CA2759280C - Vaccine for prophylaxis or treatment of an allergen-driven airway pathology - Google Patents
Vaccine for prophylaxis or treatment of an allergen-driven airway pathology Download PDFInfo
- Publication number
- CA2759280C CA2759280C CA2759280A CA2759280A CA2759280C CA 2759280 C CA2759280 C CA 2759280C CA 2759280 A CA2759280 A CA 2759280A CA 2759280 A CA2759280 A CA 2759280A CA 2759280 C CA2759280 C CA 2759280C
- Authority
- CA
- Canada
- Prior art keywords
- bordetella pertussis
- live attenuated
- attenuated bordetella
- strain
- allergen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/099—Bordetella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/544—Mucosal route to the airways
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09305371 | 2009-04-28 | ||
| EP09305371.8 | 2009-04-28 | ||
| PCT/EP2010/055507 WO2010125014A1 (en) | 2009-04-28 | 2010-04-26 | Vaccine for prophylaxis or treatment of an allergen-driven airway pathology |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2759280A1 CA2759280A1 (en) | 2010-11-04 |
| CA2759280C true CA2759280C (en) | 2016-09-20 |
Family
ID=41057387
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2759280A Active CA2759280C (en) | 2009-04-28 | 2010-04-26 | Vaccine for prophylaxis or treatment of an allergen-driven airway pathology |
Country Status (10)
| Country | Link |
|---|---|
| US (7) | US20120177688A1 (enExample) |
| EP (3) | EP3590532B1 (enExample) |
| JP (1) | JP5678034B2 (enExample) |
| CN (1) | CN102448490B (enExample) |
| AU (1) | AU2010243708C1 (enExample) |
| CA (1) | CA2759280C (enExample) |
| DK (1) | DK2424564T3 (enExample) |
| ES (2) | ES2535412T3 (enExample) |
| SG (1) | SG175803A1 (enExample) |
| WO (1) | WO2010125014A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9119804B2 (en) | 2006-03-10 | 2015-09-01 | Institut Pasteur De Lille | Live attenuated bordetella strains as a single dose vaccine against whooping cough |
| SG175803A1 (en) | 2009-04-28 | 2011-12-29 | Pasteur Institut | Vaccine for prophylaxis or treatment of an allergen-driven airway pathology |
| DK2442826T3 (en) | 2009-06-15 | 2015-09-21 | Univ Singapore | Influenza vaccine, composition and methods of using |
| DK2773371T3 (da) * | 2011-11-02 | 2020-03-09 | Nat Univ Singapore | Virkning af en svækket bordetella-stamme mod allergisk sygdom |
| EP2722338A1 (en) | 2012-10-17 | 2014-04-23 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Novel recombinant Bordetella strains |
| WO2015024022A2 (en) | 2013-08-16 | 2015-02-19 | University Of Rochester | Designed peptides for tight junction barrier modulation |
| US9655959B2 (en) * | 2014-10-01 | 2017-05-23 | National University Of Singapore | Adenylate cyclase deficient bordetella strains |
| EP4541809A3 (en) * | 2016-03-29 | 2025-06-25 | Institut Pasteur de Lille | Mutant bordetella strains and methods of use |
| JP6598724B2 (ja) | 2016-04-07 | 2019-10-30 | 株式会社ジェイテクト | ステアリング装置 |
| SG11202003333WA (en) | 2017-10-18 | 2020-05-28 | Pasteur Institut | Bordetella strains expressing serotype 3 fimbriae |
| US20220249364A1 (en) | 2019-06-05 | 2022-08-11 | University Of Rochester | Designed Inhibitors of Tight Junction Formation |
| US20250263447A1 (en) * | 2020-09-04 | 2025-08-21 | Intravacc B.V. | Ompa mutations enhance omv production in bordetella pertussis |
| EP3909971A1 (en) | 2020-09-28 | 2021-11-17 | Institute of Life Sciences (ILS) | Whole cell livestock vaccine for respiratory diseases |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4883761A (en) | 1986-03-25 | 1989-11-28 | The United States Of America As Represented By The Department Of Health And Human Services | Pertussis toxin gene: cloning and expression of protective antigen |
| US5101019A (en) * | 1987-05-22 | 1992-03-31 | Takeda Chemical Industries, Ltd. | Method for removing pertussis endotoxin, a pertussis toxoid and its production |
| US6713072B1 (en) | 1987-11-02 | 2004-03-30 | Chiron S.R.L. | Immunologically active polypeptides with altered toxicity useful for the preparation of an antipertussis vaccine |
| GB9115332D0 (en) | 1991-07-16 | 1991-08-28 | Connaught Lab | Manipulation of gene copy number in bordetella |
| FR2754543B1 (fr) | 1996-10-11 | 1998-12-31 | Pasteur Institut | Souche de bordetella deficiente dans la production de toxine et exprimant une proteine hydride, liposomes comprenant de la fha et leurs utilisations comme vaccins, et utilisation de la fha pour stimuler les reponses immunitaires |
| FR2840319B1 (fr) * | 2002-05-30 | 2004-08-20 | Pasteur Institut | Souches de bordetella rendues deficientes par attenuation genetique |
| EP1617805A4 (en) * | 2003-04-11 | 2012-07-04 | Medimmune Llc | METHODS FOR PREVENTING OR TREATING RESPIRATORY CONDITIONS |
| GB0402131D0 (en) | 2004-01-30 | 2004-03-03 | Isis Innovation | Delivery method |
| US9119804B2 (en) | 2006-03-10 | 2015-09-01 | Institut Pasteur De Lille | Live attenuated bordetella strains as a single dose vaccine against whooping cough |
| EP2134359A4 (en) | 2007-02-23 | 2010-06-16 | Penn State Res Found | USE OF A NONVIRULENT BORDETELLA MUTANT AS LIVING VACCINE VECTOR |
| CN100537767C (zh) * | 2007-04-29 | 2009-09-09 | 中国药品生物制品检定所 | 百日咳疫苗保护性抗原的重组表达及其应用 |
| SG175803A1 (en) | 2009-04-28 | 2011-12-29 | Pasteur Institut | Vaccine for prophylaxis or treatment of an allergen-driven airway pathology |
| CN101947323B (zh) * | 2010-07-26 | 2013-02-27 | 北京绿竹生物制药有限公司 | 一种革兰氏阴性细菌疫苗及其制备方法 |
| DK2773371T3 (da) | 2011-11-02 | 2020-03-09 | Nat Univ Singapore | Virkning af en svækket bordetella-stamme mod allergisk sygdom |
| EP2722338A1 (en) | 2012-10-17 | 2014-04-23 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Novel recombinant Bordetella strains |
| US9655959B2 (en) | 2014-10-01 | 2017-05-23 | National University Of Singapore | Adenylate cyclase deficient bordetella strains |
| EP4541809A3 (en) | 2016-03-29 | 2025-06-25 | Institut Pasteur de Lille | Mutant bordetella strains and methods of use |
| US10799573B2 (en) | 2016-03-30 | 2020-10-13 | Regents Of The University Of Minnesota | Pertussis vaccines and methods of making and using |
| US20200171169A1 (en) | 2017-05-15 | 2020-06-04 | Vanderbilt University | LONG-CIRCULATING ZWITTERIONIC POLYPLEXES FOR siRNA DELIVERY |
| CN111032078A (zh) | 2017-07-18 | 2020-04-17 | 血清研究所印度私人有限公司 | 具有改善的稳定性、增强的免疫原性和降低的反应原性的免疫原性组合物及其制备方法 |
| SG11202003333WA (en) | 2017-10-18 | 2020-05-28 | Pasteur Institut | Bordetella strains expressing serotype 3 fimbriae |
| US12036405B2 (en) | 2018-03-23 | 2024-07-16 | The Board Of Regents Of The University Of Oklahoma | System and method of electric-induced acoustic tomography for electrotherapy monitoring |
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| US11110161B2 (en) | 2021-09-07 |
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| EP3590532B1 (en) | 2025-03-19 |
| US20210361759A1 (en) | 2021-11-25 |
| WO2010125014A1 (en) | 2010-11-04 |
| EP2910252A1 (en) | 2015-08-26 |
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| US11819545B2 (en) | 2023-11-21 |
| EP3590532C0 (en) | 2025-03-19 |
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| EP2424564A1 (en) | 2012-03-07 |
| SG175803A1 (en) | 2011-12-29 |
| US10420827B2 (en) | 2019-09-24 |
| US9839683B2 (en) | 2017-12-12 |
| ES3024937T3 (en) | 2025-06-05 |
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