DK2352472T3 - Dried and irradiated skin equivalents ready to use - Google Patents
Dried and irradiated skin equivalents ready to use Download PDFInfo
- Publication number
- DK2352472T3 DK2352472T3 DK09825325.5T DK09825325T DK2352472T3 DK 2352472 T3 DK2352472 T3 DK 2352472T3 DK 09825325 T DK09825325 T DK 09825325T DK 2352472 T3 DK2352472 T3 DK 2352472T3
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- DK
- Denmark
- Prior art keywords
- skin equivalent
- tissues
- skin
- cells
- irradiated
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
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- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61F2/105—Skin implants, e.g. artificial skin
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3813—Epithelial cells, e.g. keratinocytes, urothelial cells
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/60—Materials for use in artificial skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Transplantation (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Botany (AREA)
- Molecular Biology (AREA)
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- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
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| PCT/US2009/063217 WO2010053948A1 (en) | 2008-11-04 | 2009-11-04 | Dried and irradiated skin equivalents for ready use |
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| EP (1) | EP2352472B1 (en:Method) |
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| PT (1) | PT2352472T (en:Method) |
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| WO2009065005A1 (en) | 2007-11-14 | 2009-05-22 | Stratatech Corporation | Cold storage of organotypically cultured skin equivalents for clinical applications |
| AU2009313656B2 (en) | 2008-11-04 | 2014-02-20 | Stratatech Corporation | Dried and irradiated skin equivalents for ready use |
| US20100330046A1 (en) * | 2009-05-21 | 2010-12-30 | Stratatech Corporation | Human skin substitutes expressing il-12 |
| ES2705043T3 (es) * | 2013-03-13 | 2019-03-21 | Stratatech Corp | Criopreservación de sustitutos de piel humana viables |
| KR101701396B1 (ko) | 2014-10-28 | 2017-02-01 | 주식회사 엑티저 | 오디오 신호 처리 장치 및 방법 |
| US20220287298A1 (en) * | 2017-01-27 | 2022-09-15 | Stratatech Corporation | Tissue container systems |
| JP2022549688A (ja) * | 2019-09-27 | 2022-11-28 | ストラタテック コーポレーション | 急性創傷を治療し、転帰を改善するための方法 |
| JP2023525231A (ja) * | 2020-05-13 | 2023-06-15 | ストラタテック コーポレーション | 生存能力のある生物工学によって作られた皮膚構築物 |
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| US4485096A (en) | 1982-02-26 | 1984-11-27 | Massachusetts Institute Of Technology | Tissue-equivalent and method for preparation thereof |
| IL95429A (en) | 1989-09-15 | 1997-09-30 | Organogenesis | Living tissue equivalents comprising hydrated collagen lattice and a collagen gel and their production |
| RU2135191C1 (ru) | 1990-04-24 | 1999-08-27 | Ортек Интернэшнл, Инк. | Композиционный эквивалент живой кожи, способ его получения, тест-набор |
| ATE307599T1 (de) * | 1991-11-20 | 2005-11-15 | Innogenetics Nv | Keratinozyt-abstammende granulate zur verwendung als wundheilendes mittel |
| US6585969B1 (en) | 1991-11-20 | 2003-07-01 | N. V. Innogenetics S.A. | Non-viable keratinocyte cell composition or lysate for promoting wound healing |
| JPH10509610A (ja) * | 1994-11-09 | 1998-09-22 | クリ・ハークチ，ワリド | 創傷修復用包帯およびそれらの保存法 |
| US5693332C1 (en) | 1995-08-11 | 2001-01-09 | Univ California | Human keratinocytes supported on a hydrophilic membrane and methods of using same to effect wound closure |
| JP3377354B2 (ja) * | 1995-12-25 | 2003-02-17 | 株式会社メニコン | 人工皮膚 |
| US5968546A (en) | 1997-05-16 | 1999-10-19 | Baur; Marcus | Keratinocyte culture from precursor cells |
| US5989837A (en) | 1998-07-13 | 1999-11-23 | Wisconsin Alumni Research Foundation | Immortalized human keratinocyte cell line |
| JP3738273B2 (ja) * | 1999-07-20 | 2006-01-25 | ディーエフビー ファーマシューティカルズ， インコーポレイテッド | 改良ケラチノサイト培養物およびその使用 |
| US6866686B2 (en) | 2000-01-28 | 2005-03-15 | Cryolife, Inc. | Tissue graft |
| US6974697B2 (en) | 2001-03-02 | 2005-12-13 | Stratech Corporation | Skin substitutes with improved barrier function |
| NZ549526A (en) | 2001-03-02 | 2009-06-26 | Stratatech Corp | Human skin equivalents comprising near diploid immortalized keratinocyte cells (NIKS) |
| WO2003093418A2 (en) | 2002-04-30 | 2003-11-13 | Stratech Corporation | Keratinocytes expressing exogenous angiogenic growth factors |
| WO2004013606A2 (en) | 2002-08-02 | 2004-02-12 | Stratatech Corporation | Species specific dna detection |
| US7993922B2 (en) * | 2002-10-18 | 2011-08-09 | Reliance Life Sciences Pvt. Ltd. | Three-dimensional tissue equivalent using macromass culture |
| AU2004247072B2 (en) | 2003-05-30 | 2007-09-13 | Stratatech Corporation | Room temperature storage of organs |
| CA2758178C (en) | 2003-08-01 | 2016-10-11 | Stratatech Corporation | Human skin equivalents expressing exogenous polypeptides |
| WO2005012492A2 (en) * | 2003-08-01 | 2005-02-10 | Stratatech Corporation | Human skin equivalents expressing exogenous polypeptides |
| JP5706058B2 (ja) * | 2004-02-13 | 2015-04-22 | スミス アンド ネフュー オルトペディクス アクチェンゲゼルシャフト | 創傷治療組成物 |
| US20060141627A1 (en) | 2004-11-18 | 2006-06-29 | Stratatech Corporation | Vectors for stable gene expression |
| US9163076B2 (en) | 2005-03-01 | 2015-10-20 | Stratatech Corporation | Human skin equivalents expressing exogenous polypeptides |
| ES2622508T3 (es) | 2005-03-17 | 2017-07-06 | Stratatech Corporation | Sustitutos de piel con pureza mejorada |
| CN100400655C (zh) * | 2005-12-02 | 2008-07-09 | 王平安 | 组织工程化细胞外基质的制备方法 |
| WO2009065005A1 (en) | 2007-11-14 | 2009-05-22 | Stratatech Corporation | Cold storage of organotypically cultured skin equivalents for clinical applications |
| AU2009313656B2 (en) | 2008-11-04 | 2014-02-20 | Stratatech Corporation | Dried and irradiated skin equivalents for ready use |
| US20100330046A1 (en) | 2009-05-21 | 2010-12-30 | Stratatech Corporation | Human skin substitutes expressing il-12 |
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2013
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| JP2014221417A (ja) | 2014-11-27 |
| AU2009313656A1 (en) | 2010-05-14 |
| JP2012508064A (ja) | 2012-04-05 |
| US9867904B2 (en) | 2018-01-16 |
| US20140288165A1 (en) | 2014-09-25 |
| US20170087276A1 (en) | 2017-03-30 |
| EP2352472A4 (en) | 2014-03-05 |
| US20140067064A1 (en) | 2014-03-06 |
| US9526811B2 (en) | 2016-12-27 |
| CA2742595A1 (en) | 2010-05-14 |
| US8580314B2 (en) | 2013-11-12 |
| JP5632383B2 (ja) | 2014-11-26 |
| CN102271634A (zh) | 2011-12-07 |
| US20100119615A1 (en) | 2010-05-13 |
| US8992997B2 (en) | 2015-03-31 |
| EP2352472A1 (en) | 2011-08-10 |
| WO2010053948A1 (en) | 2010-05-14 |
| US20150196686A1 (en) | 2015-07-16 |
| US8685463B2 (en) | 2014-04-01 |
| ES2621324T3 (es) | 2017-07-03 |
| CN102271634B (zh) | 2015-01-14 |
| CA2742595C (en) | 2014-04-01 |
| PT2352472T (pt) | 2017-04-11 |
| EP2352472B1 (en) | 2017-01-04 |
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