JP5649455B2 - ナノ粒子を含む移植可能な製品 - Google Patents

ナノ粒子を含む移植可能な製品 Download PDF

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Publication number
JP5649455B2
JP5649455B2 JP2010546211A JP2010546211A JP5649455B2 JP 5649455 B2 JP5649455 B2 JP 5649455B2 JP 2010546211 A JP2010546211 A JP 2010546211A JP 2010546211 A JP2010546211 A JP 2010546211A JP 5649455 B2 JP5649455 B2 JP 5649455B2
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cancer
medical product
tumor
acid
medical
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JP2011511684A (ja
JP2011511684A5 (cg-RX-API-DMAC7.html
Inventor
ブルクハルト ティーセン
ブルクハルト ティーセン
アンドレアス ヨルダン
アンドレアス ヨルダン
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Magforce AG
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Magforce AG
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0028—Disruption, e.g. by heat or ultrasounds, sonophysical or sonochemical activation, e.g. thermosensitive or heat-sensitive liposomes, disruption of calculi with a medicinal preparation and ultrasounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/446—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with other specific inorganic fillers other than those covered by A61L27/443 or A61L27/46
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0052—Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A61L2300/604—Biodegradation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/80—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Materials Engineering (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Composite Materials (AREA)
  • Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)
JP2010546211A 2008-02-11 2009-02-11 ナノ粒子を含む移植可能な製品 Active JP5649455B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE102008008522A DE102008008522A1 (de) 2008-02-11 2008-02-11 Implantierbare Nanopartikel-enthaltende Produkte
DE102008008522.7 2008-02-11
US7108408P 2008-04-11 2008-04-11
US61/071,084 2008-04-11
PCT/DE2009/000196 WO2009100716A2 (de) 2008-02-11 2009-02-11 Implantierbare nanopartikel-enthaltende produkte

Publications (3)

Publication Number Publication Date
JP2011511684A JP2011511684A (ja) 2011-04-14
JP2011511684A5 JP2011511684A5 (cg-RX-API-DMAC7.html) 2013-04-11
JP5649455B2 true JP5649455B2 (ja) 2015-01-07

Family

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JP2010546211A Active JP5649455B2 (ja) 2008-02-11 2009-02-11 ナノ粒子を含む移植可能な製品

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Country Link
US (1) US20110223255A1 (cg-RX-API-DMAC7.html)
EP (1) EP2249804B1 (cg-RX-API-DMAC7.html)
JP (1) JP5649455B2 (cg-RX-API-DMAC7.html)
KR (1) KR101581973B1 (cg-RX-API-DMAC7.html)
CN (1) CN101938993A (cg-RX-API-DMAC7.html)
AU (1) AU2009214533B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0906611A8 (cg-RX-API-DMAC7.html)
CA (1) CA2712832C (cg-RX-API-DMAC7.html)
DE (2) DE102008008522A1 (cg-RX-API-DMAC7.html)
DK (1) DK2249804T3 (cg-RX-API-DMAC7.html)
ES (1) ES2619509T3 (cg-RX-API-DMAC7.html)
IL (1) IL207137A (cg-RX-API-DMAC7.html)
MX (1) MX2010008806A (cg-RX-API-DMAC7.html)
PL (1) PL2249804T3 (cg-RX-API-DMAC7.html)
PT (1) PT2249804T (cg-RX-API-DMAC7.html)
RU (1) RU2524644C2 (cg-RX-API-DMAC7.html)
SG (1) SG188146A1 (cg-RX-API-DMAC7.html)
WO (1) WO2009100716A2 (cg-RX-API-DMAC7.html)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2347775T3 (da) 2005-12-13 2020-07-13 Harvard College Skabeloner til celletransplantation
US10328133B2 (en) 2008-02-13 2019-06-25 President And Fellows Of Harvard College Continuous cell programming devices
JP5529023B2 (ja) * 2008-09-04 2014-06-25 猛 小林 抗制御性ｔ細胞抗体と磁性微粒子を含む悪性腫瘍の温熱治療用キット、及びその温熱治療法
JP5463531B2 (ja) * 2009-07-22 2014-04-09 国立大学法人 東京大学 Ｐｈｄ２発現抑制物質搭載ポリイオンコンプレックス
JP5926180B2 (ja) 2009-07-31 2016-05-25 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 寛容原性療法のための細胞のプログラミングの方法
ES2600229T3 (es) * 2009-11-12 2017-02-07 Helmholtz-Zentrum Geesthacht Zentrum für Material- und Küstenforschung GmbH Nanopartículas magnéticas biocompatibles para el tratamiento de glioblastomas
DE102009058769A1 (de) * 2009-12-16 2011-06-22 MagForce Nanotechnologies AG, 10589 Temperaturabhängige Aktivierung von katalytischen Nukleinsäuren zur kontrollierten Wirkstofffreisetzung
WO2012001577A1 (en) * 2010-06-29 2012-01-05 Koninklijke Philips Electronics N.V. Synthesis and use of iron oleate
US9572880B2 (en) 2010-08-27 2017-02-21 Sienna Biopharmaceuticals, Inc. Ultrasound delivery of nanoparticles
CN107441628B (zh) 2010-08-27 2020-06-19 斯巴卡有限公司 用于靶向热调节的组合物和方法
EP2624873B1 (en) 2010-10-06 2019-12-04 President and Fellows of Harvard College Injectable, pore-forming hydrogels for materials-based cell therapies
US8944067B2 (en) * 2010-12-15 2015-02-03 Kci Licensing, Inc. Targeted delivery of magnetically tagged active agents in combination with negative pressure wound therapy
US9764157B2 (en) 2011-01-17 2017-09-19 University Of Utah Research Foundation Methods, systems, and apparatus for reducing the frequency and/or severity of photophobic responses or for modulating circadian cycles
US10359552B2 (en) 2011-01-17 2019-07-23 University Of Utah Research Foundation Methods, systems, and apparatus for reducing the frequency and/or severity of photophobic responses or for modulating circadian cycles
EP4245347A3 (en) 2011-01-17 2023-12-06 University of Utah Research Foundation Apparatus and methods for reducing frequency or severity of photophobic responses or modulating circadian cycles
PL2683440T3 (pl) 2011-03-10 2016-05-31 Magforce Ag Wspomagane komputerowo narzędzie symulacyjne do pomocy w planowaniu termoterapii
US9675561B2 (en) 2011-04-28 2017-06-13 President And Fellows Of Harvard College Injectable cryogel vaccine devices and methods of use thereof
ES2685327T3 (es) 2011-04-28 2018-10-08 President And Fellows Of Harvard College Armazones tridimensionales macroscópicos preformados inyectables para administración mínimamente invasiva
EP2704666A4 (en) * 2011-05-06 2014-12-17 Mitchel J Doktycz ACTIVE SUBSTANCES TO PREVENT AND PREVENT POLLUTION OF SURFACES
EP2714073B1 (en) 2011-06-03 2021-03-10 President and Fellows of Harvard College In situ antigen-generating cancer vaccine
CN102379762B (zh) * 2011-08-02 2015-03-25 上海微创医疗器械（集团）有限公司 一种带凹槽的生物可降解支架及其制备方法
AU2012292554B2 (en) * 2011-08-10 2014-10-30 Magforce Ag Agglomerating magnetic alkoxysilane-coated nanoparticles
US10945965B2 (en) 2011-12-16 2021-03-16 Nanobiotix Nanoparticles comprising metallic and hafnium oxide materials, preparation and uses thereof
LT2838515T (lt) 2012-04-16 2020-03-10 President And Fellows Of Harvard College Mezoporinės silico dioksido kompozicijos, skirtos imuninio atsako moduliavimui
PL2906286T3 (pl) 2012-10-11 2018-03-30 Nanocomposix, Inc. Kompozycje zawierające nanopłytki srebra i sposoby ich przygotowywania
US10406228B2 (en) * 2012-11-29 2019-09-10 The Johns Hopkins University Process for making iron oxide nanoparticle preparations for cancer hyperthermia
US20140219926A1 (en) * 2013-02-01 2014-08-07 The Trustees Of Dartmouth College Biodegradable Iron Oxide Nanoparticle Gel for Tumor Bed Therapy
WO2014124329A1 (en) 2013-02-08 2014-08-14 University Of Louisville Research Foundation, Inc. Nanoparticles for drug delivery
CN103203903A (zh) * 2013-03-25 2013-07-17 海龙核材科技（江苏）有限公司 一种电场磁场下响应的传感材料及其制备方法
WO2014195374A1 (en) * 2013-06-04 2014-12-11 Fumedica Ag Cytotoxic substance for use in combination with radiotherapy in cancer treatment
BR112015031977A2 (pt) * 2013-06-20 2017-07-25 Nanobiotix gel biocompatível, e, kit
EP2823858A1 (en) 2013-07-12 2015-01-14 Brossel, Rémy System generating a constraint field, and medical device implementing the same
WO2015020936A1 (en) 2013-08-06 2015-02-12 Ut-Battelle, Llc Local thermal actuation of material surfaces via micro- and nanowire heating for the prevention of cellular attachment and biological fouling
US10234608B2 (en) 2013-11-15 2019-03-19 University Of Utah Research Foundation Nanoparticle light filtering method and apparatus
WO2015073933A1 (en) 2013-11-15 2015-05-21 University Of Utah Research Foundation Nanoparticle light filtering method and apparatus
CN103752849B (zh) * 2014-02-13 2016-02-24 华东理工大学 制备稳定纳米银的方法
US9814631B2 (en) * 2014-03-03 2017-11-14 Sambhu Choudhury Container for surgical absorbent articles
WO2015161181A1 (en) 2014-04-17 2015-10-22 Boston Scientific Scimed, Inc. Devices and methods for therapeutic heat treatment
WO2015168379A2 (en) 2014-04-30 2015-11-05 President And Fellows Of Harvard College Combination vaccine devices and methods of killing cancer cells
CN103989552B (zh) * 2014-05-07 2015-10-28 江苏达胜伦比亚生物科技有限公司 一种医用水凝胶凉贴
CZ27466U1 (cs) * 2014-08-21 2014-11-10 Univerzita Tomáše Bati ve Zlíně Biomateriál na bázi hydrogelu citlivý na magnetické podněty
RU2616258C2 (ru) * 2014-11-10 2017-04-13 федеральное государственное автономное образовательное учреждение высшего образования "Московский физико-технический институт (государственный университет)" Способ получения полимерных наночастиц низкосиалированного эритропоэтина с высокой степенью сорбции для лечения неврологических заболеваний
HK1247861A1 (zh) 2015-01-30 2018-10-05 President And Fellows Of Harvard College 用於癌症治疗的肿瘤周围和肿瘤内部材料
CN107708756A (zh) 2015-04-10 2018-02-16 哈佛学院院长等 免疫细胞捕获装置及其制备和使用方法
MA43100A (fr) 2015-05-28 2018-09-05 Nanobiotix Nanoparticules à utiliser en tant que vaccin thérapeutique
EP3344301B1 (en) * 2015-09-04 2020-09-02 University of the Witwatersrand, Johannesburg Biodegradable implant
CN108289856A (zh) 2015-10-07 2018-07-17 波士顿科学国际有限公司 用以提高热疗的感应加热效率的具有不同居里温度的LaFeSiH磁性纳米粒子混合物
RU167739U1 (ru) * 2015-12-02 2017-01-10 Федеральное государственное бюджетное учреждение науки Красноярский научный центр Сибирского отделения Российской академии наук (ФГБУН КНЦ СО РАН) Нанодиски для разрушения опухолевых клеток
CN115487351A (zh) 2016-02-06 2022-12-20 哈佛学院校长同事会 重塑造血巢以重建免疫
ES3032115T3 (en) 2016-07-13 2025-07-15 Harvard College Antigen-presenting cell-mimetic scaffolds and methods for making and using the same
WO2018026884A1 (en) 2016-08-02 2018-02-08 President And Fellows Of Harvard College Biomaterials for modulating immune responses
US11352491B2 (en) * 2016-09-08 2022-06-07 Schaefer Kalk Gmbh & Co. Kg Calcium-salt-containing composite powder having microstructured particles
EP3305334A1 (en) * 2016-10-06 2018-04-11 Universitätsklinikum Jena Magnetic composition and medical material for stimulating vascularisation in internal or external wound of the body
WO2018105779A1 (ko) * 2016-12-07 2018-06-14 서울대학교산학협력단 바이오 패치, 바이오 히터, 바이오 센서, 및 바이오 전자 패치 장치
CZ2016804A3 (cs) * 2016-12-16 2018-04-18 Synthesia, A. S. Supramolekulární komplex oxycelulózové matrice s taxolovým derivátem s postupným uvolňováním taxolového derivátu a jeho použití
US12396951B2 (en) 2016-12-27 2025-08-26 Upexmed Co. Ltd. Prevention of local tumor recurrence following surgery using sustainedand/or delayed release of medicaments contained in micro-particles
WO2018125862A1 (en) * 2016-12-27 2018-07-05 Soon Kap Hahn Prevention of local tumor recurrence following surgery using sustained and/or delayed release of medicaments contained in micro-particles
DE102017214576A1 (de) * 2017-08-21 2019-02-21 Universität Bielefeld Anorganisch-organischer Nanokomposit mit zellbiologischer und sensorischer Aktivität
RU181003U1 (ru) * 2017-11-14 2018-07-03 Федеральное государственное бюджетное образовательное учреждение высшего образования "Саратовский государственный технический университет имени Гагарина Ю.А." (СГТУ имени Гагарина Ю.А.) Пластинчатый дентальный имплантат для многопозиционного протезирования
RU181004U1 (ru) * 2017-11-14 2018-07-03 Федеральное государственное бюджетное образовательное учреждение высшего образования "Саратовский государственный технический университет имени Гагарина Ю.А." (СГТУ имени Гагарина Ю.А.) Пластинчатый дентальный имплантат для многопозиционного протезирования
RU181002U1 (ru) * 2017-12-25 2018-07-03 Федеральное государственное бюджетное образовательное учреждение высшего образования "Саратовский государственный технический университет имени Гагарина Ю.А." (СГТУ имени Гагарина Ю.А.) Пластинчатый дентальный имплантат для многопозиционного протезирования
KR102200787B1 (ko) * 2017-12-29 2021-01-12 한경대학교 산학협력단 나노셀룰로오스를 이용한 습윤성 탄력붕대
CN108912628A (zh) * 2018-05-31 2018-11-30 苏州乔纳森新材料科技有限公司 一种插管用抗菌纳米材料的制备方法
WO2020061129A1 (en) 2018-09-19 2020-03-26 President And Fellows Of Harvard College Compositions and methods for labeling and modulation of cells in vitro and in vivo
RU189308U1 (ru) * 2019-03-22 2019-05-21 Артем Олегович Бахметьев Трансдермальный пластырь
RU189268U1 (ru) * 2019-03-22 2019-05-17 Артем Олегович Бахметьев Акупунктурная игла
KR102372213B1 (ko) * 2019-09-09 2022-03-08 한국화학연구원 히알루론산 또는 그의 염 및 폴리페놀 화합물을 포함하는 수분해성 필름
IL295186A (en) 2020-01-31 2022-09-01 Magforce Ag A preparation containing magnetic metallic particles coated with alkoxysilane
CN111921003B (zh) * 2020-09-04 2022-06-03 东南大学 一种磁响应热疗可控降解栓塞微球及其制备方法与应用
CN112972778B (zh) * 2021-02-05 2022-05-27 华中科技大学 一种人工膀胱铁磁复合物及其制备方法
CN112972779B (zh) * 2021-02-05 2022-07-12 武汉磁济科技有限公司 一种植入式柔性磁响应人工膀胱基体及其制造方法
CN112933288B (zh) * 2021-02-08 2022-02-22 四川大学 兼具止血和术后抗肿瘤功能的交联止血海绵及其制备方法
US20230061188A1 (en) * 2021-08-30 2023-03-02 Apple Inc. Enhanced mems sensor embedded heater
DE102022115394A1 (de) 2022-06-21 2023-12-21 Rheinisch-Westfälische Technische Hochschule (Rwth) Aachen Implantat und Anordnung aufweisend eine Strahlungsquelle und ein Implantat

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH31064A (en) * 1990-09-07 1998-02-05 Nycomed As Of Nycoveten Polymers containing diester units.
US5411730A (en) 1993-07-20 1995-05-02 Research Corporation Technologies, Inc. Magnetic microparticles
DE4428851C2 (de) 1994-08-04 2000-05-04 Diagnostikforschung Inst Eisen enthaltende Nanopartikel, ihre Herstellung und Anwendung in der Diagnostik und Therapie
US7611533B2 (en) * 1995-06-07 2009-11-03 Cook Incorporated Coated implantable medical device
DE19614136A1 (de) 1996-04-10 1997-10-16 Inst Neue Mat Gemein Gmbh Verfahren zur Herstellung agglomeratfreier nanoskaliger Eisenoxidteilchen mit hydrolysebeständigem Überzug
JPH10328314A (ja) * 1997-06-02 1998-12-15 Nippon Electric Glass Co Ltd 温熱治療用セメント材料及び温熱治療用インプラント材
JPH10337335A (ja) * 1997-06-06 1998-12-22 Nippon Electric Glass Co Ltd 温熱治療用インプラント材
DE19726282A1 (de) 1997-06-20 1998-12-24 Inst Neue Mat Gemein Gmbh Nanoskalige Teilchen mit einem von mindestens zwei Schalen umgebenen eisenoxid-haltigen Kern
US20030073663A1 (en) * 1997-06-25 2003-04-17 David M Wiseman Bioabsorbable medical devices from oxidized polysaccharides
US6267782B1 (en) * 1997-11-20 2001-07-31 St. Jude Medical, Inc. Medical article with adhered antimicrobial metal
EP1208005B1 (en) * 1999-07-16 2010-04-07 Wm. MARSH RICE UNIVERSITY Temperature-sensitive polymer/nanoshell composites for photothermally modulated drug delivery
DE10059151C2 (de) 2000-11-29 2003-10-16 Christoph Alexiou Magnetische Partikel zur zielgerichteten regionalen Therapie und Verwendung derselben
US6527693B2 (en) * 2001-01-30 2003-03-04 Implant Sciences Corporation Methods and implants for providing radiation to a patient
WO2003026618A1 (en) 2001-09-28 2003-04-03 Saoirse Corporation Localized non-invasive biological modulation system
DE10164309A1 (de) * 2001-12-28 2003-07-10 Fraunhofer Ges Forschung Verbesserte strukturiert-funktionale Bindematrices für Biomoleküle
US7101394B2 (en) * 2002-05-02 2006-09-05 Boston Scientific Scimed, Inc. Energetically-controlled delivery of biologically active material from an implanted medical device
WO2004034876A2 (en) * 2002-10-15 2004-04-29 Ferx Incorporated Magnetically guided particles for radiative therapies
ITTO20020994A1 (it) * 2002-11-15 2004-05-16 Torino Politecnico Materiali magnetici biocompatibili per il trattamento del cancro mediante ipertermia, e processi per la loro realizzazione.
DE10350248A1 (de) 2003-10-28 2005-06-16 Magnamedics Gmbh Thermosensitive, biokompatible Polymerträger mit veränderbarer physikalischer Struktur für die Therapie, Diagnostik und Analytik
WO2005065282A2 (en) 2003-12-31 2005-07-21 The Regents Of The University Of California Remote magnetically induced treatment of cancer
WO2005070471A2 (en) 2004-01-20 2005-08-04 Alnis Biosciences, Inc. Articles comprising magnetic material and bioactive agents
CN101010004B (zh) * 2004-07-30 2012-10-03 金伯利-克拉克环球有限公司 抗微生物的装置和组合物
CN101431983A (zh) * 2004-09-28 2009-05-13 香港科技大学 作为生物材料的多功能的超分子水凝胶
DE102005016873A1 (de) * 2005-04-12 2006-10-19 Magforce Nanotechnologies Ag Nanopartikel-Wirstoff-Konjugate
US20090081122A1 (en) * 2005-05-23 2009-03-26 Universite De Geneve Injectable superparamagnetic nanoparticles for treatment by hyperthermia and use for forming an hyperthermic implant
FR2889449B1 (fr) 2005-08-05 2011-06-10 Khorionyx Preparations implantables
DE102005039579B4 (de) 2005-08-19 2022-06-30 Magforce Ag Verfahren zur Einschleusung von therapeutischen Substanzen in Zellen
WO2007095454A2 (en) * 2006-02-10 2007-08-23 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Carbon-encased metal nanoparticles and sponges, methods of synthesis, and methods of use
WO2008089478A2 (en) * 2007-01-19 2008-07-24 Triton Biosystems, Inc. Thermotherapy susceptors and methods of using same

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WO2009100716A2 (de) 2009-08-20
JP2011511684A (ja) 2011-04-14
CA2712832A1 (en) 2009-08-20
DE112009000905A5 (de) 2011-01-20
PT2249804T (pt) 2017-03-20
MX2010008806A (es) 2010-12-21
IL207137A (en) 2015-02-26
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CN101938993A (zh) 2011-01-05
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CA2712832C (en) 2016-05-17
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IL207137A0 (en) 2010-12-30
AU2009214533B2 (en) 2015-01-29
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