JP5592882B2 - ポリイソブチレンウレタン、尿素およびウレタン/尿素コポリマーならびにこれを含む医療機器 - Google Patents

ポリイソブチレンウレタン、尿素およびウレタン/尿素コポリマーならびにこれを含む医療機器 Download PDF

Info

Publication number
JP5592882B2
JP5592882B2 JP2011516708A JP2011516708A JP5592882B2 JP 5592882 B2 JP5592882 B2 JP 5592882B2 JP 2011516708 A JP2011516708 A JP 2011516708A JP 2011516708 A JP2011516708 A JP 2011516708A JP 5592882 B2 JP5592882 B2 JP 5592882B2
Authority
JP
Japan
Prior art keywords
diol
polyisobutylene
urethane
urea
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2011516708A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011526326A (ja
JP2011526326A5 (OSRAM
Inventor
デサイ、シュロジャルクマール
シー. シュワルツ、マレーネ
ボーデン、マーク
クリシュナン、モーハン
シー. スミス、マイケル
エイチ. ストリクラー、フレデリック
ジェイ. クック、ダニエル
Original Assignee
カーディアック ペースメイカーズ, インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by カーディアック ペースメイカーズ, インコーポレイテッド filed Critical カーディアック ペースメイカーズ, インコーポレイテッド
Publication of JP2011526326A publication Critical patent/JP2011526326A/ja
Publication of JP2011526326A5 publication Critical patent/JP2011526326A5/ja
Application granted granted Critical
Publication of JP5592882B2 publication Critical patent/JP5592882B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40High-molecular-weight compounds
    • C08G18/62Polymers of compounds having carbon-to-carbon double bonds
    • C08G18/6204Polymers of olefins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/18Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/06Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08Processes
    • C08G18/10Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08Processes
    • C08G18/10Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
    • C08G18/12Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step using two or more compounds having active hydrogen in the first polymerisation step
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40High-molecular-weight compounds
    • C08G18/4009Two or more macromolecular compounds not provided for in one single group of groups C08G18/42 - C08G18/64
    • C08G18/4063Mixtures of compounds of group C08G18/62 with other macromolecular compounds
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40High-molecular-weight compounds
    • C08G18/48Polyethers
    • C08G18/4854Polyethers containing oxyalkylene groups having four carbon atoms in the alkylene group
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40High-molecular-weight compounds
    • C08G18/48Polyethers
    • C08G18/4858Polyethers containing oxyalkylene groups having more than four carbon atoms in the alkylene group
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/65Low-molecular-weight compounds having active hydrogen with high-molecular-weight compounds having active hydrogen
    • C08G18/6505Low-molecular-weight compounds having active hydrogen with high-molecular-weight compounds having active hydrogen the low-molecular compounds being compounds of group C08G18/32 or polyamines of C08G18/38
    • C08G18/6511Low-molecular-weight compounds having active hydrogen with high-molecular-weight compounds having active hydrogen the low-molecular compounds being compounds of group C08G18/32 or polyamines of C08G18/38 compounds of group C08G18/3203
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/72Polyisocyanates or polyisothiocyanates
    • C08G18/74Polyisocyanates or polyisothiocyanates cyclic
    • C08G18/76Polyisocyanates or polyisothiocyanates cyclic aromatic
    • C08G18/7657Polyisocyanates or polyisothiocyanates cyclic aromatic containing two or more aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Materials For Medical Uses (AREA)
JP2011516708A 2008-06-27 2009-06-26 ポリイソブチレンウレタン、尿素およびウレタン/尿素コポリマーならびにこれを含む医療機器 Active JP5592882B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7632708P 2008-06-27 2008-06-27
US61/076,327 2008-06-27
PCT/US2009/048827 WO2009158600A1 (en) 2008-06-27 2009-06-26 Polyisobutylene urethane, urea and urethane/urea copolymers and medical devices containing the same

Publications (3)

Publication Number Publication Date
JP2011526326A JP2011526326A (ja) 2011-10-06
JP2011526326A5 JP2011526326A5 (OSRAM) 2012-08-16
JP5592882B2 true JP5592882B2 (ja) 2014-09-17

Family

ID=41077669

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011516708A Active JP5592882B2 (ja) 2008-06-27 2009-06-26 ポリイソブチレンウレタン、尿素およびウレタン/尿素コポリマーならびにこれを含む医療機器

Country Status (6)

Country Link
US (3) US20090326077A1 (OSRAM)
EP (1) EP2291204A1 (OSRAM)
JP (1) JP5592882B2 (OSRAM)
CN (1) CN102131530A (OSRAM)
AU (1) AU2009262097B2 (OSRAM)
WO (2) WO2009158600A1 (OSRAM)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7715922B1 (en) * 2005-11-16 2010-05-11 Pacesetter, Inc. Polyethylene oxide and polyisobutylene copolymers and their usage on medical devices
WO2007139199A1 (ja) * 2006-05-31 2007-12-06 Kaneka Corporation カテーテル用チューブ及びそれからなるカテーテル
WO2009158600A1 (en) * 2008-06-27 2009-12-30 Cardiac Pacemakers, Inc. Polyisobutylene urethane, urea and urethane/urea copolymers and medical devices containing the same
US20110213084A1 (en) * 2008-10-01 2011-09-01 The University Of Akron Polymers having both hard and soft segments, and process for making same
JP5775822B2 (ja) 2008-12-31 2015-09-09 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. ポリイソブチレンおよび生分解性ポリマーセグメントを持つコポリマー
EP3670561B1 (en) * 2009-01-12 2023-12-06 University Of Massachusetts Lowell Polyisobutylene-based polyurethanes
CN102573940B (zh) 2009-08-21 2015-04-01 心脏起搏器公司 可交联聚异丁烯类聚合物及包含其的医疗装置
US8374704B2 (en) * 2009-09-02 2013-02-12 Cardiac Pacemakers, Inc. Polyisobutylene urethane, urea and urethane/urea copolymers and medical leads containing the same
US8644952B2 (en) 2009-09-02 2014-02-04 Cardiac Pacemakers, Inc. Medical devices including polyisobutylene based polymers and derivatives thereof
US8674034B2 (en) * 2009-11-11 2014-03-18 The University Of Akron Polyisobutylene-based polyurethanes, polyureas and/or polyurethane-polyureas and method for making same
US20110152989A1 (en) * 2009-12-23 2011-06-23 Pacesetter, Inc. Soft abrasion-resistant polyisobutylene urethane copolymers
US8660663B2 (en) 2010-12-20 2014-02-25 Cardiac Pacemakers, Inc. Lead having a conductive polymer conductor
US20130041108A1 (en) * 2011-05-19 2013-02-14 Joseph P. Kennedy Polymers having both hard and soft segments, and process for making same
AU2012295332B2 (en) 2011-08-12 2014-12-04 Cardiac Pacemakers, Inc. Method for coating devices using electrospinning and melt blowing
US10285793B2 (en) * 2012-02-08 2019-05-14 Boston Scientific Scimed, Inc. Surgical scaffolds
WO2013151656A1 (en) 2012-04-02 2013-10-10 Medtronic, Inc. Medical leads
WO2014008207A1 (en) * 2012-07-02 2014-01-09 Boston Scientific Scimed, Inc. Prosthetic heart valve formation
IN2015DN00393A (OSRAM) * 2012-07-23 2015-06-19 Univ Akron
JP6148339B2 (ja) * 2012-09-11 2017-06-14 カーディアック ペースメイカーズ, インコーポレイテッド 植込み型医用電気リード線及びその製造方法
US9926399B2 (en) 2012-11-21 2018-03-27 University Of Massachusetts High strength polyisobutylene polyurethanes
US10343385B2 (en) 2013-07-18 2019-07-09 Boston Scientific Scimed, Inc. Bodily implant
US20150025608A1 (en) 2013-07-22 2015-01-22 Cardiac Pacemakers, Inc. Lubricious, biocompatible hydrophilic thermoset coating using interpenetrating hydrogel networks
WO2015053934A1 (en) 2013-10-10 2015-04-16 Medtronic, Inc. Implantable medical devices including a polyether-polyurethane substrate with improved biostability, and methods
WO2016068934A1 (en) * 2014-10-30 2016-05-06 Cardiac Pacemakers, Inc. Solvent free polyisobutylene based polyurethanes
US10314696B2 (en) 2015-04-09 2019-06-11 Boston Scientific Scimed, Inc. Prosthetic heart valves having fiber reinforced leaflets
US10426609B2 (en) 2015-04-09 2019-10-01 Boston Scientific Scimed, Inc. Fiber reinforced prosthetic heart valve having undulating fibers
US10299915B2 (en) 2015-04-09 2019-05-28 Boston Scientific Scimed, Inc. Synthetic heart valves composed of zwitterionic polymers
EP3286251B1 (en) * 2015-04-23 2019-02-20 Cardiac Pacemakers, Inc. Compositions and methods for copolymer solutions with high weight percent copolymers
US10716671B2 (en) 2015-07-02 2020-07-21 Boston Scientific Scimed, Inc. Prosthetic heart valve composed of composite fibers
US10413403B2 (en) 2015-07-14 2019-09-17 Boston Scientific Scimed, Inc. Prosthetic heart valve including self-reinforced composite leaflets
EP3325084B1 (en) 2015-07-25 2019-08-21 Cardiac Pacemakers, Inc. Medical electrical lead with biostable pvdf-based materials
US10195023B2 (en) 2015-09-15 2019-02-05 Boston Scientific Scimed, Inc. Prosthetic heart valves including pre-stressed fibers
CN119081064A (zh) * 2015-10-17 2024-12-06 心脏起搏器股份公司 原位可交联聚异丁烯-聚氨酯纳米纤维和涂层的生产
US20170327622A1 (en) * 2016-05-10 2017-11-16 Cardiac Pacemakers, Inc. Thermoset polyisobutylene-polyurethanes and methods for making
EP3457989B1 (en) 2016-05-19 2021-09-29 Boston Scientific Scimed, Inc. Prosthetic valves, valve leaflets and related methods
WO2018125864A1 (en) 2016-12-27 2018-07-05 Boston Scientific Scimed Inc. Degradable scaffolding for electrospinning
WO2018165273A1 (en) 2017-03-07 2018-09-13 Cardiac Pacemakers, Inc. Hydroboration/oxidation of allyl-terminated polyisobutylene
CN110494170A (zh) 2017-04-25 2019-11-22 波士顿科学国际有限公司 生物相容性聚异丁烯-纤维复合材料和方法
KR102282617B1 (ko) * 2017-05-15 2021-07-28 다이너파워 컴퍼니 엘엘씨 태양광 에너지용 에너지 저장 시스템 및 태양광 에너지 저장 방법
EP3668912B1 (en) 2017-08-17 2021-06-30 Cardiac Pacemakers, Inc. Photocrosslinked polymers for enhanced durability
EP3740253B1 (en) * 2018-01-17 2023-08-16 Cardiac Pacemakers, Inc. End-capped polyisobutylene polyurethane
US10882945B2 (en) 2018-03-26 2021-01-05 Medtronic, Inc. Modified polyisobutylene-based polymers, methods of making, and medical devices
US20190292327A1 (en) * 2018-03-26 2019-09-26 Medtronic, Inc. Poly(ether-carbonate)-based polymers and medical devices
US10899869B2 (en) 2019-01-24 2021-01-26 The University Of Akron Glycerol containing polyurethanes and polyurethane nanocomposites
US12245935B2 (en) 2019-11-26 2025-03-11 Boston Scientific Limited Composite web-polymer heart valve
CN116057101A (zh) * 2020-08-06 2023-05-02 阿克伦大学 高分子量和强度的基于聚异丁烯的聚氨酯的合成及其用途
CN112831013B (zh) * 2021-02-25 2022-03-29 中国科学院长春应用化学研究所 一种功能化聚氨酯及其制备方法和应用

Family Cites Families (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3328372A (en) * 1964-05-11 1967-06-27 Exxon Research Engineering Co Soluble high molecular weight polymers of cyclopentadiene
NL6606553A (OSRAM) * 1965-06-18 1967-11-13
BE759829A (fr) * 1969-12-03 1971-06-03 Upjohn Co Preparation de polyurethanes
GB1527592A (en) * 1974-08-05 1978-10-04 Ici Ltd Wound dressing
GB1542319A (en) * 1975-11-26 1979-03-14 Exxon Research Engineering Co Halogenated organoaluminium catalyst compositions and method of their preparation
US4316973A (en) * 1979-09-10 1982-02-23 The University Of Akron Novel telechelic polymers and processes for the preparation thereof
US4276394A (en) 1979-09-10 1981-06-30 The University Of Akron Novel telechelic polymers, block copolymers and processes for the preparation thereof
US4342849A (en) * 1979-09-10 1982-08-03 The University Of Akron Novel telechelic polymers and processes for the preparation thereof
US4675361A (en) * 1980-02-29 1987-06-23 Thoratec Laboratories Corp. Polymer systems suitable for blood-contacting surfaces of a biomedical device, and methods for forming
US4686137A (en) * 1980-02-29 1987-08-11 Thoratec Laboratories Corp. Moisture vapor permeable materials
US4861830A (en) * 1980-02-29 1989-08-29 Th. Goldschmidt Ag Polymer systems suitable for blood-contacting surfaces of a biomedical device, and methods for forming
US5120813A (en) * 1980-02-29 1992-06-09 Th. Goldschmidt Ag Moisture vapor permeable materials
US4423185A (en) * 1980-03-03 1983-12-27 Asahi Kasei Kogyo Kabushiki Kaisha Thermoplastic resinous composition
US4570270A (en) * 1982-09-20 1986-02-18 Oechsle Iii Sixtus J Polyurethane compositions and their use as luting agents
US4477604A (en) * 1982-09-20 1984-10-16 Oechsle Iii Sixtus J Polyurethane compositions and their use as luting agents
US4486572A (en) * 1983-07-06 1984-12-04 University Of Akron Synthesis of amphiphilic block copolymers and networks
US4767885A (en) * 1984-08-06 1988-08-30 University Of Akron Sterically hindered binifers telechelic polymers made therefrom
US4888389A (en) * 1985-02-05 1989-12-19 University Of Akron Amphiphilic polymers and method of making said polymers
US4910321A (en) 1985-06-20 1990-03-20 University Of Akron Living catalysts, complexes and polymers therefrom
JPH02501031A (ja) * 1986-01-30 1990-04-12 フセソユーズヌイ、ナウチノーイスレドワーチェルスキー、イ、イスピタテルヌイ、インスチツート、メディツィンスコイ、チェフニキ 外傷学上の固定用ポリウレタンフォーム組成物
US4880883A (en) 1987-06-03 1989-11-14 Wisconsin Alumni Research Foundation Biocompatible polyurethanes modified with lower alkyl sulfonate and lower alkyl carboxylate
US5017664A (en) * 1987-06-03 1991-05-21 Wisconsin Alumni Research Foundation Biocompatible polyurethane devices wherein polyurethane is modified with lower alkyl sulfonate and lower alkyl carboxylate
EP0295640B1 (en) * 1987-06-18 1993-02-03 Dai-Ichi Kogyo Seiyaku Co., Ltd. Polyurethane composition
US4752626A (en) * 1987-08-27 1988-06-21 General Motors Corporation Method of making low compression set urethane foams
US5149739A (en) * 1988-08-01 1992-09-22 The Bfgoodrich Company Fiber-reinforced thermoplastic elastomer polyurethane compositions with either modified and/or unmodified polyolefins
US4939184A (en) 1989-03-07 1990-07-03 University Of Akron Polyurethane foam
US5194505A (en) * 1989-09-29 1993-03-16 E. I. Du Pont De Nemours And Company Chlorosulfonated polyolefin-modified polyurethane and polyurea compositions and process for making same
BR9003841A (pt) 1990-08-06 1992-02-25 Sika S A Resina de poliuretana,adesivo,resina epoxi,processo para producao das ditas resinas,tinta e uso
DE59108551D1 (de) * 1990-08-16 1997-03-27 Basf Ag Verfahren zur Herstellung von Kohlenwasserstoffen und Polymeren mit allylischen Chloridendgruppen
US6010715A (en) * 1992-04-01 2000-01-04 Bertek, Inc. Transdermal patch incorporating a polymer film incorporated with an active agent
US5589563A (en) * 1992-04-24 1996-12-31 The Polymer Technology Group Surface-modifying endgroups for biomedical polymers
DE69320470T2 (de) * 1992-04-24 1999-04-29 The Polymer Technology Group, Inc., Emeryville, Calif. Copolymere, sowie daraus hergestellte nichtporöse halbdurchlässige membranen und ihre verwendung zum filtern von molekülen in einem vorgegebenen molekulargewichtbereich
US5340881A (en) * 1992-11-16 1994-08-23 The University Of Akron Aldehyde-telechelic polyisobutylenes, catalytic method for preparing the same with high conversion and selectivity, and block copolymers made thereform
DE4303556C1 (de) 1993-02-08 1994-10-27 Bayer Ag Harte Polyurethane oder Polyurethanschaumstoffe
GB9306887D0 (en) 1993-04-01 1993-05-26 Graham Neil B Random block copolymers
WO1995010544A1 (en) * 1993-10-15 1995-04-20 University Of Massachusetts At Lowell Capping of living polymers
US5442010A (en) * 1994-10-04 1995-08-15 Dow Corning Corporation Epoxy-terminated polyisobutylene-polydimethylsiloxane compositions
CA2168938C (en) * 1995-03-13 2010-06-01 Wolfgang Kaufhold A thermoplastic polyurethane resin
US5663234A (en) 1995-06-15 1997-09-02 The University Of Akron Cationic multiblock thermoplastic elastomers
DE19610350A1 (de) 1996-03-15 1997-09-18 Basf Ag Initiatoren für die anionisch initiierte Polymerisation von wenigstens eine ethylenisch ungesättigte Gruppe aufweisenden Monomeren
US5912302A (en) * 1996-06-11 1999-06-15 Gadkari; Avinash Chandrakant Elastomeric compositions and a process to produce elastomeric compositions
US5741331A (en) * 1996-07-29 1998-04-21 Corvita Corporation Biostable elastomeric polymers having quaternary carbons
US6200589B1 (en) * 1996-09-13 2001-03-13 The University Of Akron Biological implants of semipermeable amphiphilic membranes
AUPO251096A0 (en) * 1996-09-23 1996-10-17 Cardiac Crc Nominees Pty Limited Polysiloxane-containing polyurethane elastomeric compositions
ES2136927T3 (es) 1996-10-15 1999-12-01 Advanced Elastomer Systems Nuevos copolimeros de bloques de poliolefinas con poliuretanos, copoliesteres o copoliamidas y su uso.
JP2001509834A (ja) 1997-01-30 2001-07-24 シエル・インターナシヨナル・リサーチ・マートスハツペイ・ベー・ヴエー 硬質及び半硬質のポリウレタンフォーム中のポリオール混合物の使用
WO1998033832A1 (en) 1997-01-30 1998-08-06 Shell Internationale Research Maatschappij B.V. Use of polyol mixtures in rigid and semi-rigid polyurethane foams
US5874484A (en) * 1997-01-30 1999-02-23 Shell Oil Company Use of polyol mixtures in rigid and semi-rigid polyurethane foams
US6005051A (en) * 1997-08-06 1999-12-21 The University Of Akron Multi-component polymeric networks containing polyisobutylene
US6072003A (en) * 1997-08-25 2000-06-06 Advanced Elastomer Systems, L.P. Block copolymers of polyolefins with polyurethanes, copolyesters or copolyamides and their use
JP3671624B2 (ja) * 1997-10-27 2005-07-13 株式会社カネカ ポリウレタン系弾性繊維
US6093197A (en) * 1997-12-08 2000-07-25 Axon Engineering, Inc. Spiral nerve cuff electrode implantation tool
CN1075103C (zh) 1998-09-21 2001-11-21 深圳市奥博胶粘剂化工有限公司 一种聚氨酯粘接剂/密封胶组合物及其制备方法
EP1061092A1 (en) 1999-06-17 2000-12-20 Shell Internationale Researchmaatschappij B.V. Process for the preparation of a rigid polyurethane foam.
US6228945B1 (en) * 1999-12-20 2001-05-08 The University Of Akron Three arm star compositions of matter having diblock arms based on polyisobutylene and methods of preparation
US6555619B1 (en) 2000-06-29 2003-04-29 The University Of Akron Physically crosslinked amphiphilic networks, methods of preparation, and uses thereof
WO2002032986A1 (en) * 2000-10-18 2002-04-25 Mitsui Chemicals, Inc. Foam of thermoplastic urethane elastomer composition and process for producing the foam
TW541853B (en) * 2000-11-10 2003-07-11 Sumitomo Chemical Co Polymeric fluorescent substance and polymer light-emitting device using the same
US6545097B2 (en) 2000-12-12 2003-04-08 Scimed Life Systems, Inc. Drug delivery compositions and medical devices containing block copolymer
US7396582B2 (en) * 2001-04-06 2008-07-08 Advanced Cardiovascular Systems, Inc. Medical device chemically modified by plasma polymerization
US6600956B2 (en) * 2001-08-21 2003-07-29 Cyberonics, Inc. Circumneural electrode assembly
WO2003042273A1 (en) 2001-11-14 2003-05-22 Medtronic, Inc. Compounds containing quaternary carbons, medical devices, and methods
EP1446437B1 (en) 2001-11-14 2015-04-15 Medtronic, Inc. Compounds containing quaternary carbons, medical devices, and methods
US7196142B2 (en) * 2002-04-04 2007-03-27 The University Of Akron Polyisobutylene-based block anionomers and cationomers and synthesis thereof
US7292890B2 (en) * 2002-06-20 2007-11-06 Advanced Bionics Corporation Vagus nerve stimulation via unidirectional propagation of action potentials
US20040039437A1 (en) 2002-08-13 2004-02-26 Medtronic, Inc. Medical device exhibiting improved adhesion between polymeric coating and substrate
DE10241853B3 (de) * 2002-09-09 2004-01-22 Byk-Chemie Gmbh Polymeres Harnstoffurethan als Rheologiesteuerungsmittel und Verfahren zur Herstellung
DE60323243D1 (de) * 2002-09-17 2008-10-09 Medtronic Inc Verbindungen die quarternäre kohlstoffe und siliziumgruppen enthalten, medizinsiche geräte und verfahren
EP1567559A4 (en) * 2002-11-12 2008-04-16 Polymer Technology Group Inc REGULATION OF MOLECULAR POLYMER SURFACE ARCHITECTURE USING AMPHIPATHIC TERMINAL GROUPS
GB0311121D0 (en) * 2003-05-15 2003-06-18 Avecia Ltd Polyurethane dispersants
US20050060022A1 (en) * 2003-05-21 2005-03-17 Felt Jeffrey C. Polymer stent
US6969744B2 (en) 2003-06-19 2005-11-29 University Of Southern Mississippi Living and quasiliving cationic telechelic polymers quenched by N-substituted pyrrole and methods for their preparation
WO2004113400A2 (en) 2003-06-20 2004-12-29 Scimed Life Systems, Inc. End-cappped polymer chains and products thereof
US20070093604A1 (en) * 2003-07-01 2007-04-26 Joseph Kennedy Thermoplastic elastomeric multiblock copolymers of isobutylene and norbornene
US7056985B2 (en) * 2004-02-11 2006-06-06 University Of Massachusetts Lowell End-capped polymer chains and products thereof
US7105622B2 (en) * 2004-06-02 2006-09-12 The University Of Akron Hybrid polyurethanes
US20050288476A1 (en) * 2004-06-17 2005-12-29 Iskender Yilgor Thermoplastic copolymers through stoichiometric reactions between diisocyanates and oligomeric diols and diamines
JP2006274235A (ja) 2004-07-30 2006-10-12 Fuji Photo Film Co Ltd 重合性組成物、光学異方性層及びその製造方法、光学補償素子、液晶表示装置及び液晶プロジェクタ
US20060047083A1 (en) * 2004-08-30 2006-03-02 Iskender Yilgor Triblock copolymers and their production methods
US7347751B2 (en) * 2004-09-30 2008-03-25 Cardiac Pacemakers, Inc. Cardiac lead implantation system
US20060264577A1 (en) * 2005-04-08 2006-11-23 Rudolf Faust Capping reactions in cationic polymerization; kinetic and synthetic utility
US20070051531A1 (en) * 2005-09-08 2007-03-08 Harshad Borgaonkar Drug eluting coatings for a medical lead and method therefor
US7715922B1 (en) * 2005-11-16 2010-05-11 Pacesetter, Inc. Polyethylene oxide and polyisobutylene copolymers and their usage on medical devices
US7553546B1 (en) 2005-11-16 2009-06-30 Pacesetter, Inc. Polyethylene oxide and silicone copolymers and their usage on medical devices
EP2001473A4 (en) 2006-03-31 2012-12-26 Advanced Neuromodulation Sys SUBSEQUENT ELECTROSTIMULATION PIPES AND METHOD OF MANUFACTURING THEM
EP2004715A2 (en) 2006-04-07 2008-12-24 University Of Massachusetts Lowell Method to prepare block copolymers by the combination of cationic and anionic polymerization
WO2007139199A1 (ja) 2006-05-31 2007-12-06 Kaneka Corporation カテーテル用チューブ及びそれからなるカテーテル
US20100069578A1 (en) * 2006-11-17 2010-03-18 Rudolf Faust Functional Hydrocarbon Polymers and Process for Producing Same
EP2099831B1 (en) 2006-11-30 2019-07-31 The University of Akron Polyisobutylenes and process for making same
CN101686854B (zh) 2007-03-09 2012-11-28 阿克伦大学 生物人工胰及其制备方法
WO2008114855A1 (ja) * 2007-03-16 2008-09-25 Ube Industries, Ltd. 酸化亜鉛単結晶の製造方法
JP2008238761A (ja) 2007-03-29 2008-10-09 Toyoda Gosei Co Ltd ポリウレタン材料及びその製造方法
US8431666B2 (en) 2007-04-12 2013-04-30 The University Of Akron Injectible cyanoacrylate-functionalized polyisobutylenes
US8569420B2 (en) 2007-06-19 2013-10-29 The University Of Akron Singly-terminated polyisobutylenes and process for making same
EP2207824A4 (en) 2007-11-01 2011-02-16 Univ Akron THERMOPLASTIC AMPHIPHILIC CO-NETWORKS
WO2009158600A1 (en) 2008-06-27 2009-12-30 Cardiac Pacemakers, Inc. Polyisobutylene urethane, urea and urethane/urea copolymers and medical devices containing the same
WO2010033359A1 (en) * 2008-09-19 2010-03-25 Cardiac Pacemakers, Inc. Surface modification to improve lubricity, abrasion resistance and temperature resilience of leads
US20110213084A1 (en) 2008-10-01 2011-09-01 The University Of Akron Polymers having both hard and soft segments, and process for making same
EP3670561B1 (en) * 2009-01-12 2023-12-06 University Of Massachusetts Lowell Polyisobutylene-based polyurethanes
US8155759B2 (en) * 2009-03-20 2012-04-10 Innovia, Llc Pacemaker lead and method of making same
US20120077934A1 (en) * 2009-03-23 2012-03-29 University Of Massachusetts Functional Polyisobutylene Based Macromonomers And Methods For Making And Using The Same
CN102573940B (zh) 2009-08-21 2015-04-01 心脏起搏器公司 可交联聚异丁烯类聚合物及包含其的医疗装置
US8374704B2 (en) * 2009-09-02 2013-02-12 Cardiac Pacemakers, Inc. Polyisobutylene urethane, urea and urethane/urea copolymers and medical leads containing the same
US8644952B2 (en) * 2009-09-02 2014-02-04 Cardiac Pacemakers, Inc. Medical devices including polyisobutylene based polymers and derivatives thereof
US8674034B2 (en) 2009-11-11 2014-03-18 The University Of Akron Polyisobutylene-based polyurethanes, polyureas and/or polyurethane-polyureas and method for making same

Also Published As

Publication number Publication date
WO2009158609A1 (en) 2009-12-30
US8324290B2 (en) 2012-12-04
JP2011526326A (ja) 2011-10-06
EP2291204A1 (en) 2011-03-09
CN102131530A (zh) 2011-07-20
US8501831B2 (en) 2013-08-06
US20090326077A1 (en) 2009-12-31
AU2009262097B2 (en) 2014-03-20
WO2009158600A1 (en) 2009-12-30
US20130013040A1 (en) 2013-01-10
US20100023104A1 (en) 2010-01-28
AU2009262097A1 (en) 2009-12-30

Similar Documents

Publication Publication Date Title
JP5592882B2 (ja) ポリイソブチレンウレタン、尿素およびウレタン/尿素コポリマーならびにこれを含む医療機器
US8927660B2 (en) Crosslinkable polyisobutylene-based polymers and medical devices containing the same
EP2373356B1 (en) Copolymers having polyisobutylene and biodegradable polymer segments
US8187623B2 (en) Medical copolymers
EP2237810B1 (en) Biodegradable polymers
US8202654B2 (en) Medical devices having fluorocarbon polymer coatings

Legal Events

Date Code Title Description
RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20120217

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120626

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20120626

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20130913

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20130924

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20131220

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20140106

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20140708

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20140801

R150 Certificate of patent or registration of utility model

Ref document number: 5592882

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250