JP2012525346A5 - - Google Patents
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- Publication number
- JP2012525346A5 JP2012525346A5 JP2012507703A JP2012507703A JP2012525346A5 JP 2012525346 A5 JP2012525346 A5 JP 2012525346A5 JP 2012507703 A JP2012507703 A JP 2012507703A JP 2012507703 A JP2012507703 A JP 2012507703A JP 2012525346 A5 JP2012525346 A5 JP 2012525346A5
- Authority
- JP
- Japan
- Prior art keywords
- bordetella pertussis
- live
- vaccine according
- attenuated bordetella
- pertussis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000588832 Bordetella pertussis Species 0.000 claims 6
- 230000002238 attenuated effect Effects 0.000 claims 6
- 229940066827 pertussis vaccine Drugs 0.000 claims 3
- 229960005486 vaccine Drugs 0.000 claims 3
- APUIQTDTBPKWKE-RNPGEKFLSA-N (2r,6s)-6-[[(4r)-4-[[(2s)-2-[2-[[(1r,2s,3r,4r,5r)-4-acetamido-2-[(2s,3r,4r,5s,6r)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6,8-dioxabicyclo[3.2.1]octan-3-yl]oxy]propanoylamino]propanoyl]amino]-4-carboxybutanoyl]amino]-2-amino-7-[[(2r)-2-am Chemical compound O([C@@H]1[C@H]2CO[C@H](O2)[C@H](NC(C)=O)[C@H]1OC(C)C(=O)N[C@@H](C)C(=O)N[C@H](CCC(=O)N[C@@H](CCC[C@@H](N)C(O)=O)C(=O)NC(=O)[C@H](N)C)C(O)=O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1NC(C)=O APUIQTDTBPKWKE-RNPGEKFLSA-N 0.000 claims 2
- 108010081690 Pertussis Toxin Proteins 0.000 claims 2
- 208000035285 Allergic Seasonal Rhinitis Diseases 0.000 claims 1
- 241000588807 Bordetella Species 0.000 claims 1
- 208000029523 Interstitial Lung disease Diseases 0.000 claims 1
- 206010040893 Skin necrosis Diseases 0.000 claims 1
- 239000013566 allergen Substances 0.000 claims 1
- 230000002009 allergenic effect Effects 0.000 claims 1
- 201000009961 allergic asthma Diseases 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 208000006673 asthma Diseases 0.000 claims 1
- 230000007170 pathology Effects 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 239000003053 toxin Substances 0.000 claims 1
- 231100000765 toxin Toxicity 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09305371 | 2009-04-28 | ||
| EP09305371.8 | 2009-04-28 | ||
| PCT/EP2010/055507 WO2010125014A1 (en) | 2009-04-28 | 2010-04-26 | Vaccine for prophylaxis or treatment of an allergen-driven airway pathology |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012525346A JP2012525346A (ja) | 2012-10-22 |
| JP2012525346A5 true JP2012525346A5 (enExample) | 2013-05-02 |
| JP5678034B2 JP5678034B2 (ja) | 2015-02-25 |
Family
ID=41057387
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012507703A Active JP5678034B2 (ja) | 2009-04-28 | 2010-04-26 | アレルゲン駆動性気道病態の予防または治療のためのワクチン |
Country Status (10)
| Country | Link |
|---|---|
| US (7) | US20120177688A1 (enExample) |
| EP (3) | EP2424564B1 (enExample) |
| JP (1) | JP5678034B2 (enExample) |
| CN (1) | CN102448490B (enExample) |
| AU (1) | AU2010243708C1 (enExample) |
| CA (1) | CA2759280C (enExample) |
| DK (1) | DK2424564T3 (enExample) |
| ES (2) | ES3024937T3 (enExample) |
| SG (1) | SG175803A1 (enExample) |
| WO (1) | WO2010125014A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2007224734C1 (en) | 2006-03-10 | 2016-07-14 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Live attenuated Bordetella strains as a single dose vaccine against whooping cough |
| US20120177688A1 (en) | 2009-04-28 | 2012-07-12 | Institut Pasteur De Lille | Vaccine for Prophylaxis or Treatment of an Allergen-Driven Airway Pathology |
| EP2944320A1 (en) | 2009-06-15 | 2015-11-18 | National University of Singapore | Influenza vaccine, composition, and methods of use |
| WO2013066272A1 (en) | 2011-11-02 | 2013-05-10 | National University Of Singapore | Effect of an attenuated bordetella strain against allergic disease |
| EP2722338A1 (en) | 2012-10-17 | 2014-04-23 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Novel recombinant Bordetella strains |
| CN105722530B (zh) | 2013-08-16 | 2020-06-02 | 罗切斯特大学 | 用于紧密连接屏障调节的设计肽 |
| US9655959B2 (en) * | 2014-10-01 | 2017-05-23 | National University Of Singapore | Adenylate cyclase deficient bordetella strains |
| CN114767718A (zh) * | 2016-03-29 | 2022-07-22 | 里尔巴斯德研究所 | 突变型博德特氏菌属菌株及其使用方法 |
| JP6598724B2 (ja) | 2016-04-07 | 2019-10-30 | 株式会社ジェイテクト | ステアリング装置 |
| SG11202003333WA (en) | 2017-10-18 | 2020-05-28 | Pasteur Institut | Bordetella strains expressing serotype 3 fimbriae |
| US20220249364A1 (en) | 2019-06-05 | 2022-08-11 | University Of Rochester | Designed Inhibitors of Tight Junction Formation |
| EP4208472A1 (en) * | 2020-09-04 | 2023-07-12 | Intravacc B.V. | Ompa mutations enhance omv production in bordetella pertussis |
| EP3909971A1 (en) | 2020-09-28 | 2021-11-17 | Institute of Life Sciences (ILS) | Whole cell livestock vaccine for respiratory diseases |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4883761A (en) | 1986-03-25 | 1989-11-28 | The United States Of America As Represented By The Department Of Health And Human Services | Pertussis toxin gene: cloning and expression of protective antigen |
| US5101019A (en) * | 1987-05-22 | 1992-03-31 | Takeda Chemical Industries, Ltd. | Method for removing pertussis endotoxin, a pertussis toxoid and its production |
| US6713072B1 (en) | 1987-11-02 | 2004-03-30 | Chiron S.R.L. | Immunologically active polypeptides with altered toxicity useful for the preparation of an antipertussis vaccine |
| GB9115332D0 (en) | 1991-07-16 | 1991-08-28 | Connaught Lab | Manipulation of gene copy number in bordetella |
| FR2754543B1 (fr) | 1996-10-11 | 1998-12-31 | Pasteur Institut | Souche de bordetella deficiente dans la production de toxine et exprimant une proteine hydride, liposomes comprenant de la fha et leurs utilisations comme vaccins, et utilisation de la fha pour stimuler les reponses immunitaires |
| FR2840319B1 (fr) * | 2002-05-30 | 2004-08-20 | Pasteur Institut | Souches de bordetella rendues deficientes par attenuation genetique |
| EP1617805A4 (en) * | 2003-04-11 | 2012-07-04 | Medimmune Llc | METHODS FOR PREVENTING OR TREATING RESPIRATORY CONDITIONS |
| GB0402131D0 (en) | 2004-01-30 | 2004-03-03 | Isis Innovation | Delivery method |
| AU2007224734C1 (en) * | 2006-03-10 | 2016-07-14 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Live attenuated Bordetella strains as a single dose vaccine against whooping cough |
| WO2008118592A2 (en) | 2007-02-23 | 2008-10-02 | The Penn State Research Foundation | Use of an avirulent bordetella mutant as a live vaccine vector |
| CN100537767C (zh) * | 2007-04-29 | 2009-09-09 | 中国药品生物制品检定所 | 百日咳疫苗保护性抗原的重组表达及其应用 |
| US20120177688A1 (en) | 2009-04-28 | 2012-07-12 | Institut Pasteur De Lille | Vaccine for Prophylaxis or Treatment of an Allergen-Driven Airway Pathology |
| CN101947323B (zh) * | 2010-07-26 | 2013-02-27 | 北京绿竹生物制药有限公司 | 一种革兰氏阴性细菌疫苗及其制备方法 |
| WO2013066272A1 (en) | 2011-11-02 | 2013-05-10 | National University Of Singapore | Effect of an attenuated bordetella strain against allergic disease |
| EP2722338A1 (en) | 2012-10-17 | 2014-04-23 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Novel recombinant Bordetella strains |
| US9655959B2 (en) | 2014-10-01 | 2017-05-23 | National University Of Singapore | Adenylate cyclase deficient bordetella strains |
| CN114767718A (zh) | 2016-03-29 | 2022-07-22 | 里尔巴斯德研究所 | 突变型博德特氏菌属菌株及其使用方法 |
| US10799573B2 (en) | 2016-03-30 | 2020-10-13 | Regents Of The University Of Minnesota | Pertussis vaccines and methods of making and using |
| WO2018213361A1 (en) | 2017-05-15 | 2018-11-22 | Vanderbilt University | LONG-CIRCULATING ZWITTERIONIC POLYPLEXES FOR siRNA DELIVERY |
| CA3070039A1 (en) | 2017-07-18 | 2019-01-24 | Serum Institute Of India Pvt Ltd. | An immunogenic composition having improved stability, enhanced immunogenicity and reduced reactogenicity and process for preparation thereof |
| SG11202003333WA (en) | 2017-10-18 | 2020-05-28 | Pasteur Institut | Bordetella strains expressing serotype 3 fimbriae |
| US12036405B2 (en) | 2018-03-23 | 2024-07-16 | The Board Of Regents Of The University Of Oklahoma | System and method of electric-induced acoustic tomography for electrotherapy monitoring |
-
2010
- 2010-04-26 US US13/266,561 patent/US20120177688A1/en not_active Abandoned
- 2010-04-26 ES ES19176782T patent/ES3024937T3/es active Active
- 2010-04-26 CA CA2759280A patent/CA2759280C/en active Active
- 2010-04-26 WO PCT/EP2010/055507 patent/WO2010125014A1/en not_active Ceased
- 2010-04-26 CN CN201080019636.0A patent/CN102448490B/zh active Active
- 2010-04-26 ES ES10715245.6T patent/ES2535412T3/es active Active
- 2010-04-26 EP EP10715245.6A patent/EP2424564B1/en active Active
- 2010-04-26 EP EP19176782.1A patent/EP3590532B1/en active Active
- 2010-04-26 DK DK10715245T patent/DK2424564T3/en active
- 2010-04-26 JP JP2012507703A patent/JP5678034B2/ja active Active
- 2010-04-26 SG SG2011078771A patent/SG175803A1/en unknown
- 2010-04-26 EP EP15154206.5A patent/EP2910252A1/en not_active Ceased
- 2010-04-26 AU AU2010243708A patent/AU2010243708C1/en active Active
-
2013
- 2013-03-01 US US13/782,754 patent/US8986709B2/en active Active
-
2015
- 2015-01-30 US US14/609,461 patent/US9839683B2/en active Active
-
2017
- 2017-11-01 US US15/800,921 patent/US10420827B2/en active Active
-
2019
- 2019-08-09 US US16/537,342 patent/US10653765B2/en active Active
-
2020
- 2020-04-03 US US16/840,276 patent/US11110161B2/en active Active
-
2021
- 2021-08-02 US US17/392,066 patent/US11819545B2/en active Active
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