JP5628796B2 - 性的不能の治療用のメラノコルチンレセプタ特異的ペプチド - Google Patents

性的不能の治療用のメラノコルチンレセプタ特異的ペプチド Download PDF

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JP5628796B2
JP5628796B2 JP2011512730A JP2011512730A JP5628796B2 JP 5628796 B2 JP5628796 B2 JP 5628796B2 JP 2011512730 A JP2011512730 A JP 2011512730A JP 2011512730 A JP2011512730 A JP 2011512730A JP 5628796 B2 JP5628796 B2 JP 5628796B2
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peptide
peptides
cyclic
cyclic peptide
acid
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JP2011522839A (ja
JP2011522839A5 (enExample
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シー，イ−クン
シャルマ，シュッブ，ディー．
ヤン，ウェイ
チェン，シン
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Palatin Technologies Inc
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Palatin Technologies Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/68—Melanocyte-stimulating hormone [MSH]
    • C07K14/685—Alpha-melanotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2011512730A 2008-06-09 2009-06-08 性的不能の治療用のメラノコルチンレセプタ特異的ペプチド Expired - Fee Related JP5628796B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5991008P 2008-06-09 2008-06-09
US61/059,910 2008-06-09
PCT/US2009/046571 WO2009152079A1 (en) 2008-06-09 2009-06-08 Melanocortin receptor-specific peptides for treatment of sexual dysfunction

Publications (3)

Publication Number Publication Date
JP2011522839A JP2011522839A (ja) 2011-08-04
JP2011522839A5 JP2011522839A5 (enExample) 2012-06-07
JP5628796B2 true JP5628796B2 (ja) 2014-11-19

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JP2011512730A Expired - Fee Related JP5628796B2 (ja) 2008-06-09 2009-06-08 性的不能の治療用のメラノコルチンレセプタ特異的ペプチド

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Country Link
US (2) US8487073B2 (enExample)
EP (1) EP2300036B1 (enExample)
JP (1) JP5628796B2 (enExample)
KR (1) KR101687037B1 (enExample)
CN (1) CN102131514B (enExample)
AU (1) AU2009257631B2 (enExample)
BR (1) BRPI0909947A2 (enExample)
CA (1) CA2727317C (enExample)
EA (1) EA018630B1 (enExample)
IL (1) IL209867A (enExample)
MX (1) MX2010013436A (enExample)
NZ (1) NZ590254A (enExample)
WO (1) WO2009152079A1 (enExample)
ZA (1) ZA201009165B (enExample)

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JP5628796B2 (ja) 2008-06-09 2014-11-19 パラティン テクノロジーズ, インコーポレイテッドPalatin Technologies, Inc. 性的不能の治療用のメラノコルチンレセプタ特異的ペプチド
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AU2010321738B2 (en) 2009-11-23 2016-07-14 Palatin Technologies, Inc. Melanocortin-1 receptor-specific cyclic peptides
EA201290295A1 (ru) 2009-11-23 2013-01-30 Палатин Текнолоджиз, Инк. Специфичные к рецептору меланокортина-1 линейные пептиды
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CN102702330B (zh) * 2012-03-01 2015-04-01 张嘎 环状核心序列与生物素或穿膜肽相连而成的促黑激素类似物
EP2814501A4 (en) 2012-03-13 2016-03-02 Tensive Controls Inc MELANOCORTINANALOGA WITH INCREASED EFFECTIVENESS AND TRANSPORTATION OF THEREOF
ES2701444T5 (es) * 2012-11-05 2024-05-21 Palatin Technologies Inc Usos de bremelanotida en una terapia para la disfunción sexual femenina
WO2016168388A2 (en) 2015-04-14 2016-10-20 Palatin Technologies, Inc. Therapies for obesity, diabetes and related indications
SG10202101510XA (en) 2015-09-30 2021-03-30 Rhythm Pharmaceuticals Inc Method of treating melanocortin-4 receptor pathway-associated disorders
RU2655763C2 (ru) * 2016-10-24 2018-05-29 Общество С Ограниченной Ответственностью "Айвикс" Фармацевтическая композиция и способ лечения женских сексуальных дисфункций
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US11590209B2 (en) 2020-01-21 2023-02-28 Palatin Technologies, Inc. Use of bremelanotide in patients with controlled hypertension
EP4100042A4 (en) * 2020-02-03 2024-04-10 Palatin Technologies, Inc. Reverse amide-linked melanocortin receptor-specific cyclic peptides

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Publication number Publication date
AU2009257631A1 (en) 2009-12-17
MX2010013436A (es) 2011-06-21
KR101687037B1 (ko) 2016-12-15
ZA201009165B (en) 2012-03-28
NZ590254A (en) 2012-07-27
US8487073B2 (en) 2013-07-16
EP2300036B1 (en) 2017-04-05
IL209867A (en) 2015-08-31
JP2011522839A (ja) 2011-08-04
EA018630B1 (ru) 2013-09-30
US20110065652A1 (en) 2011-03-17
US8729224B2 (en) 2014-05-20
IL209867A0 (en) 2011-02-28
EA201001722A1 (ru) 2011-08-30
CN102131514A (zh) 2011-07-20
CA2727317C (en) 2015-02-17
EP2300036A4 (en) 2012-01-18
BRPI0909947A2 (pt) 2017-06-27
CA2727317A1 (en) 2009-12-17
US20130288987A1 (en) 2013-10-31
CN102131514B (zh) 2014-08-20
AU2009257631B2 (en) 2014-07-24
KR20110040819A (ko) 2011-04-20
EP2300036A1 (en) 2011-03-30
WO2009152079A1 (en) 2009-12-17

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