JP5550907B2 - 治療組成物およびカプシアノシド型化合物による治療方法 - Google Patents

治療組成物およびカプシアノシド型化合物による治療方法 Download PDF

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JP5550907B2
JP5550907B2 JP2009534900A JP2009534900A JP5550907B2 JP 5550907 B2 JP5550907 B2 JP 5550907B2 JP 2009534900 A JP2009534900 A JP 2009534900A JP 2009534900 A JP2009534900 A JP 2009534900A JP 5550907 B2 JP5550907 B2 JP 5550907B2
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pharmaceutical composition
formula
compound
mammal
compounds
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JP2010508299A5 (enExample
JP2010508299A (ja
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ベルゴロド，バリー・マイルズ
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ビー・エム・ビー・パテント・ホールデイング・コーポレイシヨン
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/04—Disaccharides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
JP2009534900A 2006-10-27 2007-10-26 治療組成物およびカプシアノシド型化合物による治療方法 Active JP5550907B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US86330206P 2006-10-27 2006-10-27
US60/863,302 2006-10-27
PCT/US2007/082717 WO2008052183A2 (en) 2006-10-27 2007-10-26 Therapeutic compositions and methods of treatment with capsianoside-type compounds

Related Child Applications (1)

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JP2013228352A Division JP5551301B2 (ja) 2006-10-27 2013-11-01 治療組成物およびカプシアノシド型化合物による治療方法

Publications (3)

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JP2010508299A JP2010508299A (ja) 2010-03-18
JP2010508299A5 JP2010508299A5 (enExample) 2010-12-16
JP5550907B2 true JP5550907B2 (ja) 2014-07-16

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JP2009534900A Active JP5550907B2 (ja) 2006-10-27 2007-10-26 治療組成物およびカプシアノシド型化合物による治療方法
JP2013228352A Active JP5551301B2 (ja) 2006-10-27 2013-11-01 治療組成物およびカプシアノシド型化合物による治療方法

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Country Link
US (3) US20080103102A1 (enExample)
EP (1) EP2096927B1 (enExample)
JP (2) JP5550907B2 (enExample)
WO (1) WO2008052183A2 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080103102A1 (en) * 2006-10-27 2008-05-01 Bmb Patent Holding Corporation Therapeutic compositions and methods of treatment with capsianoside-type compounds
US20110200669A1 (en) * 2010-02-15 2011-08-18 Winston Laboratories, Inc. Method and compositions of civamide to treat disease of the intestines
KR101418239B1 (ko) * 2010-03-22 2014-07-14 한양대학교 산학협력단 파프리카 추출물을 함유하는 염증, 알레르기 또는 천식 질환 치료용 조성물
KR101244101B1 (ko) * 2010-10-08 2013-03-18 (주)미애부생명과학 파프리카 발효물을 유효 성분으로 포함하는 피부 염증 개선용 화장료 조성물
US9822257B2 (en) 2012-07-23 2017-11-21 Crayola Llc Dissolvable films and methods of using the same
CN104840691A (zh) * 2015-04-28 2015-08-19 姚美艳 一种治疗膝关节创伤性滑膜炎的中药制剂及护理方法
EP3888684A1 (en) * 2020-03-31 2021-10-06 Bayer Animal Health GmbH Composition having improved voluntary acceptance
WO2025090573A1 (en) * 2023-10-23 2025-05-01 Ohio State Innovation Foundation Heat and pain suppressing compounds

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4313958A (en) * 1980-10-24 1982-02-02 The Procter & Gamble Company Method of producing analgesia
DE3114593C1 (de) * 1981-04-10 1982-12-09 Fried. Krupp Gmbh, 4300 Essen Verfahren zur Gewinnung von Aroma- und Farbstoffen aus Paprika
US4564633A (en) * 1983-07-14 1986-01-14 The Procter & Gamble Company Compositions and methods useful for producing analgesia
US4592912A (en) * 1983-10-31 1986-06-03 Harriet Nickolaus Ache and pain relieving and preventing composition
US4702916A (en) * 1985-12-03 1987-10-27 Warner-Lambert Company Analgesic stick compositions
JPH02138289A (ja) * 1988-08-29 1990-05-28 Nippon Mektron Ltd 新規ジテルペノイド配糖体、それを薬効成分とする高血圧予防改善剤ならびにその製造法
US5021450A (en) * 1989-05-30 1991-06-04 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services New class of compounds having a variable spectrum of activities for capsaicin-like responses, compositions and uses thereof
CA2034261A1 (en) * 1990-01-17 1991-07-18 Mitsubishi Chemical Corporation Acyclic terpenes
JPH04198135A (ja) * 1990-11-28 1992-07-17 Rooman Kogyo:Kk 外用剤
US5665360A (en) * 1993-05-14 1997-09-09 Mann; Richard H. Method of treating peripheral neuropathies of the feet and legs
US5536263A (en) 1994-03-30 1996-07-16 Lectec Corporation Non-occulusive adhesive patch for applying medication to the skin
US5910512A (en) * 1994-04-18 1999-06-08 Healthline Laboratories, Inc. Topical analgesic using water soluble capsaicin
US5660830A (en) * 1994-09-14 1997-08-26 Anderson; Cleve Richard Solubilizing counter-irritants and concurrently extracting capsaicin from the same specific peppers
US5762963A (en) * 1995-06-07 1998-06-09 Emory University Method and compositions for controlling oral and pharyngeal pain using capsaicinoids
US5788982A (en) * 1995-06-16 1998-08-04 Nadoolman; Wolffe Method and composition for treating oral pain using capsaicin
US5869533A (en) 1996-04-23 1999-02-09 Holt; Stephen D. Non-irritating capsaicin formulations and applicators therefor
US5856361A (en) * 1996-04-23 1999-01-05 Medical Merchandising, Inc. Pain reliever and method of use
US5854291A (en) * 1996-04-23 1998-12-29 Medical Merchandising, Inc. Pain reliever and method of use
US6071507A (en) * 1996-07-10 2000-06-06 Zuluaga; Walter Mimocapsin
US5958418A (en) * 1997-01-22 1999-09-28 Johnson Prillerman; Kathleen O. External herbal composition for treating muscle aches and joint pain
US6060060A (en) * 1997-01-31 2000-05-09 Bmb Patent Holding Corporation Analgesic compositions from sweet peppers and methods of use thereof
US5827886A (en) * 1997-05-07 1998-10-27 Thione International, Inc. Composition for relief of arthritis-induced symptoms
CA2291335A1 (en) * 1997-05-27 1998-12-03 Algos Pharmaceutical Corporation Analgesic drug composition containing a capsaicinoid and potentiator therefor
GB9711962D0 (en) 1997-06-10 1997-08-06 Reckitt & Colmann Prod Ltd Therapeutically active compositions
US5885597A (en) * 1997-10-01 1999-03-23 Medical Research Industries,Inc. Topical composition for the relief of pain
JP3345744B2 (ja) 1998-03-04 2002-11-18 森永製菓株式会社 エステル結合を有する新規なカプサイシノイド様物質
US6197334B1 (en) * 1998-04-13 2001-03-06 Donald V. Renda Lozenge and method of making
US6159473A (en) * 1998-06-24 2000-12-12 Botanical Laboratories, Inc. Sore throat spray
JP3211027B2 (ja) * 1998-11-13 2001-09-25 丸石製薬株式会社 カプサイシン含有外用剤
US6086888A (en) * 1998-12-22 2000-07-11 Bmb Patent Holding Corporation Analgesic compositions from sweet bell peppers and methods of use thereof
US6552024B1 (en) * 1999-01-21 2003-04-22 Lavipharm Laboratories Inc. Compositions and methods for mucosal delivery
US6534086B1 (en) * 2000-03-06 2003-03-18 Metagenics, Inc. Composition and method for treatment of inflammation and pain in mammals
US6284797B1 (en) * 1999-04-12 2001-09-04 Donald A. Rhodes Topical treatment of pain and to promote healing
US6348501B1 (en) * 1999-09-29 2002-02-19 Medical Merchandising, Inc. Lotion compositions utilizing capsaicin
US6197823B1 (en) * 1999-09-29 2001-03-06 Medical Merchandising, Inc. Pain reliever and method of use
US6653352B2 (en) * 1999-09-29 2003-11-25 Medical Merchandising, Inc. Pain reliever and method of use
US6812254B1 (en) * 1999-09-29 2004-11-02 Medical Merchandising Inc. Pain reliever and method of use
US6573302B1 (en) * 1999-09-29 2003-06-03 Medical Merchandising, Inc. Cream utilizing capsaicin
US6689399B1 (en) * 2000-03-16 2004-02-10 James R. Dickson Transdermal delivery of an anti-inflammatory composition
US6589513B2 (en) * 2000-09-20 2003-07-08 Lesko-Care, L.L.C. Oral hygiene formulation and method of use
US6465022B1 (en) * 2001-06-19 2002-10-15 New Mexico Tech Research Foundation Method of providing an essential oil extract of capsicum, and the extract
US6586018B1 (en) * 2001-08-31 2003-07-01 Sabina Fasano Herbal composition
US6579543B1 (en) * 2002-02-22 2003-06-17 Jackie H. McClung Composition for topical application to skin
US7235270B2 (en) 2003-03-10 2007-06-26 Mayeux Jerry V Pain balm
EP1651241A2 (en) * 2003-07-28 2006-05-03 The Regents of the University of California, Office of Technology Transfer, University of California Methods for treating, preventing, or inhibiting injuries, cell membrane stabilization, and calcium mobilization using pseudopterosin compounds
JP2006212007A (ja) * 2005-02-01 2006-08-17 Kiichi Kusumoto ピーマンの胎座と隔壁の乾燥野菜
US20080103102A1 (en) 2006-10-27 2008-05-01 Bmb Patent Holding Corporation Therapeutic compositions and methods of treatment with capsianoside-type compounds

Also Published As

Publication number Publication date
WO2008052183A3 (en) 2009-04-09
US20140242150A1 (en) 2014-08-28
US9090645B2 (en) 2015-07-28
EP2096927A2 (en) 2009-09-09
US20080103102A1 (en) 2008-05-01
WO2008052183A2 (en) 2008-05-02
JP2014062099A (ja) 2014-04-10
JP5551301B2 (ja) 2014-07-16
EP2096927B1 (en) 2012-10-10
US20160129029A1 (en) 2016-05-12
EP2096927A4 (en) 2009-12-23
JP2010508299A (ja) 2010-03-18
US10195224B2 (en) 2019-02-05

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