JP5632383B2 - 即時使用のための乾燥され、放射線照射された皮膚同等物 - Google Patents

即時使用のための乾燥され、放射線照射された皮膚同等物 Download PDF

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JP5632383B2
JP5632383B2 JP2011535637A JP2011535637A JP5632383B2 JP 5632383 B2 JP5632383 B2 JP 5632383B2 JP 2011535637 A JP2011535637 A JP 2011535637A JP 2011535637 A JP2011535637 A JP 2011535637A JP 5632383 B2 JP5632383 B2 JP 5632383B2
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skin equivalent
skin
tissue
irradiated
human
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JP2012508064A5 (en:Method
JP2012508064A (ja
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カマー，アレン，アール．
アレン−ホフマン，ビー．，リン
スティグリッツ，バリー
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ストラタテック コーポレーション
ストラタテック コーポレーション
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/10—Hair or skin implants
    • A61F2/105—Skin implants, e.g. artificial skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3813—Epithelial cells, e.g. keratinocytes, urothelial cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
JP2011535637A 2008-11-04 2009-11-04 即時使用のための乾燥され、放射線照射された皮膚同等物 Active JP5632383B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11115308P 2008-11-04 2008-11-04
US61/111,153 2008-11-04
PCT/US2009/063217 WO2010053948A1 (en) 2008-11-04 2009-11-04 Dried and irradiated skin equivalents for ready use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014156571A Division JP2014221417A (ja) 2008-11-04 2014-07-31 即時使用のための乾燥され、放射線照射された皮膚同等物

Publications (3)

Publication Number Publication Date
JP2012508064A JP2012508064A (ja) 2012-04-05
JP2012508064A5 JP2012508064A5 (en:Method) 2012-12-13
JP5632383B2 true JP5632383B2 (ja) 2014-11-26

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Family Applications (2)

Application Number Title Priority Date Filing Date
JP2011535637A Active JP5632383B2 (ja) 2008-11-04 2009-11-04 即時使用のための乾燥され、放射線照射された皮膚同等物
JP2014156571A Pending JP2014221417A (ja) 2008-11-04 2014-07-31 即時使用のための乾燥され、放射線照射された皮膚同等物

Family Applications After (1)

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JP2014156571A Pending JP2014221417A (ja) 2008-11-04 2014-07-31 即時使用のための乾燥され、放射線照射された皮膚同等物

Country Status (10)

Country Link
US (5) US8580314B2 (en:Method)
EP (1) EP2352472B1 (en:Method)
JP (2) JP5632383B2 (en:Method)
CN (1) CN102271634B (en:Method)
AU (1) AU2009313656B2 (en:Method)
CA (1) CA2742595C (en:Method)
DK (1) DK2352472T3 (en:Method)
ES (1) ES2621324T3 (en:Method)
PT (1) PT2352472T (en:Method)
WO (1) WO2010053948A1 (en:Method)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009065005A1 (en) 2007-11-14 2009-05-22 Stratatech Corporation Cold storage of organotypically cultured skin equivalents for clinical applications
AU2009313656B2 (en) 2008-11-04 2014-02-20 Stratatech Corporation Dried and irradiated skin equivalents for ready use
US20100330046A1 (en) * 2009-05-21 2010-12-30 Stratatech Corporation Human skin substitutes expressing il-12
ES2705043T3 (es) * 2013-03-13 2019-03-21 Stratatech Corp Criopreservación de sustitutos de piel humana viables
KR101701396B1 (ko) 2014-10-28 2017-02-01 주식회사 엑티저 오디오 신호 처리 장치 및 방법
US20220287298A1 (en) * 2017-01-27 2022-09-15 Stratatech Corporation Tissue container systems
JP2022549688A (ja) * 2019-09-27 2022-11-28 ストラタテック コーポレーション 急性創傷を治療し、転帰を改善するための方法
JP2023525231A (ja) * 2020-05-13 2023-06-15 ストラタテック コーポレーション 生存能力のある生物工学によって作られた皮膚構築物

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US4485096A (en) 1982-02-26 1984-11-27 Massachusetts Institute Of Technology Tissue-equivalent and method for preparation thereof
IL95429A (en) 1989-09-15 1997-09-30 Organogenesis Living tissue equivalents comprising hydrated collagen lattice and a collagen gel and their production
RU2135191C1 (ru) 1990-04-24 1999-08-27 Ортек Интернэшнл, Инк. Композиционный эквивалент живой кожи, способ его получения, тест-набор
ATE307599T1 (de) * 1991-11-20 2005-11-15 Innogenetics Nv Keratinozyt-abstammende granulate zur verwendung als wundheilendes mittel
US6585969B1 (en) 1991-11-20 2003-07-01 N. V. Innogenetics S.A. Non-viable keratinocyte cell composition or lysate for promoting wound healing
JPH10509610A (ja) * 1994-11-09 1998-09-22 クリ・ハークチ，ワリド 創傷修復用包帯およびそれらの保存法
US5693332C1 (en) 1995-08-11 2001-01-09 Univ California Human keratinocytes supported on a hydrophilic membrane and methods of using same to effect wound closure
JP3377354B2 (ja) * 1995-12-25 2003-02-17 株式会社メニコン 人工皮膚
US5968546A (en) 1997-05-16 1999-10-19 Baur; Marcus Keratinocyte culture from precursor cells
US5989837A (en) 1998-07-13 1999-11-23 Wisconsin Alumni Research Foundation Immortalized human keratinocyte cell line
JP3738273B2 (ja) * 1999-07-20 2006-01-25 ディーエフビー ファーマシューティカルズ， インコーポレイテッド 改良ケラチノサイト培養物およびその使用
US6866686B2 (en) 2000-01-28 2005-03-15 Cryolife, Inc. Tissue graft
US6974697B2 (en) 2001-03-02 2005-12-13 Stratech Corporation Skin substitutes with improved barrier function
NZ549526A (en) 2001-03-02 2009-06-26 Stratatech Corp Human skin equivalents comprising near diploid immortalized keratinocyte cells (NIKS)
WO2003093418A2 (en) 2002-04-30 2003-11-13 Stratech Corporation Keratinocytes expressing exogenous angiogenic growth factors
WO2004013606A2 (en) 2002-08-02 2004-02-12 Stratatech Corporation Species specific dna detection
US7993922B2 (en) * 2002-10-18 2011-08-09 Reliance Life Sciences Pvt. Ltd. Three-dimensional tissue equivalent using macromass culture
AU2004247072B2 (en) 2003-05-30 2007-09-13 Stratatech Corporation Room temperature storage of organs
CA2758178C (en) 2003-08-01 2016-10-11 Stratatech Corporation Human skin equivalents expressing exogenous polypeptides
WO2005012492A2 (en) * 2003-08-01 2005-02-10 Stratatech Corporation Human skin equivalents expressing exogenous polypeptides
JP5706058B2 (ja) * 2004-02-13 2015-04-22 スミス アンド ネフュー オルトペディクス アクチェンゲゼルシャフト 創傷治療組成物
US20060141627A1 (en) 2004-11-18 2006-06-29 Stratatech Corporation Vectors for stable gene expression
US9163076B2 (en) 2005-03-01 2015-10-20 Stratatech Corporation Human skin equivalents expressing exogenous polypeptides
ES2622508T3 (es) 2005-03-17 2017-07-06 Stratatech Corporation Sustitutos de piel con pureza mejorada
CN100400655C (zh) * 2005-12-02 2008-07-09 王平安 组织工程化细胞外基质的制备方法
WO2009065005A1 (en) 2007-11-14 2009-05-22 Stratatech Corporation Cold storage of organotypically cultured skin equivalents for clinical applications
AU2009313656B2 (en) 2008-11-04 2014-02-20 Stratatech Corporation Dried and irradiated skin equivalents for ready use
US20100330046A1 (en) 2009-05-21 2010-12-30 Stratatech Corporation Human skin substitutes expressing il-12

Also Published As

Publication number Publication date
AU2009313656B2 (en) 2014-02-20
JP2014221417A (ja) 2014-11-27
DK2352472T3 (en) 2017-04-10
AU2009313656A1 (en) 2010-05-14
JP2012508064A (ja) 2012-04-05
US9867904B2 (en) 2018-01-16
US20140288165A1 (en) 2014-09-25
US20170087276A1 (en) 2017-03-30
EP2352472A4 (en) 2014-03-05
US20140067064A1 (en) 2014-03-06
US9526811B2 (en) 2016-12-27
CA2742595A1 (en) 2010-05-14
US8580314B2 (en) 2013-11-12
CN102271634A (zh) 2011-12-07
US20100119615A1 (en) 2010-05-13
US8992997B2 (en) 2015-03-31
EP2352472A1 (en) 2011-08-10
WO2010053948A1 (en) 2010-05-14
US20150196686A1 (en) 2015-07-16
US8685463B2 (en) 2014-04-01
ES2621324T3 (es) 2017-07-03
CN102271634B (zh) 2015-01-14
CA2742595C (en) 2014-04-01
PT2352472T (pt) 2017-04-11
EP2352472B1 (en) 2017-01-04

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