JP5646706B2 - Ｃ−グリコシド誘導体の製造方法 - Google Patents

Ｃ−グリコシド誘導体の製造方法 Download PDF

Info

Publication number
JP5646706B2
JP5646706B2 JP2013153374A JP2013153374A JP5646706B2 JP 5646706 B2 JP5646706 B2 JP 5646706B2 JP 2013153374 A JP2013153374 A JP 2013153374A JP 2013153374 A JP2013153374 A JP 2013153374A JP 5646706 B2 JP5646706 B2 JP 5646706B2
Authority
JP
Japan
Prior art keywords
formula
compound
magnesium
reaction
iii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2013153374A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013234194A (ja
JP2013234194A5 (https=
Inventor
冨山　泰
泰 冨山
昌幸 横田
昌幸 横田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kotobuki Seiyaku Co Ltd
Original Assignee
Kotobuki Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kotobuki Seiyaku Co Ltd filed Critical Kotobuki Seiyaku Co Ltd
Priority to JP2013153374A priority Critical patent/JP5646706B2/ja
Publication of JP2013234194A publication Critical patent/JP2013234194A/ja
Priority to PCT/JP2014/068386 priority patent/WO2015012110A1/ja
Priority to TW103125071A priority patent/TW201602128A/zh
Publication of JP2013234194A5 publication Critical patent/JP2013234194A5/ja
Application granted granted Critical
Publication of JP5646706B2 publication Critical patent/JP5646706B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2013153374A 2013-07-24 2013-07-24 Ｃ−グリコシド誘導体の製造方法 Expired - Fee Related JP5646706B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2013153374A JP5646706B2 (ja) 2013-07-24 2013-07-24 Ｃ−グリコシド誘導体の製造方法
PCT/JP2014/068386 WO2015012110A1 (ja) 2013-07-24 2014-07-10 Ｃ－グリコシド誘導体の製造方法
TW103125071A TW201602128A (zh) 2013-07-24 2014-07-22 Ｃ－糖苷衍生物之製造方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2013153374A JP5646706B2 (ja) 2013-07-24 2013-07-24 Ｃ−グリコシド誘導体の製造方法

Publications (3)

Publication Number Publication Date
JP2013234194A JP2013234194A (ja) 2013-11-21
JP2013234194A5 JP2013234194A5 (https=) 2014-10-30
JP5646706B2 true JP5646706B2 (ja) 2014-12-24

Family

ID=49760574

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013153374A Expired - Fee Related JP5646706B2 (ja) 2013-07-24 2013-07-24 Ｃ−グリコシド誘導体の製造方法

Country Status (3)

Country Link
JP (1) JP5646706B2 (https=)
TW (1) TW201602128A (https=)
WO (1) WO2015012110A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9902751B2 (en) 2013-12-30 2018-02-27 Mylan Laboratories Limited Process for the preparation of empagliflozin
CN106188022A (zh) * 2015-04-30 2016-12-07 上海医药工业研究院 伊格列净的制备方法
JP2022028986A (ja) * 2018-12-17 2022-02-17 株式会社トクヤマ Ｃ－アリールヒドロキシグリコキシド誘導体の製造方法
WO2020129899A1 (ja) * 2018-12-17 2020-06-25 株式会社トクヤマ Ｃ－アリールヒドロキシグリコキシド誘導体の製造方法
JP7738857B2 (ja) 2020-11-18 2025-09-16 株式会社トクヤマ ケトン誘導体の製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2567571T3 (es) * 2003-03-14 2016-04-25 Astellas Pharma Inc. Derivados de C-glucósido y sales de los mismos
KR101100072B1 (ko) * 2006-12-21 2011-12-29 고토부키 세이야쿠 가부시키가이샤 Ｃ-글리코시드 유도체의 제조방법 및 이의 합성 중간체
JP2010519273A (ja) * 2007-02-21 2010-06-03 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 四置換グルコピラノシル化ベンゼン誘導体、このような化合物を含む薬物、それらの使用及びそれらの製造方法
AU2009270936B2 (en) * 2008-07-15 2014-12-18 Theracos, Inc. Deuterated benzylbenzene derivatives and methods of use

Also Published As

Publication number Publication date
JP2013234194A (ja) 2013-11-21
WO2015012110A1 (ja) 2015-01-29
TW201602128A (zh) 2016-01-16

Similar Documents

Publication Publication Date Title
JP5646706B2 (ja) Ｃ−グリコシド誘導体の製造方法
CN107501112B (zh) 一种手性β-氨基酸的手性合成方法及医药中间体的合成方法
JPWO2008075736A1 (ja) Ｃ−グリコシド誘導体の製造方法及びその合成中間体
JP2012531407A (ja) トリサイクリック誘導体の製造方法
CN112079781A (zh) 5-溴-1-甲基-1h-吡唑-3-胺的合成方法
US7049455B2 (en) Process for producing shogaols and intermediates for the synthesis thereof
CN108727323B (zh) 一种氮杂环卡宾催化合成三氟甲基取代高异黄酮类化合物的方法
CN118598812A (zh) 石杉碱甲关键中间体的合成方法
JP5305697B2 (ja) α−Ｄ−マンノピラノシド誘導体の製造方法
KR102436114B1 (ko) 신규한 이노토디올의 제조방법
CN112592306B (zh) 吡咯啉酮类化合物及其合成方法
WO2014132940A1 (ja) α－ハロテトラアシルグルコースの製造方法
CN101891716B (zh) 一种S-β-羟基-γ-丁内酯的合成方法
KR20110111782A (ko) 디페닐아세테이트 유도체의 새로운 제조방법
JP5328183B2 (ja) グルコシドエステル誘導体の製造方法
CN106146530A (zh) 一种合成cephalosporolides E,F,H,I的新方法
CN115819307B (zh) 一种前列腺素e1的制备方法
WO2000035898A1 (en) HYDRONAPHTHO[2,3-c]FURAN DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF
JP2015013851A (ja) （２Ｒ）−２−フルオロ−２−Ｃ−メチル−Ｄ−リボノ−γ−ラクトン類の製造方法
WO2014108011A1 (zh) 恩替卡韦中间体及其制备方法
CN117142996A (zh) 单胺基抑制剂类中间体及其合成方法与应用
JP4528884B2 (ja) ゲムシタビンの合成に有用なナフタレン−２−カルボキシレート誘導体及びその製造方法
CN109180564A (zh) 一种哌啶及其衍生物的制备方法
JPWO2011065351A1 (ja) シクロヘキサン誘導体の製造方法
CN104140412B (zh) 用于制备新木榄二硫醇的中间体、其合成方法、中间体和用途

Legal Events

Date Code Title Description
A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20140520

A521 Written amendment

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20140520

A521 Written amendment

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140910

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20140910

A871 Explanation of circumstances concerning accelerated examination

Free format text: JAPANESE INTERMEDIATE CODE: A871

Effective date: 20140910

A975 Report on accelerated examination

Free format text: JAPANESE INTERMEDIATE CODE: A971005

Effective date: 20140930

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20141007

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20141105

R150 Certificate of patent or registration of utility model

Ref document number: 5646706

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

LAPS Cancellation because of no payment of annual fees