JP5635266B2 - 安定なチアクミシン組成物 - Google Patents

安定なチアクミシン組成物 Download PDF

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Publication number
JP5635266B2
JP5635266B2 JP2009546419A JP2009546419A JP5635266B2 JP 5635266 B2 JP5635266 B2 JP 5635266B2 JP 2009546419 A JP2009546419 A JP 2009546419A JP 2009546419 A JP2009546419 A JP 2009546419A JP 5635266 B2 JP5635266 B2 JP 5635266B2
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JP
Japan
Prior art keywords
composition
composition according
dosage form
solid dosage
pharmaceutical composition
Prior art date
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Application number
JP2009546419A
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English (en)
Japanese (ja)
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JP2010516677A5 (enExample
JP2010516677A (ja
Inventor
サングビ，スケツ
ローチ，マーク
ゾウ，ジョセフ，エフ．
ヒー，ピン
ミッテルバーグ，マイケル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Optimer Pharmaceuticals LLC
Original Assignee
Optimer Pharmaceuticals LLC
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Publication date
Application filed by Optimer Pharmaceuticals LLC filed Critical Optimer Pharmaceuticals LLC
Publication of JP2010516677A publication Critical patent/JP2010516677A/ja
Publication of JP2010516677A5 publication Critical patent/JP2010516677A5/ja
Application granted granted Critical
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2009546419A 2007-01-19 2008-01-17 安定なチアクミシン組成物 Active JP5635266B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88113707P 2007-01-19 2007-01-19
US60/881,137 2007-01-19
PCT/US2008/000591 WO2008091518A1 (en) 2007-01-19 2008-01-17 Compositions of stable tiacumicins

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014129106A Division JP5995331B2 (ja) 2007-01-19 2014-06-24 安定なチアクミシン組成物

Publications (3)

Publication Number Publication Date
JP2010516677A JP2010516677A (ja) 2010-05-20
JP2010516677A5 JP2010516677A5 (enExample) 2011-03-03
JP5635266B2 true JP5635266B2 (ja) 2014-12-03

Family

ID=39641896

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2009546419A Active JP5635266B2 (ja) 2007-01-19 2008-01-17 安定なチアクミシン組成物
JP2014129106A Active JP5995331B2 (ja) 2007-01-19 2014-06-24 安定なチアクミシン組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014129106A Active JP5995331B2 (ja) 2007-01-19 2014-06-24 安定なチアクミシン組成物

Country Status (22)

Country Link
US (2) US20080176927A1 (enExample)
EP (1) EP2121716B1 (enExample)
JP (2) JP5635266B2 (enExample)
KR (1) KR101491729B1 (enExample)
CN (2) CN102015747A (enExample)
BR (1) BRPI0806713A8 (enExample)
CA (1) CA2676003C (enExample)
CY (1) CY1117237T1 (enExample)
DK (1) DK2121716T3 (enExample)
ES (1) ES2560669T3 (enExample)
HR (1) HRP20151438T1 (enExample)
HU (1) HUE028671T2 (enExample)
IL (1) IL199941A (enExample)
MX (1) MX2009007784A (enExample)
NZ (1) NZ578493A (enExample)
PL (1) PL2121716T3 (enExample)
PT (1) PT2121716E (enExample)
RU (1) RU2484829C2 (enExample)
SI (1) SI2121716T1 (enExample)
TW (1) TWI474820B (enExample)
WO (1) WO2008091518A1 (enExample)
ZA (1) ZA200905134B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7906489B2 (en) 2004-05-14 2011-03-15 Optimer Pharmaceuticals, Inc. 18-membered macrocycles and analogs thereof
US7378508B2 (en) 2007-01-22 2008-05-27 Optimer Pharmaceuticals, Inc. Polymorphic crystalline forms of tiacumicin B
TWI523654B (zh) 2007-11-27 2016-03-01 默沙東藥廠 抗生素巨環化合物以及其製造及使用之方法
BR112012029259A8 (pt) * 2010-05-18 2021-03-23 Optimer Pharmaceuticals Inc tratamento de infecção por clostridium difficile em pacientes sob terapia de antibióticos
WO2011146624A2 (en) * 2010-05-18 2011-11-24 Optimer Pharmaceuticals, Inc. Methods of treating recurring bacterial infection
EP2575487B1 (en) * 2010-06-02 2017-10-18 Diffusion Pharmaceuticals Llc Oral formulations of bipolar trans carotenoids
MX2013009033A (es) * 2011-02-04 2013-09-06 Optimer Pharmaceuticals Inc Tratamiento de infecciones bacterianas.
ITMI20120560A1 (it) 2012-04-05 2013-10-06 Olon Spa Procedimento per la purificazione della tiacumicina b
JO3464B1 (ar) * 2013-01-15 2020-07-05 Astellas Pharma Europe Ltd التركيبات الخاصة بمركبات التياكوميسين
US20150141356A1 (en) * 2013-11-15 2015-05-21 Optimer Pharmaceuticals, Inc. Treatment of Clostridium Difficile Infection in High Risk Patients
WO2015127955A1 (en) 2014-02-25 2015-09-03 Olon S.P.A. A new polymorph of tiacumicin b and process for preparation thereof
PT3139932T (pt) * 2014-05-09 2018-11-14 Astellas Pharma Europe Ltd Regime de tratamento para composto de tiacumicina
CN110037992B (zh) * 2019-05-28 2021-05-28 杭州华东医药集团新药研究院有限公司 一种稳定的非达霉素组合物
CN112353774B (zh) * 2020-11-17 2022-08-23 浙江汇能生物股份有限公司 一种那西肽风味咀嚼片及其制备方法及其在犬魏氏梭菌病上的用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05192094A (ja) * 1991-09-03 1993-08-03 Takeda Chem Ind Ltd 造粒組成物
US5583115A (en) * 1995-05-09 1996-12-10 Abbott Laboratories Dialkyltiacumicin compounds
WO2002032427A1 (en) * 2000-10-20 2002-04-25 Galephar M/F Stable oral formulation containing benzimidazole derivative
US20030099699A1 (en) * 2001-11-13 2003-05-29 Hanshew Dwight D. Storage stable thyroxine active drug formulations and methods for their production
AU2003251902B2 (en) * 2002-07-29 2008-03-06 Merck Sharp & Dohme Llc Tiacumicin production
US9211259B2 (en) * 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
EP1572164A2 (en) * 2002-12-18 2005-09-14 Pain Therapeutics, Inc. Oral dosage forms with therapeutically active agents in controlled release cores and immediate release gelatin capsule coats
US7906489B2 (en) * 2004-05-14 2011-03-15 Optimer Pharmaceuticals, Inc. 18-membered macrocycles and analogs thereof
MX2007009196A (es) 2005-01-31 2009-02-25 Optimer Pharmaceuticals Inc Compuestos macrocilicos de 18 miembros y analogos de los mismos.

Also Published As

Publication number Publication date
HRP20151438T1 (hr) 2016-01-29
KR101491729B1 (ko) 2015-02-09
NZ578493A (en) 2012-02-24
US20080176927A1 (en) 2008-07-24
ES2560669T3 (es) 2016-02-22
CN102015747A (zh) 2011-04-13
MX2009007784A (es) 2010-02-11
IL199941A (en) 2016-02-29
EP2121716A1 (en) 2009-11-25
CA2676003C (en) 2012-04-10
ZA200905134B (en) 2013-08-28
EP2121716A4 (en) 2013-06-12
US20130065844A1 (en) 2013-03-14
AU2008209623A2 (en) 2010-01-28
JP2010516677A (ja) 2010-05-20
BRPI0806713A8 (pt) 2017-04-18
EP2121716B1 (en) 2015-12-09
BRPI0806713A2 (pt) 2011-09-13
CN105169396A (zh) 2015-12-23
AU2008209623A1 (en) 2008-07-31
IL199941A0 (en) 2010-04-15
TW200938187A (en) 2009-09-16
JP2014205701A (ja) 2014-10-30
TWI474820B (zh) 2015-03-01
RU2009128612A (ru) 2011-02-27
SI2121716T1 (sl) 2016-03-31
RU2484829C2 (ru) 2013-06-20
PT2121716E (pt) 2016-03-03
HUE028671T2 (en) 2016-12-28
WO2008091518A1 (en) 2008-07-31
KR20090107061A (ko) 2009-10-12
DK2121716T3 (en) 2016-03-14
CY1117237T1 (el) 2017-04-05
PL2121716T3 (pl) 2016-04-29
CA2676003A1 (en) 2008-07-31
JP5995331B2 (ja) 2016-09-21

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