zh) * 2016-03-29 2022-07-22 里尔巴斯德研究所 突变型博德特氏菌属菌株及其使用方法
JP6598724B2 (ja) 2016-04-07 2019-10-30 株式会社ジェイテクト ステアリング装置
SG11202003333WA (en) 2017-10-18 2020-05-28 Pasteur Institut Bordetella strains expressing serotype 3 fimbriae
US20220249364A1 (en) 2019-06-05 2022-08-11 University Of Rochester Designed Inhibitors of Tight Junction Formation
EP4208472A1 (en) * 2020-09-04 2023-07-12 Intravacc B.V. Ompa mutations enhance omv production in bordetella pertussis
EP3909971A1 (en) 2020-09-28 2021-11-17 Institute of Life Sciences (ILS) Whole cell livestock vaccine for respiratory diseases

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4883761A (en) 1986-03-25 1989-11-28 The United States Of America As Represented By The Department Of Health And Human Services Pertussis toxin gene: cloning and expression of protective antigen
US5101019A (en) * 1987-05-22 1992-03-31 Takeda Chemical Industries, Ltd. Method for removing pertussis endotoxin, a pertussis toxoid and its production
US6713072B1 (en) 1987-11-02 2004-03-30 Chiron S.R.L. Immunologically active polypeptides with altered toxicity useful for the preparation of an antipertussis vaccine
GB9115332D0 (en) 1991-07-16 1991-08-28 Connaught Lab Manipulation of gene copy number in bordetella
FR2754543B1 (fr) 1996-10-11 1998-12-31 Pasteur Institut Souche de bordetella deficiente dans la production de toxine et exprimant une proteine hydride, liposomes comprenant de la fha et leurs utilisations comme vaccins, et utilisation de la fha pour stimuler les reponses immunitaires
FR2840319B1 (fr) * 2002-05-30 2004-08-20 Pasteur Institut Souches de bordetella rendues deficientes par attenuation genetique
EP1617805A4 (en) * 2003-04-11 2012-07-04 Medimmune Llc METHODS FOR PREVENTING OR TREATING RESPIRATORY CONDITIONS
GB0402131D0 (en) 2004-01-30 2004-03-03 Isis Innovation Delivery method
AU2007224734C1 (en) * 2006-03-10 2016-07-14 Institut National De La Sante Et De La Recherche Medicale (Inserm) Live attenuated Bordetella strains as a single dose vaccine against whooping cough
WO2008118592A2 (en) 2007-02-23 2008-10-02 The Penn State Research Foundation Use of an avirulent bordetella mutant as a live vaccine vector
CN100537767C (zh) * 2007-04-29 2009-09-09 中国药品生物制品检定所 百日咳疫苗保护性抗原的重组表达及其应用
US20120177688A1 (en) 2009-04-28 2012-07-12 Institut Pasteur De Lille Vaccine for Prophylaxis or Treatment of an Allergen-Driven Airway Pathology
CN101947323B (zh) * 2010-07-26 2013-02-27 北京绿竹生物制药有限公司 一种革兰氏阴性细菌疫苗及其制备方法
WO2013066272A1 (en) 2011-11-02 2013-05-10 National University Of Singapore Effect of an attenuated bordetella strain against allergic disease
EP2722338A1 (en) 2012-10-17 2014-04-23 INSERM (Institut National de la Santé et de la Recherche Médicale) Novel recombinant Bordetella strains
US9655959B2 (en) 2014-10-01 2017-05-23 National University Of Singapore Adenylate cyclase deficient bordetella strains
CN114767718A (zh) 2016-03-29 2022-07-22 里尔巴斯德研究所 突变型博德特氏菌属菌株及其使用方法
US10799573B2 (en) 2016-03-30 2020-10-13 Regents Of The University Of Minnesota Pertussis vaccines and methods of making and using
WO2018213361A1 (en) 2017-05-15 2018-11-22 Vanderbilt University LONG-CIRCULATING ZWITTERIONIC POLYPLEXES FOR siRNA DELIVERY
CA3070039A1 (en) 2017-07-18 2019-01-24 Serum Institute Of India Pvt Ltd. An immunogenic composition having improved stability, enhanced immunogenicity and reduced reactogenicity and process for preparation thereof
SG11202003333WA (en) 2017-10-18 2020-05-28 Pasteur Institut Bordetella strains expressing serotype 3 fimbriae
US12036405B2 (en) 2018-03-23 2024-07-16 The Board Of Regents Of The University Of Oklahoma System and method of electric-induced acoustic tomography for electrotherapy monitoring

Also Published As

Publication number Publication date
AU2010243708B2 (en) 2014-06-12
CN102448490B (zh) 2015-05-13
WO2010125014A1 (en) 2010-11-04
US20200282041A1 (en) 2020-09-10
EP3590532A1 (en) 2020-01-08
AU2010243708A1 (en) 2011-11-03
US8986709B2 (en) 2015-03-24
US10653765B2 (en) 2020-05-19
US9839683B2 (en) 2017-12-12
US11819545B2 (en) 2023-11-21
CA2759280C (en) 2016-09-20
EP2424564A1 (en) 2012-03-07
ES3024937T3 (en) 2025-06-05
EP2424564B1 (en) 2015-02-25
AU2010243708C1 (en) 2014-10-02
US20180085450A1 (en) 2018-03-29
US20120177688A1 (en) 2012-07-12
JP2012525346A (ja) 2012-10-22
EP3590532B1 (en) 2025-03-19
US20190358309A1 (en) 2019-11-28
US10420827B2 (en) 2019-09-24
CA2759280A1 (en) 2010-11-04
EP3590532C0 (en) 2025-03-19
JP5678034B2 (ja) 2015-02-25
ES2535412T3 (es) 2015-05-11
US20150182614A1 (en) 2015-07-02
US11110161B2 (en) 2021-09-07
CN102448490A (zh) 2012-05-09
SG175803A1 (en) 2011-12-29
US20210361759A1 (en) 2021-11-25
EP2910252A1 (en) 2015-08-26
US20130183336A1 (en) 2013-07-18

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