JP5624050B2 - 薬剤の送達装置及び方法 - Google Patents
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Description
この出願は2008年11月7日付にて提出された米国暫定特許出願第61/112,463号、発明の名称「薬剤の送達装置及び方法」に基づく優先権を主張するものであり、そこで開示された内容は全体が本件出願に包含される。
本発明は一般的に、患者に薬剤を送達するためのシステム及び方法に関する。とりわけ本発明の実施例は、治療薬の皮下注射用のシステム及び方法であり、注射した薬剤の効果を高める一又はそれ以上の治療源を使用するシステム及び方法に関する。
・EPROMチップなど、使い捨て部分を識別する独自の数字を有するシリアルナンバー;
・使い捨て部分を独自に識別するRFIDチップ;
・使い捨て部分を独自に識別する光学バーコード;
・1回だけ使用できる(例えば、取り外すと自己破壊するような)使い捨て部分に取り付ける再使用部分側の機械的アタッチメント;及び
・予め設定された制限された使用回数に充分なエネルギーを有する、再使用部分のバッテリー;
を具える。上記の例は、電気的エレメント(使い捨てではない)を変更し、交換前に使用できる回数を制限する非限定的実施例を説明している。当業者であれば分かるように、使用を制限する他の方法を用いることもできる。
Claims (17)
- 治療デバイスにおいて:
組織に複数の薬剤注射を実施するのに用いられる注射部位を有する治療エレメントであって、各注射が、所定の時間に前記組織の所定の位置に実行される治療エレメントと;
前記治療エレメント内に設けたプロセッサーと;
前記治療エレメント内部あるいは近傍に設けられており、前記プロセッサーによってコントロールされ、当該プロセッサーに電気的に接続されており、前記薬剤の注射前、注射中、及び注射後の少なくとも一つの間に所定の時間、所定の位置において前記組織を、前記組織が所定の制限温度より低い所定の温度に加温されるように構成された加温エレメントと;
前記プロセッサーに電気的に接続されており、前記加温エレメントによって加温された前記組織の温度に対応した信号を発するように構成された温度センサーと;
を具え、
前記組織の温度に基づいて、前記プロセッサが前記所定の温度への前記組織の加温を安定させるように構成されており、
前記加温エレメントによる加温が、前記薬剤の薬物動態上の特性及び/又は薬力学的な特性を改善するように構成されており、
前記治療エレメントが、使い捨て部分と再使用部分とを具えており、
前記使い捨て部分は、当該使い捨て部分が使用されたかどうかを判定するように構成された少なくとも一の識別エレメントを具えており、
前記治療エレメントが、前記薬剤の注射を検知し、当該検知に基づいて、前記加温エレメントを始動させるための信号を生成するように構成されたセンサーを具えることを特徴とするデバイス。 - 請求項1に記載のデバイスにおいて、前記再使用部分が:
前記プロセッサーと;
前記プロセッサーに接続されており、少なくとも1回加温するエネルギーを前記デバイスに提供するように構成されたエネルギー源と;
温度センサーと;
を具えることを特徴とするデバイス。 - 請求項2に記載のデバイスにおいて、前記温度センサーが、所定の部位を囲っている加温した組織と、加温エレメントのうちの少なくとも一つと温度伝達するように構成されていることを特徴とするデバイス。
- 請求項1に記載のデバイスにおいて、前記少なくとも一の識別エレメントが、電気的に溶断するエレメントと、EPROMチップのようなシリアルナンバーと、RFIDチップと、光学式バーコードと、1回だけ使用できる機械的アタッチメントとの少なくとも一つを具えていることを特徴とするデバイス。
- 請求項1に記載のデバイスにおいて、前記治療エレメントが、前記複数の注射のうちの少なくとも一の注射の場所を表示するように構成された少なくとも一の注射部位マーカーを具えることを特徴とするデバイス。
- 請求項1に記載のデバイスにおいて、前記治療エレメントが、前記薬剤が注射される時刻を認識するように構成された認識メカニズムを具え;
前記認識メカニズムによって提供される情報に基づいて、前記加温エレメントが自動的に加温を行うように構成されている、ことを特徴とするデバイス。 - 請求項1に記載のデバイスにおいて、前記治療エレメントが、前記組織の所定の位置を識別するように構成された識別メカニズムを具え;
前記識別メカニズムによって提供される情報に基づいて、前記加温エレメントが所定の熱プロフィールを適用するように構成されている、ことを特徴とするデバイス。 - 請求項7に記載のデバイスにおいて、前記所定の位置が、少なくとも一の食事のタイプ、あるいは少なくとも一の薬剤投与に対応していることを特徴とするデバイス。
- 請求項1に記載のデバイスにおいて、前記治療エレメントが特定の注射部位が使用されたことを表示するように構成されたインジケーターを具えることを特徴とするデバイス。
- 請求項1に記載のデバイスにおいて、前記加温エレメントが、前記組織上の所定の位置近傍に、前記組織上の前記所定の位置を部分的に取り囲んで、及び前記組織上の前記所定の位置を全部取り囲んで、の少なくとも一のやり方で配置されるように構成されていることを特徴とするデバイス。
- 請求項6に記載のデバイスにおいて、前記認識メカニズムが、皮膚の摘みを感知するように構成されたセンサーと、前記加温エレメントに配置された圧力センサーと、注射している間に指を置く地点をマーキングするように構成されたマーカーに配置された圧力センサーと、前記組織に薬剤を注射するデバイスの接近を感知するように構成された近接センサーと、の少なくとも一つを具えることを特徴とするデバイス。
- 請求項11に記載のデバイスにおいて、前記組織に薬剤注射するデバイスが、注射器と、ペン型インジェクターと、の少なくとも一つを具えていることを特徴とするデバイス。
- 請求項1に記載のデバイスにおいて、前記注射薬剤がインスリンであることを特徴とするデバイス。
- 請求項1に記載のデバイスにおいて、当該治療デバイスが、前記注射される薬剤の投与量とタイプに応じた少なくとも一の所定の治療プロフィールを具えていることを特徴とするデバイス。
- 請求項14に記載のデバイスにおいて、当該治療デバイスが、組織デポットに蓄えられている注射された薬剤のボリュームを計測するように構成され、更に当該計測したボリュームに基づいて加温を調整するように構成されたメカニズムを具えていることを特徴とするデバイス。
- 請求項15に記載のデバイスにおいて、前記ボリュームの計測を電気インピーダンス測定法を用いて行うことを特徴とするデバイス。
- 請求項1に記載のデバイスにおいて、前記治療デバイスが、次回の注射時刻に対応する警報を発するように構成されたメカニズムを具えることを特徴とするデバイス。
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Application Number | Priority Date | Filing Date | Title |
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US11246308P | 2008-11-07 | 2008-11-07 | |
US61/112,463 | 2008-11-07 | ||
PCT/IB2009/007600 WO2010052579A2 (en) | 2008-11-07 | 2009-11-06 | Device and method for drug delivery |
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JP2014194794A Division JP2015013210A (ja) | 2008-11-07 | 2014-09-25 | 薬剤の送達装置及び方法 |
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JP2014194794A Pending JP2015013210A (ja) | 2008-11-07 | 2014-09-25 | 薬剤の送達装置及び方法 |
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US20150265780A1 (en) | 2015-09-24 |
MX2011004817A (es) | 2011-07-28 |
BRPI0916125A2 (pt) | 2015-11-03 |
KR20110086132A (ko) | 2011-07-27 |
WO2010052579A2 (en) | 2010-05-14 |
CA2743027C (en) | 2016-04-12 |
CA2743027A1 (en) | 2010-05-14 |
JP2015013210A (ja) | 2015-01-22 |
IL212767A0 (en) | 2011-07-31 |
JP2012508052A (ja) | 2012-04-05 |
EP2355758A2 (en) | 2011-08-17 |
AU2009312474A1 (en) | 2010-05-14 |
CN102245137A (zh) | 2011-11-16 |
AU2009312474B2 (en) | 2014-12-04 |
WO2010052579A3 (en) | 2010-11-25 |
RU2011120820A (ru) | 2012-12-20 |
RU2014135706A (ru) | 2016-03-27 |
US9731084B2 (en) | 2017-08-15 |
RU2532893C2 (ru) | 2014-11-10 |
IL212767A (en) | 2015-08-31 |
US8961458B2 (en) | 2015-02-24 |
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