JP5656192B2 - ソフトマテリアルのマイクロアレイ作製方法 - Google Patents

ソフトマテリアルのマイクロアレイ作製方法 Download PDF

Info

Publication number
JP5656192B2
JP5656192B2 JP2011070934A JP2011070934A JP5656192B2 JP 5656192 B2 JP5656192 B2 JP 5656192B2 JP 2011070934 A JP2011070934 A JP 2011070934A JP 2011070934 A JP2011070934 A JP 2011070934A JP 5656192 B2 JP5656192 B2 JP 5656192B2
Authority
JP
Japan
Prior art keywords
microarray
soft material
substrate
soft
layer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2011070934A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012202968A5 (enExample
JP2012202968A (ja
Inventor
檜山 聡
聡 檜山
香織 栗林
香織 栗林
弘晃 尾上
弘晃 尾上
昌治 竹内
昌治 竹内
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NTT Docomo Inc
University of Tokyo NUC
Original Assignee
NTT Docomo Inc
University of Tokyo NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NTT Docomo Inc, University of Tokyo NUC filed Critical NTT Docomo Inc
Priority to JP2011070934A priority Critical patent/JP5656192B2/ja
Priority to PCT/JP2012/057996 priority patent/WO2012133450A1/ja
Priority to US13/814,588 priority patent/US8999443B2/en
Priority to CN201280003445.4A priority patent/CN103180735B/zh
Priority to EP12763427.7A priority patent/EP2594941B1/en
Publication of JP2012202968A publication Critical patent/JP2012202968A/ja
Publication of JP2012202968A5 publication Critical patent/JP2012202968A5/ja
Application granted granted Critical
Publication of JP5656192B2 publication Critical patent/JP5656192B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B81MICROSTRUCTURAL TECHNOLOGY
    • B81CPROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C1/00Manufacture or treatment of devices or systems in or on a substrate
    • B81C1/00015Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems
    • B81C1/00206Processes for functionalising a surface, e.g. provide the surface with specific mechanical, chemical or biological properties
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05DPROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D1/00Processes for applying liquids or other fluent materials
    • B05D1/32Processes for applying liquids or other fluent materials using means for protecting parts of a surface not to be coated, e.g. using stencils, resists
    • B05D1/322Removable films used as masks
    • B05D1/325Masking layer made of peelable film
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N37/00Details not covered by any other group of this subclass
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00279Features relating to reactor vessels
    • B01J2219/00306Reactor vessels in a multiple arrangement
    • B01J2219/00313Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B01J2219/00315Microtiter plates
    • B01J2219/00317Microwell devices, i.e. having large numbers of wells
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • B01J2219/00527Sheets
    • B01J2219/00529DNA chips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00605Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00632Introduction of reactive groups to the surface
    • B01J2219/00637Introduction of reactive groups to the surface by coating it with another layer
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00659Two-dimensional arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/0072Organic compounds
    • B01J2219/00722Nucleotides
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/0072Organic compounds
    • B01J2219/00725Peptides
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B81MICROSTRUCTURAL TECHNOLOGY
    • B81BMICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B2201/00Specific applications of microelectromechanical systems
    • B81B2201/02Sensors
    • B81B2201/0214Biosensors; Chemical sensors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B81MICROSTRUCTURAL TECHNOLOGY
    • B81BMICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B2201/00Specific applications of microelectromechanical systems
    • B81B2201/05Microfluidics
    • B81B2201/058Microfluidics not provided for in B81B2201/051 - B81B2201/054

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Manufacturing & Machinery (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Plant Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2011070934A 2011-03-28 2011-03-28 ソフトマテリアルのマイクロアレイ作製方法 Expired - Fee Related JP5656192B2 (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2011070934A JP5656192B2 (ja) 2011-03-28 2011-03-28 ソフトマテリアルのマイクロアレイ作製方法
PCT/JP2012/057996 WO2012133450A1 (ja) 2011-03-28 2012-03-27 ソフトマテリアルのマイクロアレイ作製方法
US13/814,588 US8999443B2 (en) 2011-03-28 2012-03-27 Method for fabricating a microarray of soft materials
CN201280003445.4A CN103180735B (zh) 2011-03-28 2012-03-27 软物质的微阵列制作方法
EP12763427.7A EP2594941B1 (en) 2011-03-28 2012-03-27 Method for fabricating microarrays of soft materials

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2011070934A JP5656192B2 (ja) 2011-03-28 2011-03-28 ソフトマテリアルのマイクロアレイ作製方法

Publications (3)

Publication Number Publication Date
JP2012202968A JP2012202968A (ja) 2012-10-22
JP2012202968A5 JP2012202968A5 (enExample) 2012-11-29
JP5656192B2 true JP5656192B2 (ja) 2015-01-21

Family

ID=46931164

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011070934A Expired - Fee Related JP5656192B2 (ja) 2011-03-28 2011-03-28 ソフトマテリアルのマイクロアレイ作製方法

Country Status (5)

Country Link
US (1) US8999443B2 (enExample)
EP (1) EP2594941B1 (enExample)
JP (1) JP5656192B2 (enExample)
CN (1) CN103180735B (enExample)
WO (1) WO2012133450A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3305721B1 (en) 2015-06-08 2023-10-18 Japan Science And Technology Agency High-density micro-chamber array and measurement method using same
US9561953B1 (en) * 2015-08-24 2017-02-07 Infineon Technologies Ag Method of forming a protective coating for a packaged semiconductor device
JP7082364B2 (ja) * 2018-03-02 2022-06-08 日本電信電話株式会社 フィルム状ソフトマテリアル、蛍光フィルム基材及びフィルム状ソフトマテリアルの製造方法、並びに応力計測方法
DE102020115368B4 (de) 2019-10-29 2025-05-22 Taiwan Semiconductor Manufacturing Co., Ltd. Herstellungsverfahren für eine halbleitervorrichtung
JP2021150493A (ja) * 2020-03-19 2021-09-27 キオクシア株式会社 半導体記憶装置
CN113213419B (zh) * 2020-07-15 2023-12-08 江苏力博医药生物技术股份有限公司 一种微阵列结构图案化的工艺

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6559474B1 (en) * 2000-09-18 2003-05-06 Cornell Research Foundation, Inc, Method for topographical patterning of materials
JP4007269B2 (ja) * 2003-07-29 2007-11-14 オムロン株式会社 生体分子の形状転写方法、チップ基板の製造方法及びバイオチップの製造方法
JP2006114489A (ja) 2004-09-14 2006-04-27 Nagoya Institute Of Technology 誘電体メタマテリアル、および磁性体メタマテリアル
JP2008014352A (ja) 2006-07-04 2008-01-24 Maezawa Kyuso Industries Co Ltd 逆止弁ユニットと濾過整流板
WO2008097360A2 (en) * 2006-09-14 2008-08-14 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Polymeric nanopillars and nanotubes, their manufacture and uses
CN103443624A (zh) * 2007-03-26 2013-12-11 纳米系统公司 形成受控单分子层的方法和装置

Also Published As

Publication number Publication date
CN103180735A (zh) 2013-06-26
CN103180735B (zh) 2014-12-31
EP2594941B1 (en) 2015-10-07
JP2012202968A (ja) 2012-10-22
WO2012133450A1 (ja) 2012-10-04
US8999443B2 (en) 2015-04-07
US20130136863A1 (en) 2013-05-30
EP2594941A1 (en) 2013-05-22
EP2594941A4 (en) 2014-08-13

Similar Documents

Publication Publication Date Title
JP5656192B2 (ja) ソフトマテリアルのマイクロアレイ作製方法
US11278859B2 (en) Patterning device
Romanov et al. A critical comparison of protein microarray fabrication technologies
ES2848062T3 (es) Sustratos estructurados para mejorar la detección de emisiones de luz y métodos relacionados con los mismos
Bog et al. Large-scale parallel surface functionalization of goblet-type whispering gallery mode microcavity arrays for biosensing applications
Kim et al. Fracture-based micro-and nanofabrication for biological applications
JP2010531972A (ja) 制御された単分子層形成のための方法及びデバイス
JP6579465B2 (ja) マイクロウェルプレート、マイクロウェル装置、細胞解析方法及びマイクロウェルプレートの製造方法
CN112543678B (zh) 图案化微流体装置及其制造方法
EP1733229B1 (en) Patterning method for biosensor applications and devices comprising such patterns
US20100112342A1 (en) Substrate for biochip and method of manufacturing the substrate
JP2013044604A (ja) 金属酸化物の絶縁膜を用いたバイオチップ
Han et al. 3D artificial cell membranes as versatile platforms for biological applications
KR20240042871A (ko) 딥러닝 및 자기조립단층막 기반 알츠하이머병 진단 방법 및 이를 위한 sers 기판
CN111254061B (zh) 一种探针分子印刷芯片及其制造方法
Han et al. Lipid bilayer membrane arrays: fabrication and applications
US20060263832A1 (en) Patterning of centrosomes and centrosome fragments as templates for directed growth of microtubules
JP2005245331A (ja) 薄膜形成用デバイス、薄膜デバイス及びその製造方法
Sahin et al. Rapid Turnaround Fabrication of Peptide Nucleic Acid (PNA)-Immobilized Nanowire Biosensors by O 2-Plasma Assisted Lithography of e-Beam Resists
Hiyama et al. Biomolecular motor-based cargo transporters with loading/unloading mechanisms on a micro-patterned DNA array
US9663809B2 (en) Method for producing RNA membrane and RNA membrane produced thereby
ES3042733T3 (en) Micro-nanofluidic chip, preparation method therefor and use thereof
JP2008134188A (ja) プローブ固相化反応アレイおよび該アレイの製造方法
JP6143282B2 (ja) 核酸の伸長・固定デバイス、該デバイスを用いた核酸の伸長・固定方法、核酸固定部材、及び核酸の伸長・固定デバイスを用いて作製した核酸標本
KR101337504B1 (ko) 바이오 칩 및 그의 제조 방법

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120802

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20120802

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20120802

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20130903

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20131028

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20140408

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140609

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20141111

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20141118

R150 Certificate of patent or registration of utility model

Ref document number: 5656192

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees