JP5557982B2 - 天然ＩｇＭ抗体およびその阻害剤 - Google Patents

天然ＩｇＭ抗体およびその阻害剤 Download PDF

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Publication number
JP5557982B2
JP5557982B2 JP2007501869A JP2007501869A JP5557982B2 JP 5557982 B2 JP5557982 B2 JP 5557982B2 JP 2007501869 A JP2007501869 A JP 2007501869A JP 2007501869 A JP2007501869 A JP 2007501869A JP 5557982 B2 JP5557982 B2 JP 5557982B2
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Japan
Prior art keywords
peptide
igm
antibody
seq
cells
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Expired - Fee Related
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JP2007501869A
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English (en)
Japanese (ja)
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JP2008504807A (ja
Inventor
マイケル シー． キャロル
ジュニア フランシス ディー． ムーア
ハーバート ビー． ヘクトマン
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Brigham and Womens Hospital Inc
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Brigham and Womens Hospital Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2007501869A 2004-03-01 2005-03-01 天然ＩｇＭ抗体およびその阻害剤 Expired - Fee Related JP5557982B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US54912304P 2004-03-01 2004-03-01
US60/549,123 2004-03-01
US58864804P 2004-07-16 2004-07-16
US60/588,648 2004-07-16
PCT/US2005/006276 WO2005085288A2 (en) 2004-03-01 2005-03-01 Natural igm antibodies and inhibitors thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011019668A Division JP5618852B2 (ja) 2004-03-01 2011-02-01 天然ＩｇＭ抗体およびその阻害剤

Publications (2)

Publication Number Publication Date
JP2008504807A JP2008504807A (ja) 2008-02-21
JP5557982B2 true JP5557982B2 (ja) 2014-07-23

Family

ID=34922704

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2007501869A Expired - Fee Related JP5557982B2 (ja) 2004-03-01 2005-03-01 天然ＩｇＭ抗体およびその阻害剤
JP2011019668A Expired - Fee Related JP5618852B2 (ja) 2004-03-01 2011-02-01 天然ＩｇＭ抗体およびその阻害剤
JP2014089965A Pending JP2014155497A (ja) 2004-03-01 2014-04-24 天然ＩｇＭ抗体およびその阻害剤

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2011019668A Expired - Fee Related JP5618852B2 (ja) 2004-03-01 2011-02-01 天然ＩｇＭ抗体およびその阻害剤
JP2014089965A Pending JP2014155497A (ja) 2004-03-01 2014-04-24 天然ＩｇＭ抗体およびその阻害剤

Country Status (9)

Country Link
US (5) US7442783B2 (https=)
EP (2) EP2290077B1 (https=)
JP (3) JP5557982B2 (https=)
AT (1) ATE498010T1 (https=)
AU (1) AU2005219839B9 (https=)
CA (1) CA2560066A1 (https=)
DE (1) DE602005026260D1 (https=)
IL (1) IL177825A (https=)
WO (1) WO2005085288A2 (https=)

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* Cited by examiner, † Cited by third party
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US20100136684A1 (en) * 2004-03-01 2010-06-03 Carroll Michael C Natural IgM Antibodies
ATE498010T1 (de) 2004-03-01 2011-02-15 Immune Disease Inst Inc Natürliche igm-antikörper und inhibitoren davon
US8324352B2 (en) 2009-12-07 2012-12-04 Decimmune Therapeutics, Inc. Anti-inflammatory antibodies and uses therefor
KR20130108104A (ko) * 2010-06-03 2013-10-02 아브락시스 바이오사이언스, 엘엘씨 말초혈 ｓｐａｒｃ 결합 항체와 이들의 용도
WO2014055392A2 (en) * 2012-10-01 2014-04-10 Decimmune Therapeutics, Inc. Method of protecting cardiac function
JP6162319B2 (ja) 2013-03-12 2017-07-12 デシミューン セラピューティクス，インコーポレイテッド ヒト化抗ｎ２抗体
JP6551825B2 (ja) * 2014-02-10 2019-07-31 公立大学法人首都大学東京 クロマチン構造制御剤

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Also Published As

Publication number Publication date
WO2005085288A3 (en) 2006-08-03
IL177825A0 (en) 2006-12-31
CA2560066A1 (en) 2005-09-15
US7442783B2 (en) 2008-10-28
EP2290077B1 (en) 2016-01-27
US20050276811A1 (en) 2005-12-15
IL177825A (en) 2013-02-28
US20170342109A1 (en) 2017-11-30
EP1725659A2 (en) 2006-11-29
DE602005026260D1 (de) 2011-03-24
US20160280740A1 (en) 2016-09-29
EP1725659B1 (en) 2011-02-09
HK1154904A1 (en) 2012-05-04
ATE498010T1 (de) 2011-02-15
AU2005219839B9 (en) 2011-12-22
WO2005085288A2 (en) 2005-09-15
US9657060B2 (en) 2017-05-23
JP5618852B2 (ja) 2014-11-05
EP2290077A3 (en) 2011-05-18
US9914751B2 (en) 2018-03-13
US20090176966A1 (en) 2009-07-09
JP2008504807A (ja) 2008-02-21
JP2014155497A (ja) 2014-08-28
AU2005219839A1 (en) 2005-09-15
JP2011139704A (ja) 2011-07-21
US20140127214A1 (en) 2014-05-08
AU2005219839B2 (en) 2011-11-24
EP2290077A2 (en) 2011-03-02

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